Guide for the Care and Use of Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309154006
Total Pages : 246 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2011-01-27 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Guide for the Care and Use of Laboratory Animals -- Japanese Edition

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Author :
Publisher : National Academies Press
ISBN 13 : 0309100186
Total Pages : 142 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals -- Japanese Edition by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals -- Japanese Edition written by National Research Council and published by National Academies Press. This book was released on 1997-01-31 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Guide for the Care and Use of Laboratory Animals -- Korean Edition

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Author :
Publisher : National Academies Press
ISBN 13 : 0309103657
Total Pages : 128 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals -- Korean Edition by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals -- Korean Edition written by National Research Council and published by National Academies Press. This book was released on 2005-08-27 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.

Recognition and Alleviation of Distress in Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309108179
Total Pages : 137 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recognition and Alleviation of Distress in Laboratory Animals by : National Research Council

Download or read book Recognition and Alleviation of Distress in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2008-04-10 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. This new book from the Institute for Laboratory Animal Research (ILAR) at the National Research Council, Recognition and Alleviation of Distress in Laboratory Animals, focuses on the stress and distress which is experienced by animals when used in laboratory research. This book aims to educate laboratory animal veterinarians; students, researchers, and investigators; animal care staff, as well as animal welfare officers on the current scientific and ethical issues associated with stress and distress in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines. Recognition and Alleviation of Distress in Laboratory Animals focuses specifically on the scientific understanding of the causes and the functions of stress and distress, the transformation of stress to distress, and the identification of principles for the recognition and alleviation of distress. This book discusses the role of humane endpoints in situations of distress and principles for the minimization of distress in laboratory animals. It also identifies areas in which further scientific investigation is needed to improve laboratory animal welfare in order to adhere to scientific and ethical principles that promote humane care and practice.

Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research

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Author :
Publisher : National Academies Press
ISBN 13 : 0309138078
Total Pages : 118 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research by : National Research Council

Download or read book Scientific and Humane Issues in the Use of Random Source Dogs and Cats in Research written by National Research Council and published by National Academies Press. This book was released on 2009-12-30 with total page 118 pages. Available in PDF, EPUB and Kindle. Book excerpt: Scientific and Humane Issues in the Use of Random-Source Dogs and Cats in Research examines the value of random-source animals in biomedical research and the role of Class B dealers who acquire and resell live dogs and cats to research institutions. Findings include that, while some random-source dogs and cats may be necessary and desirable for National Institutes of Health (NIH)-funded research, there is no clear need to obtain those animals from Class B dealers. Several options for random-source animal acquisition already exist and additional options are recommended, which would further ensure the welfare of these animals and foster a positive public image for NIH. While the scientific community has recognized and responded to concerns for humane treatment of animals in research, government oversight has thus far been unable to fully enforce the Animal Welfare Act in regard to Class B dealers of live animals. Although the animals acquired by Class B dealers are destined for research-and NIH research in particular-the standard of care while in the possession of some Class B dealers requires an inordinate amount of government enforcement and is not commensurate with the policies of most NIH-funded research laboratories. This dichotomy of standards reflects poorly on public perceptions of NIH and jeopardizes animal welfare. This book will be crucial for NIH and other groups using random-source animals in research, including veterinary schools and research facilities. Animal welfare advocates, policy makers, and concerned pet owners will also find this a vital and informative work for reconciling the needs of research with the welfare of animals.

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.:/5 (846 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals

Download or read book Guide for the Care and Use of Laboratory Animals written by Institute of Laboratory Animal Resources (U.S.). Committee on Care and Use of Laboratory Animals and published by . This book was released on 1978 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 70 pages
Book Rating : 4.:/5 (22 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by :

Download or read book Guide for the Care and Use of Laboratory Animals written by and published by . This book was released on 1978 with total page 70 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 72 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : Institute of Laboratory Animal Resources (U.S.). Committee on Revision of the Guide for Laboratory Animals Facilities and Care

Download or read book Guide for the Care and Use of Laboratory Animals written by Institute of Laboratory Animal Resources (U.S.). Committee on Revision of the Guide for Laboratory Animals Facilities and Care and published by . This book was released on 1972 with total page 72 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Laboratory Animals

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Author :
Publisher : Academic Press
ISBN 13 : 012849879X
Total Pages : 466 pages
Book Rating : 4.1/5 (284 download)

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Book Synopsis Laboratory Animals by : Javier Guillen

Download or read book Laboratory Animals written by Javier Guillen and published by Academic Press. This book was released on 2017-11-03 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Users will find a broad picture of the regulations required in other areas of the world that will be essential to appropriately manage animal care and use programs. Offers a worldwide view and global compilation of regulations, guidelines and recommendations for laboratory animal research Provides insight into factors that play key roles in the regulatory framework for countries and geographic regions Compares and contrasts regulations in different regions Written in layman’s terms to easily understand legislation and regulations

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 0309588693
Total Pages : 140 pages
Book Rating : 4.3/5 (95 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : Institute for Laboratory Animal Research

Download or read book Guide for the Care and Use of Laboratory Animals written by Institute for Laboratory Animal Research and published by National Academies Press. This book was released on 1996-08-06 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been revised by a committee of experts, based on input from scientists and the public. The Guide incorporates recent research on commonly used species, including farm animals, and includes extensive references. It is organized around major components of animal use: Institutional policies and responsibilities. The committee discusses areas that require policy attention: the role and function of the Institutional Animal Care and Use Committee, protocols for animal care and use, occupational health and safety, personnel qualifications, and other areas. Animal environment, husbandry, and management. The committee offers guidelines on how to design and run a management program, addressing environment, nutrition, sanitation, behavioral and social issues, genetics, nomenclature, and more. Veterinary care. The committee discusses animal procurement and transportation, disease and preventive medicine, and surgery. The Guide addresses pain recognition and relief and issues surrounding euthanasia. Physical plant. The committee identifies design and construction issues, providing guidelines for animal-room doors, drainage, noise control, surgery, and other areas. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities--a resource of proven value, now updated and expanded. This revision will be important to researchers, animal care technicians, facilities managers, administrators at research institutions, policymakers involved in research issues, and animal welfare advocates.

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.:/5 (61 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by :

Download or read book Guide for the Care and Use of Laboratory Animals written by and published by . This book was released on 1972 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.:/5 (477 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : Institute of Laboratory Animal Resources (U.S.). Committee on Revision of the Guide for Laboratory Animals Facilities and Care

Download or read book Guide for the Care and Use of Laboratory Animals written by Institute of Laboratory Animal Resources (U.S.). Committee on Revision of the Guide for Laboratory Animals Facilities and Care and published by . This book was released on 1972 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Principles and Methods of Toxicology, Fifth Edition

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Author :
Publisher : CRC Press
ISBN 13 : 9780849337789
Total Pages : 2304 pages
Book Rating : 4.3/5 (377 download)

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Book Synopsis Principles and Methods of Toxicology, Fifth Edition by : A. Wallace Hayes

Download or read book Principles and Methods of Toxicology, Fifth Edition written by A. Wallace Hayes and published by CRC Press. This book was released on 2007-09-25 with total page 2304 pages. Available in PDF, EPUB and Kindle. Book excerpt: Founded on the paradox that all things are poisons and the difference between poison and remedy is quantity, the determination of safe dosage forms the base and focus of modern toxicology. In order to make a sound determination there must be a working knowledge of the biologic mechanisms involved and of the methods employed to define these mechanisms. While the vastness of the field and the rapid accumulation of data may preclude the possibility of absorbing and retaining more than a fraction of the available information, a solid understanding of the underlying principles is essential. Extensively revised and updated with four new chapters and an expanded glossary, this fifth edition of the classic text, Principles and Methods of Toxicology provides comprehensive coverage in a manageable and accessible format. New topics include 'toxicopanomics', plant and animal poisons, information resources, and non-animal testing alternatives. Emphasizing the cornerstones of toxicology-people differ, dose matters, and things change, the book begins with a review of the history of toxicology and followed by an explanation of basic toxicological principles, agents that cause toxicity, target organ toxicity, and toxicological testing methods including many of the test protocols required to meet regulatory needs worldwide. The book examines each method or procedure from the standpoint of technique and interpretation of data and discusses problems and pitfalls that may be associated with each. The addition of several new authors allow for a broader and more diverse treatment of the ever-changing and expanding field of toxicology. Maintaining the high-quality information and organizational framework that made the previous editions so successful, Principles and Methods of Toxicology, Fifth Edition continues to be a valuable resource for the advanced practitioner as well as the new disciple of toxicology.

Recognition and Alleviation of Pain in Laboratory Animals

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Author :
Publisher : National Academies Press
ISBN 13 : 030912834X
Total Pages : 198 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Recognition and Alleviation of Pain in Laboratory Animals by : National Research Council

Download or read book Recognition and Alleviation of Pain in Laboratory Animals written by National Research Council and published by National Academies Press. This book was released on 2010-01-14 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of animals in research adheres to scientific and ethical principles that promote humane care and practice. Scientific advances in our understanding of animal physiology and behavior often require theories to be revised and standards of practice to be updated to improve laboratory animal welfare. Recognition and Alleviation of Pain in Laboratory Animals, the second of two reports revising the 1992 publication Recognition and Alleviation of Pain and Distress in Laboratory Animals from the Institute for Laboratory Animal Research (ILAR), focuses on pain experienced by animals used in research. This book aims to educate laboratory animal veterinarians; students, researchers and investigators; Institutional Animal Care and Use Committee members; and animal care staff and animal welfare officers on the current scientific and ethical issues associated with pain in laboratory animals. It evaluates pertinent scientific literature to generate practical and pragmatic guidelines for recognizing and alleviating pain in laboratory animals, focusing specifically on the following areas: physiology of pain in commonly used laboratory species; pharmacologic and non-pharmacologic principles to control pain; identification of humane endpoints; and principles for minimizing pain associated with experimental procedures. Finally, the report identifies areas in which further scientific investigation is needed to improve laboratory animal welfare.

Guide for the Care and Use of Laboratory Animals

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Publisher :
ISBN 13 :
Total Pages : 83 pages
Book Rating : 4.:/5 (18 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by : National Research Council

Download or read book Guide for the Care and Use of Laboratory Animals written by National Research Council and published by . This book was released on 1985 with total page 83 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Guide for the Care and Use of Laboratory Animals

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Author :
Publisher :
ISBN 13 :
Total Pages : 100 pages
Book Rating : 4.:/5 (6 download)

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Book Synopsis Guide for the Care and Use of Laboratory Animals by :

Download or read book Guide for the Care and Use of Laboratory Animals written by and published by . This book was released on 1986 with total page 100 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Models for Assessing Countermeasures to Bioterrorism Agents

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Author :
Publisher : National Academies Press
ISBN 13 : 0309219094
Total Pages : 152 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Animal Models for Assessing Countermeasures to Bioterrorism Agents by : National Research Council

Download or read book Animal Models for Assessing Countermeasures to Bioterrorism Agents written by National Research Council and published by National Academies Press. This book was released on 2012-01-09 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Transformational Medical Technologies (TMT) has been a unique component of the U.S. Department of Defense (DoD) medical biodefense efforts since 2006. Its mission is to advance countermeasure research and development in support of the broader goal of the DoD to protect warfighters from emerging infectious diseases and future genetically engineered biological weapons. The TMT, using advanced science and technology approaches, focused on the development of roadspectrum countermeasures that target common host and pathogen pathways or enhance the host's immune response. Many of these pathogens are lethal or cause such debilitating diseases in humans that it is ethically inappropriate to test the efficacy of these countermeasures in human volunteers. In lieu of human participants, these products may be tested in animals and approved for human use under the provisions of the Food and Drug Administration (FDA)'s 2002 Animal Rule. The reliance on animal models for the development and licensure of medical countermeasures against biothreats is challenging for a number of reasons. The ad hoc Committee on Animal Models for Assessing Countermeasures to Bioterrorism Agents prepared a consensus report that would address the challenges stemming from developing and testing medical countermeasures against biothreat agents in animal models. Animal Models for Assessing Countermeasures to Bioterrorism Agents evaluates how well the existing TMT-employed or candidate animal models reflect the pathophysiology, clinical picture, and treatment of human disease as related to the agents of interest. The report addresses the process and/or feasibility of developing new animal models for critical biodefense research, placing emphasis on the need for a robust and expeditious validation process in terms of the FDA's Animal Rule. The report also evaluates alternatives to the use of animal models based on the premise of the Three Rs.