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Immune Microenvironment And Immunotherapy In Malignant Brain Tumors
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Book Synopsis Immune Microenvironment and Immunotherapy in Malignant Brain Tumors by : Liangxue Zhou
Download or read book Immune Microenvironment and Immunotherapy in Malignant Brain Tumors written by Liangxue Zhou and published by Frontiers Media SA. This book was released on 2023-12-19 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Interconnection Between the Tumor Microenvironment and Immunotherapy in Brain Tumors by : Quan Cheng
Download or read book The Interconnection Between the Tumor Microenvironment and Immunotherapy in Brain Tumors written by Quan Cheng and published by Frontiers Media SA. This book was released on 2023-06-08 with total page 418 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunotherapy for Tumor in the Brain: Insights From – and For – Other Tumor Sites by : Lois A. Lampson
Download or read book Immunotherapy for Tumor in the Brain: Insights From – and For – Other Tumor Sites written by Lois A. Lampson and published by Frontiers Media SA. This book was released on 2018-07-09 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor immunotherapy has now shown its promise for many, its disappointments and failings for others. Going forward, brain tumor patients can both benefit and contribute. Tumor immunotherapy is steadily progressing. As experience accumulates, it is important to consider its generality. The reviews herein emphasize the brain’s place among other tumor sites. Two major topics are addressed. THE SITE: WHAT CAN WE EXPECT FROM IMMUNOTHERAPY WHEN THE TARGET IS IN THE BRAIN? Experience with immunotherapy for different targets in the brain, including tumor and also pathogens, is reviewed. Long-standing assumptions are confronted. The potential for beneficial responses is stressed. BRAIN TUMOR IMMUNOTHERAPY: WHAT HAVE WE LEARNED SO FAR? Clinical experience with brain tumor immunotherapy, from a variety of centers, is reviewed. Primary tumors, emphasizing glioblastoma, and brain metastases are each considered.
Book Synopsis The Immunology and Biology of Brain Tumors by : Michael Graner
Download or read book The Immunology and Biology of Brain Tumors written by Michael Graner and published by MDPI. This book was released on 2021-05-04 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunotherapy has become a viable treatment modality for a variety of cancers (and referred to as Science Magazine’s “Breakthrough of the Year” in 2013, as well as ASCO’s “Advance of the Year” in both 2016 and 2017). This Special Issue is focused on the relevance of immunobiology in brain tumors, touching on elements of immune suppression, immune stimulation, and the immune microenvironment, with culminations in translational immunotherapy.
Book Synopsis Translational Immunotherapy of Brain Tumors by : John H. Sampson
Download or read book Translational Immunotherapy of Brain Tumors written by John H. Sampson and published by Academic Press. This book was released on 2017-02-06 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors
Book Synopsis Brain Tumor Immunotherapy by : Linda M. Liau
Download or read book Brain Tumor Immunotherapy written by Linda M. Liau and published by Springer Science & Business Media. This book was released on 2000-11-10 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.
Book Synopsis Immunotherapeutic Strategies for the Treatment of Glioma by : Christopher Jackson
Download or read book Immunotherapeutic Strategies for the Treatment of Glioma written by Christopher Jackson and published by Academic Press. This book was released on 2021-09-10 with total page 190 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunotherapeutic Strategies for the Treatment of Glioma provides a review of the current state of immunotherapy for primary brain tumors. The topic is of interest to patients, clinicians, and researchers alike, particularly given the recent failure of large clinical trials. This book serves as an overview of the most promising approaches in the field and provides a foundation for considering novel and combination therapies moving forward. The book discusses several types of immunotherapies for glioma, such as peptide, dendritic cell and heat shock protein vaccines; immune checkpoint blockade; myeloid cells as target; oncolytic viruses; and CAR T cell therapy. Additionally, it discusses the mechanisms of immune suppression in patients and immunogenomics. This volume is a valuable source for cancer researchers, oncologists and several members of biomedical field who are interested in novel strategies to fight glioblastoma. Summarizes the work in immunotherapy for glioma to-date, including the available evidence from preclinical studies and clinical trials Reviews the challenges and successes of the most promising strategies for brain tumor immunotherapy Provides a foundation for considering novel and combination therapies moving forward
Book Synopsis Tumor Immunology and Immunotherapy - Integrated Methods Part B by :
Download or read book Tumor Immunology and Immunotherapy - Integrated Methods Part B written by and published by Academic Press. This book was released on 2020-04-01 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy - Integrated Methods Part B, Volume 636 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this update include Quantification methods of Transforming Growth Factor beta (TGF??) activity in the setting of cancer immunotherapy, Decoding cancer cell death-driven immune cell recruitment: An in vivo method for site-of-vaccination analyses, Tracking and interrogating tissue-resident and recruited microglia in brain tumors, Metabolomics and lipidomics of the tumor microenvironment, Monitoring abscopal responses to radiation in mice, and much more. Provides an array of authors who are authorities in the field Presents comprehensiveness coverage of the topics Includes a broad level of detail and in-depth coverage
Book Synopsis Impact of the Glioma Microenvironment on Antitumor Immunity by : Valérie Dutoit
Download or read book Impact of the Glioma Microenvironment on Antitumor Immunity written by Valérie Dutoit and published by Frontiers Media SA. This book was released on 2022-01-31 with total page 212 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tumor Microenvironment by : Peter P. Lee
Download or read book Tumor Microenvironment written by Peter P. Lee and published by Springer Nature. This book was released on 2020-03-25 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the biological processes relevant to the immune phenotypes of cancer and their significance for immune responsiveness, based on the premise that malignant cells manipulate their surroundings through an evolutionary process that is controlled by interactions with innate immune sensors as well as the adaptive recognition of self/non-self. Checkpoint inhibitor therapy is now an accepted new form of cancer treatment. Other immuno-oncology approaches, such as adoptive cell therapy and metabolic inhibitors, have also shown promising results for specific indications. Immune resistance is common, however, limiting the efficacy of immunotherapy in many common cancer types. The reasons for such resistance are diverse and peculiar to the immune landscapes of individual cancers, and to the treatment modality used. Accordingly, approaches to circumvent resistance need to take into account context-specific genetic, biological and environmental factors that may affect the cancer immune cycle, and which can best be understood by studying the target tissue and correlated systemic immune markers. Understanding the major requirements for the evolutionary process governing human cancer growth in the immune-competent host will guide effective therapeutic choices that are tailored to the biology of individual cancers.
Download or read book Brain Tumors written by Amit Agrawal and published by BoD – Books on Demand. This book was released on 2022-04-20 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Brain tumors comprise a spectrum of histological patterns. Their presentation and management depend on their location, size, and grade of lesions. This book is a collection of high-quality research work from global experts on brain tumors, including meningiomas, and their treatment.
Book Synopsis Targeting the Tumor Microenvironment for a More Effective and Efficient Cancer Immunotherapy by : Salem Chouaib
Download or read book Targeting the Tumor Microenvironment for a More Effective and Efficient Cancer Immunotherapy written by Salem Chouaib and published by Frontiers Media SA. This book was released on 2020-07-02 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy by : Pawel Kalinski
Download or read book Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy written by Pawel Kalinski and published by Springer. This book was released on 2017-12-22 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: The tumor microenvironment has become a very important and hot topic in cancer research within the past few years. The tumor microenvironment is defined as the normal cells, molecules, and blood vessels that surround and feed a tumor cell. As many scientists have realized, studying the tumor microenvironment has become critical to moving the field forward, since there are many players in a tumor’s localized and surrounding area, which can significantly change cancer cell behavior. There is a dual relationship wherein the tumor can change its microenvironment and the microenvironment can affect how a tumor grows and spreads. Tumor Microenvironment in Cancer Progression and Cancer Therapy aims to shed light on the mechanisms, factors, and mediators that are involved in the cancer cell environment. Recent studies have demonstrated that in addition to promoting tumor progression and protecting tumor cells from the spontaneous immune-mediated rejection and different forms of cancer therapeutics, tumor microenvironment can also be a target and mediator of both standard and newly-emerging forms of cancer therapeutics. Thus, the dual role of the tumor microenvironment is the integral focus of the volume. The volume highlights the bi-directional interactions between tumor cells and non-malignant tumor component during tumor progression and treatment. It also focuses on the three groups of the reactive tumor component: stromal cells, blood vessels and the infiltrating immune cells. These three groups are discussed under the lens of their role in promoting tumor growth, shielding the tumor from rejection and from standard forms of cancer therapies. They are emerging as targets and mediators of standard and new forms of potential therapy.
Book Synopsis Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy by : Qian Xiao
Download or read book Immune Modulation in Tumor Microenvironment: New Perspectives for Cancer Immunotherapy written by Qian Xiao and published by Frontiers Media SA. This book was released on 2023-02-01 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cancer Plasticity and the Microenvironment: Implications for Immunity and Therapy Response by : Petranel T. Ferrao
Download or read book Cancer Plasticity and the Microenvironment: Implications for Immunity and Therapy Response written by Petranel T. Ferrao and published by Frontiers Media SA. This book was released on 2019-11-01 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer cells can change and adapt, especially within the host environment; a phenomenon known as cancer plasticity. Several factors, including the immune system can influence, and be influenced by, cancer plasticity which in turn can impact upon patient responses to treatment. As such, we currently face several challenges for implementing combination therapies as effective cancer treatment strategies. We have compiled a topic with a number of articles that emphasize the various aspects of cancer plasticity, describing in particular the important role of the tumor microenvironment. As we embark on a new era of precision medicine with multi-modal therapies for improving patient outcomes, this topic highlights some relevant points for consideration that are pertinent to the incorporation and effective use of new treatments as part of cancer treatment regimens, including immune-modulating drugs.
Book Synopsis Tumor Microenvironment and Resistance to Current Therapies by : Ahmed Lasfar
Download or read book Tumor Microenvironment and Resistance to Current Therapies written by Ahmed Lasfar and published by Frontiers Media SA. This book was released on 2020-01-27 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Tumor Immunology and Immunotherapy - Integrated Methods Part A by :
Download or read book Tumor Immunology and Immunotherapy - Integrated Methods Part A written by and published by Academic Press. This book was released on 2020-02-28 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry, High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more. Authored by leaders in the field of enzymology Provides a comprehensiveness level of discussion on the field Presents a highly specialized group of topics that delve deep into new updates and future prospects
