Illuminating DNA Packaging in Sperm Chromatin

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Publisher :
ISBN 13 :
Total Pages : 142 pages
Book Rating : 4.:/5 (113 download)

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Book Synopsis Illuminating DNA Packaging in Sperm Chromatin by : Daniel Kirchhoff

Download or read book Illuminating DNA Packaging in Sperm Chromatin written by Daniel Kirchhoff and published by . This book was released on 2019 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:

A Clinician's Guide to Sperm DNA and Chromatin Damage

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Author :
Publisher : Springer
ISBN 13 : 3319718150
Total Pages : 598 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis A Clinician's Guide to Sperm DNA and Chromatin Damage by : Armand Zini

Download or read book A Clinician's Guide to Sperm DNA and Chromatin Damage written by Armand Zini and published by Springer. This book was released on 2018-03-05 with total page 598 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.

Introduction to Epigenetics

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Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Introduction to Epigenetics by : Renato Paro

Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

FISH Technology

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Publisher : Elsevier
ISBN 13 : 9783540672760
Total Pages : 508 pages
Book Rating : 4.6/5 (727 download)

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Book Synopsis FISH Technology by : Bernd W. Rautenstrauß

Download or read book FISH Technology written by Bernd W. Rautenstrauß and published by Elsevier. This book was released on 2002-02-14 with total page 508 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fluorescence in situ hybridization (FISH) has been developed as a powerful technology which allows direct visualisation or localisation of genomic alterations. The technique has been adopted to a range of applications in both medicine, especially in the areas of diagnostic cytogenetics, and biology. Topics described in this manual include: FISH on native human tissues, such as blood, bone marrow, epithelial cells, hair root cells, amniotic fluid cells, human sperm cells; FISH on archival human tissues, such as formalin fixed and paraffin embedded tissue sections, cryofixed tissue; simultaneous detection of apoptosis and xpression of apoptosis-related genes; comparative genomic ybridization; and special FISH techniques.

Infertility in the Male

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Publisher : Cambridge University Press
ISBN 13 : 1139483242
Total Pages : 691 pages
Book Rating : 4.1/5 (394 download)

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Book Synopsis Infertility in the Male by : Larry I. Lipshultz

Download or read book Infertility in the Male written by Larry I. Lipshultz and published by Cambridge University Press. This book was released on 2009-09-24 with total page 691 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of this canonical text on male reproductive medicine will cement the book's market-leading position. Practitioners across many specialties - including urologists, gynecologists, reproductive endocrinologists, medical endocrinologists and many in internal medicine and family practice – will see men with suboptimal fertility and reproductive problems. The book provides an excellent source of timely, well-considered information for those training in this young and rapidly evolving field. While several recent books provide targeted 'cookbooks' for those in a male reproductive laboratory, or quick reference for practising generalists, the modern, comprehensive reference providing both a background for male reproductive medicine as well as clinical practice information based on that foundation has been lacking until now. The book has been extensively revised with a particular focus on modern molecular medicine. Appropriate therapeutic interventions are highlighted throughout.

Genetic Damage in Human Spermatozoa

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Publisher : Springer Science & Business Media
ISBN 13 : 1461477832
Total Pages : 206 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Genetic Damage in Human Spermatozoa by : Elisabetta Baldi

Download or read book Genetic Damage in Human Spermatozoa written by Elisabetta Baldi and published by Springer Science & Business Media. This book was released on 2013-08-16 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Genetic Damage in Human Spermatozoa

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Publisher : Springer
ISBN 13 : 3030216640
Total Pages : 216 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Genetic Damage in Human Spermatozoa by : Elisabetta Baldi

Download or read book Genetic Damage in Human Spermatozoa written by Elisabetta Baldi and published by Springer. This book was released on 2019-07-12 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: There are several types of damage that can be found in the male gamete. This book covers the genetic damage in spermatozoa that can originate during spermatogenesis, or during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as to the protocols to cryopreserve and to select spermatozoa in assisted reproduction techniques. The purpose of this book is to provide a comprehensive resource for all possible DNA damages in sperm, the relation to fertility and infertility, and possible transgenerational heritable effects.

Sperm Chromatin

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Publisher : Springer
ISBN 13 : 9781493951321
Total Pages : 512 pages
Book Rating : 4.9/5 (513 download)

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Book Synopsis Sperm Chromatin by : Armand Zini

Download or read book Sperm Chromatin written by Armand Zini and published by Springer. This book was released on 2016-08-23 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sperm DNA damage is common and has been associated with reduced rates of conception, impaired embryonic development and increased risk of miscarriage. Although the exact causes of sperm DNA damage are unknown, it is clear that infertile men possess substantially higher levels of sperm DNA damage than do fertile men. Written by leading, internationally renowned clinicians and basic scientists with expertise in sperm DNA, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction provides readers with a thoughtful and comprehensive review of the biological and clinical significance of sperm DNA damage. The work covers the fundamental principles of sperm chromatin architecture and function, the proposed modes of DNA damage and repair, the tests of sperm DNA damage, the clinical aspects of DNA damage and the impact of DNA damage on reproductive outcome. Unlike any other title on the topic, Sperm Chromatin: Biological and Clinical Applications in Male Infertility and Assisted Reproduction is an invaluable addition to the literature and will serve as an indispensable resource for basic scientists with an interest in sperm biology and for urologists, gynecologists, reproductive endocrinologists, and embryologists working in the field of infertility.

Human Reproduction

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Publisher : John Wiley & Sons
ISBN 13 : 1118849582
Total Pages : 454 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Human Reproduction by : Heide Schatten

Download or read book Human Reproduction written by Heide Schatten and published by John Wiley & Sons. This book was released on 2017-03-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: In vitro fertilization (IVF) and other assisted reproductive technologies (ART) have become a significant part of human reproduction, with already one in 50 children worldwide being born through ART and the demand steadily increasing. To accommodate the various kinds of infertility problems, new methods have been developed to increase IVF and ART success rates and it has also become possible to treat sperm, eggs, and embryos in culture to improve reproductive success, to increase the health state of an embryo, and to prevent disease in the developing child. Human Reproduction: Updates and New Horizons focuses on recent developments and new approaches to study egg and sperm cells and embryo development, as well as addressing the increasing demand for IVF and ART to overcome infertility problems of various kinds that are encountered by an increasing number of couples worldwide. The book includes 10 chapters written by experts in their specific fields to provide information on sperm selection techniques and their relevance to ART; In vitro maturation of human oocytes: current practices and future promises; Molecular biology of endometriosis; Novel immunological aspects for the treatment of age-induced ovarian and testicular infertility, other functional diseases, and early and advanced cancer immunotherapy; Mitochondrial manipulation for infertility treatment and disease prevention; Novel imaging techniques to assess gametes and preimplantation embryos; Clinical application of methods to select in vitro fertilized embryos; New horizons/developments in time-lapse morphokinetic analysis of mammalian embryos; The non-human primate model for early human development; Cytoskeletal functions, defects, and dysfunctions affecting human fertilization and embryo development. This book will appeal to a large interdisciplinary audience, including researchers from both the basic science and medical communities. It will be a valuable reference for IVF clinicians, patients and prospective patients who are considering ART procedures, embryologists, cell biologists and students in the field of reproduction.

Chromosome Architecture

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Publisher : Humana
ISBN 13 : 9781493936298
Total Pages : 0 pages
Book Rating : 4.9/5 (362 download)

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Book Synopsis Chromosome Architecture by : Mark C. Leake

Download or read book Chromosome Architecture written by Mark C. Leake and published by Humana. This book was released on 2016-06-10 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume details a valuable collection of protocols and reviews, such as emerging experimental and theoretical approaches. These approaches have resulted in a substantial improvement in the understanding of chromosome architecture. Chromosome Architecture: Methods and Protocols guides readers through cutting-edge interdisciplinary methods which allow for an understanding of architecture of chromosomes with exceptionally enhanced resolution, both in terms of space and time. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Chromosome Architecture: Methods and Protocols aims to ensure successful results in the further study of this vital field.

The Nucleus

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Publisher :
ISBN 13 : 9780879698942
Total Pages : 0 pages
Book Rating : 4.6/5 (989 download)

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Book Synopsis The Nucleus by : Tom Misteli

Download or read book The Nucleus written by Tom Misteli and published by . This book was released on 2011 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written and edited by experts in the field, this volume includes contributions discussing the relationship between nuclear structure and function, the various nuclear bodies that have been identified, and the organization of the nuclear lamina and nuclear pore complex.

Chromosomes

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Publisher :
ISBN 13 :
Total Pages : 248 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Chromosomes by :

Download or read book Chromosomes written by and published by . This book was released on 1990 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Oxford Handbook of Developmental Psychology, Vol. 1

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Publisher : Oxford University Press
ISBN 13 : 0199958459
Total Pages : 1049 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Oxford Handbook of Developmental Psychology, Vol. 1 by : Philip David Zelazo

Download or read book The Oxford Handbook of Developmental Psychology, Vol. 1 written by Philip David Zelazo and published by Oxford University Press. This book was released on 2013-03-21 with total page 1049 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook provides a comprehensive survey of what is now known about psychological development, from birth to biological maturity, and it highlights how cultural, social, cognitive, neural, and molecular processes work together to yield human behavior and changes in human behavior.

Physical Biology of the Cell

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Publisher : Garland Science
ISBN 13 : 1134111584
Total Pages : 1089 pages
Book Rating : 4.1/5 (341 download)

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Book Synopsis Physical Biology of the Cell by : Rob Phillips

Download or read book Physical Biology of the Cell written by Rob Phillips and published by Garland Science. This book was released on 2012-10-29 with total page 1089 pages. Available in PDF, EPUB and Kindle. Book excerpt: Physical Biology of the Cell is a textbook for a first course in physical biology or biophysics for undergraduate or graduate students. It maps the huge and complex landscape of cell and molecular biology from the distinct perspective of physical biology. As a key organizing principle, the proximity of topics is based on the physical concepts that

Single Cell Analysis

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Publisher : Springer
ISBN 13 : 9811044996
Total Pages : 277 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Single Cell Analysis by : J. Paul Robinson

Download or read book Single Cell Analysis written by J. Paul Robinson and published by Springer. This book was released on 2017-04-18 with total page 277 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.

Recurrent Implantation Failure

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Publisher : Springer
ISBN 13 : 331971967X
Total Pages : 221 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Recurrent Implantation Failure by : Jason M. Franasiak

Download or read book Recurrent Implantation Failure written by Jason M. Franasiak and published by Springer. This book was released on 2018-04-03 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnormalities of the hematologic and endocrine system, as well as those of the anatomy and microbiome, are described in detail. Last but no less important, the psychological stress and treatment of patients experiencing RIF is discussed. Assisted reproductive technology (ART) success has increased substantially over the past three decades. However, despite these advances, recurrent implantation failure is still a common issue confronting patients and clinicians, and RIF represents one of the greatest challenges in ART and remains a source of frustration and disappointment for patients, clinicians, and researchers involved in the process. Providing an in-depth investigation into the pathophysiology and biological mechanisms of RIF and its clinical management, this will be an excellent resource for reproductive endocrinologists and infertility specialists.

Male-mediated Developmental Toxicity

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Publisher : Royal Society of Chemistry
ISBN 13 : 0854048472
Total Pages : 318 pages
Book Rating : 4.8/5 (54 download)

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Book Synopsis Male-mediated Developmental Toxicity by : Diana Anderson

Download or read book Male-mediated Developmental Toxicity written by Diana Anderson and published by Royal Society of Chemistry. This book was released on 2007 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: Male germ line mutagenesis and the effects on developmental defects in the next generation.