IEH Report on Variability and Susceptibility in Human Response to Occupational Exposure to Chemicals in the UK

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Publisher :
ISBN 13 :
Total Pages : 172 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis IEH Report on Variability and Susceptibility in Human Response to Occupational Exposure to Chemicals in the UK by : Medical Research Council (Great Britain). Institute for Environment and Health

Download or read book IEH Report on Variability and Susceptibility in Human Response to Occupational Exposure to Chemicals in the UK written by Medical Research Council (Great Britain). Institute for Environment and Health and published by . This book was released on 2002 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment

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Publisher : CRC Press
ISBN 13 : 1439805938
Total Pages : 272 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment by : David A. Eckerman

Download or read book Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment written by David A. Eckerman and published by CRC Press. This book was released on 1998-08-25 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.

Human Variability in Response to Chemical Exposures

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Publisher : International Life Science Inst
ISBN 13 : 9781578810000
Total Pages : 257 pages
Book Rating : 4.8/5 (1 download)

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Book Synopsis Human Variability in Response to Chemical Exposures by : David A. Neumann

Download or read book Human Variability in Response to Chemical Exposures written by David A. Neumann and published by International Life Science Inst. This book was released on 1998 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, & Risk Assessment recognizes & addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive & developmental effects, effects on the nervous system & lungs, & cancer. Their reports convey both the current state of scientific understanding of response variability & the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community & others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed & illustrated with published data. This authoritative work indicates that, in the case of certain chemicals & in the context of certain specific toxic effects, we have considerable ability to predictively & quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity & quality of information available on response variability & increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.

Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment

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Publisher : CRC Press
ISBN 13 : 9780849328053
Total Pages : 272 pages
Book Rating : 4.3/5 (28 download)

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Book Synopsis Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment by : David A. Neumann

Download or read book Human Variability in Response to Chemical Exposures Measures, Modeling, and Risk Assessment written by David A. Neumann and published by CRC Press. This book was released on 1998-08-25 with total page 272 pages. Available in PDF, EPUB and Kindle. Book excerpt: and for those interested in toxic effects of chemicals on humans, Human Variability in Response to Chemical Exposures: Measures, Modeling, and Risk Assessment recognizes and addresses the increasing awareness that individual biological differences be reflected when assessing human health risks associated with exposure to chemicals. Eight original manuscripts, commissioned by the ILSI Risk Science Institute, address the evidence for variability in human response to chemicals associated with reproductive and developmental effects, effects on the nervous system and lungs, and cancer. Their reports convey both the current state of scientific understanding of response variability and the genetic basis for such observations. This book recognizes that understanding of variability in response is critical in accounting for interindividual variability in susceptibility and, hence, risk, if the regulatory community and others are expected to characterize human health risks associated with exposure to chemicals. Models for incorporating measures of response variability in the risk assessment process are critically reviewed and illustrated with published data. This authoritative work indicates that, in the case of certain chemicals and in the context of certain specific toxic effects, we have considerable ability to predictively and quantitatively characterize human variability, but, in the majority of cases, our ability to do so is limited. If we improve both quantity and quality of information available on response variability and increase our understanding of target tissue dosimetry, we should be better able to account for variability in human susceptibility to the toxic effects of chemicals.

Survival and Sustainability

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Publisher : Springer Science & Business Media
ISBN 13 : 3540959912
Total Pages : 1468 pages
Book Rating : 4.5/5 (49 download)

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Book Synopsis Survival and Sustainability by : Hüseyin Gökçekus

Download or read book Survival and Sustainability written by Hüseyin Gökçekus and published by Springer Science & Business Media. This book was released on 2011-03-23 with total page 1468 pages. Available in PDF, EPUB and Kindle. Book excerpt: The International Conference on Environment: Survival and Sustainability, held at the Near East University, Nicosia, Northern Cyprus 19-24 February 2007, dealt with environmental threats and proposed solutions at all scales. The 21 themes addressed by the conference fell into four broad categories; Threats to Survival and Sustainability; Technological Advances towards Survival and Sustainability; Activities and Tools for Social Change; Defining Goals for Sustainable Societies. Activities and tools that move the society towards greater sustainability were emphasized at the conference. These included environmental law and ethics, environmental knowledge, technology and information systems, media, environmental awareness, education and lifelong learning, the use of literature for environmental awareness, the green factor in politics, international relations and environmental organizations. The breadth of the issues addressed at the conference made clear the need for greatly increased interdisciplinary and international collaboration the survival and sustainability concept. The exchanges at the conference represent a step in this direction.

British National Bibliography for Report Literature

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Publisher :
ISBN 13 :
Total Pages : 470 pages
Book Rating : 4.:/5 (334 download)

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Book Synopsis British National Bibliography for Report Literature by :

Download or read book British National Bibliography for Report Literature written by and published by . This book was released on 1998 with total page 470 pages. Available in PDF, EPUB and Kindle. Book excerpt:

WHO Guidelines for Indoor Air Quality

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Publisher : World Health Organization
ISBN 13 :
Total Pages : 488 pages
Book Rating : 4.:/5 (1 download)

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Book Synopsis WHO Guidelines for Indoor Air Quality by :

Download or read book WHO Guidelines for Indoor Air Quality written by and published by World Health Organization. This book was released on 2010 with total page 488 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Molecular Epidemiology

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Publisher : Academic Press
ISBN 13 : 0323138578
Total Pages : 609 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Molecular Epidemiology by : Paul A. Schulte

Download or read book Molecular Epidemiology written by Paul A. Schulte and published by Academic Press. This book was released on 2012-12-02 with total page 609 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will serve as a primer for both laboratory and field scientists who are shaping the emerging field of molecular epidemiology. Molecular epidemiology utilizes the same paradigm as traditional epidemiology but uses biological markers to identify exposure, disease or susceptibility. Schulte and Perera present the epidemiologic methods pertinent to biological markers. The book is also designed to enumerate the considerations necessary for valid field research and provide a resource on the salient and subtle features of biological indicators.

Principles of Route-to-route Extrapolation for Risk Assessment

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Publisher : Elsevier Publishing Company
ISBN 13 : 9780444015822
Total Pages : 322 pages
Book Rating : 4.0/5 (158 download)

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Book Synopsis Principles of Route-to-route Extrapolation for Risk Assessment by : Timothy R. Gerrity

Download or read book Principles of Route-to-route Extrapolation for Risk Assessment written by Timothy R. Gerrity and published by Elsevier Publishing Company. This book was released on 1990 with total page 322 pages. Available in PDF, EPUB and Kindle. Book excerpt:

The Airliner Cabin Environment and the Health of Passengers and Crew

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Publisher : National Academies Press
ISBN 13 : 0309082897
Total Pages : 345 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis The Airliner Cabin Environment and the Health of Passengers and Crew by : National Research Council

Download or read book The Airliner Cabin Environment and the Health of Passengers and Crew written by National Research Council and published by National Academies Press. This book was released on 2002-02-03 with total page 345 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although poor air quality is probably not the hazard that is foremost in peoples' minds as they board planes, it has been a concern for years. Passengers have complained about dry eyes, sore throat, dizziness, headaches, and other symptoms. Flight attendants have repeatedly raised questions about the safety of the air that they breathe. The Airliner Cabin Environment and the Health of Passengers and Crew examines in detail the aircraft environmental control systems, the sources of chemical and biological contaminants in aircraft cabins, and the toxicity and health effects associated with these contaminants. The book provides some recommendations for potential approaches for improving cabin air quality and a surveillance and research program.

Night Noise Guidelines for Europe

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Publisher : WHO Regional Office Europe
ISBN 13 : 9289041730
Total Pages : 183 pages
Book Rating : 4.2/5 (89 download)

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Book Synopsis Night Noise Guidelines for Europe by : Charlotte Hurtley

Download or read book Night Noise Guidelines for Europe written by Charlotte Hurtley and published by WHO Regional Office Europe. This book was released on 2009 with total page 183 pages. Available in PDF, EPUB and Kindle. Book excerpt: The WHO Regional Office for Europe set up a working group of experts to provide scientific advice to the Member States for the development of future legislation and policy action in the area of assessment and control of night noise exposure. The working group reviewed available scientific evidence on the health effects of night noise, and derived health-based guideline values. In December 2006, the working group and stakeholders from industry, government and nongovernmental organizations reviewed and reached general agreement on the guideline values and key texts for the final document of the "Night noise guidelines for Europe". Considering the scientific evidence on the thresholds of night noise exposure indicated by "Lnight,outside" [L suffix night,outside] as defined in the Environmental Noise Directive (2002/49/EC), an Lnight, outside of 40 dB should be the target of the night noise guideline (NNG) to protect the public, including the most vulnerable groups such as children, the chronically ill and the elderly. "Lnight,outside" value of 55 dB is recommended as an interim target for the countries where the NNG cannot be achieved in the short term for various reasons, and where policy-makers choose to adopt a stepwise approach. These guidelines are applicable to the Member States of the European Region, and may be considered as an extension to, as well as an update of, the previous WHO "Guidelines for community noise" (1999). [Ed.]

Chemical-specific Adjustment Factors for Interspecies Differences and Human Variability

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Publisher : World Health Organization
ISBN 13 : 9241546786
Total Pages : 101 pages
Book Rating : 4.2/5 (415 download)

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Book Synopsis Chemical-specific Adjustment Factors for Interspecies Differences and Human Variability by : International Program on Chemical Safety

Download or read book Chemical-specific Adjustment Factors for Interspecies Differences and Human Variability written by International Program on Chemical Safety and published by World Health Organization. This book was released on 2005-12-31 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: Published under the joint sponsorship of the WHO, the ILO and the UNEP and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals. On cover: IPCS: International Programme on Chemical Safety

Science and Decisions

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Publisher : National Academies Press
ISBN 13 : 0309120462
Total Pages : 422 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Science and Decisions by : National Research Council

Download or read book Science and Decisions written by National Research Council and published by National Academies Press. This book was released on 2009-03-24 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Risk assessment has become a dominant public policy tool for making choices, based on limited resources, to protect public health and the environment. It has been instrumental to the mission of the U.S. Environmental Protection Agency (EPA) as well as other federal agencies in evaluating public health concerns, informing regulatory and technological decisions, prioritizing research needs and funding, and in developing approaches for cost-benefit analysis. However, risk assessment is at a crossroads. Despite advances in the field, risk assessment faces a number of significant challenges including lengthy delays in making complex decisions; lack of data leading to significant uncertainty in risk assessments; and many chemicals in the marketplace that have not been evaluated and emerging agents requiring assessment. Science and Decisions makes practical scientific and technical recommendations to address these challenges. This book is a complement to the widely used 1983 National Academies book, Risk Assessment in the Federal Government (also known as the Red Book). The earlier book established a framework for the concepts and conduct of risk assessment that has been adopted by numerous expert committees, regulatory agencies, and public health institutions. The new book embeds these concepts within a broader framework for risk-based decision-making. Together, these are essential references for those working in the regulatory and public health fields.

Risk Management for Water and Wastewater Utilities

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Publisher : IWA Publishing
ISBN 13 : 1780407475
Total Pages : 180 pages
Book Rating : 4.7/5 (84 download)

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Book Synopsis Risk Management for Water and Wastewater Utilities by : Simon Pollard

Download or read book Risk Management for Water and Wastewater Utilities written by Simon Pollard and published by IWA Publishing. This book was released on 2016-05-15 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: Water risks and security are a major global hazard in the 21st century and it is essential that water professionals have a solid grounding in the principles of preventative risk management. This second edition of the key textbook, Risk Management for Water and Wastewater Utilities, extends beyond first principles and examines the practicalities of resilience and vulnerability assessment, strategic risk appraisal and the interconnectedness of water utility risks in a networked infrastructure. It provides an up-dated overview of tools and techniques for risk management in the context of the heightened expectations for sound risk governance that are being made of all water and wastewater utilities. Risk Management for Water and Wastewater Utilities provides a valuable starting point for newly appointed risk managers in the utility sector and offers MSc level self-paced study with self-assessment questions and abbreviated answers, key learning points, case studies and worked examples.

The Ethics of Research Involving Animals

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Publisher :
ISBN 13 : 9781904384106
Total Pages : 335 pages
Book Rating : 4.3/5 (841 download)

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Book Synopsis The Ethics of Research Involving Animals by :

Download or read book The Ethics of Research Involving Animals written by and published by . This book was released on 2005-01-01 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: A report of the Nuffield Council on Bioethics working party investigating the ethical issues of research involving animals.

Marine Biotoxins

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Publisher : Food & Agriculture Org.
ISBN 13 : 9789251051290
Total Pages : 300 pages
Book Rating : 4.0/5 (512 download)

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Book Synopsis Marine Biotoxins by : Hans P. Egmond

Download or read book Marine Biotoxins written by Hans P. Egmond and published by Food & Agriculture Org.. This book was released on 2004 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: This paper provides an extensive review of different aspects of five shellfish-poisoning syndromes (paralytic, diarrhoeic, amnesic, neurologic and azapiracid), as well as one fish-poisoning syndrome (ciguatera fish poisoning), and discusses in detail the causative toxins produced by marine organisms, chemical structures and analytical methods of the toxins, habitat and occurrence of the toxin-producing organisms, case studies and existing regulations. Based on this analysis, risk assessments are carried out for each of the toxins, and recommendations are elaborated to improve the management of these risks in order to reduce the harmful effect of these toxins on public health.

Toxicological Risk Assessment of Chemicals

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Publisher : CRC Press
ISBN 13 : 1420006940
Total Pages : 450 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Toxicological Risk Assessment of Chemicals by : Elsa Nielsen

Download or read book Toxicological Risk Assessment of Chemicals written by Elsa Nielsen and published by CRC Press. This book was released on 2008-02-21 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk