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Human Toxicology Of Pesticides
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Book Synopsis Human Toxicology of Pesticides by : Fina P. Kaloyanova
Download or read book Human Toxicology of Pesticides written by Fina P. Kaloyanova and published by CRC Press. This book was released on 2019-06-04 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1991, this book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.
Book Synopsis Intentional Human Dosing Studies for EPA Regulatory Purposes by : National Research Council
Download or read book Intentional Human Dosing Studies for EPA Regulatory Purposes written by National Research Council and published by National Academies Press. This book was released on 2004-06-04 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The EPA commissioned The National Academies to provide advice on the vexing question of whether and, if so, under what circumstances EPA should accept and consider intentional human dosing studies conducted by companies or other sources outside the agency (so-called third parties) to gather evidence relating to the risks of a chemical or the conditions under which exposure to it could be judged safe. This report recommends that such studies be conducted and used for regulatory purposes only if all of several strict conditions are met, including the following: The study is necessary and scientifically valid, meaning that it addresses an important regulatory question that can't be answered with animal studies or nondosing human studies; The societal benefits of the study outweigh any anticipated risks to participants. At no time, even when benefits beyond improved regulation exist, can a human dosing study be justified that is anticipated to cause lasting harm to study participants; and All recognized ethical standards and procedures for protecting the interests of study participants are observed. In addition, EPA should establish a Human Studies Review Board (HSRB) to evaluate all human dosing studiesâ€"both at the beginning and upon completion of the experimentsâ€"if they are carried out with the intent of affecting the agency's policy-making.
Book Synopsis Pesticides in the Modern World by : Margarita Stoytcheva
Download or read book Pesticides in the Modern World written by Margarita Stoytcheva and published by BoD – Books on Demand. This book was released on 2011-10-05 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a compilation of 29 chapters focused on: pesticides and food production, environmental effects of pesticides, and pesticides mobility, transport and fate. The first book section addresses the benefits of the pest control for crop protection and food supply increasing, and the associated risks of food contamination. The second book section is dedicated to the effects of pesticides on the non-target organisms and the environment such as: effects involving pollinators, effects on nutrient cycling in ecosystems, effects on soil erosion, structure and fertility, effects on water quality, and pesticides resistance development. The third book section furnishes numerous data contributing to the better understanding of the pesticides mobility, transport and fate. The addressed in this book issues should attract the public concern to support rational decisions to pesticides use.
Book Synopsis Human Toxicology of Pesticides by : Fina P. Kaloyanova
Download or read book Human Toxicology of Pesticides written by Fina P. Kaloyanova and published by CRC Press. This book was released on 1991-10-07 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.
Book Synopsis Pesticides in the Diets of Infants and Children by : National Research Council
Download or read book Pesticides in the Diets of Infants and Children written by National Research Council and published by National Academies Press. This book was released on 1993-02-01 with total page 402 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.
Book Synopsis Pesticide Toxicology by : Eugenia Gallardo
Download or read book Pesticide Toxicology written by Eugenia Gallardo and published by . This book was released on 2022 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores practical procedures on the identification and quantification of pesticides in a variety of samples. Chapters guide the reader through methods and protocols for the extraction of pesticides from biological and non-biological samples, pitfalls in dosing techniques and structures identification, and also provide an overview of the problems that these pesticides cause in human populations. As part of the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of reagents and materials, step-by-step guides and reproducible lab protocols, as well as valuable tips on addressing common problems and avoiding known pitfalls. Authoritative and practical, Pesticide Toxicology is an ideal reference for academia, analysts, toxicologists, environmentalists, and health and industry professionals aiming to understand the associated risks and to limit the use of these substances and minimize their potential damage to human health and the environment.
Book Synopsis Pesticides and Human Health by : W.H. Hallenbeck
Download or read book Pesticides and Human Health written by W.H. Hallenbeck and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impetus for this book came from numerous requests by public and private agencies and citizens for information regarding the human health effects of pes ticide exposures. We have tried to compile a relatively complete, concise sum mary of the acute and chronic health effects and the toxicology of pesticides in a format that provides quick and easy access. This book was written to address the needs of the following groups: medical and public health professionals, tox icologists, environmentalists, industrial hygienists, regulators, producers and users of pesticides, public interest advocates, and the legal profession. Acknowledgments We are indebted to Mr. Christopher J. Wiant, Chief of the Environmental Chemistry Section of the Illinois Department of Public Health. The financial support provided by his office was essential in producing this book. We are also indebted to Dr. Charles Benbrook, former staff member, and Representative George E. Brown, Chairman of the Subcommittee on Depart ment Operations, Research and Foreign Agriculture of the Committee on Agri culture, United States House of Representatives, for their guidance in obtain ing pesticide toxicity data. In the Freedom of Information Office, Office of Pesticide Programs of the United States Environmental Protection Agency, the patience and assistance of Therese Murtagh and Virginia Salzman in obtaining documents are appreciated. Of the numerous individuals who participated in the production of this book, the following merit special recognition for the quality of their research, editing, and critical skills: Mark Loafman, Sue Ramirez, Steve Smith, Sally Burns, and Denise Steurer.
Book Synopsis Toxicology of Pesticides by : Lucio G. Costa
Download or read book Toxicology of Pesticides written by Lucio G. Costa and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: The protection of human health and food and fiber resources against the ravages of pests of many sorts is a continuous struggle by all people in the world. The use of chemical pesticides as an aid in this struggle is now also global. These chemicals are deliberately added to the environment for the purpose of killing or injuring some form of life. Because pesticides are generally less selectively toxic than would be desired, non-target species, including humans, must be protected from injury by these chemicals. This can only be achieved by thorough understanding of the comparative toxicology of these compounds, and by minimizing human (and other desirable species) exposure. The latter can only be achieved by sound regulatory policies that utilize scientific principles and data, properly tempered by both gaps in that data and sociologic and economic considerations. This book contains the proceedings of the NATO Advanced Study Institute on "Toxicology of Pesticides: Experimental, Clinical and Regulatory Perspectives" held in Riva del Garda on October 6-15, 1986. This NATO-ASI has been promoted by the School of Public Health and Community Medicine, University of Washington at Seattle, by the Institute of Pharmacological Sciences, University of Milano and by the Giovanni Lorenzini Foundation, and has been sponsored by both the Society of Toxicology (USA) and the Italian Society of Toxicology.
Book Synopsis Hayes' Handbook of Pesticide Toxicology by :
Download or read book Hayes' Handbook of Pesticide Toxicology written by and published by Academic Press. This book was released on 2010-02-15 with total page 2407 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Handbook of Pesticide Toxicology is a comprehensive, two-volume reference guide to the properties, effects, and regulation of pesticides that provides the latest and most complete information to researchers investigating the environmental, agricultural, veterinary, and human-health impacts of pesticide use. Written by international experts from academia, government, and the private sector, the Handbook of Pesticide Toxicology is an in-depth examination of critical issues related to the need for, use of, and nature of chemicals used in modern pest management. This updated 3e carries on the book’s tradition of serving as the definitive reference on pesticide toxicology and recognizes the seminal contribution of Wayland J. Hayes, Jr., co-Editor of the first edition. Feature: Presents a comprehensive look at all aspects of pesticide toxicology in one reference work. Benefit: Saves researchers time in quickly accessing the very latest definitive details on toxicity of specific pesticides as opposed to searching through thousands of journal articles. Feature: Clear exposition of hazard identification and dose response relationships in each chapter featuring pesticide agents and actions Benefit: Connects the experimental laboratory results to real-life applications in human health, animal health and the environment. Feature: All major classes of pesticide considered. Benefit: Provides relevance to a wider variety of researchers who are conducting comparative work in pesticides or their health impacts. Feature: Different routes of exposure critically evaluated. Benefit: Connects the loop between exposure and harmful affects to those who are researching the affects of pesticides on humans or wildlife.
Book Synopsis Pesticide Toxicology and International Regulation by : Timothy T. Marrs
Download or read book Pesticide Toxicology and International Regulation written by Timothy T. Marrs and published by John Wiley & Sons. This book was released on 2004-04-21 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together key features of the toxicology and occupational hazards of pesticides and the way their use is regulated in the main trading regions of the world. There are chapters on each of the main groups of insecticides, namely organochlorines, anticholinesterases and pyrethrins and pyrethroids. The book also covers fungicides and herbicides, as well as more specialised agents such as microbial pesticides. The risks and hazards to humans are considered, both occupational and through the consumption of contaminated foodstuffs. Additionally, clinical aspects of pesticide poisoning are discussed. The possibility of harm from pesticide exposure has led to the development of national and international regulations governing the application of pesticides. The book describes the regulatory systems in three major economic areas: the North American Free Trade Area (USA, Canada and Mexico), the European Union and Japan. This book should be of interest to all individuals working on the development and application of pesticides anywhere in the world. All those involved in the manufacture, regulation and toxicology of pesticides should also benefit from reading this book.
Book Synopsis Mode of Action, Metabolism and Toxicology by : S. Matsunaka
Download or read book Mode of Action, Metabolism and Toxicology written by S. Matsunaka and published by Elsevier. This book was released on 2013-10-22 with total page 582 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pesticide Chemistry: Human Welfare and the Environment, Volume 3: Mode of Action, Metabolism and Toxicology covers the proceeding of the Fifth International Congress of Pesticide Chemistry. This book is organized into three parts that tackle relevant issues regarding the use of pesticide. The opening part tackles topics relevant to the biochemistry of pests and mode of action of pesticides, such as influence of chlorinated and parathyroid insecticide on cellular calcium regulatory mechanisms; behavioral and lethal actions of amidines on invertebrates; and insect chitin synthetase as biochemical probe for insecticidal compounds. The second part encompasses metabolism and degradation of pesticides and xenobiotics and includes topics on propesticides; selective toxicity conferred by activation; and comparative biochemistry of animal, plant, and microorganism oxidases. The last part covers the toxicology of pesticides and xenobiotics, including the role of biochemical studies in modern toxicological assessment of pesticides; neurophysiological and behavioral assessment of pesticide toxicity; and genetic toxicology applied to the assessment of mutagenic, carcinogenic, and teratogenic action of pesticides and related compounds. This book will be of great interest to chemists, biologists, botanists, and entomologists or professionals whose line of work involves the use of pesticides and who are concerned with pesticide side-effects to the users and the environment.
Book Synopsis Pesticide Residues in Food and Drinking Water by : Denis Hamilton
Download or read book Pesticide Residues in Food and Drinking Water written by Denis Hamilton and published by John Wiley & Sons. This book was released on 2004-03-26 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores human exposure and consumer risk assessment in response to issues surrounding pesticide residues in food and drinking water. All the three main areas of consumer risk assessment including human toxicology, pesticide residue chemistry and dietary consumption are brought together and discussed. Includes the broader picture - the environmental fate of pesticides Takes an international approach with contributors from the European Union, USA and Australia Highlights the increasing concerns over food safety and the risks to humans
Book Synopsis Environmental Toxicology of Pesticides by : Matsumura
Download or read book Environmental Toxicology of Pesticides written by Matsumura and published by Elsevier. This book was released on 2012-12-02 with total page 637 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Toxicology of Pesticides provides an overview of the state of knowledge in the major pesticidal subject areas and describes the efforts and approaches underway in solving or understanding these problems. The book emerged from the United States-Japan seminar on ""Environmental Toxicology of Pesticides"" held in Oiso, Japan, in October 1971. The purpose of the seminar was to discuss and exchange ideas and technology on the problems associated with pesticidal contamination in these two countries. The book is organized into eight parts. Part I reviews pesticide use and contamination levels in Japan, the United States, and Britain. Part II examines the environmental impact of mercury. Part III presents studies on chlorinated hydrocarbon pesticides. Part IV examines the effects of fungicides, herbicides, organophosphates, and carbamates. Part V deals with the microbial degradation of pesticides. Part VI examines the photodecomposition of pesticides. Part VII investigates the biological effects of pesticides on wildlife. Part VIII deals with the development of new pesticides.
Book Synopsis Human Toxicology of Pesticides by : Fina P. Kaloyanova
Download or read book Human Toxicology of Pesticides written by Fina P. Kaloyanova and published by CRC Press. This book was released on 2019-06-04 with total page 209 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1991, this book conducts a systematic analysis of existing information regarding the toxicological effects of pesticides on humans. The book identifies the negative health effects related to exposure to pesticides and the biological changes required to undertake biological monitoring. The book also discusses the importance and magnitude of the problem for different kinds of pesticide applications in different parts of the world, explains the toxicodynamics and clinical picture of acute and chronic intoxications resulting from exposure to different groups of pesticides and selected individual substances, and evaluates existing methods and limitations for assessing human exposure to pesticides. Pesticide manufacturers, occupational health professionals, epidemiologists, environmentalists, government agencies and others concerned with the effects of pesticides on human populations should consider this book essential reading.
Book Synopsis Toxicology of Organophosphate and Carbamate Compounds by : Ramesh C. Gupta
Download or read book Toxicology of Organophosphate and Carbamate Compounds written by Ramesh C. Gupta and published by Academic Press. This book was released on 2011-04-28 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into in-depth cholinergic and noncholinergic mechanisms of toxicity Describes recent advancements in cholinesterases, paraoxonases, carboxylesterases, oxidative stress, endocrine disruption, cardiac and pulmonary toxicity, and carcinogenesis Provides in vitro and in vivo models for neurotoxicity testing Integrates knowledge of studies in lab animals and humans Offers risk/safety assessment and national/international guidelines for permissible levels of pesticide residues Describes management of Anticholinesterase poisoning in humans
Book Synopsis Pesticides and Human Health by : W.H. Hallenbeck
Download or read book Pesticides and Human Health written by W.H. Hallenbeck and published by Springer. This book was released on 1984-12-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impetus for this book came from numerous requests by public and private agencies and citizens for information regarding the human health effects of pes ticide exposures. We have tried to compile a relatively complete, concise sum mary of the acute and chronic health effects and the toxicology of pesticides in a format that provides quick and easy access. This book was written to address the needs of the following groups: medical and public health professionals, tox icologists, environmentalists, industrial hygienists, regulators, producers and users of pesticides, public interest advocates, and the legal profession. Acknowledgments We are indebted to Mr. Christopher J. Wiant, Chief of the Environmental Chemistry Section of the Illinois Department of Public Health. The financial support provided by his office was essential in producing this book. We are also indebted to Dr. Charles Benbrook, former staff member, and Representative George E. Brown, Chairman of the Subcommittee on Depart ment Operations, Research and Foreign Agriculture of the Committee on Agri culture, United States House of Representatives, for their guidance in obtain ing pesticide toxicity data. In the Freedom of Information Office, Office of Pesticide Programs of the United States Environmental Protection Agency, the patience and assistance of Therese Murtagh and Virginia Salzman in obtaining documents are appreciated. Of the numerous individuals who participated in the production of this book, the following merit special recognition for the quality of their research, editing, and critical skills: Mark Loafman, Sue Ramirez, Steve Smith, Sally Burns, and Denise Steurer.
Book Synopsis Pesticide Toxicology and Risk Assessment by : Muneeb U. Rehman
Download or read book Pesticide Toxicology and Risk Assessment written by Muneeb U. Rehman and published by CRC Press. This book was released on 2024-05-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the emergence of new pesticide combinations and application methods, assessing their potential risks to non-target organisms and human well-being becomes paramount. Pesticide Toxicology and Risk Assessment focuses on the need and strategies for safe and efficient use of pesticides. It offers insights from toxicogenomics, enabling an understanding of the genetic and epigenetic factors influencing human susceptibility to chemical toxicity, thereby quantifying their impacts. This book underscores the significance of risk assessment methodologies considering real-time variables influencing pesticide exposure to the environment and humans. It provides comprehensive details about models designed to evaluate risks across a spectrum of scenarios, from worst-case to real-time situations, while outlining strategies to mitigate these risks proactively. Furthermore, this book delves into the critical need for conducting field studies, particularly in addressing innovative combinations and application techniques. Key Features: • Covers toxicogenomic insights, delving into genetic and epigenetic impacts on human susceptibility to chemical toxicity • Provides insight into necessary field studies for new pesticide approaches • Aids pesticide manufacturers with risk assessment and effective formulation insights As an aid for regulatory bodies, the book facilitates the evaluation of risks linked to both established and innovative pesticides, promoting informed decisions on usage by integrating risk reduction approaches. Simultaneously, it serves as a valuable guide for pesticide manufacturers, offering insights into using risk assessment tools to develop secure and effective pesticide blends. This guidance expedites the introduction of novel pesticides that are efficient and safe for various applications.
