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Author :
Publisher :
ISBN 13 : 9781461402558
Total Pages : 248 pages
Book Rating : 4.4/5 (25 download)
Download or read book Human Cell Transformation written by and published by . This book was released on 2011-09-09 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Johng S. Rhim
Publisher : Springer Nature
ISBN 13 : 3030222543
Total Pages : 246 pages
Book Rating : 4.0/5 (32 download)
Download or read book Human Cell Transformation written by Johng S. Rhim and published by Springer Nature. This book was released on 2019-10-01 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part contributed volume, part proceedings, discusses state-of-the-art advances on human cell transformation in cell models for the study of cancer and aging. Several of the chapters are from the Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging conference that was held in June 2018 at McGill University. The authors represent international expertise on a wide variety of topics ranging from different types of cancer (prostate, bone, breast, etc.) to tumor microenvironment, tumor progression, homogeneity, and possible therapies and treatments.
Author : Johng S. Rhim
Publisher : Springer Science & Business Media
ISBN 13 : 1461402549
Total Pages : 239 pages
Book Rating : 4.4/5 (614 download)
Download or read book Human Cell Transformation written by Johng S. Rhim and published by Springer Science & Business Media. This book was released on 2011-09-15 with total page 239 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhim and Kremer’s state-of-the-art volume on Human Cell Transformation: Role of Stem Cells and the Microenvironment highlights the latest findings on the current state of human cell transformation model systems and provides the insight into the molecular and cellular changes involved in the conversion of normal cells to neoplastic cells. Chapters cover all recently developed novel human cell models. In addition, the rapidly growing fields of knowledge regarding not only stem cells in cancer progression, but also the role of the microenvironments in human carcinogenesis are discussed. A wealth of topics is presented including: · Derivation of epithelial, fibroblastic, and hematopoietic in vitro model systems · Oncogenes · Tumor suppressor genes · Viral transformation · In vitro model systems for viral, chemical and radiation carcinogenesis · Cell aging · The multistep nature of human carcinogenesis · The role of stem cells and the microenvironment in tumorigenesis · The genes involved in multistep carcinogenesis Unique in both scope and focus – devoted solely to human cell transformation systems – Human Cell Transformation: Role of Stem Cells and the Microenvironment provides unparalleled, in-depth coverage for cancer researchers, cell and molecular biologists, hematologists, virologists, and workers in related fields. Essential reading for everyone who needs to be kept up-to-date in this fast-paced area! Features ؠ Multistep models ؠ Breast cancer/Stem cells ؠ Prostate cancer/Stem cells ؠ Multistep / Genes
Author : Robert C. Bast, Jr.
Publisher : John Wiley & Sons
ISBN 13 : 111900084X
Total Pages : 2008 pages
Book Rating : 4.1/5 (19 download)
Download or read book Holland-Frei Cancer Medicine written by Robert C. Bast, Jr. and published by John Wiley & Sons. This book was released on 2017-03-10 with total page 2008 pages. Available in PDF, EPUB and Kindle. Book excerpt: Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates
Author : Johng S. Rhim
Publisher : Springer
ISBN 13 : 9781493941643
Total Pages : 224 pages
Book Rating : 4.9/5 (416 download)
Download or read book Human Cell Transformation written by Johng S. Rhim and published by Springer. This book was released on 2016-08-23 with total page 224 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rhim and Kremer’s state-of-the-art volume on Human Cell Transformation: Role of Stem Cells and the Microenvironment highlights the latest findings on the current state of human cell transformation model systems and provides the insight into the molecular and cellular changes involved in the conversion of normal cells to neoplastic cells. Chapters cover all recently developed novel human cell models. In addition, the rapidly growing fields of knowledge regarding not only stem cells in cancer progression, but also the role of the microenvironments in human carcinogenesis are discussed. A wealth of topics is presented including: · Derivation of epithelial, fibroblastic, and hematopoietic in vitro model systems · Oncogenes · Tumor suppressor genes · Viral transformation · In vitro model systems for viral, chemical and radiation carcinogenesis · Cell aging · The multistep nature of human carcinogenesis · The role of stem cells and the microenvironment in tumorigenesis · The genes involved in multistep carcinogenesis Unique in both scope and focus – devoted solely to human cell transformation systems – Human Cell Transformation: Role of Stem Cells and the Microenvironment provides unparalleled, in-depth coverage for cancer researchers, cell and molecular biologists, hematologists, virologists, and workers in related fields. Essential reading for everyone who needs to be kept up-to-date in this fast-paced area! Features ؠ Multistep models ؠ Breast cancer/Stem cells ؠ Prostate cancer/Stem cells ؠ Multistep / Genes
Author : Bruce Alberts
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of The Cell written by Bruce Alberts and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alecsandru Ioan Baba
Publisher :
ISBN 13 : 9789732714577
Total Pages : 787 pages
Book Rating : 4.7/5 (145 download)
Download or read book Comparative Oncology written by Alecsandru Ioan Baba and published by . This book was released on 2007 with total page 787 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Johng S. Rhim
Publisher : Springer Science & Business Media
ISBN 13 : 1461204119
Total Pages : 405 pages
Book Rating : 4.4/5 (612 download)
Download or read book Neoplastic Transformation in Human Cell Culture written by Johng S. Rhim and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: The role of carcinogenic agents in the deveolopment of human cancers is now being defined using a variety of human cells as experi mental model systems. A workshop on "neoplastic transformation in human cell systems in vitro: mechanisms of carcinogenesis" was held at the Georgetown University Medical Center, Washington, DC, on April 25-26, 1991. The aims of the workshop were to present the state-of-the art in the transformation of human cells in culture, as well as to provide insight into the molecular and cellular changes involved in the conver sion of normal cells to a neoplastic state of growth. The following topics were closely related to the theme of the workshops: 1. Derivation of in vitro model systems (epithelial, fibroblastic, and hematopoietic). 2. Factors modulating cellular transformation. 3. Usefulness of defined in vitro model systems for viral, chemical, and radiation carcinogenesis. 4. Multistep nature of human cell carcinogenesis. 5. Role of activated and suppressor oncogenes in neoplastic trans formation. The workshop was organized by J. S. Rhim and A. Dritschilo (cochairmen), G. Jay, J. little, M. McCormick, R Tennant, and R R Weischelbaum. There were 32 speakers, 30 poster presentations, and about 190 participants.
Author : J. Celis
Publisher : Springer Science & Business Media
ISBN 13 : 1468450093
Total Pages : 321 pages
Book Rating : 4.4/5 (684 download)
Download or read book Cell Transformation written by J. Celis and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kenneth Helme Chadwick
Publisher : CRC Press
ISBN 13 :
Total Pages : 436 pages
Book Rating : 4.3/5 (91 download)
Download or read book Cell Transformation Systems Relevant to Radiation Induced Cancer in Man, Proceedings of a Workshop Jointly Organised by the Nuclear Energy Board of Ireland, the United States Department of Energy and the Commission of the European Communities, Held in Du written by Kenneth Helme Chadwick and published by CRC Press. This book was released on 1989 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The transformation of mammalian cells in vitro provides quantitative and qualitative information on the processes by which physical and chemical agents induce malignancy. Recently, there has been considerable progress on the developmnent of new cell transformation systems and the role of oncogenes in cell transformation. An International Workshop held during April 1989 in Dublin encouraged collaborative interactions between the scientists working in this field and provided a forum for critical review of current research results. Cell Transformation and Radiation-induced Cancer is a record of the papers presented at the Workshop. It includes work which focuses on the potential of emerging human cell transformation systems and their relevance to radiation carcinogenesis, and on the role and interplay of oncogenes, retroviruses and radiation in cell transformation. Particular emphasis is placed on the influence of such variables as radiation quality, dose and dose rate, promoters and suppressors and cell types on in vitro cell transformation. Also considered are the implications of the results from cell transformation studies for radiation-induced cancer in man and for radiological protection. This book will be of interest to molecular biologists, medical physicists and cancer specialists who require a comprehensive account of the latest work on cell transformation and radiation-induced cancer.
Author : George Milo
Publisher : CRC Press
ISBN 13 : 1351355988
Total Pages : 326 pages
Book Rating : 4.3/5 (513 download)
Download or read book Transformation of Human Epithelial Cells (1992) written by George Milo and published by CRC Press. This book was released on 2017-11-22 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: * Offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites] * Examines in vitro cellular aging and the role of immortalization * Presents stages of control of expression and the factors influencing growth and differentiation
Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309170427
Total Pages : 112 pages
Book Rating : 4.3/5 (91 download)
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Author : Siddhartha Mukherjee
Publisher : Simon and Schuster
ISBN 13 : 1982117370
Total Pages : 496 pages
Book Rating : 4.9/5 (821 download)
Download or read book The Song of the Cell written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2022-10-25 with total page 496 pages. Available in PDF, EPUB and Kindle. Book excerpt: Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences and the 2023 Chautauqua Prize! Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more! In The Song of the Cell, the extraordinary author of the Pulitzer Prize–winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” (Oprah Daily). Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christened them “cells.” The discovery of cells—and the reframing of the human body as a cellular ecosystem—announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia—all could be reconceived as the results of cells, or systems of cells, functioning abnormally. And all could be perceived as loci of cellular therapies. Filled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate—a masterpiece on what it means to be human. “In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” (The New Yorker).
Download or read book Cellular Transforming Genes written by and published by . This book was released on 1986 with total page 4 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : George E. Milo
Publisher : CRC Press
ISBN 13 : 9780849349560
Total Pages : 306 pages
Book Rating : 4.3/5 (495 download)
Download or read book Transformation of Human Diploid Fibroblasts written by George E. Milo and published by CRC Press. This book was released on 1990-05-15 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive publication draws together the important aspects of carcinogen-cell interaction. This interesting work describes the regulation of normal cell proliferation, cellular responses to carcinogen damage, the biologic consequences of cellular DNA modification, the structural and genomic changes resulting from carcinogen insult, and the possible involvement of such changes in the conversion of normal human fibroblasts to malignant cells. It presents current reviews with up-to-date literature references and provides critical information from leading investigators that is essential in understanding the biology of human cell transformation. This volume is especially useful to advanced students in genetic toxicology, molecular biologists, and all who are interested in the molecular and macromolecular changes in human cells leading to neoplasia.
Author : Ajit Varki
Publisher : CSHL Press
ISBN 13 : 9780879696818
Total Pages : 694 pages
Book Rating : 4.6/5 (968 download)
Download or read book Essentials of Glycobiology written by Ajit Varki and published by CSHL Press. This book was released on 1999 with total page 694 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author : Ivan Cameron
Publisher : Elsevier
ISBN 13 : 0323162967
Total Pages : 452 pages
Book Rating : 4.3/5 (231 download)
Download or read book The Transformed Cell written by Ivan Cameron and published by Elsevier. This book was released on 1981-01-01 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Transformed Cell deals with many of the differences that may exist between transformed cells and their normal counterparts. Topics covered range from malignancy and the cell surface to cell cycle regulation in normal and transformed cells; phenotypic expression of malignant transformation and its relationship to energy metabolism; and virus-induced transformation. The involvement of cyclic nucleotides in transformation is also discussed, together with intracellular pH and growth control in eukaryotic cells. This book is comprised of 12 chapters and begins with a brief description of terminology and basic concepts relating to cancer cells, as well as some comments on tumorigenicity and cell transformation. The next two chapters explore the evidence for and against the possible correlation of in vivo tumorigenicity to in vitro changes in the cytoskeletal system; anchorage-dependent growth; plasminogen activator production; agglutinability by lectins; and cell surface and plasma membrane properties. The regulation of cell proliferation and the relationships between ion movement and energy metabolism in normal and transformed cells are then examined, along with the transformation of normal cells by infection with new genetic material from tumor viruses. The remaining chapters focus on selected cellular properties that have been purported to differ between the normal and transformed cell, with particular reference to cyclic nucleotides; polyamine metabolism; cell viscosity; mobility of cellular water; intracellular pH; and element concentration. This monograph will be of interest to biologists and medical practitioners devoted to understanding cancer cell biology and cancer therapy.
