Homology Effects

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Homology Effects

Author :
Publisher : Elsevier
ISBN 13 : 0080490328
Total Pages : 565 pages
Book Rating : 4.0/5 (84 download)

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Book Synopsis Homology Effects by :

Download or read book Homology Effects written by and published by Elsevier. This book was released on 2002-04-02 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Homology Effects offers contributions from an international panel of researchers whose aim has been both to introduce newcomers to the field of homology effects, and to bring colleagues up to date. Topic coverage includes dosage compensation, X-inactivation, imprinting, paramutation, homology-dependent gene silencing, transvection, pairing-sensitive silencing, nuclear organization of chromosomes, DNA repair, quelling, RIP, RNAi and antisense biology, homology effects in ciliates, prion biology, and a discourse on the evolution of gene duplications. Advances in Genetics presents an eclectic mix of articles of use to all human and molecular geneticists. They are written and edited by recognized leaders in the field and make this an essential series of books for anyone in the genetics field. Homology, the examination of similarity due to shared common ancestry, encompasses a fascinating class of phenomena in mammals, plants, insects, ciliates, nematodes, fungi, and bacteria. Homology effects concern processes that recognize homology at the level of DNA and/or RNA, as well as at the level of protein. Their collective history begins at the turn of the century and includes some of the most puzzling and extraordinary observations in biology. The volume covers phenomena that have often been considered unusual, exceptional to the rule, and "out of the ordinary" and, therefore, not for general study. However, it is now becoming clear that taken together, these phenomena represent a class of regulatory mechanisms that are widespread, as well as exceptionally powerful.

THE EFFECTS OF SEQUENCE HOMOLOGY ON TRANSFORMATION OF MOUSE CELLS BY SV40 DNA.

Author : REX LESLIE CHISHOLM
Publisher :
ISBN 13 :
Total Pages : 242 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis THE EFFECTS OF SEQUENCE HOMOLOGY ON TRANSFORMATION OF MOUSE CELLS BY SV40 DNA. by : REX LESLIE CHISHOLM

Download or read book THE EFFECTS OF SEQUENCE HOMOLOGY ON TRANSFORMATION OF MOUSE CELLS BY SV40 DNA. written by REX LESLIE CHISHOLM and published by . This book was released on 1980 with total page 242 pages. Available in PDF, EPUB and Kindle. Book excerpt: (pRC105) lacking the mouse DNA, and about 1.4 times that of SV40 DNA. pRC105 DNA had only about 40% the transformation efficiency of uncloned SV40 DNA.

Mipham's Dialectics and the Debates on Emptiness

Author : Karma Phuntsho
Publisher : Routledge
ISBN 13 : 1134262477
Total Pages : 321 pages
Book Rating : 4.1/5 (342 download)

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Book Synopsis Mipham's Dialectics and the Debates on Emptiness by : Karma Phuntsho

Download or read book Mipham's Dialectics and the Debates on Emptiness written by Karma Phuntsho and published by Routledge. This book was released on 2005-03-31 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is an introduction to the Buddhist philosophy of Emptiness Useful for scholars of Tibetan studies and Buddhist philosophy Explores the theories of Emptiness in an easy narrative style This is a compelling account of Emptiness

Homology

Author : Brian K. Hall
Publisher : Elsevier
ISBN 13 : 0080574300
Total Pages : 500 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Homology by : Brian K. Hall

Download or read book Homology written by Brian K. Hall and published by Elsevier. This book was released on 2013-10-22 with total page 500 pages. Available in PDF, EPUB and Kindle. Book excerpt: The application of homology varies depending on the data being examined. This volume represents a state-of-the-art treatment of the different applications of this unifying concept. Chapters deal with homology on all levels, from molecules to behavior, and are authored by leading contributors to systematics, natural history, and evolutionary, developmental, and comparative biology. This paperback reprint of the original hardbound edition continues to commemorate the 150th anniversary of Sir Richard Owen's seminal paper distinguishing homology from analogy. Commemoration of the 150th anniversary of Sir Richard Owen's seminal paper distinguishing homology from analogy Contributors who are renowned leaders in comparative biology Coverage that is both comprehensive and interdisciplinary

Medicine and food homology: Emerging tool and methodology for separation and analysis of the bioactive factors

Author : Haining Zhuang
Publisher : Frontiers Media SA
ISBN 13 : 2832537936
Total Pages : 135 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Medicine and food homology: Emerging tool and methodology for separation and analysis of the bioactive factors by : Haining Zhuang

Download or read book Medicine and food homology: Emerging tool and methodology for separation and analysis of the bioactive factors written by Haining Zhuang and published by Frontiers Media SA. This book was released on 2023-11-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Homology

Author : Gregory R. Bock
Publisher : John Wiley & Sons
ISBN 13 : 047051566X
Total Pages : 266 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Homology by : Gregory R. Bock

Download or read book Homology written by Gregory R. Bock and published by John Wiley & Sons. This book was released on 2008-04-30 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away from comparative morphology to ideas based on developmental pathways have tended to founder on the fact that developmental pathways evolve and that similar cells or tissues or structures in animals will often have different developmental origins. The use of information about conserved molecules in seemingly conserved developmental processes has also proven controversial. In molecular biology, the use of the term 'homology' has given rise to more debate, although here the issue seems to involve primarily the criteria for assessing whether parts of genes are the same because of shared descent or for other reasons. The contributions to the book explore these topics systematically. There are chapters on the historical development of the concept of homology and its use in population studies. Other chapters deal with issues of homology in morphological and developmental studies, in behavioural studies, and especially in studies at the level of molecular genetics.

Grid Homology for Knots and Links

Author : Peter S. Ozsváth
Publisher : American Mathematical Soc.
ISBN 13 : 1470417375
Total Pages : 410 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Grid Homology for Knots and Links by : Peter S. Ozsváth

Download or read book Grid Homology for Knots and Links written by Peter S. Ozsváth and published by American Mathematical Soc.. This book was released on 2015-12-04 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: Knot theory is a classical area of low-dimensional topology, directly connected with the theory of three-manifolds and smooth four-manifold topology. In recent years, the subject has undergone transformative changes thanks to its connections with a number of other mathematical disciplines, including gauge theory; representation theory and categorification; contact geometry; and the theory of pseudo-holomorphic curves. Starting from the combinatorial point of view on knots using their grid diagrams, this book serves as an introduction to knot theory, specifically as it relates to some of the above developments. After a brief overview of the background material in the subject, the book gives a self-contained treatment of knot Floer homology from the point of view of grid diagrams. Applications include computations of the unknotting number and slice genus of torus knots (asked first in the 1960s and settled in the 1990s), and tools to study variants of knot theory in the presence of a contact structure. Additional topics are presented to prepare readers for further study in holomorphic methods in low-dimensional topology, especially Heegaard Floer homology. The book could serve as a textbook for an advanced undergraduate or part of a graduate course in knot theory. Standard background material is sketched in the text and the appendices.

Homology, Genes, and Evolutionary Innovation

Author : Günter P. Wagner
Publisher : Princeton University Press
ISBN 13 : 0691180679
Total Pages : 494 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis Homology, Genes, and Evolutionary Innovation by : Günter P. Wagner

Download or read book Homology, Genes, and Evolutionary Innovation written by Günter P. Wagner and published by Princeton University Press. This book was released on 2018-07-10 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.

Research Frontiers in Aging and Cancer

Author :
Publisher :
ISBN 13 :
Total Pages : 324 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Research Frontiers in Aging and Cancer by :

Download or read book Research Frontiers in Aging and Cancer written by and published by . This book was released on 1982 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Light Elements in the Universe (IAU S268)

Author : International Astronomical Union. Symposium
Publisher : Cambridge University Press
ISBN 13 : 9780521765060
Total Pages : 528 pages
Book Rating : 4.7/5 (65 download)

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Book Synopsis Light Elements in the Universe (IAU S268) by : International Astronomical Union. Symposium

Download or read book Light Elements in the Universe (IAU S268) written by International Astronomical Union. Symposium and published by Cambridge University Press. This book was released on 2010-05-13 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: IAU Symposium 268 presents an overview of the most recent observational and theoretical research on the formation and evolution of light elements in the Universe: H, He, Li, Be, B, and their isotopes. Astrophysicists from a variety of subfields discuss recent developments that will improve our understanding of the light elements and provide important clues to stellar and galactic evolution, Big Bang nucleosynthesis, and cosmology. Striking observational progress has been achieved recently through the advent of next generation ground- and space-based telescopes, such as the cosmic microwave background experiments that allow the accurate determination of the baryon density of the Universe. New theoretical breakthroughs in describing stellar interiors and the chemical evolution of complex systems and the remaining challenges in this field are also addressed. This critical review is a useful resource for all those interested in the chemical evolution of the Universe.

Links Between Recombination and Replication

Author : Proceedings of the National Academy of Sciences
Publisher : National Academies Press
ISBN 13 : 030907424X
Total Pages : 303 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Links Between Recombination and Replication by : Proceedings of the National Academy of Sciences

Download or read book Links Between Recombination and Replication written by Proceedings of the National Academy of Sciences and published by National Academies Press. This book was released on 2002-09-18 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a sea change in how we view genetic recombination. When germ cells are produced in higher organisms, genetic recombination assures the proper segregation of like chromosomes. In the course of that process, called meiosis, recombination not only assures segregation of one chromosome of each type to progeny germ cells, but also further shuffles the genetic deck, contributing to the unique inheritance of individuals. In a nutshell, that is the classical view of recombination. We have also known for many years that in bacteria recombination plays a role in horizontal gene transfer and in replication itself, the latter by establishing some of the replication forks that are the structural scaffolds for copying DNA. In recent years, however, we have become increasingly aware that replication, which normally starts without any help from recombination, is a vulnerable process that frequently leads to broken DNA. The enzymes of recombination play a vital role in the repair of those breaks. The recombination enzymes can function via several different pathways that mediate the repair of breaks, as well as restoration of replication forks that are stalled by other kinds of damage to DNA. Thus, to the classical view of recombination as an engine of inheritance we must add the view of recombination as a vital housekeeping function that repairs breaks suffered in the course of replication. We have also known for many years that genomic instability--including mutations, chromosomal rearrangements, and aneuploidy--is a hallmark of cancer cells. Although genomic instability has many contributing causes, including faulty replication, there are many indications that recombination, faulty or not, contributes to genome instability and cancer as well. The (Nas colloquium) Links Between Recombination and Replication: Vital Roles of Recombination was convened to broaden awareness of this evolving area of research. Papers generated by this colloquium are published here. To encourage the desired interactions of specialists, we invited some contributions that deal only with recombination or replication in addition to contributions on the central thesis of functional links between recombination and replication. To aid the nonspecialist and specialist alike, we open the set of papers with a historical overview by Michael Cox and we close the set with a commentary on the meeting and the field by Andrei Kuzminov.

Homology and Systematics

Author : Robert Scotland
Publisher : CRC Press
ISBN 13 : 1482268248
Total Pages : 226 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Homology and Systematics by : Robert Scotland

Download or read book Homology and Systematics written by Robert Scotland and published by CRC Press. This book was released on 2014-04-21 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: When looking at groups of organisms, shared characteristics (homologues) provide the raw data from which hypotheses of common ancestry may be suggested. In order to explore the relationship between homologues and particular hypotheses of common ancestry, complex matrices are devised, where homologues are coded, allowing theories of homology to be developed and tested. Practically nothing has been written about this matrix-building process, which is fundamental to our understanding of diversity and evolutionary history. This book fills the gap by discussing the ways observations are coded and the consequences for resulting hypotheses using case studies and theoretical examples.

Genome Editing and Engineering

Author : Krishnarao Appasani
Publisher : Cambridge University Press
ISBN 13 : 1107170370
Total Pages : 535 pages
Book Rating : 4.1/5 (71 download)

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Book Synopsis Genome Editing and Engineering by : Krishnarao Appasani

Download or read book Genome Editing and Engineering written by Krishnarao Appasani and published by Cambridge University Press. This book was released on 2018-08-23 with total page 535 pages. Available in PDF, EPUB and Kindle. Book excerpt: A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

Biocomputing 2016 - Proceedings Of The Pacific Symposium

Author : Russ B Altman
Publisher : World Scientific
ISBN 13 : 9814749427
Total Pages : 604 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Biocomputing 2016 - Proceedings Of The Pacific Symposium by : Russ B Altman

Download or read book Biocomputing 2016 - Proceedings Of The Pacific Symposium written by Russ B Altman and published by World Scientific. This book was released on 2015-11-19 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Pacific Symposium on Biocomputing (PSB) 2016 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2016 will be held on January 4 - 8, 2016 in Kohala Coast, Hawaii. Tutorials and workshops will be offered prior to the start of the conference.PSB 2016 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's 'hot topics.' In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

The Ecology and Evolution of Heliconius Butterflies

Author : Chris D. Jiggins
Publisher : Oxford University Press
ISBN 13 : 0192509071
Total Pages : 288 pages
Book Rating : 4.1/5 (925 download)

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Book Synopsis The Ecology and Evolution of Heliconius Butterflies by : Chris D. Jiggins

Download or read book The Ecology and Evolution of Heliconius Butterflies written by Chris D. Jiggins and published by Oxford University Press. This book was released on 2017-01-27 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Heliconius butterflies are one of the classic systems in evolutionary biology and have contributed hugely to our understanding of evolution over the last 150 years. Their dramatic radiation and remarkable mimicry has fascinated biologists since the days of Bates, Wallace, and Darwin. The Ecology and Evolution of Heliconius Butterflies is the first thorough and accessible treatment of the ecology, genetics, and behaviour of these butterflies, exploring how they offer remarkable insights into tropical biodiversity. The book starts by outlining some of the evolutionary questions that Heliconius research has helped to address, then moves on to an overview of the butterflies themselves and their ecology and behaviour before focussing on wing pattern evolution, and finally, speciation. Richly illustrated with 32 colour plates, this book makes the extensive scientific literature on Heliconius butterflies accessible to a wide audience of professional ecologists, evolutionary biologists, entomologists, and amateur collectors.

Genetic Theory and Analysis

Author : Danny E. Miller
Publisher : John Wiley & Sons
ISBN 13 : 1118086929
Total Pages : 309 pages
Book Rating : 4.1/5 (18 download)

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Book Synopsis Genetic Theory and Analysis by : Danny E. Miller

Download or read book Genetic Theory and Analysis written by Danny E. Miller and published by John Wiley & Sons. This book was released on 2023-08-29 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: GENETIC THEORY AND ANALYSIS Understand and apply what drives change of characteristic genetic traits and heredity Genetics is the study of how traits are passed from parents to their offspring and how the variation in those traits affects the development and health of the organism. Investigating how these traits affect the organism involves a diverse set of approaches and tools, including genetic screens, DNA and RNA sequencing, mapping, and methods to understand the structure and function of proteins. Thus, there is a need for a textbook that provides a broad overview of these methods. Genetic Theory and Analysis meets this need by describing key approaches and methods in genetic analysis through a historical lens. Focusing on the five basic principles underlying the field—mutation, complementation, recombination, segregation, and regulation—it identifies the full suite of tests and methodologies available to the geneticist in an age of flourishing genetic and genomic research. This second edition of the text has been updated to reflect recent advances and increase accessibility to advanced undergraduate students. Genetic Theory and Analysis, 2nd edition readers will also find: Detailed treatment of subjects including mutagenesis, meiosis, complementation, suppression, and more Updated discussion of epistasis, mosaic analysis, RNAi, genome sequencing, and more Appendices discussing model organisms, genetic fine-structure analysis, and tetrad analysis Genetic Theory and Analysis is ideal for both graduate students and advanced undergraduates undertaking courses in genetics, genetic engineering, and computational biology.

Target Discovery and Validation

Author : Alleyn T. Plowright
Publisher : John Wiley & Sons
ISBN 13 : 3527818251
Total Pages : 416 pages
Book Rating : 4.5/5 (278 download)

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Book Synopsis Target Discovery and Validation by : Alleyn T. Plowright

Download or read book Target Discovery and Validation written by Alleyn T. Plowright and published by John Wiley & Sons. This book was released on 2019-12-02 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: The modern drug developers? guide for making informed choices among the diverse target identification methods Target Discovery and Validation: Methods and Strategies for Drug Discovery offers a hands-on review of the modern technologies for drug target identification and validation. With contributions from noted industry and academic experts, the book addresses the most recent chemical, biological, and computational methods. Additionally, the book highlights techologies that are applicable to ?difficult? targets and drugs directed at multiple targets, including chemoproteomics, activity-based protein profiling, pathway mapping, genome-wide association studies, and array-based profiling. Throughout, the authors highlight a range of diverse approaches, and target validation studies reveal how these methods can support academic and drug discovery scientists in their target discovery and validation research. This resource: -Offers a guide to identifying and validating targets, a key enabling technology without which no new drug development is possible -Presents the information needed for choosing the appropriate assay method from the ever-growing range of available options -Provides practical examples from recent drug development projects, e. g. in kinase inhibitor profiling Written for medicinal chemists, pharmaceutical professionals, biochemists, biotechnology professionals, and pharmaceutical chemists, Target Discovery and Validation explores the current methods for the identification and validation of drug targets in one comrpehensive volume. It also includes numerous practical examples.