The Century of the Gene

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Publisher : Harvard University Press
ISBN 13 : 0674039432
Total Pages : 194 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis The Century of the Gene by : Evelyn Fox KELLER

Download or read book The Century of the Gene written by Evelyn Fox KELLER and published by Harvard University Press. This book was released on 2009-06-30 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: In a book that promises to change the way we think and talk about genes and genetic determinism, Evelyn Fox Keller, one of our most gifted historians and philosophers of science, provides a powerful, profound analysis of the achievements of genetics and molecular biology in the twentieth century, the century of the gene. Not just a chronicle of biology’s progress from gene to genome in one hundred years, The Century of the Gene also calls our attention to the surprising ways these advances challenge the familiar picture of the gene most of us still entertain. Keller shows us that the very successes that have stirred our imagination have also radically undermined the primacy of the gene—word and object—as the core explanatory concept of heredity and development. She argues that we need a new vocabulary that includes concepts such as robustness, fidelity, and evolvability. But more than a new vocabulary, a new awareness is absolutely crucial: that understanding the components of a system (be they individual genes, proteins, or even molecules) may tell us little about the interactions among these components. With the Human Genome Project nearing its first and most publicized goal, biologists are coming to realize that they have reached not the end of biology but the beginning of a new era. Indeed, Keller predicts that in the new century we will witness another Cambrian era, this time in new forms of biological thought rather than in new forms of biological life.

The Gene

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Author :
Publisher : Simon and Schuster
ISBN 13 : 1476733538
Total Pages : 624 pages
Book Rating : 4.4/5 (767 download)

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Book Synopsis The Gene by : Siddhartha Mukherjee

Download or read book The Gene written by Siddhartha Mukherjee and published by Simon and Schuster. This book was released on 2016-05-17 with total page 624 pages. Available in PDF, EPUB and Kindle. Book excerpt: The #1 NEW YORK TIMES Bestseller The basis for the PBS Ken Burns Documentary The Gene: An Intimate History Now includes an excerpt from Siddhartha Mukherjee’s new book Song of the Cell! From the Pulitzer Prize–winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Sid Mukherjee has the uncanny ability to bring together science, history, and the future in a way that is understandable and riveting, guiding us through both time and the mystery of life itself.” —Ken Burns “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).

Orthodoxy in Massachusetts, 1630-1650

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Author :
Publisher :
ISBN 13 : 9780674181137
Total Pages : 0 pages
Book Rating : 4.1/5 (811 download)

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Book Synopsis Orthodoxy in Massachusetts, 1630-1650 by : Perry Miller

Download or read book Orthodoxy in Massachusetts, 1630-1650 written by Perry Miller and published by . This book was released on 1933-02-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:

THE CENTURY OF THE GENE

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Author :
Publisher : Harvard University Press
ISBN 13 : 9780674008250
Total Pages : 192 pages
Book Rating : 4.0/5 (82 download)

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Book Synopsis THE CENTURY OF THE GENE by : Evelyn Fox KELLER

Download or read book THE CENTURY OF THE GENE written by Evelyn Fox KELLER and published by Harvard University Press. This book was released on 2002 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: Arguing for a new vocabulary of genetics, the author shows why the past century of gene research and molecular biology was so revolutionary and assesses the potential implications of the Human Genome Project and other biological and genetic advances.

The Genetic Structure of an Historical Population

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Publisher :
ISBN 13 :
Total Pages : 208 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis The Genetic Structure of an Historical Population by : Alan C. Swedlund

Download or read book The Genetic Structure of an Historical Population written by Alan C. Swedlund and published by . This book was released on 1971 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt:

In Pursuit of the Gene

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Publisher : Harvard University Press
ISBN 13 : 0674034910
Total Pages : 385 pages
Book Rating : 4.6/5 (74 download)

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Book Synopsis In Pursuit of the Gene by : James Schwartz

Download or read book In Pursuit of the Gene written by James Schwartz and published by Harvard University Press. This book was released on 2010-03-30 with total page 385 pages. Available in PDF, EPUB and Kindle. Book excerpt: The mystery of inheritance has captivated thinkers since antiquity, and the unlocking of this mystery—the development of classical genetics—is one of humanity’s greatest achievements. This great scientific and human drama is the story told fully and for the first time in this book. Acclaimed science writer James Schwartz presents the history of genetics through the eyes of a dozen or so central players, beginning with Charles Darwin and ending with Nobel laureate Hermann J. Muller. In tracing the emerging idea of the gene, Schwartz deconstructs many often-told stories that were meant to reflect glory on the participants and finds that the “official” version of discovery often hides a far more complex and illuminating narrative. The discovery of the structure of DNA and the more recent advances in genome science represent the culmination of one hundred years of concentrated inquiry into the nature of the gene. Schwartz’s multifaceted training as a mathematician, geneticist, and writer enables him to provide a remarkably lucid account of the development of the central ideas about heredity, and at the same time bring to life the brilliant and often eccentric individuals who shaped these ideas. In the spirit of the late Stephen Jay Gould, this book offers a thoroughly engaging story about one of the oldest and most controversial fields of scientific inquiry. It offers readers the background they need to understand the latest findings in genetics and those still to come in the search for the genetic basis of complex diseases and traits.

Who Wrote the Book of Life?

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Publisher : Stanford University Press
ISBN 13 : 9780804734172
Total Pages : 476 pages
Book Rating : 4.7/5 (341 download)

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Book Synopsis Who Wrote the Book of Life? by : Lily E. Kay

Download or read book Who Wrote the Book of Life? written by Lily E. Kay and published by Stanford University Press. This book was released on 2000 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a detailed history of one of the most important and dramatic episodes in modern science, recounted from the novel vantage point of the dawn of the information age and its impact on representations of nature, heredity, and society. Drawing on archives, published sources, and interviews, the author situates work on the genetic code (1953-70) within the history of life science, the rise of communication technosciences (cybernetics, information theory, and computers), the intersection of molecular biology with cryptanalysis and linguistics, and the social history of postwar Europe and the United States. Kay draws out the historical specificity in the process by which the central biological problem of DNA-based protein synthesis came to be metaphorically represented as an information code and a writing technology—and consequently as a “book of life.” This molecular writing and reading is part of the cultural production of the Nuclear Age, its power amplified by the centuries-old theistic resonance of the “book of life” metaphor. Yet, as the author points out, these are just metaphors: analogies, not ontologies. Necessary and productive as they have been, they have their epistemological limitations. Deploying analyses of language, cryptology, and information theory, the author persuasively argues that, technically speaking, the genetic code is not a code, DNA is not a language, and the genome is not an information system (objections voiced by experts as early as the 1950s). Thus her historical reconstruction and analyses also serve as a critique of the new genomic biopower. Genomic textuality has become a fact of life, a metaphor literalized, she claims, as human genome projects promise new levels of control over life through the meta-level of information: control of the word (the DNA sequences) and its editing and rewriting. But the author shows how the humbling limits of these scriptural metaphors also pose a challenge to the textual and material mastery of the genomic “book of life.”

Reader's Guide to the History of Science

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Author :
Publisher : Routledge
ISBN 13 : 1134262949
Total Pages : 965 pages
Book Rating : 4.1/5 (342 download)

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Book Synopsis Reader's Guide to the History of Science by : Arne Hessenbruch

Download or read book Reader's Guide to the History of Science written by Arne Hessenbruch and published by Routledge. This book was released on 2013-12-16 with total page 965 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Reader's Guide to the History of Science looks at the literature of science in some 550 entries on individuals (Einstein), institutions and disciplines (Mathematics), general themes (Romantic Science) and central concepts (Paradigm and Fact). The history of science is construed widely to include the history of medicine and technology as is reflected in the range of disciplines from which the international team of 200 contributors are drawn.

Life History Evolution

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Publisher : Sinauer Associates Incorporated
ISBN 13 : 9780878937561
Total Pages : 527 pages
Book Rating : 4.9/5 (375 download)

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Book Synopsis Life History Evolution by : Derek A. Roff

Download or read book Life History Evolution written by Derek A. Roff and published by Sinauer Associates Incorporated. This book was released on 2002 with total page 527 pages. Available in PDF, EPUB and Kindle. Book excerpt: Life History Evolution represents a synthetic approach to the understanding of the evolution of life history variation using the three types of environment (constant, stochastic, predictable) as the focus under which the theory is developed and tested. First, the author outlines a general framework for the study and analysis of life history variation, bringing together the approaches of quantitative genetic modeling and optimality analysis. Using this framework, he then discusses how life histories evolve in the three different types of environments, each of which presents unique characteristics. The theme of the book is that an understanding of evolutionary change requires analysis at both the genetic and phenotypic levels, and that the environment plays a central role in such analyses. Intended for graduate students and researchers, the book's emphasis is on assumptions and testing of models. Mathematical processes are described, but mathematical derivations are kept to a minimum. Each chapter includes a summary, and boxes provide supplementary material.

A Brief History of Genetics

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Publisher : Cambridge Scholars Publishing
ISBN 13 : 1527561305
Total Pages : 514 pages
Book Rating : 4.5/5 (275 download)

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Book Synopsis A Brief History of Genetics by : Chris Rider

Download or read book A Brief History of Genetics written by Chris Rider and published by Cambridge Scholars Publishing. This book was released on 2020-10-27 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biological inheritance, the passage of key characteristics down the generations, has always held mankind’s fascination. It is fundamental to the breeding of plants and animals with desirable traits. Genetics, the scientific study of inheritance, can be traced back to a particular set of simple but ground-breaking studies carried out 170 years ago. The awareness that numerous diseases are inherited gives this subject considerable medical importance. The progressive advances in genetics now bring us to the point where we have unravelled the entire human genome, and that of many other species. We can intervene very precisely with the genetic make-up of our agricultural crops and animals, and even ourselves. Genetics now enables us to understand cancer and develop novel protein medicines. It has also provided us with DNA fingerprinting for the solving of serious crime. This book explains for a lay readership how, where and when this powerful science emerged.

The History and Geography of Human Genes

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Publisher : Princeton University Press
ISBN 13 : 0691187266
Total Pages : 430 pages
Book Rating : 4.6/5 (911 download)

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Book Synopsis The History and Geography of Human Genes by : L L Cavalli-sforza

Download or read book The History and Geography of Human Genes written by L L Cavalli-sforza and published by Princeton University Press. This book was released on 2018-06-05 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hailed as a breakthrough in the understanding of human evolution, The History and Geography of Human Genes offers the first full-scale reconstruction of where human populations originated and the paths by which they spread throughout the world. By mapping the worldwide geographic distribution of genes for over 110 traits in over 1800 primarily aboriginal populations, the authors charted migrations and devised a clock by which to date evolutionary history. This monumental work is now available in a more affordable paperback edition without the myriad illustrations and maps, but containing the full text and partial appendices of the authors' pathbreaking endeavor.

The Genetic Code and the Origin of Life

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Publisher : Springer Science & Business Media
ISBN 13 : 0387268871
Total Pages : 266 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis The Genetic Code and the Origin of Life by : Lluis Ribas de Pouplana

Download or read book The Genetic Code and the Origin of Life written by Lluis Ribas de Pouplana and published by Springer Science & Business Media. This book was released on 2007-04-03 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: Early Thoughts on RNA and the Origin of Life The full impact of the essential role of the nucleic acids in biological systems was forcefully demonstrated by the research community in the 1950s. Although Avery and his collaborators had identified DNA as the genetic material responsible for the transformation of bacteria in 1944, it was not until the early 1950s that the Hershey-Chase experiments provided a more direct demonstration of this role. Finally, the structural DNA double helix proposed by Watson and Crick in 1953 clearly created a structural frame work for the role of DNA as both information carrier and as a molecule that could undergo the necessary replication needed for daughter cells. Research continued by Kornberg and his colleagues in the mid-1950s emphasized the biochemistry and enzymology of DNA replication. At the same time, there was a growing interest in the role of RNA. The 1956 dis covery by David Davies and myself showed that polyadenylic acid and polyuridylic acid could form a double-helical RNA molecule but that it differed somewhat from DN A A large number of experiments were subsequendy carried out with synthetic polyribonucleotides which illustrated that RNA could form even more complicated helical structures in which the specificity of hydrogen bonding was the key element in determining the molecular conformation. Finally, in I960,1 could show that it was possible to make a hybrid helix.

A Genetic History of New England Theology (Routledge Revivals)

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Publisher : Routledge
ISBN 13 : 1317599071
Total Pages : 589 pages
Book Rating : 4.3/5 (175 download)

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Book Synopsis A Genetic History of New England Theology (Routledge Revivals) by : Frank Hugh Foster

Download or read book A Genetic History of New England Theology (Routledge Revivals) written by Frank Hugh Foster and published by Routledge. This book was released on 2014-07-17 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: First published in 1907, this text provides a scientific treatment of New England theology and American dogmatic history. Frank Hugh Foster analyses the eighteenth-century rise of the school of New England theology, which became the dominant school of thought in New England congregationalism and, as argued by Foster, a ‘world phenomenon’. The chapters arise from readings of the various distinguished views of such contemporaries as Jonathan Edwards, Joseph Bellamy and Samuel Hopkins, placing them within the historical and theological context in which they developed. A fascinating and detailed title, this reissue will be of value to students of theology and Church history with a particular interest in the development of American religious thought.

The Magazine of History

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Publisher :
ISBN 13 :
Total Pages : 882 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis The Magazine of History by :

Download or read book The Magazine of History written by and published by . This book was released on 1905 with total page 882 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Evolution in Four Dimensions, revised edition

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Publisher : MIT Press
ISBN 13 : 0262525844
Total Pages : 577 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Evolution in Four Dimensions, revised edition by : Eva Jablonka

Download or read book Evolution in Four Dimensions, revised edition written by Eva Jablonka and published by MIT Press. This book was released on 2014-03-21 with total page 577 pages. Available in PDF, EPUB and Kindle. Book excerpt: A pioneering proposal for a pluralistic extension of evolutionary theory, now updated to reflect the most recent research. This new edition of the widely read Evolution in Four Dimensions has been revised to reflect the spate of new discoveries in biology since the book was first published in 2005, offering corrections, an updated bibliography, and a substantial new chapter. Eva Jablonka and Marion Lamb's pioneering argument proposes that there is more to heredity than genes. They describe four “dimensions” in heredity—four inheritance systems that play a role in evolution: genetic, epigenetic (or non-DNA cellular transmission of traits), behavioral, and symbolic (transmission through language and other forms of symbolic communication). These systems, they argue, can all provide variations on which natural selection can act. Jablonka and Lamb present a richer, more complex view of evolution than that offered by the gene-based Modern Synthesis, arguing that induced and acquired changes also play a role. Their lucid and accessible text is accompanied by artist-physician Anna Zeligowski's lively drawings, which humorously and effectively illustrate the authors' points. Each chapter ends with a dialogue in which the authors refine their arguments against the vigorous skepticism of the fictional “I.M.” (for Ipcha Mistabra—Aramaic for “the opposite conjecture”). The extensive new chapter, presented engagingly as a dialogue with I.M., updates the information on each of the four dimensions—with special attention to the epigenetic, where there has been an explosion of new research. Praise for the first edition “With courage and verve, and in a style accessible to general readers, Jablonka and Lamb lay out some of the exciting new pathways of Darwinian evolution that have been uncovered by contemporary research.” —Evelyn Fox Keller, MIT, author of Making Sense of Life: Explaining Biological Development with Models, Metaphors, and Machines “In their beautifully written and impressively argued new book, Jablonka and Lamb show that the evidence from more than fifty years of molecular, behavioral and linguistic studies forces us to reevaluate our inherited understanding of evolution.” —Oren Harman, The New Republic “It is not only an enjoyable read, replete with ideas and facts of interest but it does the most valuable thing a book can do—it makes you think and reexamine your premises and long-held conclusions.” —Adam Wilkins, BioEssays

The Magazine of History with Notes and Queries

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Publisher :
ISBN 13 :
Total Pages : 464 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis The Magazine of History with Notes and Queries by :

Download or read book The Magazine of History with Notes and Queries written by and published by . This book was released on 1905 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Writings on American History

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Publisher :
ISBN 13 :
Total Pages : 260 pages
Book Rating : 4.U/5 (183 download)

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Book Synopsis Writings on American History by :

Download or read book Writings on American History written by and published by . This book was released on 1914 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: