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High Containment Biosafety Laboratories
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Author :Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories Publisher :National Academies Press ISBN 13 :0309225760 Total Pages :216 pages Book Rating :4.3/5 (92 download)
Book Synopsis Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories
Download or read book Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories written by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories and published by National Academies Press. This book was released on 2012-03-16 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309486564 Total Pages :121 pages Book Rating :4.3/5 (94 download)
Book Synopsis Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts by : National Academies of Sciences, Engineering, and Medicine
Download or read book Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2019-05-01 with total page 121 pages. Available in PDF, EPUB and Kindle. Book excerpt: On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop.
Book Synopsis Oversight of High-Containment Biological Laboratories by : Frank Gottron
Download or read book Oversight of High-Containment Biological Laboratories written by Frank Gottron and published by DIANE Publishing. This book was released on 2009-12 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fed. gov¿t. responded to the 9/11 terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. High-containment labs. (HCL) play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. A key task for policymakers is to define their goals for enhancing oversight of HCL. Illustrations
Book Synopsis High-Containment Biosafety Laboratories by : Nancy Kingsbury
Download or read book High-Containment Biosafety Laboratories written by Nancy Kingsbury and published by DIANE Publishing. This book was released on 2009 with total page 33 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Dept. of Homeland Security (DHS) is proposing to move foot-and-mouth disease (FMD) research from its current location on a federally owned island off the northern tip of Long Island, NY -- and potentially into the U.S. mainland. FMD is the most highly infectious animal disease that is known. A single outbreak of FMD on the U.S. mainland could have significant economic consequences. This report evaluates the evidence DHS used to support its decision that FMD work can be done safely on the U.S. mainland, whether an island location provides any additional protection over and above that provided by modern high containment labs. on the mainland, and the economic consequences of an FMD outbreak on the U.S. mainland. Illus.
Author :Division on Engineering and Physical Sciences Publisher :National Academies Press ISBN 13 :0309039754 Total Pages :237 pages Book Rating :4.3/5 (9 download)
Book Synopsis Biosafety in the Laboratory by : Division on Engineering and Physical Sciences
Download or read book Biosafety in the Laboratory written by Division on Engineering and Physical Sciences and published by National Academies Press. This book was released on 1989-01-01 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.
Book Synopsis Biosafety in Microbiological and Biomedical Laboratories by : Centers for Disease Control (U.S.)
Download or read book Biosafety in Microbiological and Biomedical Laboratories written by Centers for Disease Control (U.S.) and published by . This book was released on 1988 with total page 156 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Laboratory Biosafety Manual by : World Health Organization
Download or read book Laboratory Biosafety Manual written by World Health Organization and published by World Health Organization. This book was released on 2004-12-28 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.
Author :United States Government Accountability Office Publisher :Createspace Independent Publishing Platform ISBN 13 :9781983987533 Total Pages :40 pages Book Rating :4.9/5 (875 download)
Book Synopsis High-Containment Biosafety Laboratories by : United States Government Accountability Office
Download or read book High-Containment Biosafety Laboratories written by United States Government Accountability Office and published by Createspace Independent Publishing Platform. This book was released on 2018-01-20 with total page 40 pages. Available in PDF, EPUB and Kindle. Book excerpt: High-Containment Biosafety Laboratories: Preliminary Observations on the Oversight of the Proliferation of BSL-3 and BSL-4 Laboratories in the United States
Book Synopsis Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by : National Research Council
Download or read book Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories written by National Research Council and published by National Academies Press. This book was released on 2012-04-02 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.
Book Synopsis High-Containment Laboratories by : Ann Wright
Download or read book High-Containment Laboratories written by Ann Wright and published by DIANE Publishing. This book was released on 2010 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: U.S. laboratories working with dangerous biological pathogens (commonly referred to as high-containment laboratories) have proliferated in recent years. As a result, the public is concerned about the oversight of these laboratories. The deliberate or accidental release of biological pathogens can have disastrous consequences. This report determines: (1) to what extent, and in what areas, the number of high-containment laboratories has increased in the U.S.; (2) which federal agency is responsible for tracking this expansion and determining the associated aggregate risks; and (3) lessons learned from highly publicized incidents at these laboratories and actions taken by the regulatory agencies. Charts and tables.
Book Synopsis Oversight of High-containment Biological Laboratories by : Frank Gottron
Download or read book Oversight of High-containment Biological Laboratories written by Frank Gottron and published by . This book was released on 2009 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt: The federal government responded to the September 11, 2001, terrorist attacks and the subsequent anthrax attacks with increased focus on and funding for biodefense. A key consideration in this response was addressing shortages in diagnostic, clinical, and research laboratory capacity. Several departments and agencies have increased or are in the process of increasing their laboratory capacity. High-containment laboratories play a critical role in the biodefense effort, offering the hope of better responses to an attack and a better understanding of the threat posed by bioterrorism. However, they also could increase the risk of a biological attack by serving as a potential source of materials or training. Indeed, the Commission on the Prevention of Weapons of Mass Destruction Proliferation and Terrorism recommends tightening government oversight of high-containment laboratories. Policymakers have become increasingly interested in the oversight of these facilities following reports of accidents, regulatory noncompliance, and community resistance. The increase in high-containment laboratory capacity has raised new policy questions and emphasized existing ones. How much laboratory capacity is enough? What is the necessary federal investment? Should laboratories be consolidated or dispersed? What plans exist to coordinate multiple agency efforts to expand high-containment laboratory capacity? Does increasing laboratory capacity increase the risk of accidents and the opportunity for purposeful misuse? What is an acceptable balance between the benefits these laboratories provide and the risks they pose?
Author :National Academies of Sciences, Engineering, and Medicine Publisher :National Academies Press ISBN 13 :0309458889 Total Pages :115 pages Book Rating :4.3/5 (94 download)
Book Synopsis Dual Use Research of Concern in the Life Sciences by : National Academies of Sciences, Engineering, and Medicine
Download or read book Dual Use Research of Concern in the Life Sciences written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-10-01 with total page 115 pages. Available in PDF, EPUB and Kindle. Book excerpt: The potential misuse of advances in life sciences research is raising concerns about national security threats. Dual Use Research of Concern in the Life Sciences: Current Issues and Controversies examines the U.S. strategy for reducing biosecurity risks in life sciences research and considers mechanisms that would allow researchers to manage the dissemination of the results of research while mitigating the potential for harm to national security.
Book Synopsis Laboratory Biorisk Management by : Reynolds M. Salerno
Download or read book Laboratory Biorisk Management written by Reynolds M. Salerno and published by CRC Press. This book was released on 2015-12-01 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.
Book Synopsis Potential Risks and Benefits of Gain-of-Function Research by : National Research Council
Download or read book Potential Risks and Benefits of Gain-of-Function Research written by National Research Council and published by National Academies Press. This book was released on 2015-04-13 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.
Author :Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee Publisher :The Stationery Office ISBN 13 :9780215521248 Total Pages :68 pages Book Rating :4.5/5 (212 download)
Book Synopsis Biosecurity in UK Research Laboratories by : Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee
Download or read book Biosecurity in UK Research Laboratories written by Great Britain. Parliament. House of Commons. Innovation, Universities, Science and Skills Committee and published by The Stationery Office. This book was released on 2008 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt: Possessing the high containment laboratories necessary to tackle existing and emergent infectious diseases of both humans and animals is of the utmost importance to the UK. A leak of Foot and Mouth disease from such a laboratory at Pirbright in 2007 is the most recent demonstration of how devastating infectious disease can be. It is critical that such an incident does not happen again. This Report outlines a number of shortcomings in the way capacity for high containment research is provided and highlights where the Government should take action. Primarily, the Committee concludes that there is a striking lack of co-ordination between organisations who sponsor and run high containment laboratories. No one organisation or Minister has the remit to maintain a strategic overview of capacity and to co-ordinate these laboratories. There is significant potential for collaboration at a more formal level to assess what facilities are available and make best use of them, identifying any gaps. There is also room for more co-ordination and standardisation of the vetting and training of staff working in this area. The report identifies shortcomings in the funding of high containment facilities, particularly for the significant cost of ongoing maintenance. A number of high containment laboratories have been neglected and the funding situation is uncertain. The Government must ensure that dependable funding is provided to maintain such facilities safely. The new regulatory framework to be introduced in the wake of the Pirbright outbreak is a positive step and should provide a framework in which those operating high containment facilities, given sufficient resources, should be able to continue their work to protect the UK from the threat of infectious disease.
Book Synopsis Biosafety and Biosecurity Issues in High-Containment Laboratories by : Damon S. Samuels
Download or read book Biosafety and Biosecurity Issues in High-Containment Laboratories written by Damon S. Samuels and published by Nova Science Publishers. This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Stringent protocols and engineering are used to contain the most dangerous pathogens, therefore these facilities are often referred to as high-containment laboratories. High-containment laboratories play a critical role in the biodefense effort, offering the hope of better responses to a biological attack and a better understanding of the bioterrorism threat. However, they could also increase the risk of a biological attack by being a source of materials or training. This book examines the biosafety and biosecurity issues in high-containment laboratories across the United States.
Book Synopsis High-Containment Biosafety Laboratories Preliminary Observations on the Oversight of the Proliferation of BSL-3 and BSL-4 Laboratories in the United States by :
Download or read book High-Containment Biosafety Laboratories Preliminary Observations on the Oversight of the Proliferation of BSL-3 and BSL-4 Laboratories in the United States written by and published by . This book was released on 2007 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: