Harnessing The Power Of Viruses

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Harnessing the Power of Viruses

Author : Boriana Marintcheva
Publisher : Academic Press
ISBN 13 : 0128105151
Total Pages : 298 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Harnessing the Power of Viruses by : Boriana Marintcheva

Download or read book Harnessing the Power of Viruses written by Boriana Marintcheva and published by Academic Press. This book was released on 2017-11-13 with total page 298 pages. Available in PDF, EPUB and Kindle. Book excerpt: Harnessing the Power of Viruses explores the application of scientific knowledge about viruses and their lives to solve practical challenges and further advance molecular sciences, medicine and agriculture. The book contains virus-based tools and approaches in the fields of: i) DNA manipulations in vitro and in vivo; ii) Protein expression and characterization; and iii) Virus- Host interactions as a platform for therapy and biocontrol are discussed. It steers away from traditional views of viruses and technology, focusing instead on viral molecules and molecular processes that enable science to better understand life and offer means for addressing complex biological phenomena that positively influence everyday life. The book is written at an intermediate level and is accessible to novices who are willing to acquire a basic level of understanding of key principles in molecular biology, but is also ideal for advanced readers interested in expanding their biological knowledge to include practical applications of molecular tools derived from viruses. - Explores virus-based tools and approaches in DNA manipulation, protein expression and characterization and virus-host interactions - Provides a dedicated focus on viral molecules and molecular processes that enable science to better understand life and address complex biological phenomena - Includes an overview of modern technologies in biology that were developed using viral components/elements and knowledge about viral processes

Gene Therapy for Viral Infections

Author : Patrick Arbuthnot
Publisher : Academic Press
ISBN 13 : 0124114520
Total Pages : 391 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Gene Therapy for Viral Infections by : Patrick Arbuthnot

Download or read book Gene Therapy for Viral Infections written by Patrick Arbuthnot and published by Academic Press. This book was released on 2015-06-01 with total page 391 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options. Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors. Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology. - Provides coverage of gene therapy for a variety of infections, including HBV, HCV, HIV, hemorrhagic fever viruses, and respiratory and other viral infections - Bridges the gap between the basic science and the important medical applications of this technology - Features a broad approach to the topic, including an essential overview and the applications of gene therapy, synthetic RNA, and other antiviral strategies that involve nucleic acid engineering - Presents perspectives on the future use of nucleic acids as a novel class of antiviral drugs - Arms the reader with the cutting-edge information needed to stay abreast of this developing field

Bugs as Drugs

Author : Robert A. Britton
Publisher : John Wiley & Sons
ISBN 13 : 1683673026
Total Pages : 725 pages
Book Rating : 4.6/5 (836 download)

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Book Synopsis Bugs as Drugs by : Robert A. Britton

Download or read book Bugs as Drugs written by Robert A. Britton and published by John Wiley & Sons. This book was released on 2018-02-01 with total page 725 pages. Available in PDF, EPUB and Kindle. Book excerpt: Examining the enormous potential of microbiome manipulation to improve health Associations between the composition of the intestinal microbiome and many human diseases, including inflammatory bowel disease, cardiovascular disease, metabolic disorders, and cancer, have been elegantly described in the past decade. Now, whole-genome sequencing, bioinformatics, and precision gene-editing techniques are being combined with centuries-old therapies, such as fecal microbiota transplantation, to translate current research into new diagnostics and therapeutics to treat complex diseases. Bugs as Drugs provides a much-needed overview of microbes in therapies and will serve as an excellent resource for scientists and clinicians as they carry out research and clinical studies on investigating the roles the microbiota plays in health and disease. In Bugs as Drugs, editors Robert A. Britton and Patrice D. Cani have assembled a fascinating collection of reviews that chart the history, current efforts, and future prospects of using microorganisms to fight disease and improve health. Sections cover traditional uses of probiotics, next-generation microbial therapeutics, controlling infectious diseases, and indirect strategies for manipulating the host microbiome. Topics presented include: How well-established probiotics support and improve host health by improving the composition of the intestinal microbiota of the host and by modulating the host immune response. The use of gene editing and recombinant DNA techniques to create tailored probiotics and to characterize next-generation beneficial microbes. For example, engineering that improves the anti-inflammatory profile of probiotics can reduce the number of colonic polyps formed, and lactobacilli can be transformed into targeted delivery systems carrying therapeutic proteins or bioengineered bacteriophage. The association of specific microbiota composition with colorectal cancer, liver diseases, osteoporosis, and inflammatory bowel disease. The gut microbiota has been proposed to serve as an organ involved in regulation of inflammation, immune function, and energy homeostasis. Fecal microbiota transplantation as a promising treatment for numerous diseases beyond C. difficile infection. Practical considerations for using fecal microbiota transplantation are provided, while it is acknowledged that more high-quality evidence is needed to ascertain the importance of strain specificity in positive treatment outcomes. Because systems biology approaches and synthetic engineering of microbes are now high-throughput and cost-effective, a much wider range of therapeutic possibilities can be explored and vetted. If you are looking for online access to the latest clinical microbiology content, please visit www.wiley.com/learn/clinmicronow.

Viral Vectors

Author : Michael G. Kaplitt
Publisher : Academic Press
ISBN 13 : 008054357X
Total Pages : 525 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Viral Vectors by : Michael G. Kaplitt

Download or read book Viral Vectors written by Michael G. Kaplitt and published by Academic Press. This book was released on 1995-08-14 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic manipulation of the adult mammalian nervous system is one of the most exciting areas in contemporary neurobiology. The explosive growth of this field has been facilitated by harnessing the power of viruses to transfer genetic material into mammalian cells.Viral Vectors: Gene Therapy and Neuroscience Applications represents the first comprehensive review of viral vector applications to the nervous system by leaders in virology, molecular neurobiology, neuroanatomy, and developmental neurobiology. It serves both as a source of fundamental information for those newly interested in viral vectors and as a compilation of state-of-the-art technologies and applications for more experienced researchers.This work provides expert background information on viral systems, and the broad range of applications will help readers appreciate the current and future impact of viral vectors in both clinical and basic neuroscience.

The Application of Viruses to Biotechnology

Author : Carla Varanda
Publisher : Mdpi AG
ISBN 13 : 9783036525396
Total Pages : 306 pages
Book Rating : 4.5/5 (253 download)

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Book Synopsis The Application of Viruses to Biotechnology by : Carla Varanda

Download or read book The Application of Viruses to Biotechnology written by Carla Varanda and published by Mdpi AG. This book was released on 2021-12-21 with total page 306 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.

The Baculoviruses

Author : Lois K. Miller
Publisher : Springer Science & Business Media
ISBN 13 : 9780306456411
Total Pages : 480 pages
Book Rating : 4.4/5 (564 download)

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Book Synopsis The Baculoviruses by : Lois K. Miller

Download or read book The Baculoviruses written by Lois K. Miller and published by Springer Science & Business Media. This book was released on 1997-07-31 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: The past decade has witnessed an explosion of information on the molecular biology of insect viruses and a frenzy of activity in applying this information to medicine and agriculture. Genetically engineered baculoviruses are presently being tested for commercial use as pesticides, and the study of such viruses is also revealing remarkable insights into basic cellular processes such as apoptosis. This comprehensive volume provides readers with knowledge of basic and applied baculovirology so that current literature in the field can be appreciated.

The Beautiful Cure

Author : Daniel M. Davis
Publisher : University of Chicago Press
ISBN 13 : 022637114X
Total Pages : 271 pages
Book Rating : 4.2/5 (263 download)

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Book Synopsis The Beautiful Cure by : Daniel M. Davis

Download or read book The Beautiful Cure written by Daniel M. Davis and published by University of Chicago Press. This book was released on 2021-03-19 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: “A terrific book by a consummate storyteller and scientific expert considers the past and future of the body’s ability to fight disease and heal itself.” —Adam Rutherford, The Guardian The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy. “Visceral.” —The Wall Street Journal “Illuminating.” —Publishers Weekly “Heroic.” —Science

Wyrm

Author : Mark Fabi
Publisher : Spectra
ISBN 13 : 9780553578089
Total Pages : 0 pages
Book Rating : 4.5/5 (78 download)

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Book Synopsis Wyrm by : Mark Fabi

Download or read book Wyrm written by Mark Fabi and published by Spectra. This book was released on 1998 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this stunning cautionary tale, a team of technical wizards tracks a mysterious computer virus to an elusive genius. As the millennium draws near, the virus hunters realize that the brilliant villain has control of the World Wide Web--and his deadly bug has the power to bring everyone's prophecies to fruition.

The Germ Code

Author : Jason Tetro
Publisher : Doubleday Canada
ISBN 13 : 0385678533
Total Pages : 274 pages
Book Rating : 4.3/5 (856 download)

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Book Synopsis The Germ Code by : Jason Tetro

Download or read book The Germ Code written by Jason Tetro and published by Doubleday Canada. This book was released on 2013-11-05 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the dawn of the human race, germs have been making us sick. Whether the ailment is a cold, the flu, diabetes, obesity or certain cancers, the likely cause is germs. Our ancient enemies have four families - bacteria, viruses, fungi, and protozoa - and many names: Ebola, E. coli, salmonella, norovirus, gonorrhea. . . Human beings are engaged in a "war on germs," in which we develop ever-more sophisticated weapons and defensive strategies. But it is a war we can never win. Our best plan for staying as healthy is to choose our battles carefully, and try to co-exist with germs as best we can. The Germ Code is a wise, witty and wonderfully readable guide to our relationship with these infinitesimal but infinitely powerful creatures. Microbiologist Jason Tetro takes us outside the lab and shows the enormous influence of germs upon humanity's past, present and future. He unlocks the mysteries of "the germ code" to reveal how these organisms have exploited our every activity and colonized every corner of the earth. From his own research and personal experience, Tetro relates how the most recent flu pandemic happened, how others may have been averted and how more may come about if we aren't careful. He also explains that not every germ is our foe, and offers advice on harnessing the power of good germs to stay healthy and make our planet a better place. The Germ Code is a fascinating journey through an unseen world, an essential manual to living in harmony with germs and a life-enhancing (as well as life-saving!) good read.

The Viral Network

Author : Theresa MacPhail
Publisher : Cornell University Press
ISBN 13 : 0801454883
Total Pages : 247 pages
Book Rating : 4.8/5 (14 download)

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Book Synopsis The Viral Network by : Theresa MacPhail

Download or read book The Viral Network written by Theresa MacPhail and published by Cornell University Press. This book was released on 2015-03-03 with total page 247 pages. Available in PDF, EPUB and Kindle. Book excerpt: In The Viral Network, Theresa MacPhail examines our collective fascination with and fear of viruses through the lens of the 2009 H1N1 pandemic. In April 2009, a novel strain of H1N1 influenza virus resulting from a combination of bird, swine, and human flu viruses emerged in Veracruz, Mexico. The Director-General of the World Health Organization (WHO) announced an official end to the pandemic in August 2010. Experts agree that the global death toll reached 284,500. The public health response to the pandemic was complicated by the simultaneous economic crisis and by the public scrutiny of official response in an atmosphere of widespread connectivity. MacPhail follows the H1N1 influenza virus's trajectory through time and space in order to construct a three-dimensional picture of what happens when global public health comes down with a case of the flu.The Viral Network affords a rare look inside the U.S. Centers for Disease Control, as well as Hong Kong’s virology labs and Centre for Health Protection, during a pandemic. MacPhail looks at the day-to-day practices of virologists and epidemiologists to ask questions about the production of scientific knowledge, the construction of expertise, disease narratives, and the different "cultures" of public health in the United States, Europe, Hong Kong, and China. The chapters of the book move from the micro to the macro, from Hong Kong to Atlanta, from the lab to the WHO, from the pandemic past in 1918 to the future. The various historical, scientific, and cultural narratives about flu recounted in this book show how biological genes and cultural memes become interwoven in the stories we tell during a pandemic. Ultimately, MacPhail argues that the institution of global public health is as viral as the viruses it tracks, studies, and helps to contain or eradicate. The "global" is itself viral in nature.

Exploring the Frontiers of Innovation to Tackle Microbial Threats

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309675332
Total Pages : 179 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Exploring the Frontiers of Innovation to Tackle Microbial Threats by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring the Frontiers of Innovation to Tackle Microbial Threats written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-09-10 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: On December 4â€"5, 2019, the National Academies of Sciences, Engineering, and Medicine held a 1.5-day public workshop titled Exploring the Frontiers of Innovation to Tackle Microbial Threats. The workshop participants examined major advances in scientific, technological, and social innovations against microbial threats. Such innovations include diagnostics, vaccines (both development and production), and antimicrobials, as well as nonpharmaceutical interventions and changes in surveillance. This publication summarizes the presentations and discussions from the workshop.

Molecular and Cell Biology For Dummies

Author : Rene Fester Kratz
Publisher : John Wiley & Sons
ISBN 13 : 0470531045
Total Pages : 384 pages
Book Rating : 4.4/5 (75 download)

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Book Synopsis Molecular and Cell Biology For Dummies by : Rene Fester Kratz

Download or read book Molecular and Cell Biology For Dummies written by Rene Fester Kratz and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: Your hands-on study guide to the inner world of the cell Need to get a handle on molecular and cell biology? This easy-to-understand guide explains the structure and function of the cell and how recombinant DNA technology is changing the face of science and medicine. You discover how fundamental principles and concepts relate to everyday life. Plus, you get plenty of study tips to improve your grades and score higher on exams! Explore the world of the cell take a tour inside the structure and function of cells and see how viruses attack and destroy them Understand the stuff of life (molecules) get up to speed on the structure of atoms, types of bonds, carbohydrates, proteins, DNA, RNA, and lipids Watch as cells function and reproduce see how cells communicate, obtain matter and energy, and copy themselves for growth, repair, and reproduction Make sense of genetics learn how parental cells organize their DNA during sexual reproduction and how scientists can predict inheritance patterns Decode a cell's underlying programming examine how DNA is read by cells, how it determines the traits of organisms, and how it's regulated by the cell Harness the power of DNA discover how scientists use molecular biology to explore genomes and solve current world problems Open the book and find: Easy-to-follow explanations of key topics The life of a cell what it needs to survive and reproduce Why molecules are so vital to cells Rules that govern cell behavior Laws of thermodynamics and cellular work The principles of Mendelian genetics Useful Web sites Important events in the development of DNA technology Ten great ways to improve your biology grade

Emerging Viral Diseases

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309314003
Total Pages : 310 pages
Book Rating : 4.3/5 (93 download)

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Book Synopsis Emerging Viral Diseases by : Institute of Medicine

Download or read book Emerging Viral Diseases written by Institute of Medicine and published by National Academies Press. This book was released on 2015-03-19 with total page 310 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.

Virusphere

Author : Frank Ryan
Publisher : Rowman & Littlefield
ISBN 13 : 1633886050
Total Pages : 289 pages
Book Rating : 4.6/5 (338 download)

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Book Synopsis Virusphere by : Frank Ryan

Download or read book Virusphere written by Frank Ryan and published by Rowman & Littlefield. This book was released on 2020-02-01 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fascinating and long overdue examination of viruses - from what they are and what they do, to the vital role they have played in human history.What are viruses? Do they rely on genes, like all other forms of life? Do they follow the same patterns of evolution as plants and animals?Dr. Frank Ryan answers these questions and many more in a sweeping tour of illnesses caused by viruses. He examines the common cold, measles, chicken pox, herpes, mumps, and rubella, as well as less familiar maladies, such as rabies, "breakbone fever," hemorrhagic fevers like Ebola, and virus-induced cancers. Along the way, readers will learn about the behaviors of viruses and what drives them to infect a human host. Ryan explains the role of viruses in the evolution of life, revealing how viruses have changed us at the most intimate level, helping to make us quintessentially human.

Advanced Concepts in Human Immunology: Prospects for Disease Control

Author : Pooja Jain
Publisher : Springer Nature
ISBN 13 : 3030339467
Total Pages : 413 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Advanced Concepts in Human Immunology: Prospects for Disease Control by : Pooja Jain

Download or read book Advanced Concepts in Human Immunology: Prospects for Disease Control written by Pooja Jain and published by Springer Nature. This book was released on 2020-08-11 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.

Cancer Associated Viruses

Author : Erle S. Robertson
Publisher : Springer Science & Business Media
ISBN 13 : 1461400163
Total Pages : 869 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Cancer Associated Viruses by : Erle S. Robertson

Download or read book Cancer Associated Viruses written by Erle S. Robertson and published by Springer Science & Business Media. This book was released on 2012-02-14 with total page 869 pages. Available in PDF, EPUB and Kindle. Book excerpt: The acknowledgment that viruses are potent biological factors in driving many cancers have seen a dramatic upsurge in recent years in large part to the success of the human papilloma virus vaccine against invasive cervical carcinomas and followed by the awarding of the noble prize in medicine in 2008 to Dr. Harald zurHausen who identified the link between papilloma virus and cervical cancers. Over the last few years there have been some volumes addressing different aspects of viruses and cancers and to some extent focusing on the DNA viruses, more specifically the human DNA viruses. This proposed volume will attempt to review and address the major gaps in current knowledge in DNA viruses as well as RNA viruses bringing a historical perspective of where studies began to a more recent molecular approach and vaccine successes in tumor viruses. We will also cover other known oncogenic viruses associated cancers in other mammals in addition to humans.

Stealth Adapted Viruses; Alternative Cellular Energy (Ace) & Kelea Activated Water

Author : W. John Martin MD PhD.
Publisher : AuthorHouse
ISBN 13 : 1496904974
Total Pages : 467 pages
Book Rating : 4.4/5 (969 download)

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Book Synopsis Stealth Adapted Viruses; Alternative Cellular Energy (Ace) & Kelea Activated Water by : W. John Martin MD PhD.

Download or read book Stealth Adapted Viruses; Alternative Cellular Energy (Ace) & Kelea Activated Water written by W. John Martin MD PhD. and published by AuthorHouse. This book was released on 2014-06-09 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is intended to help mankind realize the many medical and agricultural benefits of enhancing the alternative cellular energy (ACE) pathway. The research stemmed from the discovery of stealth adapted viruses, which bypass cellular immunity. Stealth adapted viruses were implicated in mental illnesses over 20 years ago. The concept evoked political resistance because some stealth adapted viruses unequivocally arose as contaminants of polio vaccines and likely led to the formation of HIV, the AIDS virus. The ACE pathway is distinct from the immune system. It also fundamentally differs from cellular energy obtained from food calories. Rather the ACE pathway is an expression of a kinetic energy limiting electrostatic attraction or KELEA. The physics of KELEA needs to be actively pursued. The book consists of six-academic-style chapters followed by narratives regarding political barriers and specific disease entities. Patients support groups and other organizations will be assisted in conducting their own clinical validation studies. Let the work begin!