Handbook Of Dynein

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Handbook of Dynein

Author : Keiko Hirose
Publisher : CRC Press
ISBN 13 : 981430333X
Total Pages : 406 pages
Book Rating : 4.8/5 (143 download)

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Book Synopsis Handbook of Dynein by : Keiko Hirose

Download or read book Handbook of Dynein written by Keiko Hirose and published by CRC Press. This book was released on 2012-02-22 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give readers a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. This is a useful handbook for frontline researchers as well as a textbook for advanced students. Besides comprehensive cover of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry. The reports include in vitro studies of the motility of reconstituted complexes and in vivo studies of organisms expressing mutant dyneins. The recent technical improvements described, which have played an important part in recent advances, include the expression and preparation of recombinant dynein heavy chains or individual subdomains.

Handbook of Dynein (Second Edition)

Author : Keiko Hirose
Publisher : CRC Press
ISBN 13 : 0429664710
Total Pages : 355 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Handbook of Dynein (Second Edition) by : Keiko Hirose

Download or read book Handbook of Dynein (Second Edition) written by Keiko Hirose and published by CRC Press. This book was released on 2019-05-28 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyneins are molecular motors that are involved in various cellular processes, such as cilia and flagella motility, vesicular transport, and mitosis. Since the first edition of this book was published in 2012, there has been a significant breakthrough: the crystal structures of the motor domains of cytoplasmic dynein have been solved and the previously unknown details of this huge and complex molecule have been unveiled. This new edition contains 14 chapters written by researchers in the US, Europe, and Asia, including 3 new chapters that incorporate new fields. The other chapters have also been substantially updated. Compared with the earlier edition, this book focuses more on the motile mechanisms of dynein, especially by biophysical methods such as cryo-EM, X-ray crystallography, and single-molecule nanometry. It is a major handbook for frontline researchers as well as for advanced students studying cell biology, molecular biology, biochemistry, biophysics, and structural biology.

Handbook of Dynein (Second Edition)

Author : Keiko Hirose
Publisher : CRC Press
ISBN 13 : 0429667434
Total Pages : 436 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Handbook of Dynein (Second Edition) by : Keiko Hirose

Download or read book Handbook of Dynein (Second Edition) written by Keiko Hirose and published by CRC Press. This book was released on 2019-05-28 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyneins are molecular motors that are involved in various cellular processes, such as cilia and flagella motility, vesicular transport, and mitosis. Since the first edition of this book was published in 2012, there has been a significant breakthrough: the crystal structures of the motor domains of cytoplasmic dynein have been solved and the previously unknown details of this huge and complex molecule have been unveiled. This new edition contains 14 chapters written by researchers in the US, Europe, and Asia, including 3 new chapters that incorporate new fields. The other chapters have also been substantially updated. Compared with the earlier edition, this book focuses more on the motile mechanisms of dynein, especially by biophysical methods such as cryo-EM, X-ray crystallography, and single-molecule nanometry. It is a major handbook for frontline researchers as well as for advanced students studying cell biology, molecular biology, biochemistry, biophysics, and structural biology.

Dyneins

Author : Stephen M. King
Publisher : Academic Press
ISBN 13 : 0128097019
Total Pages : 530 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Dyneins by : Stephen M. King

Download or read book Dyneins written by Stephen M. King and published by Academic Press. This book was released on 2017-11-28 with total page 530 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dyneins: Structure, Biology and Disease, Second Edition, offers a broad view of dyneins mechanics, dysfunction, and disease, providing an overview of dyneins from structure and function, to dysfunction and disease. Since the first edition, enormous strides have been taken in understanding dynein structure, its organization in the axoneme, single molecule motor mechanics, and the consequences of defects for human biology, disease, and development. To account for these enormous strides, the second edition is extensively revised. Additionally, the coverage has expanded from 24 to 42 chapters, and is now housed in two volumes. Much of the expanded coverage occurs in Volume 2 which focuses on dynein dysfunction and disease, such as the role of dynein and cancer. Volume 1 covers the history and evolution of dyneins, dyneins in ciliary biology, and cytoplasmic dynein biology, while Volume 2 covers the structure and mechanics of dynein motors and dynein dysfunction and disease. - Presents a broad-based and up-to date view of dynein mechanics, dysfunction, and disease - Contains approaches from genetics, molecular biology, biochemistry, and biophysics discussed - Provides companion website with movies of dynamic cell behavior - Includes extensive chapters written by leading, global experts

The Nanobiotechnology Handbook

Author : Yubing Xie
Publisher : CRC Press
ISBN 13 : 1439838704
Total Pages : 692 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis The Nanobiotechnology Handbook by : Yubing Xie

Download or read book The Nanobiotechnology Handbook written by Yubing Xie and published by CRC Press. This book was released on 2012-11-16 with total page 692 pages. Available in PDF, EPUB and Kindle. Book excerpt: A thorough overview of nanobiotechnology and its place in advances in applied science and engineering, The Nanobiotechnology Handbook combines contributions from physics, bioorganic and bioinorganic chemistry, molecular and cellular biology, materials science, and medicine as well as from mechanical, electrical, chemical, and biomedical engineering

New Approaches to Study Ciliopathies and Centrioles-Related Genetic Disorders

Author : Carlo Iomini
Publisher : Frontiers Media SA
ISBN 13 : 2889661407
Total Pages : 154 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis New Approaches to Study Ciliopathies and Centrioles-Related Genetic Disorders by : Carlo Iomini

Download or read book New Approaches to Study Ciliopathies and Centrioles-Related Genetic Disorders written by Carlo Iomini and published by Frontiers Media SA. This book was released on 2020-10-11 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Optical Tweezers

Author : Arne Gennerich
Publisher : Springer Nature
ISBN 13 : 1071622293
Total Pages : 753 pages
Book Rating : 4.0/5 (716 download)

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Book Synopsis Optical Tweezers by : Arne Gennerich

Download or read book Optical Tweezers written by Arne Gennerich and published by Springer Nature. This book was released on 2022-09-05 with total page 753 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed volume explores a wide variety of techniques involving optical tweezers, a technology that has become increasingly more accessible to a broad range of researchers. Beginning with recent technical advances, the book continues by covering the application of optical tweezers to study DNA-protein interactions and DNA motors, protocols to perform protein (un)folding experiments, the application of optical tweezers to study actin- and microtubule-associated motor proteins, and well as protocols for investigating the function and mechanical properties of microtubules and intermediate filaments, and more. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Optical Tweezers: Methods and Protocols, Second Edition serves as an ideal resource for expanding the accessibility and use of optical traps by scientists of diverse disciplines.

Handbook of Biochemical Kinetics

Author : Daniel L. Purich
Publisher : Elsevier
ISBN 13 : 0080521932
Total Pages : 811 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Handbook of Biochemical Kinetics by : Daniel L. Purich

Download or read book Handbook of Biochemical Kinetics written by Daniel L. Purich and published by Elsevier. This book was released on 1999-10-26 with total page 811 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical kinetics refers to the rate at which a reaction takes place. Kinetic mechanisms have played a major role in defining the metabolic pathways, the mechanistic action of enzymes, and even the processing of genetic material. The Handbook of Biochemical Kinetics provides the "underlying scaffolding" of logic for kinetic approaches to distinguish rival models or mechanisms. The handbook also comments on techniques and their likely limitations and pitfalls, as well as derivations of fundamental rate equations that characterize biochemical processes.Key Features* Over 750 pages devoted to theory and techniques for studying enzymic and metabolic processes* Over 1,500 definitions of kinetic and mechanistic terminology, with key references* Practical advice on experimental design of kinetic experiments* Extended step-by-step methods for deriving rate equations* Over 1,000 enzymes, complete with EC numbers, reactions catalyzed, and references to reviews and/or assay methods* Over 5,000 selected references to kinetic methods appearing in the Methods in Enzymology series* 72-page Wordfinder that allows the reader to search by keywords* Summaries of mechanistic studies on key enzymes and protein systems* Over 250 diagrams, figures, tables, and structures

Flagellar Mechanics and Sperm Guidance

Author : Jacky J. Cosson
Publisher : Bentham Science Publishers
ISBN 13 : 1681081288
Total Pages : 457 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Flagellar Mechanics and Sperm Guidance by : Jacky J. Cosson

Download or read book Flagellar Mechanics and Sperm Guidance written by Jacky J. Cosson and published by Bentham Science Publishers. This book was released on 2015-11-04 with total page 457 pages. Available in PDF, EPUB and Kindle. Book excerpt: Experimental research using spermatozoa, a highly specialized cell with organelles involved in gene transfer, energy supply and cellular motility, has always occupied the forefront of studies in cell and reproductive biology. Several spermatological experiments have focused on the attraction of a spermatozoon toward the egg – sperm chemotaxis or sperm guidance. This process ubiquitously occurs in the reproductive system of many organisms. After its discovery in the late 19th century in plants, sperm chemotaxis is known to play a crucial role in fertilization success in both plants and animals. Spermatology has expanded in focus in recent years, as the structure of molecules relevant to sperm chemotaxis has been recently determined in several species of invertebrates and vertebrates, which promises remarkable progress for understanding events relevant to sexual reproduction. Reflecting upon these trends in the long history of sperm chemotaxis, Flagellar Mechanics and Sperm Guidance gathers leaders in the field of spermatology, who have presented their experimental research on the chemical cues behind flagellate behavior in a variety of organisms including bikonts and spermatozoa of marine invertebrates and vertebrates (fish, amphibians and mammals). Reviews presented in this monograph provide both basic and detailed information on the initiation and activation of sperm motility at spawning, sperm thermotaxis, and other mechanics such as mathematical models of a spermatozoon swimming. A comparison between features of sperm chemotaxis among different organisms is also given. Flagellar Mechanics and Sperm Guidance will stir interest in spermatology research among a broad variety of readers including researchers, Ph.D. students studying reproductive biology and teachers involved in advanced biology courses.

Handbook of Pediatric Autopsy Pathology

Author : Enid Gilbert-Barness
Publisher : Springer Science & Business Media
ISBN 13 : 146146711X
Total Pages : 769 pages
Book Rating : 4.4/5 (614 download)

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Book Synopsis Handbook of Pediatric Autopsy Pathology by : Enid Gilbert-Barness

Download or read book Handbook of Pediatric Autopsy Pathology written by Enid Gilbert-Barness and published by Springer Science & Business Media. This book was released on 2013-09-19 with total page 769 pages. Available in PDF, EPUB and Kindle. Book excerpt: Pathologists have long recognized that pediatric autopsy requires great care in technique and dissection to ensure that easily overlooked malformations are recognized and accurate diagnoses are made. The highly experienced authors have created a new edition of Handbook of Pediatric Autopsy Pathology, a comprehensive reference guide to the actual performance of the pediatric autopsy and the optimal recognition and interpretation of pathologic findings. The Handbook of Pediatric Autopsy Pathology, Second Edition covers the spectrum of pediatric pathology with particular reference to those conditions that can be identified at autopsy. New and updated material includes microbiological studies, particularly with the advent of newly described micro-organisms causing disease. The volume also addresses new developments in metabolic diseases, new techniques of ultrasound imaging, and specialized laboratory testing. Furthermore, the book provides a wealth of practical information and bibliographic citations throughout, new copious illustrations and line drawings, numerous standard reference tables, and appendices at the end of multiple chapters. Authored by authorities in the field, Handbook of Pediatric Autopsy Pathology, Second Edition is a valuable resource that will assist general and pediatric pathologists, neonatologists, interns and residents in training, as well as specialists in cytogenetics and ultrasound technicians in understanding the manner and cause of death in its broadest and comprehensive sense.

Handbook of Physiology: The respiratory system

Author :
Publisher :
ISBN 13 :
Total Pages : 592 pages
Book Rating : 4.:/5 (311 download)

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Book Synopsis Handbook of Physiology: The respiratory system by :

Download or read book Handbook of Physiology: The respiratory system written by and published by . This book was released on 1985 with total page 592 pages. Available in PDF, EPUB and Kindle. Book excerpt:

ERS Handbook of Paediatric Respiratory Medicine

Author : Ernst Eber
Publisher : European Respiratory Society
ISBN 13 : 1849841314
Total Pages : 915 pages
Book Rating : 4.8/5 (498 download)

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Book Synopsis ERS Handbook of Paediatric Respiratory Medicine by : Ernst Eber

Download or read book ERS Handbook of Paediatric Respiratory Medicine written by Ernst Eber and published by European Respiratory Society. This book was released on 2021 with total page 915 pages. Available in PDF, EPUB and Kindle. Book excerpt: The 19 sections of this second edition of the ERS Handbook of Paediatric Respiratory Medicine cover the whole spectrum of paediatric respiratory medicine, from anatomy and development to disease, rehabilitation and treatment. The editors have brought together leading clinicians to produce a thorough and easy-to-read reference tool. The Handbook is structured to accompany the paediatric HERMES syllabus, making it an essential resource for anyone interested in this field and an ideal educational training guide.

The Kinesin Superfamily Handbook

Author : Claire T. Friel
Publisher : CRC Press
ISBN 13 : 0429958242
Total Pages : 141 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis The Kinesin Superfamily Handbook by : Claire T. Friel

Download or read book The Kinesin Superfamily Handbook written by Claire T. Friel and published by CRC Press. This book was released on 2020-05-13 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book brings together current information on the families that make up the kinesin superfamily of molecular motors in one comprehensive text; an ideal reference for researchers looking to make comparisons between different families, for specific information on an individual family, or simply for an overview of the kinesin superfamily. Information is clearly structured and grouped according to individual families and organised in a standardised way, allowing the reader to easily search and retrieve information on this large superfamily of molecular motors and understand how its individual members carry out a diverse variety of cellular functions. Features : The first book dedicated to the entire kinesin superfamily Enables a fuller understanding of this family of proteins, which is becoming an increasing focus of research due to its involvement in diseases such as cancer, neuropathies and ciliopathies Written in a manner accessible to a range of researchers in the life and medical sciences, including biophysicists, biochemists and medical researchers. Chapters 4 and 11 of this book are freely available as downloadable Open Access PDFs at http://www.taylorfrancis.com under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) 4.0 license.

Molecular Motors

Author : Manfred Schliwa
Publisher : John Wiley & Sons
ISBN 13 : 3527605657
Total Pages : 604 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Molecular Motors by : Manfred Schliwa

Download or read book Molecular Motors written by Manfred Schliwa and published by John Wiley & Sons. This book was released on 2006-03-06 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: The latest knowledge on molecular motors is vital for the understanding of a wide range of biological and medical topics: cell motility, organelle movement, virus transport, developmental asymmetry, myopathies, and sensory defects are all related to the function or malfunction of these minute molecular machines. Since there is a vast amount of information on motor mechanisms and potential biomedical and nanobiotechnological applications, this handbook fulfills the need for a collection of current research results on the functionality, regulation, and interactions of cytoskeletal, DNA, and rotary motors. Here, leading experts present a concise insight, ranging from atomic structure, biochemistry, and biophysics to cell biology, developmental biology and pathology. Basic principles and applications make this book a valuable reference tool for researchers, professionals, and clinicians alike - all set to become a "classic" in the years to come.

Handbook of Mitochondrial Dysfunction

Author : Shamim I. Ahmad
Publisher : CRC Press
ISBN 13 : 0429811772
Total Pages : 503 pages
Book Rating : 4.4/5 (298 download)

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Book Synopsis Handbook of Mitochondrial Dysfunction by : Shamim I. Ahmad

Download or read book Handbook of Mitochondrial Dysfunction written by Shamim I. Ahmad and published by CRC Press. This book was released on 2019-05-15 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key Features Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseases Explores a wide variety of diseases caused by dysfunctional mitochondria.

Reconstituting the Cytoskeleton

Author :
Publisher : Academic Press
ISBN 13 : 0123984807
Total Pages : 539 pages
Book Rating : 4.1/5 (239 download)

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Book Synopsis Reconstituting the Cytoskeleton by :

Download or read book Reconstituting the Cytoskeleton written by and published by Academic Press. This book was released on 2014-03-11 with total page 539 pages. Available in PDF, EPUB and Kindle. Book excerpt: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cytoskeletal structure, including such topics as rotational movement of formins studied by fluorescence polarization microscopy, in vitro assembly assays for bacterial actin filaments, and modulators of microtubule plus end growth. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers cytoskeletal structure - Contains chapters with such topics as reconstitution of organelle transport and assaying microtubule nucleation by gamma-tubulin ring complex.

The Chlamydomonas Sourcebook

Author : Elizabeth H. Harris
Publisher : Elsevier
ISBN 13 : 1483288609
Total Pages : 795 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis The Chlamydomonas Sourcebook by : Elizabeth H. Harris

Download or read book The Chlamydomonas Sourcebook written by Elizabeth H. Harris and published by Elsevier. This book was released on 2013-10-22 with total page 795 pages. Available in PDF, EPUB and Kindle. Book excerpt: The green alga Chlamydomonas is widely used as an experimental model system for studies in cellular and molecular biology, and in particular plant molecular biology. This book is the only single modern compendium of information on its biology and in particular its molecular biology and genetics. Included in addition to much information on the basic biology is material of a very practical nature, namely, methods for culture, preservation of cultures, preparation of media, lists of inhibitors and other additives to culture media, help with common laboratory problems such as contamination, student demonstrations, and properties of particular strains and mutants. Casual users as well as specialists will find the book to be useful in many ways. - Provides access to previously unpublished data from genetic analysis - Provides descriptions of mutant strains - Depicts summary tables comparing properties of different species and their mutant strains - Explains detailed methods for laboratory procedures of general utility - Furnishes comparisons of culture media - Presents lists of inhibitors, mutagens, and other additives to culture media - Assists with common laboratory problems such as contamination and storage of strains - Demonstrates protocols for laboratory demonstrations available for undergraduate teaching.