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Guide To Signal Pathways In Immune Cells
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Book Synopsis Guide to Signal Pathways in Immune Cells by : E. Nigel Wardle
Download or read book Guide to Signal Pathways in Immune Cells written by E. Nigel Wardle and published by Springer Science & Business Media. This book was released on 2009-04-21 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: To read current biomedical science, one has to have a working knowledge of how important effector molecules cause transduction of their signal within cells, altering the control of genes. This work aims to provide that basic knowledge for medical readers. Students of immunology or cell biology will note its relevance. One will learn how platelets, macrophages, neutrophils, T and B lymphocytes and natural killer cells perform their functions and how skin, breast, prostate and colon cancers emerge. The associated diagrams and tables are used to obviate extensive text. Appropriate references to articles and reviews by workers in each field are given so that further consideration can easily be undertaken. We are all at differing stages of our appreciation of immunology and of pat- physiology. Some persons will have a profound background in biochemistry or molecular biology. Others will have a reminiscence of lectures received years ago. Since this work is principally for clinical doctors, the sections that can be avoided at first reading are marked with an asterisk (*). Always proceed line by line and think of associations that you know. Do you feel comfortable with the statement, “Interleukin 6 stimulates glucose uptake in renal proximal tubular cells, and that action is associated with Stat3, PI3K/Akt, MAPKs and NF-kB signal pathways”? If not, please read on.
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Guide to Signal Pathways in Immune Cells by :
Download or read book Guide to Signal Pathways in Immune Cells written by and published by . This book was released on 2009 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Immunostimulatory DNA Sequences by : E. Raz
Download or read book Immunostimulatory DNA Sequences written by E. Raz and published by Springer Science & Business Media. This book was released on 2001 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a product of a collaborative effort and attempts to provide a wide and up-to-date coverage of information regarding the biology and on the potential application of immunostimulatory DNA. ISS hold great promise for influencing the immune response and the authors anticipate that the high efficacy and low toxicity observed in animal models will translate into success in a variety of human clinical applications.
Book Synopsis Co-signal Molecules in T Cell Activation by : Miyuki Azuma
Download or read book Co-signal Molecules in T Cell Activation written by Miyuki Azuma and published by Springer Nature. This book was released on 2019-11-22 with total page 326 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book equips young immunologists and health professionals with a clear understanding of the fundamental concepts and roles of co-signal molecules and in addition presents the latest information on co-stimulation. The first part of the book is devoted to co-signal molecules and the regulation of T cells. Following an initial overview, subsequent chapters examine each co-signal molecule in turn and discuss the mechanisms by which co-signal molecules regulate the different types of T cell. The second part covers various clinical applications, including in autoimmune disease, neurological disorders, transplantation, graft-versus-host disease, and cancer immunotherapy. To date, co-stimulation blockade and co-inhibition blockade have shown beneficial effects and many additional clinical trials targeting co-signal molecules are ongoing. The mechanisms underlying these successful treatments are explained and the future therapeutic potential in the aforementioned diseases is evaluated. Co-signal Molecules in T Cell Activation will be a valuable reference guide to co-stimulation for basic and clinical researchers in the fields of both immunology and pharmaceutical science.
Book Synopsis Signal Transduction in Cancer by : David A. Frank
Download or read book Signal Transduction in Cancer written by David A. Frank and published by Springer Science & Business Media. This book was released on 2002-12-31 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously. This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents. Series Editor comments: "The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."
Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council
Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.
Book Synopsis Medicinal Mushrooms - A Clinical Guide by : Martin Powell
Download or read book Medicinal Mushrooms - A Clinical Guide written by Martin Powell and published by eBook Partnership. This book was released on 2015-01-22 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: Updated and expanded second edition of the leading reference book on the clinical use of medicinal mushrooms. Written by a biochemist and herbalist with over 20 years' experience of working with medicinal mushrooms, this book provides an in-depth resource for healthcare practitioners. It covers 20 of the most widely used species and contains sections on their use for cancer and other health conditions, as well as discussion of the different formats of mushroom supplement available . 'This really important book is a unique and excellent compilation.' Dr SP Wasser - Editor, International Journal of Medicinal Mushrooms 'This beautifully illustrated book is an invaluable resource on medicinal mushrooms.' Giovanni Maciocia - Author, Foundations of Chinese Medicine 'Easily the most accessible primer on the pharmacology, applications and Chinese medical uses of the top mycological medicinals.' Journal of Chinese Medicine
Download or read book Kuby Immunology written by Jenni Punt and published by Macmillan Higher Education. This book was released on 2018-10-16 with total page 3155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Janis Kuby’s groundbreaking introduction to immunology was the first textbook for the course actually written to be a textbook. Like no other text, it combined an experimental emphasis with extensive pedagogical features to help students grasp basic concepts. Now in a thoroughly updated new edition, Kuby Immunology remains the only undergraduate introduction to immunology written by teachers of the course. In the Kuby tradition, authors Jenni Punt, Sharon Stranford, Patricia Jones, and Judy Owen present the most current topics in an experimental context, conveying the excitement of scientific discovery, and highlight important advances, but do so with the focus on the big picture of the study of immune response, enhanced by unsurpassed pedagogical support for the first-time learner. Punt, Stranford, Jones, and Owen bring an enormous range of teaching and research experiences to the text, as well as a dedication to continue the experiment-based, pedagogical-driven approach of Janis Kuby. For this edition, they have worked chapter by chapter to streamline the coverage, to address topics that students have the most trouble grasping, and to continually remind students where the topic at hand fits in the study of immunology as a whole.
Book Synopsis Biomedical Results from Skylab by : Richard S. Johnston
Download or read book Biomedical Results from Skylab written by Richard S. Johnston and published by . This book was released on 1977 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Signal Transduction by : Lewis C. Cantley
Download or read book Signal Transduction written by Lewis C. Cantley and published by . This book was released on 2014-05-31 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This textbook provides a comprehensive view of signal transduction, covering both the fundamental mechanisms involved and their roles in key biological processes. It first lays out the basic principles of signal transduction, explaining how different receptors receive information and transmit it via signaling proteins, ions, and second messengers. It then surveys the major signaling pathways that operate in cells, before examining in detail how these function in processes such as cell growth and division, cell movement, metabolism, development, reproduction, the nervous system, and immune function"--
Book Synopsis Cell to Cell Signalling by : A. Goldbeter
Download or read book Cell to Cell Signalling written by A. Goldbeter and published by Academic Press. This book was released on 2014-06-28 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cell to Cell Signalling: From Experiments to Theoretical Models is a collection of papers from a NATO Workshop conducted in Belgium in September 1988. The book discusses nerve cells and neural networks involved in signal transfers. The works of Hodgkin and Huxley presents a prototypic combination between experimental and theoretical approaches. The book discusses the coupling process found between secretory cells that modify their behavior. The text also analyzes morphogenesis and development, and then emphasizes the pattern formation found in Drosophila and in the amphibian embryo. The text also cite examples of immunological modeling that is related to the dynamics of immune networks based on idiotypic regulation. One paper analyzes the immune dynamism of HIV infection. The text notes that hormone signaling can be attributed as responsible for intercellular communication. Another paper examines how the dominant follicle in the ovarian cycle is selected, as well as the effectiveness of hormone secretion responsible for encoding the frequency of occurrence of periodic signals. The book also discusses heart signal sources such as cardiac dynamics and the response of periodically excited cardiac cells. The text can prove valuable for practioners in the field of neurology and cardiovascular medicine, and for researchers in molecular biology and molecular chemistry.
Book Synopsis Molecular Biology of B Cells by : Tasuku Honjo
Download or read book Molecular Biology of B Cells written by Tasuku Honjo and published by Academic Press. This book was released on 2014-12-22 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics.
Download or read book MRCOG Part One written by Alison Fiander and published by Cambridge University Press. This book was released on 2016-10-13 with total page 557 pages. Available in PDF, EPUB and Kindle. Book excerpt: A fully updated and illustrated handbook providing comprehensive coverage of all curriculum areas covered by the MRCOG Part 1 examination.
Book Synopsis Disease and the Hippo Pathway by : Carsten Gram Hansen
Download or read book Disease and the Hippo Pathway written by Carsten Gram Hansen and published by MDPI. This book was released on 2019-11-22 with total page 226 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Hippo pathway is a highly dynamic cellular signaling nexus that plays central roles in multiple cell types and regulates regeneration, metabolism, and development. The Hippo pathway integrates mechanotransduction, cell polarity, inflammation, and numerous types of paracrine signaling. If not tightly regulated, dysregulated Hippo pathway signaling drives the onset and progression of a range of diseases, including fibrosis and cancer. The molecular understanding of the Hippo pathway is rapidly evolving. This Special Issue contains ten articles contributed by established and up-and-coming Hippo pathway experts that, as a whole, provides an up-to-date overview of how dysregulated Hippo pathway activity is a common driver of specific diseases. The articles have a particular focus on the underlying molecular and cellular mechanisms that cause the Hippo pathway to go awry, and especially how this drives disease. The articles analyze disease-specific as well as common themes, which provides valuable insights into the fundamental molecular mechanisms in the dysfunctioning Hippo pathway, and thereby offer practical insights into potential future therapeutic intervention strategies.
Author :Alasdair M. Gilfillan Publisher :Springer Science & Business Media ISBN 13 :1441995331 Total Pages :312 pages Book Rating :4.4/5 (419 download)
Book Synopsis Mast Cell Biology by : Alasdair M. Gilfillan
Download or read book Mast Cell Biology written by Alasdair M. Gilfillan and published by Springer Science & Business Media. This book was released on 2011-06-28 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The editors of Mast Cell Biology, Drs. Gilfillan and Metcalfe, have enlisted an outstanding group of investigators to discuss the emerging concepts in mast cell biology with respect to development of these cells, their homeostasis, their activation, as well as their roles in maintaining health on the one hand and on the other, their participation in disease.
Book Synopsis A Guide to Evidence-based Integrative and Complementary Medicine by : Vicki Kotsirilos
Download or read book A Guide to Evidence-based Integrative and Complementary Medicine written by Vicki Kotsirilos and published by Elsevier Health Sciences. This book was released on 2011-01-25 with total page 973 pages. Available in PDF, EPUB and Kindle. Book excerpt: The must-have integrative and complementary medicine reference from experts in the field This exhaustive textbook is ideal for anyone with an interest in integrative and complementary medicine in Australia; including General Practitioners, medical students, integrative clinicians and health practitioners. A Guide to Evidence-based Integrative and Complementary Medicine presents non-pharmacologic treatments for common medical practice complaints – all supported by current scientific evidence. These include Attention Deficit Hyperactivity Disorder (ADHD), asthma, insomnia, anxiety, depression and many more. This practical health resource profiles myriad approaches in integrative and complementary medicine, such as mind-body medicine, stress management techniques, dietary guidelines, exercise and sleep advice, acupuncture, nutritional medicine, herbal medicine, and advice for managing lifestyle and behavioural factors. It also looks at complementary medicines that may impact the treatment of disease. A Guide to Evidence-based Integrative and Complementary Medicine contains only proven therapies from current research, particularly Cochrane reviews, systematic reviews, randomised control trials, published cohort studies and case studies. • easy access to evidence-based clinical data on non-pharmacological treatments – including complementary medicines – for common diseases and conditions • instant advice on disease prevention, health promotion and lifestyle issues• chapter summaries based on scientific evidence using the NHMRC guidelines grading system• printable patient summary sheets at chapter end to facilitate discussion of clinical management• conveniently organised by common medical presentations
