Read Books Online and Download eBooks, EPub, PDF, Mobi, Kindle, Text Full Free.
Genome Mining And Marine Microbial Natural Products
Download Genome Mining And Marine Microbial Natural Products full books in PDF, epub, and Kindle. Read online Genome Mining And Marine Microbial Natural Products ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!
Book Synopsis Genome Mining and Marine Microbial Natural Products by : Kui Hong
Download or read book Genome Mining and Marine Microbial Natural Products written by Kui Hong and published by MDPI. This book was released on 2020-01-07 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two review papers, eight research articles, and one brief report were published in this Special Issue. They showed the rich resources that are present within the genomes of marine microorganisms and discussed the use of recently developed tools and technologies to exploit this genetic richness. Examples include the rational supply of precursors according to the relevant biosynthetic pathway and stress driven discovery together with the use of histone deacetylase inhibitors to facilitate the discovery of new bioactive molecules with potential biopharmaceutical applications. We believe that the content of this Special Issue reflects the current state-of-the-art research in this area and highlights the interesting strategies that are being employed to uncover increasing numbers of exciting novel compounds for drug discovery from marine genetic resources.
Book Synopsis Genome Mining and Marine Microbial Natural Products by : Alan Dobson
Download or read book Genome Mining and Marine Microbial Natural Products written by Alan Dobson and published by . This book was released on 2020 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: Two review papers, eight research articles, and one brief report were published in this Special Issue. They showed the rich resources that are present within the genomes of marine microorganisms and discussed the use of recently developed tools and technologies to exploit this genetic richness. Examples include the rational supply of precursors according to the relevant biosynthetic pathway and stress driven discovery together with the use of histone deacetylase inhibitors to facilitate the discovery of new bioactive molecules with potential biopharmaceutical applications. We believe that the content of this Special Issue reflects the current state-of-the-art research in this area and highlights the interesting strategies that are being employed to uncover increasing numbers of exciting novel compounds for drug discovery from marine genetic resources.
Book Synopsis Genome Mining and Synthetic Biology in Marine Natural Products Discovery by : Maria Costantini
Download or read book Genome Mining and Synthetic Biology in Marine Natural Products Discovery written by Maria Costantini and published by MDPI. This book was released on 2021-09-03 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, marine genomics has become a rapidly growing field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome Mining and Synthetic Biology in Marine Natural Product Discovery” aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term “genome mining” is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth’s surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic “Blue Growth”, with the urgent goal of discovering new drugs.
Book Synopsis Natural Product Genomics and Metabolomics of Marine Bacteria by :
Download or read book Natural Product Genomics and Metabolomics of Marine Bacteria written by and published by . This book was released on 2022-02-24 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Natural Product Genomics and Metabolomics of Marine Bacteria by : Max Crüsemann
Download or read book Natural Product Genomics and Metabolomics of Marine Bacteria written by Max Crüsemann and published by . This book was released on 2022 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Marine organisms are a treasure trove for the discovery of novel natural products, and, thus, marine natural products have been a focus of interest for researchers for decades. Some marine bacteria are prolific producers of natural products, occurring either free-living or, as recently shown, in symbiosis with marine animals. Recent advances in DNA sequencing have led to an enormous increase in published bacterial genomes and bioinformatics tools to analyze natural product biosynthetic potential by various "genome mining" approaches. Similarly, analytical NMR and MS methods for the characterization and comparison of metabolomes of natural product producers have advanced. Novel interdisciplinary approaches combine genomics and metabolomics data for accelerated and targeted natural product discovery. This Special Issue invites articles from both genomics- and metabolomics-driven studies on marine bacteria with a focus on natural product discovery and characterization. We particularly welcome articles that combine genomics and metabolomic approaches for the dereplication and characterization of marine bacterial natural products.
Book Synopsis Genome Mining and Synthetic Biology in Marine Natural Products Discovery by : Maria Costantini
Download or read book Genome Mining and Synthetic Biology in Marine Natural Products Discovery written by Maria Costantini and published by . This book was released on 2021 with total page 92 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, marine genomics has become a growning rapidly field, helped by the large amount of information that is becoming available to the international scientific community. Taking into account the current excitement in the field of marine biotechnology, this Special Issue entitled “Genome Mining and Synthetic Biology in Marine Natural Product Discovery” aims to to assess the impact of these molecular approaches on the discovery of bioactive compounds from marine organisms. The term “genome mining” is used to identify all bioinformatic investigations aimed at detecting the biosynthetic pathways of bioactive natural products and their possible functional and chemical interactions. Several studies are now reporting on marine organisms. Oceans cover nearly 70% of the Earth's surface and host a huge ecological, chemical, and biological diversity. The natural conditions of the sea favor, in marine organisms, the production of a large variety of novel molecules with great pharmaceutical potential. Marine organisms are unique in their structural and functional features compared to terrestrial ones. Innovation in this field is very rapid, as revealed by the funding of several Seventh Framework Programme (FP7) and Horizon 2020 projects under the topic “Blue Growth”, with the urgent goal of discovering new drugs.
Book Synopsis Marine Biotechnology in the Twenty-First Century by : National Research Council
Download or read book Marine Biotechnology in the Twenty-First Century written by National Research Council and published by National Academies Press. This book was released on 2002-05-29 with total page 130 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dramatic developments in understanding the fundamental underpinnings of life have provided exciting opportunities to make marine bioproducts an important part of the U.S. economy. Several marine based pharmaceuticals are under active commercial development, ecosystem health is high on the public's list of concerns, and aquaculture is providing an ever greater proportion of the seafood on our tables. Nevertheless, marine biotechnology has not yet caught the public's, or investor's, attention. Two workshops, held in October 1999 and November 2001 at the National Academies, were successful in highlighting new developments and opportunities in environmental and biomedical applications of marine biotechnology, and also in identifying factors that are impeding commercial exploitation of these products. This report includes a synthesis of the 2001 sessions addressing drug discovery and development, applications of genomics and proteomics to marine biotechnology, biomaterials and bioengineering, and public policy and essays contributed by the workshop speakers.
Book Synopsis Marine Microbial Diversity as a Source of Bioactive Natural Products by : Didier Stien
Download or read book Marine Microbial Diversity as a Source of Bioactive Natural Products written by Didier Stien and published by MDPI. This book was released on 2020-06-17 with total page 146 pages. Available in PDF, EPUB and Kindle. Book excerpt: A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign that marine fungi have been under studied to date and are perceived by many researchers as an important source of discovery in this field. A best practices guide for the isolation of marine fungi from different matrixes and their conservation is also presented. The comparison of the phylogenetic and metabolomic profiles of microalgae from different lineages provides novel insights into the potential of chemotaxonomy in marine phytoplankton, showing a good overlap of phylogenetic and chemotaxonomic signals.
Book Synopsis Drug Discovery from Natural Products by : Olga Genilloud
Download or read book Drug Discovery from Natural Products written by Olga Genilloud and published by Royal Society of Chemistry. This book was released on 2012 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: An integrated review of the most recent trends in natural products, drug discovery, and key lead candidates that are outstanding for their chemistry and biology in novel drug development.
Book Synopsis Marine Cyanobacteria by : Loïc Charpy
Download or read book Marine Cyanobacteria written by Loïc Charpy and published by Musee Oceanographique. This book was released on 1999 with total page 644 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Modern Biocatalysis by : Gavin Williams
Download or read book Modern Biocatalysis written by Gavin Williams and published by Royal Society of Chemistry. This book was released on 2018-05-31 with total page 594 pages. Available in PDF, EPUB and Kindle. Book excerpt: The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Book Synopsis Microbial Resources by : Ipek Kurtböke
Download or read book Microbial Resources written by Ipek Kurtböke and published by Academic Press. This book was released on 2017-03-31 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics Provides information on the utilization of microbial resources in biotechnology Covers legislative issues and related law in biodiscovery Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications
Book Synopsis Natural Products from Marine Microorganisms by : Xian-Wen Yang
Download or read book Natural Products from Marine Microorganisms written by Xian-Wen Yang and published by Frontiers Media SA. This book was released on 2020-01-22 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt: Natural products continue to serve as sources for the development of new medicines. There is currently a revival of interest in the discovery of bioactive compounds with new chemical structures from natural sources, largely due to the fact that synthetic libraries have not yielded the expected number of developmental candidates in the pharmaceutical industry during the last decade. In addition, the emergence of clinically relevant pathogens that are becoming increasingly resistant to currently used medicines strengthens the notion that natural product research is urgently required. Considering the fact that almost 10% of bioactive compounds are of microbial origin, and that marine microorganisms are relatively poorly studied compared to their terrestrial relatives, marine microorganisms are regarded as the most potential-laden resource for drug discovery.
Book Synopsis Chemical Biology of Natural Products by : David J. Newman
Download or read book Chemical Biology of Natural Products written by David J. Newman and published by CRC Press. This book was released on 2017-09-22 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Biology of Natural Products This unique, long-awaited volume is designed to address contemporary aspects of natural product chemistry and its influence on biological systems, not solely on human interactions. The subjects covered include discovery, isolation and characterization, biosynthesis, biosynthetic engineering, pharmaceutical, and other applications of these compounds. Each chapter begins with a brief and simple introduction to the subject matter, and then proceeds to guide the reader towards the more contemporary, cutting-edge research in the field, with the contributing authors presenting current examples from their own work in order to exemplify key themes. Topics covered in the text include genome mining, heterologous expression, natural product synthesis, biosynthesis, glycosylation, chemical ecology, and therapeutic applications of natural products, both current and potential.
Book Synopsis Natural Products Isolation by : Satya D. Sarker
Download or read book Natural Products Isolation written by Satya D. Sarker and published by Springer Science & Business Media. This book was released on 2008-02-05 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term “natural products” spans an extremely large and diverse range of chemical compounds derived and isolated from biological sources. Our interest in natural products can be traced back thousands of years for their usefulness to humankind, and this continues to the present day. Compounds and extracts derived from the biosphere have found uses in medicine, agriculture, cosmetics, and food in ancient and modern societies around the world. Therefore, the ability to access natural products, understand their usefulness, and derive applications has been a major driving force in the field of natural product research. The first edition of Natural Products Isolation provided readers for the first time with some practical guidance in the process of extraction and isolation of natural products and was the result of Richard Cannell’s unique vision and tireless efforts. Unfortunately, Richard Cannell died in 1999 soon after completing the first edition. We are indebted to him and hope this new edition pays adequate tribute to his excellent work. The first edition laid down the “ground rules” and established the techniques available at the time. Since its publication in 1998, there have been significant developments in some areas in natural product isolation. To capture these developments, publication of a second edition is long overdue, and we believe it brings the work up to date while still covering many basic techniques known to save time and effort, and capable of results equivalent to those from more recent and expensive techniques.
Book Synopsis Drug Discovery from Natural Products by : Olga Genilloud
Download or read book Drug Discovery from Natural Products written by Olga Genilloud and published by Royal Society of Chemistry. This book was released on 2012-08-21 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology as a starting point in novel drug development. The authors focus on different trends that are and will continue to be impacting multiples stages of modern drug discovery from NPs that have not been included in other works. This is complemented with a series of case studies from leading experts from industry and academia on key molecules and derivatives that have been chosen for their novelty in chemistry, biology and clinical applications. The book intends to reflect the current confluence of different disciplines in chemical biology and synthetic chemistry supported by a more profound knowledge of systems biology that ensures the concurrency and synergisms of expertise from different research fields that impact in the discovery of novel molecules. In the first section the chapters reflect recent approaches to exploit the biosynthetic potential of microbial resources (including genome mining, metagenomic and epigenetic approaches), as well as biosynthetic chemistry tools to respond to product supply and novel screening alternatives that have lead to the discovery of novel chemistry. The second part reviews, in the form of case studies, some examples of bioactive molecules in the important therapeutic areas of antiinfectives, oncology and antiparasitics.
Book Synopsis Natural Products from Actinomycetes by : Ravishankar V. Rai
Download or read book Natural Products from Actinomycetes written by Ravishankar V. Rai and published by Springer Nature. This book was released on 2022-04-15 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides in-depth information about the ecology, diversity and applications of Actinomycetes. The book is divided into two major parts. The first part discusses the diversity, chemical biology and ecology of Actinomycetes. It also covers the discovery of natural products from soil, endophytic and marine-derived Actinomycetes. It includes natural product discovery, chemical biology, new methods for discovering secondary metabolites, structure elucidation and biosynthetic research of natural products. The chapters in this part focus on the effects of biological and chemical elicitation at molecular level on secondary metabolism in Actinomycetes. The second part of the book discusses genomic and synthetic biology approaches in Actinomycetes drug discovery. This part includes chapters focused on the application of metabolic engineering to optimize natural product synthesis and the use of omics data in engineering of regulatory genes. It covers the advanced tools of synthetic biology and metabolic engineering including cluster assembly, CRISPR/Cas9 technologies, and chassis strain development for natural product overproduction in Actinomycetes. It describes the use of bioinformatics tools for reprogramming of biosynthetic pathways through polyketide synthase and non-ribosomal peptide synthetase engineering. These advanced genomic and molecular tools are expected to accelerate the discovery and development of new natural products from Actinomycetes with medicinal and other industrial applications. The book is useful to researchers and students in the field of microbiology, pharmaceutical sciences and drug discovery.
