Neuropsychiatric Disorders and Epigenetics

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Publisher : Academic Press
ISBN 13 : 9780443185168
Total Pages : 0 pages
Book Rating : 4.1/5 (851 download)

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Book Synopsis Neuropsychiatric Disorders and Epigenetics by : Jacob Peedicayil

Download or read book Neuropsychiatric Disorders and Epigenetics written by Jacob Peedicayil and published by Academic Press. This book was released on 2023-09-28 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy.

Epigenetics in Psychiatry

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Publisher : Academic Press
ISBN 13 : 0128235780
Total Pages : 848 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Epigenetics in Psychiatry by : Jacob Peedicayil

Download or read book Epigenetics in Psychiatry written by Jacob Peedicayil and published by Academic Press. This book was released on 2021-08-21 with total page 848 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth. Fully revised to discuss new areas of research across neuronal stem cells, cognitive disorders, and transgenerational epigenetics in psychiatric disease Relates broad advances in psychiatric epigenetics to a modern understanding of the genome, transcriptome, and proteins Catalyzes knowledge discovery in both basic epigenetic biology and epigenetic targets for drug discovery Provides guidance in research methods and protocols, as well how to employ data from consortia, single cell analysis, and epigenome-wide association studies (EWAS) Features chapter contributions from international leaders in the field

Genetics and Epigenetics of Psychiatric Diseases - Volume II

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2832506062
Total Pages : 127 pages
Book Rating : 4.8/5 (325 download)

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Book Synopsis Genetics and Epigenetics of Psychiatric Diseases - Volume II by : Cunyou Zhao

Download or read book Genetics and Epigenetics of Psychiatric Diseases - Volume II written by Cunyou Zhao and published by Frontiers Media SA. This book was released on 2022-11-16 with total page 127 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epigenetics and Psychiatric Disease

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Author :
Publisher : Academic Press
ISBN 13 : 0128135662
Total Pages : 450 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Epigenetics and Psychiatric Disease by :

Download or read book Epigenetics and Psychiatric Disease written by and published by Academic Press. This book was released on 2018-06-22 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics and Psychiatric Disease, Volume 157, the latest volume in the Progress in Molecular Biology and Translational Science series, includes recent developments on a variety of topics, including the Epigenetic landscapes of the adversity-exposed brain, Chromosomal conformations and epigenomic regulation in schizophrenia, Progress in the epigenetics of depression, the epigenetics of circadian rhythms in imprinted neurodevelopmental disorders, DNA methylation mediating substance abuse, mechanisms and therapeutic opportunities, DNA methylation in animals model of psychosis, Epigenetics of early life stress, Epigenetic drugs for mood disorders, and more. Accessible to students and researchers alike, with content that appeals to a variety of readers Written by leading authorities in their respective fields of molecular biology

Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition

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Publisher : Frontiers Media SA
ISBN 13 : 2889660257
Total Pages : 205 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition by : Cunyou Zhao

Download or read book Genetics and Epigenetics of Psychiatric Diseases, 2nd Edition written by Cunyou Zhao and published by Frontiers Media SA. This book was released on 2020-10-09 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatric diseases have a highly complex etiology, aggregating in families but not segregating in a traditional Mendelian manner. Recent approaches to understanding the causes of psychiatric disease have focused on describing the genetic contribution to major psychiatric illnesses; the use of large-scale genome-wide association studies (GWAS) and exome sequencing has enabled a systematic exploration of genetic risk factors and identified over 100 independent genomic loci significantly associated with psychiatric diseases; however, there remains uncertainty about the causal genes involved in disease pathogenesis, and how their function is regulated. Since many GWAS variants reside in non-coding regions, the disease-associated common variants might be enriched in regulatory domains, including enhancers and regions of active chromatin state. These lead us to focus on the possible role of non-sequence-based genomic variation in health and disease. Of particular interest are epigenetic modifications that regulate gene expression through modifications to DNA, RNA, histone proteins, and chromatin. The availability of high-throughput profiling methods for quantifiying epigenomic modifications in large numbers of samples has enabled us to perform epigenome-wide association studies (EWAS) aimed at screening methylomic variations associated with environmental exposure and disease. Thus systematic integration of genetic, epigenetic and epidemiological approaches will contribute to improving our understanding of the molecular mechanisms underlying disease phenotypes.

Principles of Psychiatric Genetics

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Publisher : Cambridge University Press
ISBN 13 : 0521896495
Total Pages : 415 pages
Book Rating : 4.5/5 (218 download)

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Book Synopsis Principles of Psychiatric Genetics by : John I. Nurnberger

Download or read book Principles of Psychiatric Genetics written by John I. Nurnberger and published by Cambridge University Press. This book was released on 2012-09-13 with total page 415 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.

Epigenetics of Stress and Stress Disorders

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Publisher : Academic Press
ISBN 13 : 0128230622
Total Pages : 422 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Epigenetics of Stress and Stress Disorders by : Nagy Youssef

Download or read book Epigenetics of Stress and Stress Disorders written by Nagy Youssef and published by Academic Press. This book was released on 2022-02-18 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics of Stress and Stress Disorders, a new volume in the Translational Epigenetics series, examines the epigenetic mechanisms involved in modifying DNA following prolonged stress or trauma. This is accomplished through the evaluation of both the physiological and molecular effects of stress on the body that can eventually lead to stress disorders. The book begins by providing a psychiatric, biological, and phenomenological foundation for understanding stress disorders, before delving into the genomics of stress disorders. From here, chapter authors discuss a range of recent epigenetic research in the area, highlighting epigenome-wide association studies (EWAS), exciting developments in noncoding RNA studies, possible effects of prolonged stress on telomere shortening, and the long-term physical effects of PTSD on the health of patients. The book also examines the effect of adversity during sensitive periods or development and across the life span. The book concludes by looking at possible transgenerational stress-induced epigenetic alterations on future offspring and important areas of research for public health, along with the potential for epigenetic therapeutics or “epidrugs. Examines the epigenetics of stress, trauma, and related stress disorders Connects new research to clinical practice and highlights implications for patient care, drug discovery, and public health Discusses the epigenetic effect of adversity across the life span, and transgenerational stress-induced epigenetic alterations Features chapter contributions from international experts in the field

Epigenetics

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Publisher : SelectBooks, Inc.
ISBN 13 : 1590792556
Total Pages : 443 pages
Book Rating : 4.5/5 (97 download)

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Book Synopsis Epigenetics by : Joel D. Wallach

Download or read book Epigenetics written by Joel D. Wallach and published by SelectBooks, Inc.. This book was released on 2014-05 with total page 443 pages. Available in PDF, EPUB and Kindle. Book excerpt: WHAT IS EPIGENETICS? Epigenetics is an emerging field of science that studies alterations in gene expression caused by factors other than changes in the DNA sequence. Epigenetics: The Death of the Genetic Theory of Disease Transmission is the result of decades of research and its findings that could be as critical to our understanding of human health as Pasteur’s research in bacteriology. Dr. Joel “Doc” Wallach has dedicated his life work to identifying connections between certain nutritional deficiencies and a range of maladies, formerly thought to be hereditary, including Cystic Fibrosis and Muscular Dystrophy. This nexus between nutrition and so-called genetic disease has been observed in both humans and primates, and it is the central theme of Epigenetics. To bring us Epigenetics, Wallach has teamed with noted scholars Dr. Ma Lan and Dr. Gerhard N. Schrauzer. Their collective expertise gives this book its far reaching perspective. Epigenetics is of vital importance to anyone who wants real knowledge about how the human body functions, and it provides a path for better health. Epigentics dispels the dogma and misinformation propagated by medical institutions and doctors resistant to change. Epigenetics is the beginning of a new era of well-being on this planet.

The International Handbook on Psychopathic Disorders and the Law

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Publisher : John Wiley & Sons
ISBN 13 : 0470011858
Total Pages : 662 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis The International Handbook on Psychopathic Disorders and the Law by : Alan Felthous

Download or read book The International Handbook on Psychopathic Disorders and the Law written by Alan Felthous and published by John Wiley & Sons. This book was released on 2008-03-10 with total page 662 pages. Available in PDF, EPUB and Kindle. Book excerpt: The economic impact of society’s efforts to rehabilitate and contain psychopathically disordered individuals can be enormous. Understanding these disorders, developing valid assessment methods and providing safe, effective treatments is therefore of paramount importance. Reflecting the work of a truly international panel of experts from Europe, North America and Asia, the International Handbook on Psychopathic Disorders and the Law offers an in-depth, multidisciplinary look at key aspects of the development and etiology of psychopathic disorders, current methods of intervention, treatment and management, and how these disorders impact decision-making in civil and criminal law.

Stress: Genetics, Epigenetics and Genomics

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Publisher : Academic Press
ISBN 13 : 0128131578
Total Pages : 346 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Stress: Genetics, Epigenetics and Genomics by : George Fink

Download or read book Stress: Genetics, Epigenetics and Genomics written by George Fink and published by Academic Press. This book was released on 2020-10-24 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases.The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier’s Encyclopedia of Stress (2000 and 2007). Volume 4 is ideal for graduate students, post-doctoral fellows, faculty and clinicians interested in stress genetics, epigenetics and genomics involved in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry and the social sciences Articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field, with each chapter fully vetted for reliable expert knowledge Richly illustrated with explanatory figures and tables Each chapter includes a boxed “Key points call out section Affordably priced, self-contained volume for readers specifically interested in stress genetics and epigenetics, removing the need to purchase the whole Handbook series

Epigenetics

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Publisher : CSHL Press
ISBN 13 : 0879697245
Total Pages : 503 pages
Book Rating : 4.8/5 (796 download)

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Book Synopsis Epigenetics by : C. David Allis

Download or read book Epigenetics written by C. David Allis and published by CSHL Press. This book was released on 2007 with total page 503 pages. Available in PDF, EPUB and Kindle. Book excerpt: The regulation of gene expression in many biological processes involves epigenetic mechanisms. In this new volume, 24 chapters written by experts in the field discuss epigenetic effects from many perspectives. There are chapters on the basic molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of organisms in which it has been most studied. Thus, there are chapters on histone and DNA methylation, siRNAs and gene silencing; X-chromosome inactivation, dosage compensation and imprinting; and discussion of epigenetics in microbes, plants, insects, and mammals. The last part of the book looks at how epigenetic mechanisms act in cell division and differentiation, and how errors in these pathways contribute to cancer and other human diseases. Also discussed are consequences of epigenetics in attempts to clone animals. This book is a major resource for those working in the field, as well as being a suitable text for advanced undergraduate and graduate courses on gene regulation.

The Epigenetics Revolution

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Publisher : Columbia University Press
ISBN 13 : 0231530714
Total Pages : 353 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis The Epigenetics Revolution by : Nessa Carey

Download or read book The Epigenetics Revolution written by Nessa Carey and published by Columbia University Press. This book was released on 2012-03-06 with total page 353 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Epigenetic Mechanisms of Gene Regulation

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Publisher :
ISBN 13 :
Total Pages : 716 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Epigenetic Mechanisms of Gene Regulation by : Vincenzo E. A. Russo

Download or read book Epigenetic Mechanisms of Gene Regulation written by Vincenzo E. A. Russo and published by . This book was released on 1996 with total page 716 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many inheritable changes in gene function are not explained by changes in the DNA sequence. Such epigenetic mechanisms are known to influence gene function in most complex organisms and include effects such as transposon function, chromosome imprinting, yeast mating type switching and telomeric silencing. In recent years, epigenetic effects have become a major focus of research activity. This monograph, edited by three well-known biologists from different specialties, is the first to review and synthesize what is known about these effects across all species, particularly from a molecular perspective, and will be of interest to everyone in the fields of molecular biology and genetics.

The American Psychiatric Association Publishing Textbook of Mood Disorders

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Publisher :
ISBN 13 : 9781615374526
Total Pages : pages
Book Rating : 4.3/5 (745 download)

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Book Synopsis The American Psychiatric Association Publishing Textbook of Mood Disorders by : Charles B. Nemeroff

Download or read book The American Psychiatric Association Publishing Textbook of Mood Disorders written by Charles B. Nemeroff and published by . This book was released on 2023 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "The second edition of The American Psychiatric Association Publishing Textbook of Mood Disorders is a book for a new generation of clinicians, trainees, and educators. Much has changed in the field of mood disorders in the 16 years since the first edition, and this new edition ably covers these changes, introducing new chapters on the epigenetics of mood disorders; the role of the immune system in these disorders; the contribution of childhood maltreatment to mood disorder risk, illness course, and treatment response; the management of treatment-resistant depression; and the emergence of promising investigational agents (most notably, ketamine and its relatives) with novel mechanisms of action in depression. Under new editorial direction and with a revised roster of expert contributors, The American Psychiatric Publishing Textbook of Mood Disorders, Second Edition, provides an authoritative, comprehensive, and evidence-based synthesis of current knowledge in the multifaceted field of mood disorders"--

Epigenetics in Biology and Medicine

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Publisher : CRC Press
ISBN 13 : 1000654206
Total Pages : 260 pages
Book Rating : 4.0/5 (6 download)

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Book Synopsis Epigenetics in Biology and Medicine by : Manel Esteller

Download or read book Epigenetics in Biology and Medicine written by Manel Esteller and published by CRC Press. This book was released on 2008-09-17 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Anomalous epigenetic patterns touch many areas of study including biomedical, scientific, and industrial. With perspectives from international experts, this resource offers an all-inclusive overview of epigenetics, which bridge DNA information and function by regulating gene expression without modifying the DNA sequence itself. Epigenetics, in its

Epigenetic Epidemiology

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Publisher : Springer Science & Business Media
ISBN 13 : 9400724950
Total Pages : 450 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Epigenetic Epidemiology by : Karin B. Michels

Download or read book Epigenetic Epidemiology written by Karin B. Michels and published by Springer Science & Business Media. This book was released on 2012-01-02 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored.This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics!

The Developing Genome

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Publisher : Oxford University Press, USA
ISBN 13 : 0199922349
Total Pages : 321 pages
Book Rating : 4.1/5 (999 download)

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Book Synopsis The Developing Genome by : David Scott Moore

Download or read book The Developing Genome written by David Scott Moore and published by Oxford University Press, USA. This book was released on 2015 with total page 321 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes bibliographical references (pages 275-300) and index