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Author :
Publisher :
ISBN 13 :
Total Pages : 648 pages
Book Rating : 4.3/5 (91 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page 648 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.:/5 (963 download)
Download or read book Genetic concepts and neoplasia written by and published by . This book was released on 1970 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.:/5 (7 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 68 pages
Book Rating : 4.:/5 (1 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1969 with total page 68 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.:/5 (876 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.:/5 (876 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Genetic Concepts and Neoplasia- a Collection of Papers Presented at the 23rd Annual Symposium on Fundamental Cancer Research written by and published by . This book was released on with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 620 pages
Book Rating : 4.:/5 (876 download)
Download or read book Genetic Concepts and Neoplasia written by and published by . This book was released on 1970 with total page 620 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : R.S. Verma
Publisher : Elsevier
ISBN 13 : 0080526160
Total Pages : 233 pages
Book Rating : 4.0/5 (85 download)
Download or read book Genetics of Human Neoplasia, Part A written by R.S. Verma and published by Elsevier. This book was released on 1995-09-25 with total page 233 pages. Available in PDF, EPUB and Kindle. Book excerpt: The underlying idea that cancer is a genetic disease at the cellular level was postulated over 75 years ago when Boveri hypothesised that the malignant cell was one that had obtained an abnormal chromatin content. However, it has been only the last decade where enormous strides have been made toward understanding neoplastic development. Explosive growth in the discipline of cancer genetics is so rapid that any attempt to review this subject becomes rapidly outdated and continuous revisions are warranted. Conclusive evidence has been reached associating specific chromosomal abnormalities to various cancers. We have just begun to characterise the genes, which are involved in these consistent chromosomal rearrangements resulting in the elucidation of the mechanisms of neoplastic transformation at a molecular level. The identification of over 50 oncogenes has led to a better understanding of the physiological process. Tumor suppresser genes, which were discovered through inheritance mechanisms, have further shed some light towards understanding the loss of heterozygosity during carcinogenesis. The message emerging with increasing clarity concerning specific pathways which regulate the fundamental process of cell division and uncontrolled growth. The advances in molecular biology have led to a major insight in establishing precise diagnosis and treatment of many cancers resulting in prevention of death. The field is expanding so rapidly that a complete account of all aspects of genetics of cancer could not be accommodated within the scope of a single volume format. Nevertheless, a few very specific topics have been chosen, which readers may find of great interest in hopes that their interest may be rejuvenated concerning the bewildering nature of this deadly disease. The contributors to Volume 3 have provided up-to-date accounts of their fields of expertise. Although the contributors have kept their chapters brief, they include an extensive bibliography for those who wish to understand a particular topic in depth. For more than a century, cancer has been diagnosed on the enigmatic basis of morphological features. Establishing a diagnosis based on DNA, RNA, and proteins, which is done routinely now, was once inconceivable. Cloning a gene of hematopoietic origin is no longer a fantasy. The approach has shifted over the past 15 years from identification of chromosomal abnormalities toward zeroing in on cancer genes.
Author : Fred Bunz
Publisher : Springer Science & Business Media
ISBN 13 : 1402067844
Total Pages : 333 pages
Book Rating : 4.4/5 (2 download)
Download or read book Principles of Cancer Genetics written by Fred Bunz and published by Springer Science & Business Media. This book was released on 2007-12-20 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. Focused on the most highly representative genes that underlie the most common cancers, the book is aimed at advanced undergraduates who have completed introductory courses in genetics, biology and biochemistry, medical students, and house medical house staff preparing for board examinations. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand.
Author : Henry T. Lynch
Publisher : Springer Science & Business Media
ISBN 13 : 3642759939
Total Pages : 237 pages
Book Rating : 4.6/5 (427 download)
Download or read book Recent Progress in the Genetic Epidemiology of Cancer written by Henry T. Lynch and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 237 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discipline of genetic epidemiology pertains to the vertical transmission of the susceptibility (predisposition) to a complex disease in a structured population. This statement meets halfway 1 the broad definitiongiven by N. E. Morton and S. c. Chung in 1978 2 and the concise one given by M. -C. King et al. in 1984. 1t pinpoints the fundamental genetic hypothesis, namely, the existence of an inherited condition that predisposes an individual to a specific disease, and the corresponding subject ofinvestigation, the family. Thus, the genetic epidemiological situation consists of three basic elements: (l) the genealogical structure, (2) the mode of inherit ance (i. e. , the "genetic model") for the trait of interest, and (3) the observable phenotypes of susceptibility. It is clear that genetic epidemiology is a research field posi tioned at the intersection of molecular genetics, population gen etics, and clinical genetics. Perhaps the genealogical tree should be its central element: it evidences something forgotten in mole cular genetics, namely the relationships, and associations with probabilistic and statistical concepts from population genetics. It offers a structure and a "history" for those clinicians studying familial diseases who are searching for genetic determinants of susceptibility. The genetic epidemiologist begins his analysis with a point on this genealogical tree, namely the proband, and attempts to carry out (nonrandom) "ascertainment sampling" by using a strategy that depends on the form and dimension (extended pedigrees versus nuclear families) of the tree.
Author : Sue Clark,
Publisher : tfm Publishing Limited
ISBN 13 : 1908986336
Total Pages : 257 pages
Book Rating : 4.9/5 (89 download)
Download or read book A Guide to Cancer Genetics in Clinical Practice written by Sue Clark, and published by tfm Publishing Limited. This book was released on 2009-05-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: FIRST PRIZE Winner in the Oncology category of the 2010 BMA Medical Book Competition. Intensive research over the last fifteen years has yielded a vast expansion in our understanding of the role of inheritance and genetics in a variety of cancers. Several inherited conditions have been identified which result in a high risk of various cancers; some of these were previously recognized, but the genetic basis underlying them has now been elucidated. This knowledge is now entering the sphere of routine clinical care. Surgeons, gastroenterologists, gynaecologists, oncologists, endocrinologists and many others need an awareness of these disorders, an understanding of genetic testing and when it is indicated, and how to manage patients with inherited cancer predisposition and their families. This book covers the basic concepts of cancer genetics. The common inherited cancer syndromes are each dealt with in greater depth, with the current management outlined. This book is aimed at all clinicians who may encounter these conditions in their practice. It aims to facilitate identification of high-risk individuals and families, to inform interaction with geneticists and other subspecialists, to provide a basis for patient management and to stimulate interest in these fascinating conditions.
Author : Xin Wei Wang
Publisher : Springer Science & Business Media
ISBN 13 : 1441960821
Total Pages : 390 pages
Book Rating : 4.4/5 (419 download)
Download or read book Molecular Genetics of Liver Neoplasia written by Xin Wei Wang and published by Springer Science & Business Media. This book was released on 2010-11-08 with total page 390 pages. Available in PDF, EPUB and Kindle. Book excerpt: Primary liver cancer is the third most deadly and fifth most common cancer worldwide (~500,000 deaths annually), with a sharp increase of incidence in the United States in recent years. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major types of primary liver cancer. Risk factors include gender, hepatitis B virus (HBV), hepatitis C virus (HCV), cirrhosis, metabolism diseases, diabetes, obesity, toxins, excess alcohol consumption and smoking. Liver cancer arises most frequently in inflammatory livers with extensive oxidative stress due to viral hepatitis which causes over 80% of HCC cases worldwide. Currently, survival remains dismal for most HCC and CC patients, largely due to the tumor’s aggressiveness at the time of diagnosis and the lack of effective therapy.
Author : Suzanne M. Mahon
Publisher :
ISBN 13 : 9781635930498
Total Pages : 0 pages
Book Rating : 4.9/5 (34 download)
Download or read book Understanding Genomic and Hereditary Cancer Risk written by Suzanne M. Mahon and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Collecting a family medical history is a regular component of the nursing assessment process that often includes information on familial cancer diagnoses, and patients may fear that they or their loved ones might be at increased risk for developing cancer because of hereditary factors. Although true inherited risk for developing cancer is much less common than acquired risk for developing cancer, approximately 10% of cancer diagnoses can be attributed to inherited risk. The identification of families exhibiting hereditary cancer syndromes enables individuals at risk to engage in increased surveillance and, in some cases, risk-reducing surgery and other preventive measures, which ultimately lead to decreasing the morbidity and mortality associated with a cancer diagnosis. The role of the nurse in helping patients to understand and manage hereditary cancer risk requires specialized knowledge of genetics and genomics concepts. Understanding Genomic and Hereditary Cancer Risk: A Handbook for Oncology Nurses provides background on basic genetic and genomic concepts, particularly those related to hereditary risk for developing cancer, to aid nurses in knowing when and why to refer patients. It also provides reliable information about how and why genetic and genomic testing can both aid in treatment decisions and also guide recommendations for cancer prevention and early detection. The nurse's role in genetic testing and counseling are discussed, as are questions and answers about types of testing, including direct-to-consumer genetic testing. Following genetic testing, most genetics professionals provide detailed information about recommendations for care, including recommendations for ongoing prevention and early detection. For patients who are found to have a harmful mutation, these recommendations can be extensive and are based on the personal and family medical history, as well as the specific variant. This book provides quick overviews of many of the more common hereditary variants as well as resources for more information. This handbook provides nurses with the essentials to understand genomic and hereditary cancer risk, to assist in facilitating interprofessional care with genetics and other oncology professionals, and to provide their patients with accurate and reassuring information"--
Author : William B. Coleman
Publisher : Academic Press
ISBN 13 : 0128132582
Total Pages : 634 pages
Book Rating : 4.1/5 (281 download)
Download or read book Essential Concepts in Molecular Pathology written by William B. Coleman and published by Academic Press. This book was released on 2019-11-23 with total page 634 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology
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Publisher :
ISBN 13 :
Total Pages : 136 pages
Book Rating : 4.:/5 (679 download)
Download or read book Program and Abstracts of Papers Presented at the Twenty-third Annual Symposium on Fundamental Cancer Research written by and published by . This book was released on 1969 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt:
