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Genes Environment And Psychopathology
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Book Synopsis Genes, Environment, and Psychopathology by : Kenneth S. Kendler
Download or read book Genes, Environment, and Psychopathology written by Kenneth S. Kendler and published by Guilford Press. This book was released on 2007-11-01 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: This groundbreaking volume synthesizes the results of the Virginia Adult Twin Study of Psychiatric and Substance Use Disorders, which yielded longitudinal data on more than 9,000 individuals. The authors trace how risk for depression, anxiety, eating disorders, antisocial behavior, alcoholism, and substance abuse emerges from the interplay of a variety of genetic and environmental influences. Major questions addressed include whether risk is disorder-specific, how to distinguish between correlational and causal genetic and evironmental factors, sex differences in risk, and how risk and protective factors interact over time. The book also summarizes the conceptual underpinnings of the study and describes key methodological challenges and innovations.
Book Synopsis Gene-Environment Interactions in Developmental Psychopathology by : Kenneth A. Dodge
Download or read book Gene-Environment Interactions in Developmental Psychopathology written by Kenneth A. Dodge and published by Guilford Press. This book was released on 2011-09-01 with total page 305 pages. Available in PDF, EPUB and Kindle. Book excerpt: Bringing together foremost experts, this book reviews groundbreaking gene–environment research and explores implications for clinical practice, prevention, and public policy. Presented is cutting-edge work on the interplay of genetic factors and childhood experiences in the development of mental disorders such as depression, conduct disorder, and schizophrenia. Essential topics include what scientists currently know about "susceptibility genes"; the mechanisms by which maltreatment and other stressors interact with biological susceptibilities across development; and factors that make certain children more resilient than others. Future directions for personalizing treatment and prevention efforts, thus making them more effective, are discussed.
Book Synopsis The Behavioral Genetics of Psychopathology by : Kerry L. Jang
Download or read book The Behavioral Genetics of Psychopathology written by Kerry L. Jang and published by Routledge. This book was released on 2005-03-23 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries about the genetic underpinnings of many kinds of human experience are now continually being made. This book explores the impact of these discoveries on the ways in which the common mental disorders are best conceptualized and treated. Most people think of research in genetics as the search for genes. This is only one focus of effort, and even with the reliable identification of susceptibility genes, the clinical applications of their discovery, such as gene therapies and new drug development, are a long way off. For the present, the impact of genetic research on our understanding of mental illness is tied to our ability to estimate the effect of all genes by means of family, twin, and adoption studies. The results of these studies challenge some deeply cherished ideas and theories, and support others. Of course, the effect of genes is only half the equation. The role of experience, environment, and living conditions accounts for as much, often considerably more, of the variability in psychopathology. In this book, Kerry Jang attempts not to answer questions about what is "genetic" and what is not, but about what a knowledge of the relative influence of genes versus environment means at a psychological level of analysis--to show how it changes common assumptions about classification, etiology, diagnosis, and intervention. He first offers an overview of contemporary behavioral genetics, dispels common misconceptions, responds to the criticisms that have been leveled at this new field, and describes in basic terms how genetic and environmental effects are estimated and how susceptibility genes are pinpointed. He then points to new directions in which standard nosological systems are likely to evolve as new information about vulnerabilities and covariances emerges. Finally, he synthesizes and evaluates the consistency of the last decade's findings for the most common categories of psychopathology that have been studied by behavior geneticists: mood, personality, and anxiety disorders, substance abuse; and schizophrenia and the psychotic disorders. Clinicians and researchers alike need to understand the genetic influences on the feelings and behaviors they are seeking to change or study if they are to be effective in their work. The Behavioral Genetics of Psychopathology: A Clinical Guide empowers them with this understanding.
Book Synopsis Developmental Psychopathology and Wellness by : James J. Hudziak
Download or read book Developmental Psychopathology and Wellness written by James J. Hudziak and published by American Psychiatric Pub. This book was released on 2009-02-20 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: A major benchmark in the understanding of psychiatric illness in children and adolescents, Developmental Psychopathology and Wellness reports on progress in identifying genetic and environmental influences on emotional-behavioral disorders. A team of 22 international authorities presents work that changes the way child psychiatry and clinical psychology are conceptualized, debunking misconceptions about depression, antisocial behavior, and other conditions to enhance our understanding of the causes of child psychopathology -- and improve the ways we treat these disorders. Coverage of basic principles describes the influence of genomic medicine, as explained by trailblazers in the field who demonstrate the importance of the developmental perspective. Chapters on gene-environment interaction review the important concepts of personality and temperament, cognition, and sex -- including findings from molecular genetic investigations on adolescent cognition, temperament, and brain function. Disorder-based examples show how emotional-behavioral illness and wellness attest to the interaction of genetic and environmental factors over time, providing new insight into the study of anxious depression, ADHD, autism, and antisocial personality disorders. And in considering how we can bridge the gap between research and clinical applications, Dr. Hudziak describes his family-based gene-environment approach as a means of better understanding etiopathology and treatment. Among the other significant contributions: Thomas Achenbach focuses on the importance of culture in understanding the genetic and environmental impact on children, with insights into measuring these sources of influence. Joan Kaufman reports on her seminal work on the genetic and environmental modifiers of risk and resilience in child abuse, relating maltreatment to other forms of environmental risk, genetic mediation, and reactivity. D. I. Boomsma describes the genetic architecture of childhood worry, presenting data from an extraordinary sample of 30,000 twin pairs. Frank Verhulst draws on a 14-year study to detail the advantages of the developmental perspective in understanding antisocial behavior. Stephen Faraone offers guidelines for moving beyond statistics to document the functional significance of DNA variants associated with psychopathology. As the contributors ably demonstrate, these new approaches to the care and treatment of at-risk children are applicable to daily practice, teaching, and research. Developmental Psychopathology and Wellness shows that these psychopathologies are not a matter of nature versus nurture or genes versus environment, but rather an intertwining web of them all.
Book Synopsis Gene-Environment Transactions in Developmental Psychopathology by : Patrick H. Tolan
Download or read book Gene-Environment Transactions in Developmental Psychopathology written by Patrick H. Tolan and published by Springer. This book was released on 2017-04-29 with total page 301 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the current research in gene-environment transactions (GEX) and its potential use in developing interventions and applications tailored to individual genetic makeups. Key concepts underlying GEX studies in this area are defined, identifying fundamental challenges in devising informed research questions and conducting valid and useful experiments. Chapters analyze GEX models inspired by the present day genome-based frameworks, particularly in terms of advances in identifying and understanding complex environmental factors, using examples from common psychological conditions, such as antisocial behavior, chronic physical aggression, and chronic internalizing disorder. In addition, the book presents new and potential applications of the framework in the contexts of prevention science and intervention research. Topics featured in this book include: Epigenetics and the biology of gene x environment interactions. Gene by environment interactions and its potential use for intervention strategies in anxiety disorders. The challenges and potential for research on gene-environment interactions within autism spectrum disorder. Using genetically informed prevention trials to test gene x environment hypothese. Challenges for intervention research within the GEX framework. Gene-Environment Transactions in Developmental Psychopathology is a must-have resource for researchers/professors, clinicians, and related professionals as well as graduate students in developmental psychology, psychiatry, human genetics, and related disciplines.
Book Synopsis The Behavioral Genetics of Psychopathology by : Kerry L. Jang
Download or read book The Behavioral Genetics of Psychopathology written by Kerry L. Jang and published by Routledge. This book was released on 2005-03-23 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries about the genetic underpinnings of many kinds of human experience are now continually being made. This book explores the impact of these discoveries on the ways in which the common mental disorders are best conceptualized and treated. Most people think of research in genetics as the search for genes. This is only one focus of effort, and even with the reliable identification of susceptibility genes, the clinical applications of their discovery, such as gene therapies and new drug development, are a long way off. For the present, the impact of genetic research on our understanding of mental illness is tied to our ability to estimate the effect of all genes by means of family, twin, and adoption studies. The results of these studies challenge some deeply cherished ideas and theories, and support others. Of course, the effect of genes is only half the equation. The role of experience, environment, and living conditions accounts for as much, often considerably more, of the variability in psychopathology. In this book, Kerry Jang attempts not to answer questions about what is "genetic" and what is not, but about what a knowledge of the relative influence of genes versus environment means at a psychological level of analysis--to show how it changes common assumptions about classification, etiology, diagnosis, and intervention. He first offers an overview of contemporary behavioral genetics, dispels common misconceptions, responds to the criticisms that have been leveled at this new field, and describes in basic terms how genetic and environmental effects are estimated and how susceptibility genes are pinpointed. He then points to new directions in which standard nosological systems are likely to evolve as new information about vulnerabilities and covariances emerges. Finally, he synthesizes and evaluates the consistency of the last decade's findings for the most common categories of psychopathology that have been studied by behavior geneticists: mood, personality, and anxiety disorders, substance abuse; and schizophrenia and the psychotic disorders. Clinicians and researchers alike need to understand the genetic influences on the feelings and behaviors they are seeking to change or study if they are to be effective in their work. The Behavioral Genetics of Psychopathology: A Clinical Guide empowers them with this understanding.
Book Synopsis Nature and Nurture in Mental Disorders by : Joel Paris
Download or read book Nature and Nurture in Mental Disorders written by Joel Paris and published by American Psychiatric Pub. This book was released on 2020-10-06 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, spurred particularly by the decoding of the genome, neuroscience has advanced to become the primary basis of clinical psychiatry, even as environmental risk factors for mental disorders have been deemphasized. In this thoroughly revised, second edition of Nature and Nurture in Mental Disorders, the author argues that an overreliance on biology at the expense of environment has been detrimental to the field -- that, in fact, the "nature versus nurture" dichotomy is unnecessary. Instead, he posits a biopsychosocial model that acknowledges the role an individual's predisposing genetic factors, interacting with environmental stressors, play in the etiology of many mental disorders. The first several chapters of the book provide an overview of the theories that affect the study of genes, the environment, and their interaction, examining what the empirical evidence has revealed about each of these issues. Subsequent chapters apply the integrated model to a variety of disorders, reviewing the evidence on how genes and environment interact to shape disorders including: Depressive disorders PTSD Neurodevelopmental disorders Eating disorders Personality disorders By rejecting both biological and psychosocial reductionism in favor of an interactive model, Nature and Nurture in Mental Disorders offers practicing clinicians a path toward a more flexible, effective treatment model. And where controversy or debate still exist, an extensive reference list provided at the end of the book, updated for this edition to reflect the most current literature, encourages further study and exploration.
Book Synopsis Behavior Genetics of Psychopathology by : Soo Hyun Rhee
Download or read book Behavior Genetics of Psychopathology written by Soo Hyun Rhee and published by Springer Science & Business Media. This book was released on 2014-02-03 with total page 344 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a dynamic, interdisciplinary field, behavior genetics and its evolution are being followed closely by scientists across the psychological and medical domains. The discoveries surrounding the human genome and the advancement in molecular genetic technologies have led to studies becoming increasingly sophisticated and yielding yet more conclusive and useful results. This is certainly the case in the area of child and adult psychopathology. Behavior Genetics of Psychopathology summarizes the state of the field, examining the role of genes and environment as they affect common neurodevelopmental and psychiatric conditions. Emphasizing key research areas (comorbidities, twin studies, the integration of methods), the book assesses the current literature, offers up-to-date findings, sorts through lingering controversies, and identifies a clear future agenda for the field. Expertly-written chapters focus on issues of both general salience that shape behavior genetics of psychopathology, to specific disorders of major clinical importance, among them: ADHD: the view from quantitative genetic research. Autism spectrum disorders and their complex heterogeneity Genetic influences on anxiety and depression in childhood and adolescence. Evidence for etiologically-defined subgroups within the construct of antisocial behavior. Sleep and psychopathology: the reasons for their co-occurrence. Behavioral genetic approaches to the etiology of comorbidity. Epigenetics of psychopathology. This combination of timeliness and depth of coverage make Behavior Genetics of Psychopathology a frontline resource for behavior geneticists, psychologists, psychiatrists, and neuroscientists, and is perfectly suited to graduate students looking to join these fields.
Book Synopsis Personalized Psychiatry by : Bernhard Baune
Download or read book Personalized Psychiatry written by Bernhard Baune and published by Academic Press. This book was released on 2019-10-16 with total page 604 pages. Available in PDF, EPUB and Kindle. Book excerpt: Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Book Synopsis From Neurons to Neighborhoods by : National Research Council
Download or read book From Neurons to Neighborhoods written by National Research Council and published by National Academies Press. This book was released on 2000-11-13 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: How we raise young children is one of today's most highly personalized and sharply politicized issues, in part because each of us can claim some level of "expertise." The debate has intensified as discoveries about our development-in the womb and in the first months and years-have reached the popular media. How can we use our burgeoning knowledge to assure the well-being of all young children, for their own sake as well as for the sake of our nation? Drawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and other issues. The committee issues a series of challenges to decision makers regarding the quality of child care, issues of racial and ethnic diversity, the integration of children's cognitive and emotional development, and more. Authoritative yet accessible, From Neurons to Neighborhoods presents the evidence about "brain wiring" and how kids learn to speak, think, and regulate their behavior. It examines the effect of the climate-family, child care, community-within which the child grows.
Book Synopsis Genetics, Environment and Psychopathology by :
Download or read book Genetics, Environment and Psychopathology written by and published by . This book was released on 1974 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Nature and Nurture in Personality and Psychopathology by : Joel Paris
Download or read book Nature and Nurture in Personality and Psychopathology written by Joel Paris and published by Routledge. This book was released on 2022-02-17 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Psychiatry and clinical psychology have long been divided about the roles of nature and nurture in the pathways to psychopathology. Some clinicians offer treatment almost entirely based on neuroscience. Some psychologists offer psychotherapies almost entirely based on the impact of environmental stressors. Paris argues for a balanced middle ground between nature and nurture in human development. This book reviews and integrates research showing that the key to understanding the development of mental disorders lies in interactions between genes and environment. It explores why personality is a key determinant of how people respond to stress, functioning as a kind of psychological immune system. This model represents a shift from overly simple and reductionistic constructs, based primarily on biological risks or on psychosocial risks in development. Instead, it offers a complex and multivariate approach that encourages a broader approach to treatment. This book is essential for all mental health clinicians who are interested in understanding the roles of nature and nurture in the development of psychopathology.
Book Synopsis Psychopathology in the Genome and Neuroscience Era by : Charles F. Zorumski
Download or read book Psychopathology in the Genome and Neuroscience Era written by Charles F. Zorumski and published by American Psychiatric Pub. This book was released on 2007-05-03 with total page 256 pages. Available in PDF, EPUB and Kindle. Book excerpt: The fascinating Psychopathology in the Genome and Neuroscience Era brings together selected topics in psychiatric genetics, epidemiology and prevention, and neuroscience and education. This key reference integrates this information across the fields of genetics, epidemiology, and neuroscience to arrive at an understanding of where recent advances in genetics and neuroscience -- advances that promise to enhance our understanding of human behavior and psychopathology -- are likely to influence psychopathology research and education in the near future. How will the field of psychopathology incorporate the coming avalanche of information generated by these recent advances? The answer will influence not only how mental health professionals diagnose and treat patients but also how the next generation of professionals is trained. Chapters in this exciting compilation are based on individual talks by 20 international experts at the conceptual forefront of their respective fields given at the March 2003 American Psychopathological Association annual meeting. Organized into four main sections -- the future of psychiatric genetics, diagnosis and prevention of psychiatric disorders, neurobiology and psychiatric disorders, and the future of psychiatric education -- Psychopathology in the Genome and Neuroscience Era focuses on a broad range of topics: The importance of a conceptual shift from identifying major genes for mental disorders to gaining an understanding of the role of which genes in which contexts, both biological and environmental, confer susceptibility to or protection from mental disorders or components thereof Historical perspective of gene susceptibility to mental disorders, with the same possibilities for use and misuse of genotype data as now exist for significantly heritable traits such as intelligence, and for borderline traits such as criminal behavior and alcoholism Reconceptualization of medicine and medical diagnoses to include molecular genetic components, including the importance of cell loss and neurogenesis in mood disorders Major phenotypic problems inherent in all attempts to measure psychopathology, starting with how to achieve reliability, and how to advance from reliability to validity in future revisions of DSM and ICD classifications Brain structural abnormalities in mood disorders; physiological cell death and whether or not this natural phenomenon can be converted into a pathological process, including the importance of cell loss and neurogenesis in mood disorders The influence of scientific advances, workforce issues, and educational trends on psychiatric training Psychopathology in the Genome and Neuroscience Era is a must-read reference work for anyone -- practitioners, residents, and students alike -- interested in the future of psychiatric genetics, epidemiology, and education.
Book Synopsis The Neurobiological Basis of Suicide by : Yogesh Dwivedi
Download or read book The Neurobiological Basis of Suicide written by Yogesh Dwivedi and published by CRC Press. This book was released on 2012-06-25 with total page 485 pages. Available in PDF, EPUB and Kindle. Book excerpt: With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Book Synopsis Resilience and Vulnerability by : Suniya S. Luthar
Download or read book Resilience and Vulnerability written by Suniya S. Luthar and published by Cambridge University Press. This book was released on 2003-05-05 with total page 610 pages. Available in PDF, EPUB and Kindle. Book excerpt: Table of contents
Book Synopsis Genetics of Psychopathology by : David Rosenthal
Download or read book Genetics of Psychopathology written by David Rosenthal and published by McGraw-Hill Companies. This book was released on 1971 with total page 200 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Development of Psychopathology by : Bruce Franklin Pennington
Download or read book The Development of Psychopathology written by Bruce Franklin Pennington and published by Guilford Press. This book was released on 2005-06-20 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This highly readable volume illuminates the interplay among biological, psychological, and social-contextual processes in the development of such prevalent problems as depression, schizophrenia, ADHD, dyslexia, and autism. Leading developmental scientist Bruce F. Pennington explains the variety of methods currently being used to investigate the mind-brain connection, including behavioral and molecular genetics, studies of brain structure and function, neuropsychology, and treatment studies. Shedding new light on where mental disorders come from, how they develop, and why they are so common, the book also examines the implications for treatment and prevention. ?
