Fused Pyrimidine Based Drug Discovery

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Fused Pyrimidine-Based Drug Discovery

Author : Raj Kumar
Publisher : Elsevier
ISBN 13 : 0443186170
Total Pages : 379 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Fused Pyrimidine-Based Drug Discovery by : Raj Kumar

Download or read book Fused Pyrimidine-Based Drug Discovery written by Raj Kumar and published by Elsevier. This book was released on 2022-10-08 with total page 379 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers the chemistry and biological activities, as well as the design of novel fused-pyrimidine scaffolds. N-Heterocyclic scaffolds are found in most known drug candidates, and are of interest to medicinal and organic chemists to design, synthesize and evaluate their biological properties. A variety of fused-pyrimidine molecules have been synthesized and extracted from natural resources, and are found to exhibit various biological activities such as antifolates, anticancer agents, analgesics, antimetabolites, CNS active agents and many more. Some of these scaffolds like purines are also known to have involvement in biological processes and are part of the framework of genetic material. This book focuses on the classification, structural chemistry, and chemical and physical properties along with various approaches for their synthesis. This book is ideal for researchers in organic chemistry both in academic and industrial settings, postgraduates in chemistry and medicinal chemistry. Covers US FDA approved fused pyrimidine containing drugs and their analyses Comprises classification based upon fusion of carbocyclic/heterocyclic rings(s) with a pyrimidine ring, and features their synthetic schemes, approaches and strategies Includes new fused-pyrimidine scaffolds, allowing the researcher to predict the mechanisms involved in their synthesis Covers fused pyrimidine containing bioactive compounds from the natural sources Covers in silico studies of known fused pyrimidines and Structure-Activity Relationship (SAR), which will encourage the development of new or modified existing scaffolds with specific biological activities

Fused Pyrimidine-Based Drug Discovery

Author : Raj Kumar
Publisher : Elsevier
ISBN 13 : 0323903614
Total Pages : 320 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Fused Pyrimidine-Based Drug Discovery by : Raj Kumar

Download or read book Fused Pyrimidine-Based Drug Discovery written by Raj Kumar and published by Elsevier. This book was released on 2022-08-01 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fused Pyrimidine-Based Drug Discovery covers all categories of fused-pyrimidines along with pharmacological and in silico studies. It covers chemistry and biological activities, as well as the design of novel fused-pyrimidine scaffolds. N-Heterocyclic scaffolds are found in most known drug candidates and are of interest to medicinal and organic chemists to design, synthesize and evaluate their biological properties. A variety of fused-pyrimidine molecules have been synthesized and extracted from natural resources and are found to exhibit various biological activities such as antifolates, anticancer agents, analgesics, antimetabolites, CNS active agents, and many more. This book focuses on nomenclature, structural chemistry, and chemical and physical properties, along with various approaches for their synthesis. It is ideal for researchers in organic chemistry, both in academic and industrial settings and for postgraduates in chemistry and medicinal chemistry. Features synthetic schemes, approaches and strategies for fused pyrimidine scaffolds Includes new fused-pyrimidine scaffolds, allowing the researcher to predict the mechanisms involved in their synthesis Covers in silico studies of known fused pyrimidines and Structure Activity Relationship (SAR) that encourage the development of new or modified existing scaffolds with specific biological activities

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Author : Bimal Krishna Banik
Publisher : Elsevier
ISBN 13 : 0443161674
Total Pages : 699 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Green Approaches in Medicinal Chemistry for Sustainable Drug Design by : Bimal Krishna Banik

Download or read book Green Approaches in Medicinal Chemistry for Sustainable Drug Design written by Bimal Krishna Banik and published by Elsevier. This book was released on 2024-05-31 with total page 699 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extensive experimentation and high failure rates are a well-recognized downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry 2e reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context to the growth of green chemistry in relation to drug discovery, the book goes on to identify a broad range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global team of experts, Sustainable and Green Approaches in Medicinal Chemistry, Second Edition encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists and all those in related fields across both academia and industry in integrating these approaches into their own work. This second volume of the second edition includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug development Reveals risk factors associated with the drug development process and the ways sustainable approaches can help address these Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability

Heterogeneous Catalytic Materials

Author : Guido Busca
Publisher : Newnes
ISBN 13 : 044459521X
Total Pages : 479 pages
Book Rating : 4.4/5 (445 download)

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Book Synopsis Heterogeneous Catalytic Materials by : Guido Busca

Download or read book Heterogeneous Catalytic Materials written by Guido Busca and published by Newnes. This book was released on 2014-05-23 with total page 479 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heterogeneous Catalytic Materials discusses experimental methods and the latest developments in three areas of research: heterogeneous catalysis; surface chemistry; and the chemistry of catalysts. Catalytic materials are those solids that allow the chemical reaction to occur efficiently and cost-effectively. This book provides you with all necessary information to synthesize, characterize, and relate the properties of a catalyst to its behavior, enabling you to select the appropriate catalyst for the process and reactor system. Oxides (used both as catalysts and as supports for catalysts), mixed and complex oxides and salts, halides, sulfides, carbides, and unsupported and supported metals are all considered. The book encompasses applications in industrial chemistry, refinery, petrochemistry, biomass conversion, energy production, and environmental protection technologies. Provides a systematic and clear approach of the synthesis, solid state chemistry and surface chemistry of all solid state catalysts Covers widely used instrumental techniques for catalyst characterization, such as x-ray photoelectron spectroscopy, scanning electron microscopy, and more Includes characterization methods and lists all catalytic behavior of the solid state catalysts Discusses new developments in nanocatalysts and their advantages over conventional catalysts

Sweet Biochemistry

Author : Asha Kumari
Publisher : Elsevier
ISBN 13 : 0443153493
Total Pages : 243 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Sweet Biochemistry by : Asha Kumari

Download or read book Sweet Biochemistry written by Asha Kumari and published by Elsevier. This book was released on 2023-07-20 with total page 243 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sweet Biochemistry: Remembering Structures, Cycles, and Pathways by Mnemonics, Second Edition makes biochemistry lively, interesting and memorable by connecting objects, images and stories to biochemistry concepts. Here, Dr. Asha Kumari has converted cycles and difficult pathways into very simple formula and short stories and images to help readers see things in complicated cycles and better visualize biochemistry. As biochemistry is evolving steadily, with new and impactful topics, this new edition has been fully updated to include mnemonics on timely topics in biochemistry such as DNA replication, RNA, transcription, translation, and CRISPR technology, as well as fundamentals of immunity. Provides quick, indigenous formula, mnemonics, figures, poems and short stories to absorb key concepts in biochemistry Presents original diagrams that are easy to recall Features simplified tables for remembering distinguishing features Updated to address evolving topics in basic and medical biochemistry, including DNA replication, RNA transcription and translation and immunity fundamentals

Privileged Scaffolds in Medicinal Chemistry

Author : Stefan Bräse
Publisher : Royal Society of Chemistry
ISBN 13 : 1782620303
Total Pages : 486 pages
Book Rating : 4.7/5 (826 download)

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Book Synopsis Privileged Scaffolds in Medicinal Chemistry by : Stefan Bräse

Download or read book Privileged Scaffolds in Medicinal Chemistry written by Stefan Bräse and published by Royal Society of Chemistry. This book was released on 2015-11-20 with total page 486 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book addresses the various classes of privileged scaffolds and covers the history of their discovery and use.

Advances in Polymer Chemistry and Methods Reported in Recent US Patents

Author : Thomas F. DeRosa
Publisher : Wiley
ISBN 13 : 9780470312865
Total Pages : 0 pages
Book Rating : 4.3/5 (128 download)

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Book Synopsis Advances in Polymer Chemistry and Methods Reported in Recent US Patents by : Thomas F. DeRosa

Download or read book Advances in Polymer Chemistry and Methods Reported in Recent US Patents written by Thomas F. DeRosa and published by Wiley. This book was released on 2008-10-06 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The objective of this book is to convey to academic and industrial researchers and students advances in synthetic and characterization methods in 9 selected areas of polymer chemistry reported in 2007-2008 US Patents. It reviews the impact of newer bulk anionic, cationic, and free radical polymerization methods within selected industrial applications. Bulk and surface crosslinking agents using selected bi- and tri-functional reagents, photochemical methods, or free radical agents are also reviewed. Finally, there is a separate section on cationic and cationic ring opening polymerization reactions describing di- and tri-heterocyclic monomers and their use in medical devices.

Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin

Author : Sarbani Pal
Publisher : Elsevier
ISBN 13 : 0128154462
Total Pages : 216 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin by : Sarbani Pal

Download or read book Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin written by Sarbani Pal and published by Elsevier. This book was released on 2018-10-16 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: Isocoumarin, Thiaisocoumarin and Phosphaisocoumarin: Natural Occurrences, Synthetic Approaches and Pharmaceutical Applications gives an overview of the various aspects of this class of heterocycle, with a major focus on synthesis and biological activity. Aromatic δ lactones or isocoumarins with thiaisocoumarins, phosphaisocoumarins and a-pyranone fused with a heteroaryl ring constitute an important class of heterocyclic compounds. This book provides the methods applied for the synthesis of thiaisocoumarins, phosphaisocoumarins, and a-pyranone fused with a heteroaryl ring. It is useful to medicinal and natural product chemists who want to synthesize target molecules and develop cutting-edge technologies to provide better solutions to researchers. Features an overview of isocoumarins and their role in pharmaceutical research Presents a template for the design, discovery and development of new and potential drugs in various therapeutic areas Includes comprehensive coverage of the synthesis of isocoumarins, from traditional methods, to transition metal catalyzed methods Looks at future applications for these important compounds in the areas of drug discovery and pharmaceutical research

Comprehensive Medicinal Chemistry III

Author : Samuel Chackalamannil
Publisher :
ISBN 13 : 9780081022474
Total Pages : 674 pages
Book Rating : 4.0/5 (224 download)

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Book Synopsis Comprehensive Medicinal Chemistry III by : Samuel Chackalamannil

Download or read book Comprehensive Medicinal Chemistry III written by Samuel Chackalamannil and published by . This book was released on 2017 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Synthesis of Best-Seller Drugs

Author : Ruben Vardanyan
Publisher : Academic Press
ISBN 13 : 0124115241
Total Pages : 868 pages
Book Rating : 4.1/5 (241 download)

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Book Synopsis Synthesis of Best-Seller Drugs by : Ruben Vardanyan

Download or read book Synthesis of Best-Seller Drugs written by Ruben Vardanyan and published by Academic Press. This book was released on 2016-01-07 with total page 868 pages. Available in PDF, EPUB and Kindle. Book excerpt: Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

Author : Reed E. Pyeritz
Publisher : Academic Press
ISBN 13 : 0128152370
Total Pages : 320 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics by : Reed E. Pyeritz

Download or read book Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics written by Reed E. Pyeritz and published by Academic Press. This book was released on 2021-11-02 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Perinatal and Reproductive Genetics, Seventh Edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies in this growing field. The book is ideal for medical students, residents, physicians and researchers involved in the care of patients with genetic conditions. This comprehensive, yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine more broadly. Chapters from leading international researchers and clinicians focus on topics ranging from single gene testing to whole genome sequencing, whole exome sequencing, gene therapy, genome editing approaches, FDA regulations on genomic testing and therapeutics, and ethical aspects of employing genomic technologies. Fully revised and up-to-date, this new edition introduces genetic researchers, students and healthcare professionals to genomic technologies, testing and therapeutic applications Examines key topics and developing methods within genomic testing and therapeutics, including single gene testing, whole genome and whole exome sequencing, gene therapy and genome editing, variant Interpretation and classification, and ethical aspects of applying genomic technologies Includes color images that support the identification, concept illustration, and method of processing Features contributions by leading international researchers and practitioners of medical genetics Provides a robust companion website that offers further teaching tools and links to outside resources and articles to stay up-to-date on the latest developments in the field

Isonitrile Chemistry

Author : Ivar Ugi
Publisher : Elsevier
ISBN 13 : 0323157335
Total Pages : 293 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Isonitrile Chemistry by : Ivar Ugi

Download or read book Isonitrile Chemistry written by Ivar Ugi and published by Elsevier. This book was released on 2012-12-02 with total page 293 pages. Available in PDF, EPUB and Kindle. Book excerpt: Organic Chemistry, Volume 20: Isonitrile Chemistry discusses the fundamental aspects of the chemistry of isonitriles. This book provides an introduction to as well as a thorough coverage of isonitrile chemistry. Organized into 10 chapters, this volume begins with an overview of the general properties and structure of isonitriles. This text then examines the quantitative study of the kinetics of isonitrile rearrangement as well as the principal resonance structure of the isonitrile molecule. Other chapters consider the experimental and theoretical findings on the fall-off behavior of the unimolecular rate constants of different isonitriles with pressure. This book discusses as well the behavior of isonitriles toward a center of low electron density, which is particularly manifested in the reactivity of alkyl and aryl isonitriles toward diborane and alkyl or arylboranes. The final chapter deals with the inorganic coordination chemistry of isonitriles. This book is a valuable resource for organic chemists.

Dehydroacetic Acid and Its Derivatives

Author : Santhosh Penta
Publisher : Elsevier
ISBN 13 : 0081019270
Total Pages : 148 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Dehydroacetic Acid and Its Derivatives by : Santhosh Penta

Download or read book Dehydroacetic Acid and Its Derivatives written by Santhosh Penta and published by Elsevier. This book was released on 2017-03-31 with total page 148 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dehydroacetic acid (DHA) and its derivatives are a rich source of active compounds and have found broad applications in various fields due to their high chemical reactivity and physiological properties. Dehydroacetic Acid and Its Derivatives outlines the use of DHA and its derivatives for the synthesis of pharmacologically active heterocyclic compounds. Beginning with an introduction to the chemistry and reactivity of Dehydroacetic Acid, the book goes on to outline the key ring transformation reactions of DHA. The synthesis of various derivatives is then discussed, before a wide range of metal complexes of DHA are explored in detail. The book then concludes with a review of DHA’s biological importance and its impressive range of pharmacological activities, including anti-cancer, anti-bacterial, anti-fungal and analgesic properties. For those researching the synthesis of bioactive heterocyclic compounds, Dehydroacetic Acid and Its Derivatives is a valuable guide conveying the fundamental knowledge needed to facilitate and enhance the successful synthesis of lead molecules. Gives detailed information of the underlying chemistry of Dehydroacetic acid and its derivatives Highlights different approaches for the synthesis of derivatives, including metal complexes Explores the biological importance of Dehydroacetic Acid

Medicinal Chemistry of Anticancer Drugs

Author : Carmen Avendaño
Publisher : Elsevier
ISBN 13 : 0444626670
Total Pages : 767 pages
Book Rating : 4.4/5 (446 download)

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Book Synopsis Medicinal Chemistry of Anticancer Drugs by : Carmen Avendaño

Download or read book Medicinal Chemistry of Anticancer Drugs written by Carmen Avendaño and published by Elsevier. This book was released on 2015-06-11 with total page 767 pages. Available in PDF, EPUB and Kindle. Book excerpt: Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design. Presents information in a clear and concise way using a large number of figures Historical background provides insights on how the process of drug discovery in the anticancer field has evolved Extensive references to primary literature

Multicomponent Reactions towards Heterocycles

Author : Erik Van der Eycken
Publisher : John Wiley & Sons
ISBN 13 : 3527349081
Total Pages : 626 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Multicomponent Reactions towards Heterocycles by : Erik Van der Eycken

Download or read book Multicomponent Reactions towards Heterocycles written by Erik Van der Eycken and published by John Wiley & Sons. This book was released on 2022-03-21 with total page 626 pages. Available in PDF, EPUB and Kindle. Book excerpt: Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic chemists in academia and industry alike.

Chemistry of Biologically Potent Natural Products and Synthetic Compounds

Author : Shahid Ul-Islam
Publisher : John Wiley & Sons
ISBN 13 : 1119640342
Total Pages : 434 pages
Book Rating : 4.1/5 (196 download)

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Book Synopsis Chemistry of Biologically Potent Natural Products and Synthetic Compounds by : Shahid Ul-Islam

Download or read book Chemistry of Biologically Potent Natural Products and Synthetic Compounds written by Shahid Ul-Islam and published by John Wiley & Sons. This book was released on 2021-06-29 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: In view of their promising biological and pharmaceutical activities, natural product inspired and heterocyclic compounds have recently gained a reputation in the field of medicinal chemistry. Over the past decades, intensive research efforts have been ongoing to understand the synthesis, biochemistry and engineering involved in their preparation and action mechanisms. Several novel natural product derivatives, heterocyclic and other synthetic compounds, have been reported to have shown interesting biological activities including anticancer, antimicrobial, anti-inflammatory, anti-glycemic, anti-allergy and antiviral etc. Chemistry of Biologically Potent Natural Products and Synthetic Compounds provides up-to-date information on new developments and most recent medicinal applications of the natural products and derivatives, as well as the chemistry and synthesis of heterocyclic and other related compounds.

Modern Applications of Cycloaddition Chemistry

Author : Paolo Quadrelli
Publisher : Elsevier
ISBN 13 : 0128152745
Total Pages : 352 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Modern Applications of Cycloaddition Chemistry by : Paolo Quadrelli

Download or read book Modern Applications of Cycloaddition Chemistry written by Paolo Quadrelli and published by Elsevier. This book was released on 2019-03-20 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: Modern Applications of Cycloaddition Chemistry examines this area of organic chemistry, with special attention paid to cycloadditions in synthetic and mechanistic applications in modern organic chemistry. While many books dedicated to cycloaddition reactions deal with the synthesis of heterocycles, general applications, specific applications in natural product synthesis, and the use of a class of organic compounds, this work sheds new light on pericyclic reactions by demonstrating how these valuable tools elegantly solve synthetic and mechanistic problems. The work examines how pericyclic reactions have been extensively applied to different chemistry areas, such as chemical biology, biological processes, catalyzed cycloaddition reactions, and more. This work will be useful for organic chemists who deal with organic chemistry, medicinal chemistry, agrochemistry and material chemistry. Provides details on the synthesis of antiviral and anticancer compounds, marking the key role of unconventional catalyzed cycloaddition reactions for preparing new derivatives in a unique reaction pathway that is scalable in industrial processes Contains the most up-to-date review of the use of pericyclic reactions in drug delivery Includes the enzyme-catalyzed processes involving cycloaddition reactions for different targets, demonstrating that cycloaddition is more common in nature than expected Features new applications for cycloadditions in material chemistry and provides a general view of the most recent results in the area