Author : Tsuneo Imanaka
Publisher : Springer Nature
ISBN 13 : 9811511691
Total Pages : 284 pages
Book Rating : 4.8/5 (115 download)
Book Synopsis Peroxisomes: Biogenesis, Function, and Role in Human Disease by : Tsuneo Imanaka
Download or read book Peroxisomes: Biogenesis, Function, and Role in Human Disease written by Tsuneo Imanaka and published by Springer Nature. This book was released on 2020-01-16 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides readers with a comprehensive overview of peroxisomes and their role in human diseases. It starts by describing the history of peroxisome research and then examines in detail the current understanding of the biogenesis and function of peroxisomes. It then focuses on peroxisomal disorders and the involvement of peroxisomes in cancer and age-related diseases, discussing in detail the use of model organisms to elucidate the pathogenesis of peroxisomal disorders and the physiological importance of peroxisomal proteins. Further, the book examines diagnostic and therapeutic strategies in peroxisomal disorders as well as significant recent advances. Lastly, it addresses various topics in peroxisome research, including the isolation of peroxisomes from mammalian tissues and cells, the structural biology of peroxisomal proteins, the lipidomics of peroxisomal disorders, the value of exome sequencing, and neuropsychological testing in X-linked adrenoleukodystrophy. Given its scope, the book is a valuable resource for postgraduate students and researchers in the life sciences and clinicians in the fields of internal medicine, pediatrics, and neurology.