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Author : Ulf Eriksson
Publisher :
ISBN 13 :
Total Pages : 48 pages
Book Rating : 4.:/5 (34 download)
Download or read book Functional Studies of Intracellular Retinoid Binding Proteins written by Ulf Eriksson and published by . This book was released on 1984 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Henry Weiner
Publisher : Springer Science & Business Media
ISBN 13 : 1461558719
Total Pages : 584 pages
Book Rating : 4.4/5 (615 download)
Download or read book Enzymology and Molecular Biology of Carbonyl Metabolism 6 written by Henry Weiner and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 584 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since 1982, our ever-expanding group of investigators has been meeting in exotic parts of the world to discuss aspects of three enzyme systems. The 1996 meeting was no exception. Nearly 90 scientists from 15 countries met in the small city of Deadwood, South Dakota, for four days of stimulating talks and posters and incredible scenery. Once more this meeting reflected the changing trends in biochemical research. At the 1982 meeting most of the speakers discussed isolating new enzymes and trying to characterize them. At this meeting many speakers discussed interpretations of three-dimensional struc ture or regulatory elements of the genes controlling for the tissue-specific expression of the enzyme. Hopefully, readers will find the proceedings of the meeting to be of interest. Though they reflects the scientific information that was presented at the meeting, they do not indicate the level of personal interactions that went on during the meeting. Once again, the willingness of the participants to discuss unpublished data and to share thoughts about the future directions of their research helped make this, like our previous seven meetings, a special scientific experience for those who attended.
Author : Michel Neidhart
Publisher : Academic Press
ISBN 13 : 0127999205
Total Pages : 546 pages
Book Rating : 4.1/5 (279 download)
Download or read book DNA Methylation and Complex Human Disease written by Michel Neidhart and published by Academic Press. This book was released on 2015-08-11 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA Methylation and Complex Human Disease reviews the possibilities of methyl-group-based epigenetic biomarkers of major diseases, tailored epigenetic therapies, and the future uses of high-throughput methylome technologies. This volume includes many pertinent advances in disease-bearing research, including obesity, type II diabetes, schizophrenia, and autoimmunity. DNA methylation is also discussed as a plasma and serum test for non-invasive screening, diagnostic and prognostic tests, as compared to biopsy-driven gene expression analysis, factors which have led to the use of DNA methylation as a potential tool for determining cancer risk, and diagnosis between benign and malignant disease. Therapies are at the heart of this volume and the possibilities of DNA demethylation. In cancer, unlike genetic mutations, DNA methylation and histone modifications are reversible and thus have shown great potential in the race for effective treatments. In addition, the authors present the importance of high-throughput methylome analysis, not only in cancer, but also in non-neoplastic diseases such as rheumatoid arthritis. - Discusses breaking biomarker research in major disease families of current health concern and research interest, including obesity, type II diabetes, schizophrenia, and autoimmunity - Summarizes advances not only relevant to cancer, but also in non-neoplastic disease, currently an emerging field - Describes wholly new concepts, including the linking of metabolic pathways with epigenetics - Provides translational researchers with the knowledge of both basic research and clinic applications of DNA methylation in human diseases
Author : Salah Abdel-aleem
Publisher : Springer Science & Business Media
ISBN 13 : 1461556872
Total Pages : 192 pages
Book Rating : 4.4/5 (615 download)
Download or read book Cardiac Metabolism in Health and Disease written by Salah Abdel-aleem and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: This special issue of Molecular and Cellular Biochemistry contains original research papers as well as invited reviews focused in the field of cardiac metabolism and its regulation under normal and disease conditions. These papers cover many areas under intensive and rapid development such as the regulation of fatty acid oxidation in the heart, the role of cardiac glycogen during ischemia, the role of CPT I isoenzymes, the pathophysiology of diabetic cardiomyopathy, cardiac protection through regulation of energy production, the role of fatty acid binding protein under normal and pathological conditions, and several other important topics in this area of research. We hope that this special issue of Molecular and Cellular Biochemistry provides an up-to-date source of information for scientists and clinicians interested in the mechanism by which cardiac metabolism is regulated in health and disease and the mechanistic relationship between disturbances in cardiac metabolism and the genesis of cardiovascular diseases.
Author : Wolfgang B. Liedtke, MD, PH.D.
Publisher : CRC Press
ISBN 13 : 1420005847
Total Pages : 502 pages
Book Rating : 4.4/5 (2 download)
Download or read book TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades written by Wolfgang B. Liedtke, MD, PH.D. and published by CRC Press. This book was released on 2006-09-29 with total page 502 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st
Author :
Publisher :
ISBN 13 : 9780815332183
Total Pages : 0 pages
Book Rating : 4.3/5 (321 download)
Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Georg Hennemann
Publisher : Marcel Dekker
ISBN 13 :
Total Pages : 656 pages
Book Rating : 4.3/5 (91 download)
Download or read book Thyroid Hormone Metabolism written by Georg Hennemann and published by Marcel Dekker. This book was released on 1986 with total page 656 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : W.J. Cunliffe
Publisher : Springer Science & Business Media
ISBN 13 : 9401163499
Total Pages : 312 pages
Book Rating : 4.4/5 (11 download)
Download or read book Retinoid Therapy written by W.J. Cunliffe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt: The impact of the retinoids in clinical practice has primarily been in dermatology. When Dr Werner Bollag began his basic research and screening programme in the early 1960's, the expectation was that the retinoids would have a major impact on oncology. However, the laboratory and clinical experiences of Bollag and his colleagues in Switzerland, Stuttgen and Orfanos in Germany, led to publications on both etretinates (Tigason) and isotretinoin (Roaccutane) in the years between 1972 and 1976 in the field of dermatology. In fact the first symposium on retinoid research held in Berlin in 1981 was almost entirely dermatological. A year later a retinoid workshop in Iowa was designed to provide a forum for dermatolog ists from the USA involved in specific protocols investigating oral retinoids. In the UK, research into the retinoids began rather later than in Continental Europe or in the USA, although Tigason was first marketed here. It was felt in late 1982 that as many dermatologists had relatively little experience with these compounds it would be appropriate to hold an International Symposium on retinoid therapy in the UK. Thus on 16-18 May 1983 in London, 37 speakers from 11 countries addressed an audience of 300, aminly UK, dermatologists. The scientific organizing committee consisted of but two persons Dr William Cunliffe of Leeds General Infirmary, representing the European Society of Dermatolo gical Research, and myself from Roche Clinical Research. The Symposium was held under the auspices of the ESDR and of Roche Products Limited.
Author :
Publisher : Elsevier
ISBN 13 : 0080552110
Total Pages : 630 pages
Book Rating : 4.0/5 (85 download)
Download or read book Osmosensing and Osmosignaling written by and published by Elsevier. This book was released on 2007-10-01 with total page 630 pages. Available in PDF, EPUB and Kindle. Book excerpt: For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of osmosensing and osmosignaling written by experts in the field.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309039940
Total Pages : 765 pages
Book Rating : 4.3/5 (9 download)
Download or read book Diet and Health written by National Research Council and published by National Academies Press. This book was released on 1989-01-01 with total page 765 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diet and Health examines the many complex issues concerning diet and its role in increasing or decreasing the risk of chronic disease. It proposes dietary recommendations for reducing the risk of the major diseases and causes of death today: atherosclerotic cardiovascular diseases (including heart attack and stroke), cancer, high blood pressure, obesity, osteoporosis, diabetes mellitus, liver disease, and dental caries.
Author :
Publisher : Academic Press
ISBN 13 : 0128211520
Total Pages : 432 pages
Book Rating : 4.1/5 (282 download)
Download or read book Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Optical Imaging and Conjugation written by and published by Academic Press. This book was released on 2020-05-29 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Methods for Optical Imaging and Conjugation, Volume 639, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Fluorogenic detection of protein aggregates in live cells using the AggTag method, Synthesis and Application of Ratiometric Probes for Hydrogen Peroxide Detection, Chemical Tools for Multicolor Protein FRET with Tryptophan, Fluorescing Isofunctional Ribonucleosides for Adenosine Deaminase Activity and Inhibition, Temporal profiling establishes a dynamic S-palmitoylation cycle, Solvation-guided design of fluorescent probes for discrimination of amyloids, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the Methods in Enzymology series - Includes the latest information on retinoid signaling pathways
Author : George J. Brewer
Publisher : Academic Press
ISBN 13 : 0128093013
Total Pages : 328 pages
Book Rating : 4.1/5 (28 download)
Download or read book Essential and Toxic Trace Elements and Vitamins in Human Health written by George J. Brewer and published by Academic Press. This book was released on 2020-06-14 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt: Essential and Toxic Trace Elements and Vitamins in Human Health is a comprehensive guide to the wide variety of micronutrients that affect human health, including fat-soluble and water-soluble vitamins that support diverse biochemical functions, trace elements with established and suggested links to health maintenance, and elements with known human toxicity such as arsenic, cadmium, and lead. An essential reference text for nutritionists working in academia and functional food and supplement industries, dieticians, and clinicians, Essential and Toxic Trace Elements and Vitamins in Human Health provides an in-depth look at toxic trace elements and essential vitamins and minerals and their direct influence on the body's overall health with expert research from renowned scientists. - Presents a balanced scientific view of essential and nonessential micronutrients with an in-depth analysis of the biochemical functions each plays in human health - Examines particular micronutrients in detail with coverage of clinical aspects, interaction with other micronutrients, immunological effects, cognitive functions and epigenetics - Focuses on effective management of micronutrient deficiencies and on toxicity implications of overexposure
Author : Jacqueline M. Matthews
Publisher : Springer Science & Business Media
ISBN 13 : 1461432294
Total Pages : 184 pages
Book Rating : 4.4/5 (614 download)
Download or read book Protein Dimerization and Oligomerization in Biology written by Jacqueline M. Matthews and published by Springer Science & Business Media. This book was released on 2012-09-04 with total page 184 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.
Author : Subhrangsu S. Mandal
Publisher : John Wiley & Sons
ISBN 13 : 3527322817
Total Pages : 678 pages
Book Rating : 4.5/5 (273 download)
Download or read book Gene Regulation, Epigenetics and Hormone Signaling written by Subhrangsu S. Mandal and published by John Wiley & Sons. This book was released on 2017-10-23 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.
Author : Jan F.C. Glatz
Publisher : Springer
ISBN 13 : 9781461363538
Total Pages : 205 pages
Book Rating : 4.3/5 (635 download)
Download or read book Cellular Fatty Acid-Binding Proteins II written by Jan F.C. Glatz and published by Springer. This book was released on 2012-10-12 with total page 205 pages. Available in PDF, EPUB and Kindle. Book excerpt: Twenty years have elapsed since cytoplasmic proteins exhibiting high-affinity binding of long-chain fatty acids were first identified (Ockner et al., Science 177:56-58, 1972). These cellular fatty acid-binding proteins (FABPs) are now well established to comprise a ligand-defined group of macromolecules belonging to a family of cytoplasmic lipid binding proteins. Unique features of the FABPs are the existence of distinct types of FABP and that these are found in a variety of tissues in remarkable abundance, with some cells expressing more than one type. The physiological significance of the FABPs has only partly been elucidated. By increasing the cytoplasmic solubilization of fatty acids, the cellular FABPs are considered to function primarily in intracellular fatty acid transport, but may also be assigned important regulatory roles in cellular lipid homeostasis as well as in the modulation of cell growth and differentiation. The broad interests in cellular FABPs has led to the organization of the 1st International Workshop on Fatty Acid-Binding Protein, held in Maastricht, the Netherlands, in 1989. Prompted by the success of the first meeting, the 2nd International Workshop on Fatty-Acid-Binding Proteins, which was held again in Maastricht, on August 31 and September 1, 1992, brought together scientific scpecialists in the field of FABP research for two days of intensive and fruitful discussion. This volume is a collection of selected papers from this conference, and thus provides the state-of-the-art knowledge of cellular FABPs. The contributors to this issue represent pioneering as well as new investigators, and also reflect the multidisciplinary nature of research in this exciting and rapidly progressing field.
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309169917
Total Pages : 101 pages
Book Rating : 4.3/5 (91 download)
Download or read book Scientific Advances in Animal Nutrition written by National Research Council and published by National Academies Press. This book was released on 2002-02-07 with total page 101 pages. Available in PDF, EPUB and Kindle. Book excerpt: The science of animal nutrition has made significant advances in the past century. In looking back at the discoveries of the 20th century, we can appreciate the tremendous impact that animal nutrition has had on our lives. From the discovery of vitamins and the sweeping shift in the use of oilseeds to replace animal products as dietary protein sources for animals during the war times of the 1900s-to our integral understanding of nutrients as regulators of gene expression today-animal nutrition has been the cornerstone for scientific advances in many areas. At the milestone of their 70th year of service to the nation, the National Research Council's (NRC) Committee on Animal Nutrition (CAN) sought to gain a better understanding of the magnitude of recent discoveries and directions in animal nutrition for the new century we are embarking upon. With financial support from the NRC, the committee was able to organize and host a symposium that featured scientists from many backgrounds who were asked to share their ideas about the potential of animal nutrition to address current problems and future challenges.
Author : Malcolm G. Parker
Publisher :
ISBN 13 :
Total Pages : 434 pages
Book Rating : 4.3/5 (91 download)
Download or read book Nuclear Hormone Receptors written by Malcolm G. Parker and published by . This book was released on 1991 with total page 434 pages. Available in PDF, EPUB and Kindle. Book excerpt: An overview of the supergene family made up of those nuclear hormone receptors which recognize thyroid and steroid hormones, vitamen D and retinoic acid and which are characterized by their ability to bind both ligands and the genes which respond to them.
