Free Radicals in Biology V4

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Publisher : Elsevier
ISBN 13 : 0323153720
Total Pages : 371 pages
Book Rating : 4.3/5 (231 download)

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Book Synopsis Free Radicals in Biology V4 by : William Pryor

Download or read book Free Radicals in Biology V4 written by William Pryor and published by Elsevier. This book was released on 2012-12-02 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free Radicals in Biology, Volume IV reviews diverse topics in free radical biology and covers topics ranging from radiation biology to lipid peroxidation, radical-mediated liver pathology, and chemical carcinogenesis. Radical mechanisms in prostaglandin biochemistry are also discussed, along with the use of electron spin resonance and spin trap methods to probe mechanisms of radical reactions in biological systems. Comprised of 10 chapters, this volume begins with an overview of the mechanisms of lipid peroxidation, focusing on the chemistry of fluorescent products from in vivo lipid peroxidation; the production of pentane in the expired breath of animals exposed to oxidative threats; and the chemistry of the enzyme glutathione peroxidase. The next chapter is devoted to the kinetic aspects of lipid peroxidation and the multiple ways in which autoxidants can react. The reader is then introduced to the mechanisms of hepatoxicity by synthetic chemicals present in the environment, together with direct mechanisms of radiation damage to nucleic acids. Subsequent chapters deal with spin trapping in biological systems; the role of free radicals in arylamine carcinogenesis and their influence on the structure and reactivity of melanins; and the involvement of vitamin ? and lipid antioxidants in free-radical-initiated reactions. This book will be of value to chemists, biologists, and physicians.

Electron Paramagnetic Resonance Spectroscopy

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Publisher : Springer Nature
ISBN 13 : 3030396630
Total Pages : 433 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Electron Paramagnetic Resonance Spectroscopy by : Patrick Bertrand

Download or read book Electron Paramagnetic Resonance Spectroscopy written by Patrick Bertrand and published by Springer Nature. This book was released on 2020-02-03 with total page 433 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although originally invented and employed by physicists, electron paramagnetic resonance (EPR) spectroscopy has proven to be a very efficient technique for studying a wide range of phenomena in many fields, such as chemistry, biochemistry, geology, archaeology, medicine, biotechnology, and environmental sciences. Acknowledging that not all studies require the same level of understanding of this technique, this book thus provides a practical treatise clearly oriented toward applications, which should be useful to students and researchers of various levels and disciplines. In this book, the principles of continuous wave EPR spectroscopy are progressively, but rigorously, introduced, with emphasis on interpretation of the collected spectra. Each chapter is followed by a section highlighting important points for applications, together with exercises solved at the end of the book. A glossary defines the main terms used in the book, and particular topics, whose knowledge is not required for understanding the main text, are developed in appendices for more inquisitive readers.

Yearbook of Intensive Care and Emergency Medicine 1993

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Publisher : Springer Science & Business Media
ISBN 13 : 3642849040
Total Pages : 675 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Yearbook of Intensive Care and Emergency Medicine 1993 by : Jean-Louis Vincent

Download or read book Yearbook of Intensive Care and Emergency Medicine 1993 written by Jean-Louis Vincent and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Yearbook compiles the most recent, widespread developments of experimental and clinical research and practice in one comprehensive reference book. It is addressed to everyone involved in internal medicine, anesthesia, surgery, pediatrics, intensive care and emergency medicine.

Oxidative Stress and Antioxidant Protection

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Publisher : John Wiley & Sons
ISBN 13 : 111883240X
Total Pages : 742 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Oxidative Stress and Antioxidant Protection by : Donald Armstrong

Download or read book Oxidative Stress and Antioxidant Protection written by Donald Armstrong and published by John Wiley & Sons. This book was released on 2016-01-14 with total page 742 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oxidative Stress and Antioxidant Protection: The Science of Free Radical Biology and Disease Oxidative Stress and Antioxidant Protection begins with a historical perspective of pioneers in oxidative stress with an introductory section that explains the basic principles related to oxidative stress in biochemistry and molecular biology, demonstrating both pathways and biomarkers. This section also covers diagnostic imaging and differential diagnostics. The following section covers psychological, physiologic, pharmacologic and pathologic correlates. This section addresses inheritance, gender, nutrition, obesity, family history, behavior modification, natural herbal-botanical products, and supplementation in the treatment of disease. Clinical trials are also summarized for major medical disorders and efficacy of treatment, with particular focus on inflammation, immune response, recycling, disease progression, outcomes and interventions. Each of the chapters describes what biomarker(s) and physiological functions may be relevant to a concept of specific disease and potential alternative therapy. The chapters cover medical terminology, developmental change, effects of aging, senescence, lifespan, and wound healing, and also illustrates cross-over exposure to other fields. The final chapter covers how and when to interpret appropriate data used in entry level biostatistics and epidemiology. Authored and edited by leaders in the field, Oxidative Stress and Antioxidant Protection will be an invaluable resource for students and researchers studying cell biology, molecular biology, and biochemistry, as well professionals in various health science fields.

Smart Nanodevices for Point-of-Care Applications

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Publisher : CRC Press
ISBN 13 : 1000593843
Total Pages : 360 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Smart Nanodevices for Point-of-Care Applications by : Suvardhan Kanchi

Download or read book Smart Nanodevices for Point-of-Care Applications written by Suvardhan Kanchi and published by CRC Press. This book was released on 2022-06-23 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Smart Nanodevices for Point-of-Care Applications examines the latest trends on the capabilities of nanomaterials for point-of-care (PoC) diagnostics and explains how these materials can help to strengthen, miniaturize, and improve the quality of diagnostic devices. A thorough explanation of all-in-one nanosmart devices is included, incorporating all of the applications and fundamentals of these smart devices. This book provides practical information on the following: novel and effective smart materials, better-quality health management, effective management of a disease, potential point-of-care devices, and mobile nanosensors. Additional Features Includes in-depth research based collation of the latest trends of smart devices Provides practical information on all-in-one nanosmart devices Explains how nanomaterials can help to strengthen and improve the quality of diagnostic devices Emphasizes the development of smart nanodevices, especially the miniaturization aspect

Gerontology and Geriatrics for NPs and PAs - E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323608469
Total Pages : 719 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Gerontology and Geriatrics for NPs and PAs - E-Book by : Jill R. Beavers-Kirby

Download or read book Gerontology and Geriatrics for NPs and PAs - E-Book written by Jill R. Beavers-Kirby and published by Elsevier Health Sciences. This book was released on 2023-03-23 with total page 719 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by NPs and PAs who have a wealth of experience in the care of older adults across all practice settings, Gerontology and Geriatrics for NPs and PAs takes an evidence-based approach to both gerontology and geriatrics, incorporating the latest national and international guidelines and standards of care. This first-of-its-kind text takes an interprofessional, teamwork-based approach that reflects Interprofessional Education Collaborative (IPEC) core competencies, as well as the unique perspectives that NPs and PAs each bring to the collaborative care of older adults. - Covers both primary care and acute care of older adults and fully addresses both graduate-level and practitioner core competencies necessary for optimal care of older adults. - Places a strong emphasis on wellness (including nutrition and the Healthy People 2020 targets), normal aging, common syndromes of aging, disease management, patient safety (particularly in acute care settings), and a patient-centered care approach. - Features vibrant, full-color illustrations, a full-color design for ease of navigation, and graduate-level learning features that include Key Points at the end of each chapter for quick reference and exam preparation. - Addresses a wide range of topics specifically focused on the common medical problems of older adults, with chapters logically organized for efficient study and quick clinical reference. Evolve Instructor site with an image collection and test bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.

Redox Signaling and Regulation in Biology and Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 3527627596
Total Pages : 514 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Redox Signaling and Regulation in Biology and Medicine by : Claus Jacob

Download or read book Redox Signaling and Regulation in Biology and Medicine written by Claus Jacob and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first entry-level guide to the multifaceted field takes readers one step further than existing textbooks. In an easily accessible manner, the authors integrate the biochemistry, cell biology and medical implications of intracellular redox processes, demonstrating that complex science can be presented in a clear and almost entertaining way. Perfect for students and junior researchers, this is an equally valuable addition to courses in biochemistry, molecular biology, cell biology, and human physiology.

Antioxidants in Systems of Varying Complexity

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Publisher : CRC Press
ISBN 13 : 1000517578
Total Pages : 371 pages
Book Rating : 4.0/5 (5 download)

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Book Synopsis Antioxidants in Systems of Varying Complexity by : Lyudmila N. Shishkina

Download or read book Antioxidants in Systems of Varying Complexity written by Lyudmila N. Shishkina and published by CRC Press. This book was released on 2019-09-02 with total page 371 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume brings together innovative research, new concepts, and novel developments in the study of chemistry and biological activity of antioxidants. It is a collection of chapters on new scientific research and practical applications from chemists at several prestigious scientific institutions. It looks at recent significant research and reports on new methodologies and important applications in the field of chemical kinetics.

Oxidative Stress in Aquatic Ecosystems

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Publisher : John Wiley & Sons
ISBN 13 : 1444345966
Total Pages : 818 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Oxidative Stress in Aquatic Ecosystems by : Doris Abele

Download or read book Oxidative Stress in Aquatic Ecosystems written by Doris Abele and published by John Wiley & Sons. This book was released on 2011-11-03 with total page 818 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reactive oxygen species (ROS) are increasingly appreciated as down-stream effectors of cellular damage and dysfunction under natural and anthropogenic stress scenarios in aquatic systems. This comprehensive volume describes oxidative stress phenomena in different climatic zones and groups of organisms, taking into account specific habitat conditions and how they affect susceptibility to ROS damage. A comprehensive and detailed methods section is included which supplies complete protocols for analyzing ROS production, oxidative damage, and antioxidant systems. Methods are also evaluated with respect to applicability and constraints for different types of research. The authors are all internationally recognized experts in particular fields of oxidative stress research. This comprehensive reference volume is essential for students, researchers, and technicians in the field of ROS research, and also contains information useful for veterinarians, environmental health professionals, and decision makers.

Protein Carbonylation

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Publisher : John Wiley & Sons
ISBN 13 : 1119374952
Total Pages : 493 pages
Book Rating : 4.1/5 (193 download)

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Book Synopsis Protein Carbonylation by : Joaquim Ros

Download or read book Protein Carbonylation written by Joaquim Ros and published by John Wiley & Sons. This book was released on 2017-05-15 with total page 493 pages. Available in PDF, EPUB and Kindle. Book excerpt: Protein carbonylation has attracted the interest of a great number of laboratories since the pioneering studies at the Earl Stadtman’s lab at NIH started in early 1980s. Since then, detecting protein carbonyls in oxidative stress situations became a highly efficient tool to uncover biomarkers of oxidative damage in normal and altered cell physiology. In this book, research groups from several areas of interest have contributed to update the knowledge regarding detection, analyses and identification of carbonylated proteins and the sites where these modifications occur. The scientific community will benefit from these reviews since they deal with specific, detailed technical approaches to study formation and detection of protein carbonyls. Moreover, the biological impact of such modifications in metabolic, physiologic and structural functions and, how these alterations can help understanding the downstream effects on cell function are discussed. Oxidative stress occurs in all living organisms and affects proteins and other macromolecules: Protein carbonylation is a measure of oxidative stress in biological systems Mass spectrometry, fluorescent labelling, antibody based detection, biotinylated protein selection and other methods for detecting protein carbonyls and modification sites in proteins are described Aging, neurodegenerative diseases, obstructive pulmonary diseases, malaria, cigarette smoke, adipose tissue and its relationship with protein carbonylation Direct oxidation, glycoxidation and modifications by lipid peroxidation products as protein carbonylation pathways Emerging methods for characterizing carbonylated protein networks and affected metabolic pathways

Cholesterol

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Publisher : Academic Press
ISBN 13 : 0323858589
Total Pages : 1060 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Cholesterol by : Anna N. Bukiya

Download or read book Cholesterol written by Anna N. Bukiya and published by Academic Press. This book was released on 2022-04-26 with total page 1060 pages. Available in PDF, EPUB and Kindle. Book excerpt: With Cholesterol, Drs. Anna Bukiya and Alex Dopico have compiled a comprehensive resource on biological and clinical aspects of cholesterol, spanning biophysics and biochemistry, as well as the latest pharmacological discoveries employed to tackle disorders associated with abnormal cholesterol levels. Early chapters on basic biology offer guidance in cholesterol lab chemistry, cholesterol metabolism and synthesis, molecular evolution of cholesterol and sterols, cholesterol peptides, and cholesterol modulation. Chapters on cellular and organismal development discuss cholesterol transport in blood, lipoproteins, and cholesterol metabolism; cholesterol detection in the blood; cellular cholesterol levels; hypercholesterolemia; and the role of cholesterol in early human development. Pathophysical specialists consider familial hypobetalipoproteinemia, critical illness and cholesterol levels, coronary artery disease, CESD, cholesterol and viral pathology, cholesterol and neurodegenerative disorders, and cholesterol and substance use disorders. A final section examines pharmacology of drug delivery systems targeting cholesterol related disorders, cholesterol receptors, cholesterol reduction, statins, citrate lyase, cyclodextrins, and clinical management. Cholesterol: From Biophysics and Biochemistry to Pathology and Pharmacology empowers researchers, students, and clinicians across various disciplines to advance new cholesterol-based studies, improve clinical management, and drive drug discovery. - Ties basic biology to clinical application and drug discovery - Provides methods and protocols for lab-based cholesterol research and clinical testing - Examines the latest pharmacological discoveries employed to tackle cholesterol related disorders - Includes chapter contributions from a wide range of specialists, uniting various disciplines

Identification Of Novel Biomarkers In Ovarian Cancer: Systems Biology Approaches

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Publisher : Akademisyen Kitabevi
ISBN 13 : 6052588314
Total Pages : 39 pages
Book Rating : 4.0/5 (525 download)

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Book Synopsis Identification Of Novel Biomarkers In Ovarian Cancer: Systems Biology Approaches by : Esra GÖV

Download or read book Identification Of Novel Biomarkers In Ovarian Cancer: Systems Biology Approaches written by Esra GÖV and published by Akademisyen Kitabevi. This book was released on 2020-02-20 with total page 39 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Research Grants Index

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Publisher :
ISBN 13 :
Total Pages : 1258 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Research Grants Index by : National Institutes of Health (U.S.). Division of Research Grants

Download or read book Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants and published by . This book was released on 1968 with total page 1258 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Metalloproteins and Motor Proteins

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Publisher : Elsevier
ISBN 13 : 0443193452
Total Pages : 678 pages
Book Rating : 4.4/5 (431 download)

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Book Synopsis Metalloproteins and Motor Proteins by :

Download or read book Metalloproteins and Motor Proteins written by and published by Elsevier. This book was released on 2024-07-05 with total page 678 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metalloproteins and Motor Proteins, Volume 141 focuses on recent advances in studying metalloproteins and motor proteins, along with their roles in different pathologies and drug-resistance. Chapters include Transcriptomic Analysis Reveals Zinc-Mediated Virulence and Pathogenicity in Multidrug-Resistant Acinetobacter baumannii, The Mechanistic Insights into Different Aspects of Promiscuity in Metalloenzymes, Role of Metal ion in ion channel Mechanisms, A model of microtubule depolymerization by kinesin-8 motor proteins, Metalloproteins and metalloproteomics in health and disease, Decoding Genetic and Pathophysiological Mechanisms in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis: A Comparative Study of Differentially Expressed Genes and Implicated Pathways in Motor Neuron Disorders, and much more.Additional chapters cover Exploring the effect of disease causing mutations in metal binding sites of human ARSA in Metachromatic Leukodystrophy, Role of transmembrane proteins in regulating metalloproteins and motor proteins in human cancer, Role of transmembrane proteins in metalloproteins and motor proteinsin human neurogenesis, Role of transmembrane proteins in metalloproteins and motor proteins in human aging, Vesicle transport of metalloproteinases, Motor proteins and spermatogenesis, and much more. - Integrates experimental and computational methods for studying structure and function of metalloproteins and motor proteins and their implication in drug design - Presents timely chapters written by well-renowned authorities in their field - Contains a high number of high quality illustrations, figures, and tables and targets a very wide audience of specialists, researchers, and students

Handbook of the Biology of Aging

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Publisher : Academic Press
ISBN 13 : 0120883872
Total Pages : 682 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Handbook of the Biology of Aging by : Edward J. Masoro

Download or read book Handbook of the Biology of Aging written by Edward J. Masoro and published by Academic Press. This book was released on 2006 with total page 682 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is a collection of 21 papers comprising conceptual and technical issues, non-mammalian models and mammalian models and including issues such as aging of the female reproductive system and computer modelling in the study of aging.

Peroxiporins

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Publisher : CRC Press
ISBN 13 : 1000927784
Total Pages : 245 pages
Book Rating : 4.0/5 (9 download)

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Book Synopsis Peroxiporins by : Iria Medraño-Fernandez

Download or read book Peroxiporins written by Iria Medraño-Fernandez and published by CRC Press. This book was released on 2023-10-11 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: To produce energy, aerobic organisms transform oxygen molecules into water. This reductive mechanism yields toxic radical intermediates, collectively known as reactive oxygen species (ROS). Paradoxically, these physiological processes entail the production of potentially damaging species. Evolution has turned this apparent disadvantage into an opportunity for transmitting information. As a result, redox signaling within the cell is an efficient exquisitely organized process. A key element for its regulation is the physical separation of sources and targets into different cell compartments. Peroxiporins, H2O2 transporting proteins spanning biological membranes, distribute the signal from emitters to receptors. Thus, these channels are strategically situated in the thin line between life and death, guaranteeing adequate but safe signaling. Key Features: - Provides a brief history of the discovery and characterization of peroxiporins - Reviews key findings on hydrogen peroxide transport across biological membranes - Discusses the cartography of redox signaling in crowded cells - Includes lavish illustrations and comprehensive images to facilitate teaching - Highlights recent findings, outstanding controversies and open questions

Nutraceuticals for Aging and Anti-Aging

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Publisher : CRC Press
ISBN 13 : 100047593X
Total Pages : 751 pages
Book Rating : 4.0/5 (4 download)

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Book Synopsis Nutraceuticals for Aging and Anti-Aging by : Jayant Nemchand Lokhande

Download or read book Nutraceuticals for Aging and Anti-Aging written by Jayant Nemchand Lokhande and published by CRC Press. This book was released on 2021-11-25 with total page 751 pages. Available in PDF, EPUB and Kindle. Book excerpt: Aging can be perceived differently during different times in one’s life. Aging as a process not only influences medical and economic dimensions at an individual level but also at societal and national levels. Aging is a natural process; however, its standard definition in a healthcare context is yet unclear. To delay the aging process and to maintain quality of life until the end of life are two goals of prime importance. Various healthcare approaches are being developed and experimented on to best manage aging as if it is a disease. Nutraceuticals are value-added dietary supplement products and have an immense potential in altering key structures and functions of aging. Nutraceuticals can be a keystone in altering sub-normal performing physiological and metabolic systems due to aging. Nutraceuticals for Aging and Anti-Aging: Basic Understanding and Clinical Evidence addresses aging and anti-aging nutraceuticals based on 10 major challenges, such as cognitive health, malnutrition, substance abuse, bladder control, and oral health, among others. It examines how these challenges can be complemented with nutraceuticals and connects the applications with the traditional wisdom of the aging process. Key Features Examines the aging process, then recommends nutraceuticals for aging and anti-aging processes Describes the aging process from the western perspective, and Ayurvedic medicine (Indian traditional system) and traditional Chinese medicine perspectives Provides, whenever possible, the clinical evidence of the applications of nutraceuticals for aging and anti-aging This book is a valuable resource for physicians, clinical experts, pharmaceutical companies and their experts, nutrition specialists, entrepreneurs, chemists, pharmacists, food chemists-technologists, as well as researchers and post-graduate students involved in these specialties. Also available in the Nutraceuticals: Basic Research/Clinical Applications Series: Bioactive Peptides: Production, Bioavailability, Health Potential, and Regulatory Issues, edited by John O. Onuh, M. Selvamuthukumaran, and Yashwant V. Pathak (ISBN: 978-0-3675-1177-7) Nutraceuticals for Prenatal, Maternal and Offspring’s Nutritional Health, edited by Priyanka Bhatt, Maryam Sadat Miraghajani, Sarvadaman Pathak, and Yashwant V. Pathak (ISBN 978-1-1383-4582-9) Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applications, edited by Sheeba Varghese Gupta, and Yashwant V. Pathak (ISBN 978-1-1385-9391-6)