Forensic Dna Trace Evidence Interpretation

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Forensic DNA Trace Evidence Interpretation

Author : Duncan Taylor
Publisher : CRC Press
ISBN 13 : 1000801411
Total Pages : 565 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Forensic DNA Trace Evidence Interpretation by : Duncan Taylor

Download or read book Forensic DNA Trace Evidence Interpretation written by Duncan Taylor and published by CRC Press. This book was released on 2023-05-30 with total page 565 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA Trace Evidence Interpretation: Activity Level Propositions and Likelihood Ratios provides all foundational information required for a reader to understand the practice of evaluating forensic biology evidence given activity level propositions and to implement the practice into active casework within a forensic institution. The book begins by explaining basic concepts and foundational theory, pulling together research and studies that have accumulated in forensic journal literature over the last 20 years. The book explains the laws of probability - showing how they can be used to derive, from first principles, the likelihood ratio - used throughout the book to express the strength of evidence for any evaluation. Concepts such as the hierarchy of propositions, the difference between experts working in an investigative or evaluative mode and the practice of case assessment and interpretation are explained to provide the reader with a broad grounding in the topics that are important to understanding evaluation of evidence. Activity level evaluations are discussed in relation to biological material transferred from one object to another, the ability for biological material to persist on an item for a period of time or through an event, the ability to recover the biological material from the object when sampled for forensic testing and the expectations of the prevalence of biological material on objects in our environment. These concepts of transfer, persistence, prevalence and recovery are discussed in detail in addition to the factors that affect each of them. The authors go on to explain the evaluation process: how to structure case information and formulate propositions. This includes how a likelihood ratio formula can be derived to evaluate the forensic findings, introducing Bayesian networks and explaining what they represent and how they can be used in evaluations and showing how evaluation can be tested for robustness. Using these tools, the authors also demonstrate the ways that the methods used in activity level evaluations are applied to questions about body fluids. There are also chapters dedicated to reporting of results and implementation of activity level evaluation in a working forensic laboratory. Throughout the book, four cases are used as examples to demonstrate how to relate the theory to practice and detail how laboratories can integrate and implement activity level evaluation into their active casework.

Forensic DNA Evidence Interpretation

Author : John S. Buckleton
Publisher : CRC Press
ISBN 13 : 1315362430
Total Pages : 509 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Forensic DNA Evidence Interpretation by : John S. Buckleton

Download or read book Forensic DNA Evidence Interpretation written by John S. Buckleton and published by CRC Press. This book was released on 2018-09-03 with total page 509 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its second edition, Forensic DNA Evidence Interpretation is the most comprehensive resource for DNA casework available today. Written by leaders in the fields of biology and statistics, including a contribution from Peter Gill, the father of DNA analysis, the book emphasizes the interpretation of test results and provides the necessary formulae in an easily accessible manner. This latest edition is fully updated and includes current and emerging techniques in this fast-moving field. The book begins by reviewing all pertinent biology, and then provides information on every aspect of DNA analysis. This includes modern interpretation methods and contemporary population genetic models available for estimating DNA frequencies or likelihood ratios. Following a chapter on procedures for validating databases, the text presents overviews and performance assessments of both modern sampling uncertainty methods and current paternity testing techniques, including new guidelines on paternity testing in alignment with the International Society for Forensic Genetics. Later chapters discuss the latest methods for mixture analysis, LCN (ultra trace) analysis and non-autosomal (mito, X, and Y) DNA analysis. The text concludes with an overview of procedures for disaster victim identification and information on DNA intelligence databases. Highlights of the second edition include: New information about PCR processes, heterozygote balance and back and forward stuttering New information on the interpretation of low template DNA, drop models and continuous models Additional coverage of lineage marker subpopulation effects, mixtures and combinations with autosomal markers This authoritative book provides a link among the biological, forensic, and interpretative domains of the DNA profiling field. It continues to serve as an invaluable resource that allows forensic scientists, technicians, molecular biologists and attorneys to use forensic DNA evidence to its greatest potential.

Interpreting Complex Forensic DNA Evidence

Author : Jane Moira Taupin
Publisher : CRC Press
ISBN 13 : 1351023764
Total Pages : 117 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Interpreting Complex Forensic DNA Evidence by : Jane Moira Taupin

Download or read book Interpreting Complex Forensic DNA Evidence written by Jane Moira Taupin and published by CRC Press. This book was released on 2019-11-14 with total page 117 pages. Available in PDF, EPUB and Kindle. Book excerpt: Interpreting Complex Forensic DNA Evidence is a handy guide to recent advances—and emerging issues—in interpreting complex DNA evidence and profiles for use in criminal investigations. In certain cases, DNA cannot be connected to a specific biological material such as blood, semen or saliva. How or when the DNA was deposited may be an issue. The possibility of generating DNA profiles from touched objects, where there may not be a visible deposit, has expanded the scope and number of exhibits submitted for DNA analysis. With such advances, and increasing improvements in technological capabilities in testing samples, this means it is possible to detect ever smaller amounts of DNA. There are also many efforts underway to seek was to interpret DNA profiles that are sub-optimal—either relative to the amount required by the testing kit and, potentially, the quality of the obtained sample. Laboratories often use enhancements in order to obtain a readable DNA profile. The broad-reaching implications of improving DNA sensitivity have led to this next, emerging generation of more complex profiles. Examples partial profiles that do not faithfully reflect the proposed donor, or mixtures of partial DNA from multiple people. A complexity threshold has been proposed to limit interpretation of poor-quality data. Research is now addressing the interpretation of transfer of trace amounts of DNA. Complex issues are arising in trial that need to be reconciled as such complexity has added challenges to the interpretation of evidence and its introduction or dismissal in certain cases in the courts. Key Features: Addresses DNA transfer, from person-to-person as well as to objects Outlines each stage required to produce a DNA profile from an exhibit—including collection, handling, storage, and analysis Discusses ethics, subjectivity, and bias—including cognitive dissonance—as they relate specifically to complex DNA evidence Highlights current techniques and the latest advances in DNA analysis, including advances in familial DNA searches Interpreting Complex Forensic DNA Evidence provides tools to assist the criminal investigator, forensic expert, and legal professional when posed with a DNA result in a forensic report or testimony. The result—and any associated statistic—may not reveal any ambiguity, complexity, or the assumptions involved in deriving it. Questions from resolved criminal cases are posed, and the relevant forensic literature, provided for the reader to assess a DNA result and any associated statistic. Case studies throughout illustrate concepts and emphasize the need for conclusions in the forensic report that are supported by the data.

Forensic DNA Trace Evidence Interpretation

Author : Duncan Taylor
Publisher : CRC Press
ISBN 13 : 1000801381
Total Pages : 583 pages
Book Rating : 4.0/5 (8 download)

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Book Synopsis Forensic DNA Trace Evidence Interpretation by : Duncan Taylor

Download or read book Forensic DNA Trace Evidence Interpretation written by Duncan Taylor and published by CRC Press. This book was released on 2023-05-30 with total page 583 pages. Available in PDF, EPUB and Kindle. Book excerpt: Forensic DNA Trace Evidence Interpretation: Activity Level Propositions and Likelihood Ratios provides all foundational information required for a reader to understand the practice of evaluating forensic biology evidence given activity level propositions and to implement the practice into active casework within a forensic institution. The book begins by explaining basic concepts and foundational theory, pulling together research and studies that have accumulated in forensic journal literature over the last 20 years. The book explains the laws of probability - showing how they can be used to derive, from first principles, the likelihood ratio - used throughout the book to express the strength of evidence for any evaluation. Concepts such as the hierarchy of propositions, the difference between experts working in an investigative or evaluative mode and the practice of case assessment and interpretation are explained to provide the reader with a broad grounding in the topics that are important to understanding evaluation of evidence. Activity level evaluations are discussed in relation to biological material transferred from one object to another, the ability for biological material to persist on an item for a period of time or through an event, the ability to recover the biological material from the object when sampled for forensic testing and the expectations of the prevalence of biological material on objects in our environment. These concepts of transfer, persistence, prevalence and recovery are discussed in detail in addition to the factors that affect each of them. The authors go on to explain the evaluation process: how to structure case information and formulate propositions. This includes how a likelihood ratio formula can be derived to evaluate the forensic findings, introducing Bayesian networks and explaining what they represent and how they can be used in evaluations and showing how evaluation can be tested for robustness. Using these tools, the authors also demonstrate the ways that the methods used in activity level evaluations are applied to questions about body fluids. There are also chapters dedicated to reporting of results and implementation of activity level evaluation in a working forensic laboratory. Throughout the book, four cases are used as examples to demonstrate how to relate the theory to practice and detail how laboratories can integrate and implement activity level evaluation into their active casework.

Forensic Biology

Author : Richard Li
Publisher : CRC Press
ISBN 13 : 1420043447
Total Pages : 435 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Forensic Biology by : Richard Li

Download or read book Forensic Biology written by Richard Li and published by CRC Press. This book was released on 2008-04-24 with total page 435 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed as an accessible introduction to basic scientific principles and their application in professional practice, Forensic Biology provides a concise overview of the field. Focusing solely on the science behind the forensic analysis of biological evidence, this book highlights the principles, methods, and techniques used in forensic sero

Using Forensic DNA Evidence at Trial

Author : Jane Moira Taupin
Publisher : CRC Press
ISBN 13 : 1315360683
Total Pages : 238 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Using Forensic DNA Evidence at Trial by : Jane Moira Taupin

Download or read book Using Forensic DNA Evidence at Trial written by Jane Moira Taupin and published by CRC Press. This book was released on 2018-09-03 with total page 238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using Forensic DNA Evidence at Trial: A Case Study Approach covers the most common DNA analysis methods used in criminal trials today, including STR techniques, mitochondrial DNA, and Y-STRs. It presents some novel techniques—including familial testing and analyzing domestic animal hair—that have been recently introduced in unique cases, each of which is outlined in detail. It also illustrates special issues related to forensic DNA evidence by using court proceedings such as trials and appeals, commissions of inquiry, and government and laboratory reviews. With forensic DNA analysis becoming increasingly important at trial, the lively and sometimes bizarre cases presented in this book have been carefully chosen to highlight specific concepts, methods, and interpretations used in DNA analysis. Sections throughout examine the nature of expertise with a special focus on the role of subjectivity in the interpretation of forensic DNA evidence, emphasizing cognitive bias and extraneous context. Using both convictions and exonerations as examples, the book also discusses the strengths and limitations of DNA evidence and testing. The book is written in an accessible manner for the non-scientific reader, such that criminal lawyers, judges, and forensic experts will all understand the nature of analysis and application of DNA evidence in a variety of court cases. Extensive references—including notable trial proceedings, cross references of cases, and specific forensic statistics—round out the book and help to provide a complete understanding of forensic DNA analysis and its current usage in the courtroom.

Mute Witnesses

Author : Max M. Houck
Publisher : Academic Press
ISBN 13 : 9780123567604
Total Pages : 232 pages
Book Rating : 4.5/5 (676 download)

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Book Synopsis Mute Witnesses by : Max M. Houck

Download or read book Mute Witnesses written by Max M. Houck and published by Academic Press. This book was released on 2001 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using case studies, some of a high-profile nature, the contributors to this expert guide show how trace evidence, when handled correctly, can change the course of a criminal investigation and often affect the final outcome.

An Introduction to Forensic DNA Analysis, Second Edition

Author : Norah Rudin
Publisher : CRC Press
ISBN 13 : 9781420058505
Total Pages : 332 pages
Book Rating : 4.0/5 (585 download)

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Book Synopsis An Introduction to Forensic DNA Analysis, Second Edition by : Norah Rudin

Download or read book An Introduction to Forensic DNA Analysis, Second Edition written by Norah Rudin and published by CRC Press. This book was released on 2001-12-21 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Significant advances in DNA analysis techniques have surfaced since the 1997 publication of the bestselling An Introduction to Forensic DNA Analysis. DNA typing has become increasingly automated and miniaturized. Also, with the advent of Short Tandem Repeat (STR) technology, even the most minute sample of degraded DNA can yield a profile, providing valuable case information. However, just as the judicial system slowly and reluctantly accepted RFLP and AmpliType® PM+DQA1 typing, it is now scrutinizing the admissibility of STRs. Acknowledging STR typing as the current system of choice, An Introduction to Forensic DNA Analysis, Second Edition translates new and established concepts into plain English so that laypeople can gain insight into how DNA analysis works, from sample collection to interpretation of results. In response to the shift toward more efficient techniques, the authors cover the legal admissibility of STR typing, expand the chapter on DNA databases, and revise the section on automated analysis. They also present key decisions and appellate or supreme court rulings that provide precedent at the state and federal levels. Discussing forensic DNA issues from both a scientific and a legal perspective, the authors of An Introduction to Forensic DNA Analysis, Second Edition present the material in a manner understandable by professionals in the legal system, law enforcement, and forensic science. They cover general principles in a clear fashion and include a glossary of terms and other useful appendices for easy reference.

Introduction to Forensic DNA Evidence for Criminal Justice Professionals

Author : Jane Moira Taupin
Publisher : CRC Press
ISBN 13 : 143989910X
Total Pages : 192 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Introduction to Forensic DNA Evidence for Criminal Justice Professionals by : Jane Moira Taupin

Download or read book Introduction to Forensic DNA Evidence for Criminal Justice Professionals written by Jane Moira Taupin and published by CRC Press. This book was released on 2017-07-27 with total page 192 pages. Available in PDF, EPUB and Kindle. Book excerpt: The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting, yet for those with limited scientific knowledge, understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed for nonsc

The Evaluation of Forensic DNA Evidence

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 9780309053952
Total Pages : 274 pages
Book Rating : 4.0/5 (539 download)

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Book Synopsis The Evaluation of Forensic DNA Evidence by : National Research Council

Download or read book The Evaluation of Forensic DNA Evidence written by National Research Council and published by National Academies Press. This book was released on 1996-12-12 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

A Guide to Forensic DNA Profiling

Author : Scott Bader
Publisher : John Wiley & Sons
ISBN 13 : 1118751515
Total Pages : 951 pages
Book Rating : 4.1/5 (187 download)

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Book Synopsis A Guide to Forensic DNA Profiling by : Scott Bader

Download or read book A Guide to Forensic DNA Profiling written by Scott Bader and published by John Wiley & Sons. This book was released on 2016-03-08 with total page 951 pages. Available in PDF, EPUB and Kindle. Book excerpt: The increasingly arcane world of DNA profiling demands that those needing to understand at least some of it must find a source of reliable and understandable information. Combining material from the successful Wiley Encyclopedia of Forensic Science with newly commissioned and updated material, the Editors have used their own extensive experience in criminal casework across the world to compile an informative guide that will provide knowledge and thought-provoking articles of interest to anyone involved or interested in the use of DNA in the forensic context. Following extensive introductory chapters covering forensic DNA profiling and forensic genetics, this comprehensive volume presents a substantial breadth of material covering: Fundamental material – including sources of DNA, validation, and accreditation Analysis and interpretation – including, extraction, quantification, amplification and interpretation of electropherograms (epgs) Evaluation – including mixtures, low template, and transfer Applications – databases, paternity and kinship, mitochondrial-DNA, wildlife DNA, single-nucleotide polymorphism, phenotyping and familial searching Court - report writing, discovery, cross examination, and current controversies With contributions from leading experts across the whole gamut of forensic science, this volume is intended to be authoritative but not authoritarian, informative but comprehensible, and comprehensive but concise. It will prove to be a valuable addition, and useful resource, for scientists, lawyers, teachers, criminologists, and judges.

Handbook of Trace Evidence Analysis

Author : Vincent J. Desiderio
Publisher : John Wiley & Sons
ISBN 13 : 1118962095
Total Pages : 480 pages
Book Rating : 4.1/5 (189 download)

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Book Synopsis Handbook of Trace Evidence Analysis by : Vincent J. Desiderio

Download or read book Handbook of Trace Evidence Analysis written by Vincent J. Desiderio and published by John Wiley & Sons. This book was released on 2020-09-01 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Covers new trace evidence techniques and expanding areas of analysis, along with key theory and applications Developed around the need for updated information in the disciplines of trace evidence the Handbook of Trace Evidence Analysis focuses on the increasing awareness and need for validation, modern methods for addressing and controlling contamination, the shift towards incorporating statistical analyses into the interpretation phase and cutting edge research into new forensic science methods and their application. Beginning with an overview of the topic and discussing the important role that information derived from trace materials can provide during investigations, the book then presents chapters on key techniques. The first being the critical nature of microscopy, and the methods employed for the recognition, collection, and preservation of trace evidence. Subsequent chapters review the core disciplines of trace evidence examination: paints and polymers, hairs, fibers and textiles and glass. Each chapter contains in-depth discussions on the origin of the materials involved, including any natural or synthetic processes involved in their production, the nuances involved in their detection, and the methods of analysis that are used to extract valuable information from samples. In addition, suggested workflows in method and testing selections, as well as addressing specific scientific challenges as well as the limitations of knowledge on the transfer, persistence and background abundance of trace materials are discussed. The book ends by examining the interpretation of trace evidence findings from a historical perspective and examining the methods that are currently being developed. Provides an in-depth introduction to the general area of trace evidence and discusses current and new techniques Consolidates trace evidence and materials categories of testing into one reference series Offers a detailed focus on technical approaches and guidelines to trace evidence Includes analytical schemes/workflows and valuable guides for the interpretation of data and results The Handbook of Trace Evidence will appeal to forensic science academics, students, and practitioners in the trace evidence and materials science disciplines, as well as DNA analysts, toxicologists, forensic anthropologists, crime laboratory managers, criminal justice students and practitioners, and legal professionals. It would also be a valuable resource for every crime laboratory reference library.

Weight-of-Evidence for Forensic DNA Profiles

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 111881455X
Total Pages : 232 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Weight-of-Evidence for Forensic DNA Profiles by : David J. Balding

Download or read book Weight-of-Evidence for Forensic DNA Profiles written by David J. Balding and published by John Wiley & Sons. This book was released on 2015-07-20 with total page 232 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA evidence is widely used in the modern justice system. Statistical methodology plays a key role in ensuring that this evidence is collected, interpreted, analysed and presented correctly. This book is a guide to assessing DNA evidence and presenting that evidence in a courtroom setting. It offers practical guidance to forensic scientists with little dependence on mathematical ability, and provides the scientist with the understanding they require to apply the methods in their work. Since the publication of the first edition of this book in 2005 there have been many incremental changes, and one dramatic change which is the emergence of low template DNA (LTDNA) profiles. This second edition is edited and expanded to cover the basics of LTDNA technology. The author's own open-source R code likeLTD is described and used for worked examples in the book. Commercial and free software are also covered.

Weight-of-Evidence for Forensic DNA Profiles

Author : David J. Balding
Publisher : John Wiley & Sons
ISBN 13 : 0470867663
Total Pages : 198 pages
Book Rating : 4.4/5 (78 download)

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Book Synopsis Weight-of-Evidence for Forensic DNA Profiles by : David J. Balding

Download or read book Weight-of-Evidence for Forensic DNA Profiles written by David J. Balding and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 198 pages. Available in PDF, EPUB and Kindle. Book excerpt: Assessing Weight-of-Evidence for DNA Profiles is an excellent introductory text to the use of statistical analysis for assessing DNA evidence. It offers practical guidance to forensic scientists with little dependence on mathematical ability as the book includes background information on statistics – including likelihood ratios – population genetics, and courtroom issues. The author, who is highly experienced in this field, has illustrated the book throughout with his own experiences as well as providing a theoretical underpinning to the subject. It is an ideal choice for forensic scientists and lawyers, as well as statisticians and population geneticists with an interest in forensic science and DNA.

The Evaluation of Forensic DNA Evidence

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309121949
Total Pages : 271 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis The Evaluation of Forensic DNA Evidence by : National Research Council

Download or read book The Evaluation of Forensic DNA Evidence written by National Research Council and published by National Academies Press. This book was released on 1997-01-12 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments in population genetics and statistics since the original volume was published. The committee comments on statements in the original book that proved controversial or that have been misapplied in the courts. This volume offers recommendations for handling DNA samples, performing calculations, and other aspects of using DNA as a forensic toolâ€"modifying some recommendations presented in the 1992 volume. The update addresses two major areas: Determination of DNA profiles. The committee considers how laboratory errors (particularly false matches) can arise, how errors might be reduced, and how to take into account the fact that the error rate can never be reduced to zero. Interpretation of a finding that the DNA profile of a suspect or victim matches the evidence DNA. The committee addresses controversies in population genetics, exploring the problems that arise from the mixture of groups and subgroups in the American population and how this substructure can be accounted for in calculating frequencies. This volume examines statistical issues in interpreting frequencies as probabilities, including adjustments when a suspect is found through a database search. The committee includes a detailed discussion of what its recommendations would mean in the courtroom, with numerous case citations. By resolving several remaining issues in the evaluation of this increasingly important area of forensic evidence, this technical update will be important to forensic scientists and population geneticistsâ€"and helpful to attorneys, judges, and others who need to understand DNA and the law. Anyone working in laboratories and in the courts or anyone studying this issue should own this book.

Forensic DNA Profiling

Author : Jo-Anne Bright
Publisher : CRC Press
ISBN 13 : 0429671423
Total Pages : 132 pages
Book Rating : 4.4/5 (296 download)

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Book Synopsis Forensic DNA Profiling by : Jo-Anne Bright

Download or read book Forensic DNA Profiling written by Jo-Anne Bright and published by CRC Press. This book was released on 2019-12-09 with total page 132 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA testing and its forensic analysis are recognized as the “gold standard” in forensic identification science methods. However, there is a great need for a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a likelihood ratio, and how to use the subsequent likelihood ratio when reporting interpretation conclusions. Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios will provide a roadmap for labs all over the world and the next generation of analysts who need this foundational understanding. The techniques used in forensic DNA analysis are based upon the accepted principles of molecular biology. The interpretation of a good-quality DNA profile generated from a crime scene stain from a single-source donor provides an unambiguous result when using the most modern forensic DNA methods. Unfortunately, many crime scene profiles are not single source. They are described as mixed since they contain DNA from two or more individuals. Interpretation of DNA mixtures represents one of the greatest challenges to the forensic DNA analyst. As such, the book introduces terms used to describe DNA profiles and profile interpretation. Chapters explain DNA extraction methods, the polymerase chain reaction (PCR), capillary electrophoresis (CE), likelihood ratios (LRs) and their interpretation, and population genetic models—including Mendelian inheritance and Hardy-Weinberg equilibrium. It is important that analysts understand how LRs are generated in a probabilistic framework, ideally with an appreciation of both semicontinuous and fully continuous probabilistic approaches. KEY FEATURES: • The first book to focus entirely on DNA mixtures and the complexities involved with interpreting the results • Takes a hands-on approach offering theory with worked examples and exercises to be easily understood and implementable by laboratory personnel • New methods, heretofore unpublished previously, provide a means to innovate deconvoluting a mixed DNA profile, assign an LR, and appropriately report the weight of evidence • Includes a chapter on assigning LRs for close relatives (i.e., “It’s not me, it was my brother”), and discusses strategies for the validation of probabilistic genotyping software Forensic DNA Profiling fills the void for labs unfamiliar with LRs, and moving to probabilistic solutions, and for labs already familiar with LRs, but wishing to understand how they are calculated in more detail. The book will be a welcome read for lab professionals and technicians, students, and legal professionals seeking to understand and apply the techniques covered.

Forensic DNA Collection at Death Scenes

Author : Rhonda Williams, PhD., F-ABC
Publisher : CRC Press
ISBN 13 : 1482203707
Total Pages : 175 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis Forensic DNA Collection at Death Scenes by : Rhonda Williams, PhD., F-ABC

Download or read book Forensic DNA Collection at Death Scenes written by Rhonda Williams, PhD., F-ABC and published by CRC Press. This book was released on 2014-03-27 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt: DNA evidence collected from death scenes is an essential tool for law enforcement, death investigators, and forensic pathologists—providing insights into cause and manner of death as well as the identification of the responsible person or persons. Ineffective collection procedures raise the risk of evidence being altered or lost during transportation of the body. Using real death scene photos and actual cases as examples, Forensic DNA Collection at Death Scenes: A Pictorial Guide provides a practical approach to evidence collection with emphasis on proper identification, collection, documentation, and preservation. The first atlas of its kind, it demonstrates best practices for collecting DNA from decedents depending on the circumstances of the death scene and other materials present on the decedent such as clothing, bindings, and other objects. The authors discuss the success of the techniques employed in each scenario and analyze the DNA results obtained. The techniques employed at death scenes can also be applied to sexual assault cases, where DNA is collected from the body after an assault takes place. The increasing applications of evidence-based medicine and forensic science to criminal justice and civil litigation demand that crime scene investigations be more scientific, better organized, and multidisciplinary. This atlas provides a step-by-step guide to effective, uncompromising evidence collection.