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Fibroblasts
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Download or read book Molecular Biology of the Cell written by and published by . This book was released on 2002 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Heterogeneity of Cancer Metabolism by : Anne Le
Download or read book The Heterogeneity of Cancer Metabolism written by Anne Le and published by Springer. This book was released on 2018-06-26 with total page 186 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.
Download or read book Fibroblasts written by and published by BoD – Books on Demand. This book was released on 2021-12-22 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibroblasts - Advances in Inflammation, Autoimmunity and Cancer presents recent advances in understanding the roles of fibroblasts and mesenchymal stem cells in tissue homeostasis and the development of human disease. The book delves into general principles of fibroblast and mesenchymal stem cell biology and their diversity across the human body. It highlights these cells’ unique and shared characteristics across organs (e.g., vasculature, kidney, joints and exocrine glands) and specific pathologies (e.g., tissue damage, inflammation, fibrosis and cancer). A particular focus is set on the roles of fibroblasts in disease chronicity, recurrence, progression, therapeutic resistance and utilisation of the advancing knowledge for developing new therapeutic approaches within and beyond disease boundaries.
Book Synopsis Tumor-Associated Fibroblasts and their Matrix by : Margareta M. Mueller
Download or read book Tumor-Associated Fibroblasts and their Matrix written by Margareta M. Mueller and published by Springer Science & Business Media. This book was released on 2011-07-28 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 20 years it has become increasingly clear that the tumor micro-environment, the tumor stroma with its cellular end extracellular components, plays an crucial role in regulating tumor growth and progression. This book on “Tumor-associated fibroblasts and their matrix” as part of the series on “Tumor-Microenvironment” is the first comprehensive discussion of these two main players of the tumor microenvironment. The best experts in this new area of tumor research and therapy review the role of these major components in the tumor stroma in the process of tumor development and progression. They discuss their interaction with other players such as blood vessels and immune cells, and show novel perspectives for tumor therapy. This compilation of excellent contributions of the best known experts in this important field in cancer research and therapy is a must for all scientists engaged in basic and clinical research. Increasing evidence of successful targeting of both cellular and matrix components in tumor therapy renders this book of particular interest for scientists engaged in pharmaceutical industry searching for new components for cancer therapy.
Book Synopsis Human Stem Cell Manual by : Suzanne Peterson
Download or read book Human Stem Cell Manual written by Suzanne Peterson and published by Academic Press. This book was released on 2012-10-22 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt: This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. - Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications - Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America - Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs
Download or read book Dermal Fibroblasts written by Xiaowen Bai and published by Nova Science Publishers. This book was released on 2013 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Dermal fibroblasts are the most numerous cells within the dermal layer of skin. The main function of fibroblasts is to preserve the structural integrity of skin through constantly secreting extracellular matrix. Various factors diversely affect the secretion activities of fibroblasts and may lead to varying disease processes (eg: solar damage and wrinkles). This book gathers important cutting-edge research in the field of fibroblasts covering characterisation of fibroblasts and their roles in multiple disease processes such as hypertrophic scarring, ageing/photoaging, diabetic wound healing, cancer, and pachydermoperiostosis. In addition, the chapters also deal with the stem cell-like properties of fibroblasts, which sheds new light on the commonly used definition of fibroblasts and provides novel insights into many past studies performed with fibroblast preparations, since the reported effects might be greatly attributable to stem cell content within these fibroblasts. Additionally, this book features an introduction of the reprogramming of dermal fibroblasts into patient-specific induced pluripotent stem cells (iPSCs) that can be converted into varying terminally differentiated cells. Application of iPSCs is a rapidly developing research field because reprogrammed iPSCs from dermal fibroblasts provides a great tool for studying molecular mechanisms of disease, development, and tissue regeneration. This book is certain to have broad appeal and should provide a useful resource for researchers, students, teachers, and physicians interested in the field.
Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge
Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.
Book Synopsis Innovative Medicine by : Kazuwa Nakao
Download or read book Innovative Medicine written by Kazuwa Nakao and published by Springer. This book was released on 2015-10-13 with total page 330 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Book Synopsis General Histology of the Mammal by : Radivoj V. Krstic
Download or read book General Histology of the Mammal written by Radivoj V. Krstic and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 689 pages. Available in PDF, EPUB and Kindle. Book excerpt: With a Foreword by Reiter R.J. Translated by Forster, S.
Book Synopsis Skin Tissue Engineering by : Sophie Böttcher-Haberzeth
Download or read book Skin Tissue Engineering written by Sophie Böttcher-Haberzeth and published by Springer Nature. This book was released on 2019-05-30 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides protocols describing the isolation and culture of diverse cell types stemming from the skin and the use of these cells and cell constructs for wound healing, bioengineering applications, and translational medicine purposes. The book is divided into three sections describing the isolation and culture of diverse skin cells, managing these cells within co-culture systems and skin models, as well as using these skin models in a test setting. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Skin Tissue Engineering: Methods and Protocols serves as a vital aid to basic and clinical researchers such as biologists, physicians, and biomedical engineers working with and being interested in basic science, and clinically and laboratory-applicable translational regenerative medicine.
Book Synopsis Vascular Biology of the Placenta by : Yuping Wang
Download or read book Vascular Biology of the Placenta written by Yuping Wang and published by Biota Publishing. This book was released on 2017-06-23 with total page 126 pages. Available in PDF, EPUB and Kindle. Book excerpt: The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.
Book Synopsis Tissue Repair, Contraction and the Myofibroblast by : Christine Chaponnier
Download or read book Tissue Repair, Contraction and the Myofibroblast written by Christine Chaponnier and published by Springer Science & Business Media. This book was released on 2007-02-26 with total page 154 pages. Available in PDF, EPUB and Kindle. Book excerpt: Tissue Repair, Contraction and the Myofibroblast summarizes the latest findings concerning the biology of the myofibroblast, a cell involved in the evolution and contraction of granulation tissue and of fibrotic changes. Coverage shows that the myofibroblast is responsible for the development of hypertrophic scars, pulmonary and renal fibrosis and bronchial asthma. Reviews the cell biology and pathology of the myofibroblast as well as mechanisms of fibrosis evolution in many organs and tissues.
Book Synopsis Stem Cells and the Future of Regenerative Medicine by : Institute of Medicine
Download or read book Stem Cells and the Future of Regenerative Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2002-01-25 with total page 112 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush's watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.
Book Synopsis Report of Workshop on the Fibroblast in Interstitial Lung Diseases by :
Download or read book Report of Workshop on the Fibroblast in Interstitial Lung Diseases written by and published by . This book was released on 1984 with total page 34 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fibroblast Growth Factors by : Xiaokun Li
Download or read book Fibroblast Growth Factors written by Xiaokun Li and published by Elsevier. This book was released on 2023-11-16 with total page 1034 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fibroblast Growth Factors, Second Edition systematically introduces readers to FGF in the fields of injury repair and regeneration, endocrinology and metabolism, structure and modification, pharmaceutics, pharmacology, FGF/FGFR inhibitor, engineering and new drug development. Fibroblast growth factors (FGFs) are secreted protein ligands that act in a paracrine or endocrine fashion to carry out their pleiotropic functions in development, tissue homeostasis and metabolism. This book covers the work from Li's team from 2013 to 2018 and will be a primer for scientists, particularly young students entering the FGFs field with an eye on basic research and application. - Contains approximately 90% new material on topics covered - Includes information on "breakthrough discoveries which have been made since the publication of the first edition - Introduces detailed research methods and technologies of FGFs so the book can be used as a "toolbox by the user - Includes comprehensive and systematic research and industry application
Book Synopsis Fibroblast Activation Protein Imaging, An Issue of PET Clinics, E-Book by : Frederik L. Giesel
Download or read book Fibroblast Activation Protein Imaging, An Issue of PET Clinics, E-Book written by Frederik L. Giesel and published by Elsevier Health Sciences. This book was released on 2023-06-01 with total page 177 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this issue, guest editors bring their considerable expertise to this important topic. - Contains 16 practice-oriented topics including fibroblast activation protein inhibitor (FAPI) PET imaging in pancreatic cancer; fibroblast activation protein inhibitor (FAPI) PET imaging in colorectal cancer; fibroblast activation protein inhibitor (FAPI) cardiac imaging; fibroblast activation protein inhibitor (FAPI) PET/CT in gastric cancer; and more. - Provides in-depth clinical reviews on fibroblast activation protein imaging, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Book Synopsis Minimally Invasive Aesthetic Procedures by : Adilson Da Costa
Download or read book Minimally Invasive Aesthetic Procedures written by Adilson Da Costa and published by Springer Nature. This book was released on 2020-02-24 with total page 785 pages. Available in PDF, EPUB and Kindle. Book excerpt: Minimally invasive aesthetic procedures are an important part of dermatologists’ day-to-day clinical routine. However, plastic surgeons are also becoming more willing to explore them, and minimally invasive cosmetic and aesthetic procedures are now an established interdisciplinary topic. Minimally Invasive Aesthetic Procedures - A Guide for Dermatologists and Plastic Surgeons addresses the needs of both these specialties. It provides a comprehensive overview of the most relevant and widely used minimally invasive procedures, presented in a practical and straightforward style. Rather than a broad overview of the literature, it offers a step-by-step guide to clinical procedures. Each chapter explores a single clinical procedure, discussing the theoretical basis; the materials needed; the methods and techniques; clinical follow-up; before-and-after illustrations; as well as the side effects and complications and their management. It also includes a summary of tips and relevant references. With more than a hundred procedures presented and discussed in a clinically applicable format, Minimally Invasive Aesthetic Procedures - A Guide for Dermatologists and Plastic Surgeons is a practical manual for all dermatology and plastic surgery practitioners who are interested in aesthetic medicine.