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Fast Facts Car T Cell Therapy In Diffuse Large B Cell Lymphoma
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Book Synopsis Fast Facts: CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma by : Richard J. Buka
Download or read book Fast Facts: CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma written by Richard J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-10-31 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse large B-cell lymphoma (DLBCL) is the most common form of high-grade non-Hodgkin lymphoma. While treatment with immunochemotherapy has generally shown good outcomes, specific subgroups of patients with high-risk disease have an unfavorable prognosis. Extensive efforts have been made to improve outcomes in these patients. As such, CD19-targeted chimeric antigen receptor (CAR) T-cell therapy has become the new standard of care for patients with relapsed or refractory DLBCL after at least two prior lines of therapy. It is an exciting new therapeutic intervention that is integral to the concept of personalized medicine. Table of Contents: • DLBCL: an overview • CAR T cells • CAR T-cell products • Delivering CAR T-cell therapy and managing patient expectations • CAR T-cell therapy-related toxicities
Book Synopsis Fast Facts: CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma by : R.J. Buka
Download or read book Fast Facts: CAR T-Cell Therapy in Diffuse Large B-Cell Lymphoma written by R.J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-09-30 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diffuse large B-cell lymphoma (DLBCL) is the most common form of high-grade non-Hodgkin lymphoma. While treatment with immunochemotherapy has generally shown good outcomes, specific subgroups of patients with high-risk disease have an unfavorable prognosis. Extensive efforts have been made to improve outcomes in these patients. As such, CD19-targeted chimeric antigen receptor (CAR) T-cell therapy has become the new standard of care for patients with relapsed or refractory DLBCL after at least two prior lines of therapy. It is an exciting new therapeutic intervention that is integral to the concept of personalized medicine. Table of Contents: • DLBCL: an overview • CAR T cells • CAR T-cell products • Delivering CAR T-cell therapy and managing patient expectations • CAR T-cell therapy-related toxicities
Book Synopsis Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book by : Daniel W. Lee
Download or read book Chimeric Antigen Receptor T-Cell Therapies for Cancer E-Book written by Daniel W. Lee and published by Elsevier Health Sciences. This book was released on 2019-11-30 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali N. Shah, this clinical resource keeps you up to date on the latest developments in this rapidly evolving area. - Covers all clinical aspects, including patient referral, toxicities management, comorbidities, bridging therapy, post-CAR monitoring, and multidisciplinary approaches to supportive care. - Includes key topics on associated toxicities such as predictive biomarkers, infections, and multidisciplinary approaches to supportive care. - Presents current knowledge on FDA approved CAR T-cell products as well as developments on the horizon. - Editors and authors represent leading investigators in academia and worldwide pioneers of CAR therapy.
Book Synopsis Fast Facts: CAR T-Cell Therapy by : Richard J. Buka
Download or read book Fast Facts: CAR T-Cell Therapy written by Richard J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-02-28 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells are and how they were developed, discusses the results of clinical trials and the management of toxicities, and outlines future improvements and applications. It is ideal reading for any healthcare professional wanting to know more about this exciting therapeutic field. Table of Contents: • CAR T cells • Clinical application • Practical aspects • Future directions
Author :Graham P. Collins Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318072869 Total Pages :188 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Lymphoma by : Graham P. Collins
Download or read book Fast Facts: Lymphoma written by Graham P. Collins and published by Karger Medical and Scientific Publishers. This book was released on 2023-07-20 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: Lymphoma can be broadly defined as a cancer of mature lymphocytes. Our understanding of the biology of normal lymphocytes and lymphoma has grown at a tremendous pace, and this is now directly translating into changes in clinical practice. This became evident with the introduction of one of the first therapeutic monoclonal antibodies into cancer medicine, the CD20-directed antibody rituximab, which has led to significant benefit for patients with B-cell lymphomas. Since then, a raft of novel agents has entered clinical practice, including targeted small molecules, antibody-drug conjugates, bispecific antibodies, and chimeric antigen receptor (CAR) T cells. This new edition of 'Fast Facts: Lymphoma' has been updated to include recent changes in our understanding of lymphoma biology as well as improvements in diagnostics and therapeutics.
Book Synopsis Blood and Marrow Transplant Handbook by : Richard T. Maziarz
Download or read book Blood and Marrow Transplant Handbook written by Richard T. Maziarz and published by Springer. This book was released on 2015-04-20 with total page 437 pages. Available in PDF, EPUB and Kindle. Book excerpt: This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook includes indications for transplantation and donor selection, treatment guidelines for addressing complications during and after transplant, and recommendations for long-term follow up care. Concise, comprehensive, and easy-to-use, Blood and Marrow Transplant Handbook, 2nd Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers who care for transplant patients, and also residents, fellows, and other trainees.
Book Synopsis Fast Facts: Immuno-Oncology by : S. Clarke
Download or read book Fast Facts: Immuno-Oncology written by S. Clarke and published by Karger Medical and Scientific Publishers. This book was released on 2021-06-29 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology
Book Synopsis Fast Facts: Gene Therapy by : R. Herzog
Download or read book Fast Facts: Gene Therapy written by R. Herzog and published by Karger Medical and Scientific Publishers. This book was released on 2020-04-24 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Gene therapy has emerged as a discipline in medicine that can provide treatments for diseases that have no other therapies available, save lives of patients for whom there is no other hope and replace suboptimal treatments with lasting cures. 'Fast Facts: Gene Therapy' provides an overview of the field, looking at the main vector systems used to transfer the therapeutic gene constructs, the molecular mechanisms and the history of gene therapy, as well as the safety and ethical considerations of this important advance. Multiple examples of diseases that are already successfully treated with gene therapy are given, with discussion of treatments that hold promise for the future. This book will be informative and of value to health professionals, researchers, students and anyone with an interest in this exciting and fast-moving area. Contents: • Principles of gene therapy • Gene therapy techniques • Ethical and safety considerations • Gene therapies with proven clinical efficacy • Genome editing • Research directions – the next wave of treatments
Book Synopsis Guidelines for Preparing Patent Landscape Reports by : World Intellectual Property Organization
Download or read book Guidelines for Preparing Patent Landscape Reports written by World Intellectual Property Organization and published by WIPO. This book was released on 2015-08-24 with total page 131 pages. Available in PDF, EPUB and Kindle. Book excerpt: These Guidelines are designed both for general users of patent information, as well as for those involved in producing Patent Landscape Reports (PLRs). They provide step-by-step instructions on how to prepare a PLR, as well as background information such as objectives, patent analytics, concepts and frameworks.
Book Synopsis Cancer Immunology and Immunotherapy by : Mansoor M. Amiji
Download or read book Cancer Immunology and Immunotherapy written by Mansoor M. Amiji and published by Academic Press. This book was released on 2021-08-18 with total page 550 pages. Available in PDF, EPUB and Kindle. Book excerpt: Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side. - Comprehensive treaty covering all aspects of immuno-oncology (IO) - Novel strategies for delivery of IO therapeutics and vaccines - Forecasting on the future of nanotechnology and drug delivery for IO
Book Synopsis Fast Facts: Marginal Zone Lymphoma by : Shirly D'Sa
Download or read book Fast Facts: Marginal Zone Lymphoma written by Shirly D'Sa and published by Karger Medical and Scientific Publishers. This book was released on 2024-08-13 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Marginal Zone Lymphoma' provides an overview of MZL for healthcare professionals and others with an interest in this blood cancer. It summarizes what is known about the pathophysiology of the disease, and discusses the importance of accurate diagnosis, staging, and prognosis, together with existing approaches to treatment and monitoring, including the latest evidence for new therapies in the R/R setting. With an eye to the future, it also reviews some of the therapies in development, which may ultimately improve quality of life and ensure better outcomes for patients with MZL.
Author :Allan Hackshaw Publisher :Karger Medical and Scientific Publishers ISBN 13 :1912776731 Total Pages :120 pages Book Rating :4.9/5 (127 download)
Book Synopsis Fast Facts: Clinical Trials in Oncology by : Allan Hackshaw
Download or read book Fast Facts: Clinical Trials in Oncology written by Allan Hackshaw and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-18 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted. Contents: • Fundamental features of clinical trials • Phase I trials • Phase II trials • Phase III trials • Trials of non-drug interventions • Setting up and conducting trials • Publishing trial results, changing clinical practice, and supporting evidence
Book Synopsis Developing Costimulatory Molecules for Immunotherapy of Diseases by : Manzoor Ahmad Mir
Download or read book Developing Costimulatory Molecules for Immunotherapy of Diseases written by Manzoor Ahmad Mir and published by Academic Press. This book was released on 2015-05-25 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families, with the hope that targeting these families will yield new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases. - Highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy - Provides the latest information on the complex roles and interactions within the CD28 and B7 costimulatory families - Targets new therapies for the treatment of inflammation, autoimmunity, transplantation, cancer, and other infectious diseases
Book Synopsis Fast Facts: Follicular Lymphoma by : Pamela McKay
Download or read book Fast Facts: Follicular Lymphoma written by Pamela McKay and published by Karger Medical and Scientific Publishers. This book was released on 2024-06-07 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Follicular Lymphoma' provides an introduction to follicular lymphoma for healthcare professionals and others with an interest in this blood cancer. It summarizes what is known about the pathophysiology of the disease, and discusses the importance of accurate diagnosis, classification, and risk assessment, together with existing approaches to treatment and monitoring. Looking into the future, it also reviews some of the therapies in development, which may ultimately improve quality of life and ensure better outcomes for patients with FL.
Book Synopsis The EBMT/EHA CAR-T Cell Handbook by : Nicolaus Kröger
Download or read book The EBMT/EHA CAR-T Cell Handbook written by Nicolaus Kröger and published by Springer Nature. This book was released on 2022-02-07 with total page 221 pages. Available in PDF, EPUB and Kindle. Book excerpt: This first open access European CAR-T Handbook, co-promoted by the European Society for Blood and Marrow Transplantation (EBMT) and the European Hematology Association (EHA), covers several aspects of CAR-T cell treatments, including the underlying biology, indications, management of side-effects, access and manufacturing issues. This book, written by leading experts in the field to enhance readers’ knowledge and practice skills, provides an unparalleled overview of the CAR-T cell technology and its application in clinical care, to enhance readers’ knowledge and practice skills.
Book Synopsis Fast Facts: Chronic Lymphocytic Leukemia by : T.A. Eyre
Download or read book Fast Facts: Chronic Lymphocytic Leukemia written by T.A. Eyre and published by Karger Medical and Scientific Publishers. This book was released on 2022-02-11 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chronic lymphocytic leukemia (CLL) is the most diagnosed leukemia in the Western world, accounting for approximately 25% of all new leukemia diagnoses. In recent years, remarkable progress has been made in our understanding of both the pathophysiology and genetics of CLL. While the disease generally affects older adults and initially follows an indolent course, cytogenetic and molecular profiling have helped to predict clinical outcomes. Greater prognostication, alongside the development of an increasing armamentarium of novel targeted therapies, has enabled us to provide more personalized management options for patients. 'Fast Facts: Chronic Lymphocytic Leukemia' covers the epidemiology, etiology, diagnosis and staging of the disease, and the molecular and genetic aspects that underpin treatment and prognosis. It provides a concise overview of treatment options, in both the front-line and relapsed/refractory settings, with particular focus on the novel targeted agents that have overcome many adverse prognostic factors, improving overall survival. Table of Contents: • Epidemiology and etiology • Molecular biology and genetics • Diagnosis, staging and prognosis • Management • Research directions
Book Synopsis Cutaneous T-Cell Lymphoma by : Herschel S. Zackheim
Download or read book Cutaneous T-Cell Lymphoma written by Herschel S. Zackheim and published by CRC Press. This book was released on 2004-10-28 with total page 155 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cutaneous T-cell lymphoma (CTCL) is a general term for many lymphomas of the skin including mycosis Fungoides and Sezary syndrome. This book presents the state of the art in CTCL epidemiology, clinical features, pathology, immunochemistry, diagnostic molecular techniques, staging and prognosis, and treatment. Edited by one of the leading experts in
