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Fast Facts Clinical Trials In Oncology
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Book Synopsis Fast Facts: Clinical Trials in Oncology by : A. Hackshaw
Download or read book Fast Facts: Clinical Trials in Oncology written by A. Hackshaw and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-18 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted.
Book Synopsis Fast Facts : Clinical Trials in Oncology by : Allan Hackshaw
Download or read book Fast Facts : Clinical Trials in Oncology written by Allan Hackshaw and published by . This book was released on 2021 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Fast Facts: Medical Statistics by : R. Kay
Download or read book Fast Facts: Medical Statistics written by R. Kay and published by Karger Medical and Scientific Publishers. This book was released on 2020-07-17 with total page 110 pages. Available in PDF, EPUB and Kindle. Book excerpt: Using real examples from oncology trials, but keeping it simple, this concise resource explains the basic principles of medical statistics so that you can better appraise clinical trial results. Key concepts covered in this book include: • hypothesis testing • Kaplan–Meier curves and other graphic representations of data • calculating the power of a study • the stopping rules for efficacy and futility. ' Fast Facts: Medical Statistics' is aimed at all clinicians, clinical scientists, medical writers and regulatory personnel who need a better understanding of the statistical terms and methods used in the planning of studies and the analysis of clinical trial data. If you have ever wanted to know what a type I error is, how an odds ratio is calculated or what a forest plot is really all about, then this is the book for you. Contents: • Statistical inference • Analysis of time-to-event endpoints • Power and sample size • Multiplicity • Interim analysis • Modeling • Graphical methods
Book Synopsis Fast Facts: Immuno-Oncology by : Stephen Clarke
Download or read book Fast Facts: Immuno-Oncology written by Stephen Clarke and published by Karger Medical and Scientific Publishers. This book was released on 2021-07-07 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment of cancer has been revolutionized by therapies that modulate the immune system, with benefits for quality of life and survival. Standards of care have changed to reflect developments, but the area is moving fast. Keeping abreast of new therapies and trial data can be challenging. This second edition of 'Fast Facts: Immuno-Oncology' takes you from the fundamentals of immunology through to the new concepts of immunoediting and immunotherapy and likely future directions. Whether you have worked in oncology for decades and need a refresher or you are just starting out and need a crash course, this book provides all you need to know about immuno-oncology, concisely summarized. Table of Contents: • Components of the immune system • How cancers evade the immune system • How cancer immunotherapy works • Clinical use of immune checkpoint inhibitors • The future of immuno-oncology
Book Synopsis Fast Facts: Breast Cancer by : Jayant Sharad Vaidya
Download or read book Fast Facts: Breast Cancer written by Jayant Sharad Vaidya and published by . This book was released on 2014-06-02 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wherever you are in your career, and whatever involvement you have with caring for women with breast cancer, the fifth edition of 'Fast Facts: Breast Cancer' has something for you. The world-class authors of this popular fact-packed handbook provide practical advice on all the key areas of breast cancer management, from risk factors and diagnosis to treatment of all cancer stages. But what really makes it stand out from the crowd is the authors' awareness of the information you need when you talk to a woman concerned about breast cancer. The chapter dedicated to perception of risk will refresh your knowledge and help you talk to your patients about their individual prospects, while the short chapter on clinical trials will help you discuss potential participation in trials and answer common questions. Improvements in the management of breast cancer have followed three major themes in recent years: greater optimization of individualized local treatment, longer duration of therapies, and the use of biological therapies targeted at specific receptors. This colorful up-to-date handbook addresses all these trends, alongside the disturbing issues of overdiagnosis as a result of screening and overtreatment. Given the explosion in information technology, patients and their families have access to much more information on their condition and as a result assume a more active role in their medical management. Health professionals have an important role in helping patients sort the facts from the fallacies, put the risks and benefits into perspective and balance their treatment choices. For this reason alone, 'Fast Facts: Breast Cancer' is an invaluable evidence-based resource for everyone working in breast cancer care in primary and secondary settings, from medical and nursing students, to GPs, specialist nurses and residents. And one for your patients too ... The authors encourage you to make your patients well-informed active partners in their breast cancer care by sharing this highly readable book with them. Contents: * Risk factors * Perception of risk * Pathophysiology * Diagnosis * Local control of primary tumor * Adjuvant therapy * Follow-up and rehabilitation * Management of advanced cancer * Clinical trials * Future trends * Useful resources
Book Synopsis Clinical Trials in Oncology, Third Edition by : Stephanie Green
Download or read book Clinical Trials in Oncology, Third Edition written by Stephanie Green and published by CRC Press. This book was released on 2012-05-09 with total page 266 pages. Available in PDF, EPUB and Kindle. Book excerpt: The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the pitfalls inherent in these processes. In addition, the book has been restructured to have separate chapters and expanded discussions on general clinical trials issues, and issues specific to Phases I, II, and III. New sections cover innovations in Phase I designs, randomized Phase II designs, and overcoming the challenges of array data. Although this book focuses on cancer trials, the same issues and concepts are important in any clinical setting. As always, the authors use clear, lucid prose and a multitude of real-world examples to convey the principles of successful trials without the need for a strong statistics or mathematics background. Armed with Clinical Trials in Oncology, Third Edition, clinicians and statisticians can avoid the many hazards that can jeopardize the success of a trial.
Download or read book Breast Cancer written by Jayant S. Vaidya and published by . This book was released on 2010 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This colourful, comprehensive yet compact handbook covers the key areas of breast cancer management, from risk factors and diagnosis to management of all cancer stages. But what really makes this book stand out from the crowd is the authors' awareness of just what information you need when you talk to a woman concerned about breast cancer. The chapter dedicated to risk will refresh your knowledge and help you talk to your patients about their individual risk. And the short chapter on clinical trials will help you discuss potential participation in trials and answer common questions. Wherever you are in your career, and whatever involvement you have with caring for women with breast cancer, this book will have something for you.
Author :Allan Hackshaw Publisher :Karger Medical and Scientific Publishers ISBN 13 :1912776731 Total Pages :120 pages Book Rating :4.9/5 (127 download)
Book Synopsis Fast Facts: Clinical Trials in Oncology by : Allan Hackshaw
Download or read book Fast Facts: Clinical Trials in Oncology written by Allan Hackshaw and published by Karger Medical and Scientific Publishers. This book was released on 2020-12-18 with total page 120 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by leading experts, 'Fast Facts: Clinical Trials in Oncology' will enhance the reader’s ability to critically evaluate published evidence. Assuming little or no prior knowledge, the book sets out clearly the fundamental features of clinical trials. The key attributes of Phase I–III trials of pharmaceutical products are described, as are trials of surgical procedures, radiation therapy and advanced therapies. The processes and documentation required to set up and conduct a trial are outlined, and the authors describe how trial data and real-world evidence are used to improve care. Although this concise colorful book focuses on oncology, the principles apply equally to interventions in other areas of practice. It will prove invaluable to medical, pharmaceutical and allied health professionals who want, or need, an overview of how contemporary clinical trials are designed and conducted. Contents: • Fundamental features of clinical trials • Phase I trials • Phase II trials • Phase III trials • Trials of non-drug interventions • Setting up and conducting trials • Publishing trial results, changing clinical practice, and supporting evidence
Author :Jayant S. Vaidya Publisher :Karger Medical and Scientific Publishers ISBN 13 :191079712X Total Pages :74 pages Book Rating :4.9/5 (17 download)
Book Synopsis Fast Facts: Early Breast Cancer by : Jayant S. Vaidya
Download or read book Fast Facts: Early Breast Cancer written by Jayant S. Vaidya and published by Karger Medical and Scientific Publishers. This book was released on 2016-12-01 with total page 74 pages. Available in PDF, EPUB and Kindle. Book excerpt: 'Fast Facts: Early Breast Cancer' provides a comprehensive overview of stage 0, I, II and IIIA disease, including the latest thinking on the risk of developing breast cancer and the value (or not) of screening, alongside the importance of clinical staging and triple assessment. Using clear diagnostic and management pathways, this practical resource covers: · the risks and benefits of neadjuvant treatment · surgical and reconstruction options · the latest approach to radiotherapy · when and how to select the correct adjuvant therapy · guidelines for follow-up and rehabilitation. 'Fast Facts: Early Breast Cancer' is an invaluable resource that draws on current evidence to assist everyone working in breast cancer care improve patient outcomes.
Book Synopsis Fast Facts: Digital Medicine - Measurement by : Andrea Coravos
Download or read book Fast Facts: Digital Medicine - Measurement written by Andrea Coravos and published by Karger Medical and Scientific Publishers. This book was released on 2020-03-31 with total page 98 pages. Available in PDF, EPUB and Kindle. Book excerpt: Technology is changing how we practice medicine. Sensors and wearables are getting smaller and cheaper, and algorithms are becoming powerful enough to predict medical outcomes. Yet despite rapid advances, healthcare lags behind other industries in truly putting these technologies to use. A major barrier is the cross-disciplinary approach required to create digital tools, a process that requires knowledge from many people across a range of fields. 'Fast Facts: Digital Medicine – Measurement' aims to overcome that barrier, introducing the reader to core concepts and terms and facilitating dialogue. Contrasting 'clinical research' with routine 'clinical care', this short colorful book describes types of digital measurement and how to use and validate digital measures in different settings. And with the burgeoning development of digital medicine tools, the authors provide a timely overview of the security, ethical, regulatory and legal issues to be considered before a product can enter the market. Table of Contents: • What is digital medicine? • Where does digital medicine fit? • Regulatory considerations • Ethical principles and our responsibilities • Ethics in practice • Security, data rights and governance • Digital biomarkers and clinical outcomes • Measurement in clinical trials • Verification and validation • The future of digital medicine
Book Synopsis Fast Facts: Non-Small-Cell Lung Cancer by : Mary O'Brien
Download or read book Fast Facts: Non-Small-Cell Lung Cancer written by Mary O'Brien and published by Karger Medical and Scientific Publishers. This book was released on 2016-08-22 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: Rapid developments in the classification, screening and treatment of non-small-cell lung cancer (NSCLC) are improving outcomes for patients with the disease. This insightful guide is designed to bring you up to speed with recent advances, including: • the latest CT-based screening and interval growth imaging techniques • proposed changes to the TNM classification system • the increasing trend for minimally invasive and lung-sparing surgery • stereotactic radiation for early-stage tumors • new targeted therapies • breakthroughs in personalized medicine. Today's developments will change tomorrow's standards of care. 'Fast Facts: Non-Small-Cell Lung Cancer' is important reading for all health professionals and medical trainees working in this fast-moving area.
Author :Christina Fotopoulou Publisher :Karger Medical and Scientific Publishers ISBN 13 :191079743X Total Pages :105 pages Book Rating :4.9/5 (17 download)
Book Synopsis Fast Facts: Ovarian Cancer by : Christina Fotopoulou
Download or read book Fast Facts: Ovarian Cancer written by Christina Fotopoulou and published by Karger Medical and Scientific Publishers. This book was released on 2017-05-09 with total page 105 pages. Available in PDF, EPUB and Kindle. Book excerpt: When it comes to detecting, diagnosing and treating women who have, or are suspected of having, ovarian cancer, there are significant opportunities for well-informed healthcare professionals to intervene in a meaningful way. 'Fast Facts: Ovarian Cancer' examines the areas that will have the biggest effect in clinical practice, including: • the evidence for and against screening • the valuable role of genetic testing in identifying at-risk women • if and when to operate • strategies to overcome platinum resistance • the impact of targeted therapies. From the tools that will help establish a swift diagnosis to the risks and benefits of palliative salvage surgery, this refreshingly readable resource captures the key knowledge that every busy healthcare professional needs in order to make better health decisions for patients with ovarian cancer. Contents: • Epidemiology and prevention • Pathophysiology and classification • Genetic testing • Diagnosis, staging and grading • Surgery • Chemotherapy • Recurrent ovarian cancer • Targeted therapies • Non-epithelial ovarian cancers • Follow-up and palliative surgery • Useful resources
Download or read book Immuno-Oncology written by O. Michielin and published by Karger Medical and Scientific Publishers. This book was released on 2015-09-09 with total page 140 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last decade, immuno-oncology has witnessed an astonishing pace of discovery and innovation translating into unprecedented successes in the clinical setting, arguably representing one of the most profound and transforming revolution in the history of cancer therapy. This book provides a concise and accurate outline of the main developments in major tumor types including melanoma, lung, breast, brain and renal cell cancers. In addition, transversal chapters that describe the commonalities of some of the therapeutic strategies are provided to cover topics like immune checkpoint biology, T cell engineering or rational combination therapies. Each chapter has been authored by senior key opinion leaders in their respective fields to provide the most up-to-date view on cancer immuno-oncology. To reflect on the key translational aspect of immuno-oncology, all chapters are making explicit connections between basic science discoveries and the resulting translational therapeutic strategies. Immuno-Oncology will be an invaluable source of information for scientists interested in the translation of basic immunology into the clinical practice, as well as for clinician interested in deepening their knowledge of current and upcoming immune strategies in the fight against cancers.
Book Synopsis Transforming Clinical Research in the United States by : Institute of Medicine
Download or read book Transforming Clinical Research in the United States written by Institute of Medicine and published by National Academies Press. This book was released on 2010-10-22 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.
Author :Bernardo L. Rapoport Publisher :Karger Medical and Scientific Publishers ISBN 13 :3318068187 Total Pages :109 pages Book Rating :4.3/5 (18 download)
Book Synopsis Fast Facts: Comprehensive Genomic Profiling by : Bernardo L. Rapoport
Download or read book Fast Facts: Comprehensive Genomic Profiling written by Bernardo L. Rapoport and published by Karger Medical and Scientific Publishers. This book was released on 2020-10-20 with total page 109 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cancer is a multifaceted disease in which genetic changes induce uncontrolled tumor growth. Genomic characterization of cancer is now leading to better diagnostic, prognostic and predictive biomarkers, and effective individualized management. 'Fast Facts: Comprehensive Genomic Profiling' provides a crash course in the science, methods and application of genomic profiling. Assuming only the most basic knowledge – or memory – of cell biology, the authors provide an overview of DNA and RNA biology and next-generation sequencing. This sets in context the descriptions of prognostic and predictive biomarkers for different cancer types and genomic-based treatments. Finally, but importantly, some of the practicalities of gaining and interpreting genomic information are described. Whether you need a primer or a refresher, this short colorful book demystifies this complex subject. Contents: • Genetic mutations and biomarkers • Understanding next-generation sequencing • Elements of comprehensive genomic profiles • Role in precision oncology • Predictive and prognostic biomarkers • Overcoming barriers to genotype-directed therapy
Book Synopsis Fast Facts: Molecular Profiling in Solid Tumors by : P. Cheema
Download or read book Fast Facts: Molecular Profiling in Solid Tumors written by P. Cheema and published by Karger Medical and Scientific Publishers. This book was released on 2022-12-06 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Identifying tumor-specific molecular aberrations via molecular profiling is vital for the use of targeted therapies. Understanding a patient’s unique tumor genetics provides predictive and prognostic information that enables a personalized care plan to be put in place, improving outcomes and minimizing ineffective treatments. 'Fast Facts: Molecular Profiling in Solid Tumors' provides a firm knowledge foundation of somatic molecular profiling methodologies, key information to help with the use of molecular profiling in daily practice and advice on communicating with patients about molecular testing and results. Table of Contents: • Molecular profiling: the basics • Rationale for testing • Sample collection • Test selection and process • Interpreting the report • Talking to patients • Challenges and opportunities
Book Synopsis Fast Facts: CAR T-Cell Therapy by : Richard J. Buka
Download or read book Fast Facts: CAR T-Cell Therapy written by Richard J. Buka and published by Karger Medical and Scientific Publishers. This book was released on 2021-02-28 with total page 71 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells are and how they were developed, discusses the results of clinical trials and the management of toxicities, and outlines future improvements and applications. It is ideal reading for any healthcare professional wanting to know more about this exciting therapeutic field. Table of Contents: • CAR T cells • Clinical application • Practical aspects • Future directions
