Extending The Human Life Span

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Extra Life

Author : Steven Johnson
Publisher : Penguin
ISBN 13 : 0525538879
Total Pages : 320 pages
Book Rating : 4.5/5 (255 download)

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Book Synopsis Extra Life by : Steven Johnson

Download or read book Extra Life written by Steven Johnson and published by Penguin. This book was released on 2021-05-11 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: “Offers a useful reminder of the role of modern science in fundamentally transforming all of our lives.” —President Barack Obama (on Twitter) “An important book.” —Steven Pinker, The New York Times Book Review The surprising and important story of how humans gained what amounts to an extra life, from the bestselling author of How We Got to Now and Where Good Ideas Come From In 1920, at the end of the last major pandemic, global life expectancy was just over forty years. Today, in many parts of the world, human beings can expect to live more than eighty years. As a species we have doubled our life expectancy in just one century. There are few measures of human progress more astonishing than this increased longevity. Extra Life is Steven Johnson’s attempt to understand where that progress came from, telling the epic story of one of humanity’s greatest achievements. How many of those extra years came from vaccines, or the decrease in famines, or seatbelts? What are the forces that now keep us alive longer? Behind each breakthrough lies an inspiring story of cooperative innovation, of brilliant thinkers bolstered by strong systems of public support and collaborative networks, and of dedicated activists fighting for meaningful reform. But for all its focus on positive change, this book is also a reminder that meaningful gaps in life expectancy still exist, and that new threats loom on the horizon, as the COVID-19 pandemic has made clear. How do we avoid decreases in life expectancy as our public health systems face unprecedented challenges? What current technologies or interventions that could reduce the impact of future crises are we somehow ignoring? A study in how meaningful change happens in society, Extra Life celebrates the enduring power of common goals and public resources, and the heroes of public health and medicine too often ignored in popular accounts of our history. This is the sweeping story of a revolution with immense public and personal consequences: the doubling of the human life span.

Coping with Methuselah

Author : Henry Aaron
Publisher : Rowman & Littlefield
ISBN 13 : 9780815796305
Total Pages : 316 pages
Book Rating : 4.7/5 (963 download)

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Book Synopsis Coping with Methuselah by : Henry Aaron

Download or read book Coping with Methuselah written by Henry Aaron and published by Rowman & Littlefield. This book was released on 2004-01-20 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: Many medical authorities predict that average life expectancy could well exceed 100 years by mid century and rise even higher soon thereafter. This astonishing prospect, brought on by the revolution in molecular biology and information technology, confronts policymakers and public health officials with a host of new questions. How will increased longevity affect local and global demographic trends, government taxation and spending, health care, the workplace, Social Security, Medicare, and Medicaid? What ethical and quality-of-life issues are raised by these new breakthroughs? In Coping with Methuselah, a group of practicing scientists and public policy experts come together to address the problems, challenges, and opportunities posed by a longer life span. This book will generate discussion in political, social, and medical circles and help prepare us for the extraordinary possibilities that the future may hold.

Life Extension

Author : Durk Pearson
Publisher : New York : Warner Books
ISBN 13 : 9780446879903
Total Pages : 902 pages
Book Rating : 4.8/5 (799 download)

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Book Synopsis Life Extension by : Durk Pearson

Download or read book Life Extension written by Durk Pearson and published by New York : Warner Books. This book was released on 1983 with total page 902 pages. Available in PDF, EPUB and Kindle. Book excerpt: Discusses various aspects of aging and includes suggestions on how to slow the aging process and improve your health.

Explaining Divergent Levels of Longevity in High-Income Countries

Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309217105
Total Pages : 194 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Explaining Divergent Levels of Longevity in High-Income Countries by : National Research Council

Download or read book Explaining Divergent Levels of Longevity in High-Income Countries written by National Research Council and published by National Academies Press. This book was released on 2011-06-27 with total page 194 pages. Available in PDF, EPUB and Kindle. Book excerpt: During the last 25 years, life expectancy at age 50 in the United States has been rising, but at a slower pace than in many other high-income countries, such as Japan and Australia. This difference is particularly notable given that the United States spends more on health care than any other nation. Concerned about this divergence, the National Institute on Aging asked the National Research Council to examine evidence on its possible causes. According to Explaining Divergent Levels of Longevity in High-Income Countries, the nation's history of heavy smoking is a major reason why lifespans in the United States fall short of those in many other high-income nations. Evidence suggests that current obesity levels play a substantial part as well. The book reports that lack of universal access to health care in the U.S. also has increased mortality and reduced life expectancy, though this is a less significant factor for those over age 65 because of Medicare access. For the main causes of death at older ages -- cancer and cardiovascular disease -- available indicators do not suggest that the U.S. health care system is failing to prevent deaths that would be averted elsewhere. In fact, cancer detection and survival appear to be better in the U.S. than in most other high-income nations, and survival rates following a heart attack also are favorable. Explaining Divergent Levels of Longevity in High-Income Countries identifies many gaps in research. For instance, while lung cancer deaths are a reliable marker of the damage from smoking, no clear-cut marker exists for obesity, physical inactivity, social integration, or other risks considered in this book. Moreover, evaluation of these risk factors is based on observational studies, which -- unlike randomized controlled trials -- are subject to many biases.

Life-Span Extension

Author : Christian Sell
Publisher : Springer Science & Business Media
ISBN 13 : 160327507X
Total Pages : 203 pages
Book Rating : 4.6/5 (32 download)

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Book Synopsis Life-Span Extension by : Christian Sell

Download or read book Life-Span Extension written by Christian Sell and published by Springer Science & Business Media. This book was released on 2009-07-27 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, remarkable discoveries have been made concerning the underlying mechanisms of aging. In Life-Span Extension: Single-Cell Organisms to Man, the editors bring together a range of illuminating perspectives from researchers investigating the aging process in a variety of species. This novel work addresses the aging process in species ranging from yeast to man and, among other subjects, features detailed discussions of the naked mole-rat, an exceptionally long-lived rodent; the relationship between dietary factors/food restriction and aging; and an evolutionary view of the human aging process. Single mutations that extend life span have been identified in yeast, worms, flies, and mice, whereas studies in humans have identified potentially important markers for successful aging. At the same time, it has been discovered that the genes and pathways identified in these studies involve a surprisingly small set of conserved functions, most of which have been the focus of aging research for some time. For example, the mTOR pathway, a regulator of translation and protein synthesis, has been identified as a common longevity pathway in yeast and Caenorhabditis elegans. In mammals, this pathway intersects with neuroendocrine pathways and with the insulin/insulin-like growth factor pathways, which have been identified as major modulators of life span and aging in both invertebrates and mice. Novel, emerging technologies and the increasingly wide variety of systems that are now used to study aging and the mechanisms of aging provide enormous opportunities for the identification of common pathways that modulate longevity. It is these common pathways that are the focus of this important volume.

Lifespan

Author : David A. Sinclair
Publisher : Atria Books
ISBN 13 : 1501191977
Total Pages : 432 pages
Book Rating : 4.5/5 (11 download)

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Book Synopsis Lifespan by : David A. Sinclair

Download or read book Lifespan written by David A. Sinclair and published by Atria Books. This book was released on 2019-09-10 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.” —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Exceptional Longevity

Author : Bernard Jeune
Publisher :
ISBN 13 :
Total Pages : 180 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Exceptional Longevity by : Bernard Jeune

Download or read book Exceptional Longevity written by Bernard Jeune and published by . This book was released on 1995 with total page 180 pages. Available in PDF, EPUB and Kindle. Book excerpt: States that the number of genuine long-livers is exploding and a substantial proportion of new-borns in developed countries may survive to celebrate their 100th birthday. This book examines the storied realms of exceptional longevity.

Immortality:

Author : Ben Bova
Publisher : William Morrow
ISBN 13 : 9780380975181
Total Pages : 283 pages
Book Rating : 4.9/5 (751 download)

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Book Synopsis Immortality: by : Ben Bova

Download or read book Immortality: written by Ben Bova and published by William Morrow. This book was released on 1998-09-01 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first immortals are already living among us. You might be one of them. At first glance, that arresting statement sounds as if it might come from a science fiction story. But it is an astonishing, exciting fact--as explained clearly and cogently by Dr. Ben Bova. In his distinguished career, Dr. Bova has predicted the discovery of life on Mars, the space race of the 1960s, solar-powered satellites, the discovery of organic chemicals in interstellar space, virtual reality, the Strategic Defense Initiative, the advent of international peacekeeping forces, the discovery of ice on the Moon, and electronic book publishing Now he explores the future effects of science and technology on the human life span--and discovers that one day, death will no longer be the inevitable end of life. Dr. Bova guides readers through worldwide research into the biochemical processes that cause aging and death, and shows what scientists are discovering about stopping, perhaps even reversing these processes According to Dr. Bova, if you have a normal life expectancy today, the medical and biological advances that will be achieved over the next ten to twenty years will probably allow you to live long past one hundred The longer you live, the more knowledge scientists will glean, and the further they will be able to extend your life span. With crystal-clear, utterly accessible prose Dr. Bova explains how science could maintain the youth and vigor of a fifty-year-old indefinitely, perhaps even reversing the effects of aging He also offers provocative thoughts on the tumultuous societal consequences of such biomedical breakthroughs, as greatly extended life spans and virtual immortality transform institutions like Medicare, Social Security, pension plans, life insurance, even the very foundations of work and retirement Here is a compelling, startling, understandable, and vitally important study of the greatest challenge--and the most tantalizing opportunity--ever faced by The first immortals are already living among us. You might be one of them. At first glance, that arresting statement sounds as if it might come from a science fiction story. But it is an astonishing, exciting fact--as explained clearly and cogently by Dr. Ben Bova. In his distinguished career, Dr. Bova has predicted the discovery of life on Mars, the space race of the 1960s, solar-powered satellites, the discovery of organic chemicals in interstellar space, virtual reality, the Strategic Defense Initiative, the advent of international peacekeeping forces, the discovery of ice on the Moon, and electronic book publishing Now he explores the future effects of science and technology on the human life span--and discovers that one day, death will no longer be the inevitable end of life. Dr. Bova guides readers through worldwide research into the biochemical processes that cause aging and death, and shows what scientists are discovering about stopping, perhaps even reversing these processes According to Dr. Bova, if you have a normal life expectancy today, the medical and biological advances that will be achieved over the next ten to twenty years will probably allow you to live long past one hundred The longer you live, the more knowledge scientists will glean, and the further they will be able to extend your life span. With crystal-clear, utterly accessible prose Dr. Bova explains how science could maintain the youth and vigor of a fifty-year-old indefinitely, perhaps even reversing the effects of aging He also offers provocative thoughts on the tumultuous societal consequences of such biomedical breakthroughs, as greatly extended life spans and virtual immortality transform institutions like Medicare, Social Security, pension plans, life insurance, even the very foundations of work and retirement Here is a compelling, startling, understandable, and vitally important study of the greatest challenge--and the most tantalizing opportunity--ever faced by

The Biology of Human Longevity

Author : Caleb E. Finch
Publisher : Elsevier
ISBN 13 : 9780080545943
Total Pages : 640 pages
Book Rating : 4.5/5 (459 download)

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Book Synopsis The Biology of Human Longevity by : Caleb E. Finch

Download or read book The Biology of Human Longevity written by Caleb E. Finch and published by Elsevier. This book was released on 2010-07-28 with total page 640 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by Caleb Finch, one of the leading scientists of our time, The Biology of Human Longevity: Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research on the topic of human aging and longevity particularly on the recent theories of inflammation and its effects on human health. The book expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure. This timely and topical book will be of interest to anyone studying aging from any scientific angle. Author Caleb Finch is a highly influential and respected scientist, ranked in the top half of the 1% most cited scientists Provides a novel synthesis of existing ideas about the biology of longevity and aging Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition

Ending Aging

Author : Aubrey de Grey
Publisher : Macmillan + ORM
ISBN 13 : 1429931833
Total Pages : 452 pages
Book Rating : 4.4/5 (299 download)

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Book Synopsis Ending Aging by : Aubrey de Grey

Download or read book Ending Aging written by Aubrey de Grey and published by Macmillan + ORM. This book was released on 2007-09-04 with total page 452 pages. Available in PDF, EPUB and Kindle. Book excerpt: MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Epigenetics of Aging

Author : Trygve O. Tollefsbol
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Age Later

Author : Nir Barzilai, M.D.
Publisher : St. Martin's Press
ISBN 13 : 1250230861
Total Pages : 320 pages
Book Rating : 4.2/5 (52 download)

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Book Synopsis Age Later by : Nir Barzilai, M.D.

Download or read book Age Later written by Nir Barzilai, M.D. and published by St. Martin's Press. This book was released on 2020-06-16 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

Should We Live Forever?

Author : Gilbert Meilaender
Publisher : Wm. B. Eerdmans Publishing
ISBN 13 : 1467437549
Total Pages : 136 pages
Book Rating : 4.4/5 (674 download)

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Book Synopsis Should We Live Forever? by : Gilbert Meilaender

Download or read book Should We Live Forever? written by Gilbert Meilaender and published by Wm. B. Eerdmans Publishing. This book was released on 2013-01-14 with total page 136 pages. Available in PDF, EPUB and Kindle. Book excerpt: In Should We Live Forever? Christian ethicist Gilbert Meilaender puzzles over the implications of the medical advances that have lengthened the human life span, wrestling with what this quest for living longer means for our conception of living well and completely. As he points out in his introduction, "That we often desire, even greedily desire, longer life is clear; whether what we desire is truly desirable is harder to say." The six chapters of this book take multiple perspectives on issues surrounding aging and invite readers to consider whether "indefinitely more life" is something worth pursuing and, if humans are created for life with God, whether longer life will truly satisfy our underlying hunger.

Extending the Human Life Span

Author : Bernice L. Neugarten
Publisher :
ISBN 13 :
Total Pages : 88 pages
Book Rating : 4.:/5 (43 download)

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Book Synopsis Extending the Human Life Span by : Bernice L. Neugarten

Download or read book Extending the Human Life Span written by Bernice L. Neugarten and published by . This book was released on 1977 with total page 88 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nutrition Across the Lifespan for Healthy Aging

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309457513
Total Pages : 169 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Nutrition Across the Lifespan for Healthy Aging by : National Academies of Sciences, Engineering, and Medicine

Download or read book Nutrition Across the Lifespan for Healthy Aging written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2017-05-11 with total page 169 pages. Available in PDF, EPUB and Kindle. Book excerpt: In September 2016, the National Academies of Sciences, Engineering, and Medicine convened a workshop to examine trends and patterns in aging and factors related to healthy aging in the United States, with a focus on nutrition, and how nutrition can sustain and promote healthy aging, not just in late adulthood, but beginning in pregnancy and early childhood and extending throughout the lifespan. Participants discussed the role of nutrition in the aging process at various stages in life, changes in organ systems over the lifespan and changes that occur with age related to cognitive, brain, and mental health, and explored opportunities to move forward in promoting healthy aging in the United States. This publication summarizes the presentations and discussions from the workshop.

Living with God

Author : Carlo Leget
Publisher : Peeters Publishers
ISBN 13 : 9789068319668
Total Pages : 316 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis Living with God by : Carlo Leget

Download or read book Living with God written by Carlo Leget and published by Peeters Publishers. This book was released on 1997 with total page 316 pages. Available in PDF, EPUB and Kindle. Book excerpt: What is the relation between human life on earth and 'life' after death in the theology of Saint Thomas Aquinas (1224/5-1274)? In this study this question is dealt with from the perspective of the foundations, dynamism and perfection of the human relationship with God. It is shown how Aquinas' ('negative') theological analysis of 'life' as a name of God works out in qualifying his account of both human life on earth and 'life' after death as two interrelated modes of living with God. Written at an accessible level and having the width of a thematic study on the key-word 'life', this book can also be read as an introduction to the theology of Thomas Aquinas.

New Methuselahs

Author : John K. Davis
Publisher : MIT Press
ISBN 13 : 026255156X
Total Pages : 369 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis New Methuselahs by : John K. Davis

Download or read book New Methuselahs written by John K. Davis and published by MIT Press. This book was released on 2024-03-19 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: An examination of the ethical issues raised by the possibility of human life extension, including its desirability, unequal access, and the threat of overpopulation. Life extension—slowing or halting human aging—is now being taken seriously by many scientists. Although no techniques to slow human aging yet exist, researchers have successfully slowed aging in yeast, mice, and fruit flies, and have determined that humans share aging-related genes with these species. In New Methuselahs, John Davis offers a philosophical discussion of the ethical issues raised by the possibility of human life extension. Why consider these issues now, before human life extension is a reality? Davis points out that, even today, we are making policy and funding decisions about human life extension research that have ethical implications. With New Methuselahs, he provides a comprehensive guide to these issues, offering policy recommendations and a qualified defense of life extension. After an overview of the ethics and science of life extension, Davis considers such issues as the desirability of extended life; whether refusing extended life is a form of suicide; the Malthusian threat of overpopulation; equal access to life extension; and life extension and the right against harm. In the end, Davis sides neither with those who argue that there are no moral objections to life enhancement nor with those who argue that the moral objections are so strong that we should never develop it. Davis argues that life extension is, on balance, a good thing and that we should fund life extension research aggressively, and he proposes a feasible and just policy for preventing an overpopulation crisis.