Evolving Concepts In Sepsis And Septic Shock

Download Evolving Concepts In Sepsis And Septic Shock full books in PDF, epub, and Kindle. Read online Evolving Concepts In Sepsis And Septic Shock ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Evolving Concepts in Sepsis and Septic Shock

Author : Peter Q. Eichacker
Publisher : Springer Science & Business Media
ISBN 13 : 1461515815
Total Pages : 214 pages
Book Rating : 4.4/5 (615 download)

DOWNLOAD NOW!

Book Synopsis Evolving Concepts in Sepsis and Septic Shock by : Peter Q. Eichacker

Download or read book Evolving Concepts in Sepsis and Septic Shock written by Peter Q. Eichacker and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 214 pages. Available in PDF, EPUB and Kindle. Book excerpt: Much research over the past 30 to 40 years has shown that the inflammatory response, while critical for host defense during microbial infection, may itself play a central role in the pathogenesis of sepsis. Although key mediators responsible for this injury have been identified, efforts clinically to augment our conventional antimicrobial and supportive therapies during sepsis with agents modulating the inflammatory response have been unsuccessful. As a result, the mortality associated with this lethal syndrome, especially when complicated by shock, has remained persistently high. Unfortunately, during this same period of time, the incidence of sepsis has accelerated as other fields of medicine have relied increasingly on therapies that predispose to infection. While frustrating, overall this experience in the field of sepsis has not been without value. Most importantly, it has helped define on several different levels the complexity of the septic patient. Recognizing and addressing this complexity as discussed by each of the contributors to Evolving Concepts in Sepsis and Septic Shock may now provide new inroads into the treatment of sepsis.

Hemodynamic Monitoring

Author : Michael R. Pinsky
Publisher : Springer
ISBN 13 : 3319692690
Total Pages : 476 pages
Book Rating : 4.3/5 (196 download)

DOWNLOAD NOW!

Book Synopsis Hemodynamic Monitoring by : Michael R. Pinsky

Download or read book Hemodynamic Monitoring written by Michael R. Pinsky and published by Springer. This book was released on 2019-02-21 with total page 476 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, part of the European Society of Intensive Care Medicine textbook series, teaches readers how to use hemodynamic monitoring, an essential skill for today’s intensivists. It offers a valuable guide for beginners, as well as for experienced intensivists who want to hone their skills, helping both groups detect an inadequacy of perfusion and make the right choices to achieve the main goal of hemodynamic monitoring in the critically ill, i.e., to correctly assess the cardiovascular system and its response to tissue oxygen demands. The book is divided into distinguished sections: from physiology to pathophysiology; clinical assessment and measurements; and clinical practice achievements including techniques, the basic goals in clinical practice as well as the more appropriate hemodynamic therapy to be applied in different conditions. All chapters use a learning-oriented style, with practical examples, key points and take home messages, helping readers quickly absorb the content and, at the same time, apply what they have learned in the clinical setting. The European Society of Intensive Care Medicine has developed the Lessons from the ICU series with the vision of providing focused and state-of-the-art overviews of central topics in Intensive Care and optimal resources for clinicians working in Intensive Care.

Septic Shock

Author : George H. Sakorafas
Publisher : Nova Publishers
ISBN 13 : 9781594541681
Total Pages : 128 pages
Book Rating : 4.5/5 (416 download)

DOWNLOAD NOW!

Book Synopsis Septic Shock by : George H. Sakorafas

Download or read book Septic Shock written by George H. Sakorafas and published by Nova Publishers. This book was released on 2005 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: Sepsis is one of the most frequent complications in the surgical patient and one of the leading causes of mortality in intensive care units. During the past two decades, a great deal has been learned about surgical bacteriology, antibiotic prophylaxis, supportive management, and the host response to microbial invasion. Sepsis can be caused by infection with gram-negative bacteria, gram-positive bacteria, fungi (and particularly Candida), or viruses. Sepsis may also occur in the absence of detectable bacterial invasion, and in these cases, microbial toxins, particularly gram-negative bacterial endotoxin (lipopolysaccharide, LPS), and endogenous cytokine production have been implicated as initiators and mediators. Although activation of the immune system during microbial invasion is generally protective, septic shock develops in a significant number of patients as a consequence of a poorly regulated immune response to the offending organism. Sepsis can be presented with a spectrum of severity. Septic shock represents the most severe form of host response to infection. The aim of this monograph is to summarise the currently available data regarding epidemiology, pathogenesis, and optimal management of septic shock, with a particular emphasis on the role of source control in sepsis. Emerging therapies for septic shock are also discussed.

Sepsis

Author : Nicholas S. Ward
Publisher : Humana Press
ISBN 13 : 3319484702
Total Pages : 271 pages
Book Rating : 4.3/5 (194 download)

DOWNLOAD NOW!

Book Synopsis Sepsis by : Nicholas S. Ward

Download or read book Sepsis written by Nicholas S. Ward and published by Humana Press. This book was released on 2017-05-29 with total page 271 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to provide a comprehensive and state-of-the-art resource for clinicians who care for patients with sepsis and research scientist alike, . Patients with severe sepsis requiring ICU admission have very high rates of ICU and overall hospital mortality, with estimates ranging from 18 to 50%. Risk factors for death from sepsis include underlying illness, increased age, and multi-system organ failure. This is compounded by the significant variation in the management of early severe sepsis. Care of these patients and clinical conditions can be quite complex, and materials are collected from the most current, evidence-based resources. Book sections have been structured to review the overall definitions and epidemiology of sepsis as well as current insights into the pathophysiology of sepsis. This review summarizes the evidence for the international consensus guidelines for the identification and management of sepsis. The latter part of this book reviews emerging concepts and approaches in the diagnosis and management of sepsis that may significantly reduce mortality in the future. Sepsis: Pathophysiology, Definitions and the Challenge of Bedside Management represents a collaboration between authors drawn from a variety of disciplines and contributions from basic scientists and highly recognized clinical opinion leaders with expertise in clinical trials.

Continuous Renal Replacement Therapy

Author : John A. Kellum
Publisher : Oxford University Press
ISBN 13 : 019022553X
Total Pages : 329 pages
Book Rating : 4.1/5 (92 download)

DOWNLOAD NOW!

Book Synopsis Continuous Renal Replacement Therapy by : John A. Kellum

Download or read book Continuous Renal Replacement Therapy written by John A. Kellum and published by Oxford University Press. This book was released on 2016 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuous Renal Replacement Therapy provides concise, evidence-based, bedside guidance for the management of critically ill patients with acute renal failure, offering quick reference answers to clinicians' questions about treatments and situations encountered in daily practice.

Pathophysiology of Shock, Sepsis, and Organ Failure

Author : Günther Schlag
Publisher : Springer Science & Business Media
ISBN 13 : 3642767362
Total Pages : 1180 pages
Book Rating : 4.6/5 (427 download)

DOWNLOAD NOW!

Book Synopsis Pathophysiology of Shock, Sepsis, and Organ Failure by : Günther Schlag

Download or read book Pathophysiology of Shock, Sepsis, and Organ Failure written by Günther Schlag and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 1180 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book current knowledge of the pathophysiology of shock, sepsis and multi organ failure is presented. The rapid progress which has been made and the results achieved in intensive care medicine are based on sound basic research, which is duly reflected in these chapters. Multiorgan failure is the foremost cause of postoperative and posttraumatic death and many complex mechanisms are involved. Only with a good foundation of basic research can abnormalities in the physiological, biochemical, and morphological course of shock be recognized and the necessary conclusions for treatment drawn. Therapy must proceed from profound knowledge of the multi variant physiological events in order to influence shock, sepsis and organ failure. Although numerous possibilities for therapy have arisen from pharmaceutical research in recent years, they are beyond the scope of this book and are not discussed here. To gain a better understanding of the pathophysiological events it was necessary to examine and to describe different models that simulate and reproduce these events. Here we describe the causative agents (shock) and the consequences (sepsis, organ failure) in two main sections, divided on the basis of their pathophysiology.

Sepsis Management in Resource-limited Settings

Author : Arjen M. Dondorp
Publisher : Springer
ISBN 13 : 3030031438
Total Pages : 216 pages
Book Rating : 4.0/5 (3 download)

DOWNLOAD NOW!

Book Synopsis Sepsis Management in Resource-limited Settings by : Arjen M. Dondorp

Download or read book Sepsis Management in Resource-limited Settings written by Arjen M. Dondorp and published by Springer. This book was released on 2019-02-08 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Essentials of Shock Management

Author : Gil Joon Suh
Publisher : Springer
ISBN 13 : 9811054061
Total Pages : 147 pages
Book Rating : 4.8/5 (11 download)

DOWNLOAD NOW!

Book Synopsis Essentials of Shock Management by : Gil Joon Suh

Download or read book Essentials of Shock Management written by Gil Joon Suh and published by Springer. This book was released on 2018-11-30 with total page 147 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is designed to offer the reader first-rate guidance on shock management in the real world. Comprehensive, evidence-based, and up-to-date instruction is provided on optimal care of patients with different types of shock – septic, hemorrhagic, cardiogenic, anaphylactic, and obstructive – at all stages from initial response through to ICU admission. As well as management, the coverage encompasses pathophysiology, clinical presentation, diagnosis, and emerging trends. A further key feature is the use of a scenario-based approach to present a series of cases based on real-life experiences. Here, a narrative style and Q&A form are employed to vividly convey scenarios that may be encountered in clinical practice and to elucidate decision making in complex circumstances. When readers experience difficulty in answering the questions, the earlier sections can be consulted to identify the correct response. This book will be of great value for all health care professionals. In particular, it will be very helpful for novice or inexperienced practitioners in emergency medicine, critical care medicine, and traumatology.

Oxford Textbook of Critical Care

Author : Webb
Publisher : Oxford University Press
ISBN 13 : 0198855435
Total Pages : 1961 pages
Book Rating : 4.1/5 (988 download)

DOWNLOAD NOW!

Book Synopsis Oxford Textbook of Critical Care by : Webb

Download or read book Oxford Textbook of Critical Care written by Webb and published by Oxford University Press. This book was released on 2020-01-10 with total page 1961 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in paperback, the second edition of the Oxford Textbook of Critical Care is a comprehensive multi-disciplinary text covering all aspects of adult intensive care management. Uniquely this text takes a problem-orientated approach providing a key resource for daily clinical issues in the intensive care unit. The text is organized into short topics allowing readers to rapidly access authoritative information on specific clinical problems. Each topic refers to basic physiological principles and provides up-to-date treatment advice supported by references to the most vital literature. Where international differences exist in clinical practice, authors cover alternative views. Key messages summarise each topic in order to aid quick review and decision making. Edited and written by an international group of recognized experts from many disciplines, the second edition of the Oxford Textbook of Critical Careprovides an up-to-date reference that is relevant for intensive care units and emergency departments globally. This volume is the definitive text for all health care providers, including physicians, nurses, respiratory therapists, and other allied health professionals who take care of critically ill patients.

Handbook of Sepsis

Author : W. Joost Wiersinga
Publisher : Springer
ISBN 13 : 3319735063
Total Pages : 264 pages
Book Rating : 4.3/5 (197 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Sepsis by : W. Joost Wiersinga

Download or read book Handbook of Sepsis written by W. Joost Wiersinga and published by Springer. This book was released on 2018-04-13 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.

Nephrology and Public Health Worldwide

Author : G.B. Silva Junior
Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 331806937X
Total Pages : 369 pages
Book Rating : 4.3/5 (18 download)

DOWNLOAD NOW!

Book Synopsis Nephrology and Public Health Worldwide by : G.B. Silva Junior

Download or read book Nephrology and Public Health Worldwide written by G.B. Silva Junior and published by Karger Medical and Scientific Publishers. This book was released on 2021-11-02 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nephrology is one of the fastest growing specialties in medicine. Nevertheless, kidney disease is one of the most serious unmet health needs in many countries. To provide healthcare access with the desirable equity worldwide, the nephrology community needs to discuss this public health issue and take part in decisions for elaboration of public health policies with more justice and equity. This book brings together key current public health problems that affect kidney function and illuminates them in contributions by an international group of nephrologists and general practitioners. The chapters review current knowledge and provide guidelines to manage these conditions and decrease the disease burden. At the end, developments in the digital era and their application to kidney disease treatment are synthesized, and a broader outlook on the future of nephrology is given. Ultimately, the publication aims to gather nephrology and public health expertise from researchers from all over the world, providing a broad vision of issues that must be discussed and overcome to guarantee a better treatment for patients with kidney diseases in the world today.

Mechanisms of Vascular Disease

Author : Robert Fitridge
Publisher : University of Adelaide Press
ISBN 13 : 1922064009
Total Pages : 589 pages
Book Rating : 4.9/5 (22 download)

DOWNLOAD NOW!

Book Synopsis Mechanisms of Vascular Disease by : Robert Fitridge

Download or read book Mechanisms of Vascular Disease written by Robert Fitridge and published by University of Adelaide Press. This book was released on 2011 with total page 589 pages. Available in PDF, EPUB and Kindle. Book excerpt: New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Heparanase

Author : Israel Vlodavsky
Publisher : Springer Nature
ISBN 13 : 3030345211
Total Pages : 871 pages
Book Rating : 4.0/5 (33 download)

DOWNLOAD NOW!

Book Synopsis Heparanase by : Israel Vlodavsky

Download or read book Heparanase written by Israel Vlodavsky and published by Springer Nature. This book was released on 2020-04-09 with total page 871 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by internationally recognized leaders in Heparanase biology, the book’s eight chapters offer an opportunity for scientists, clinicians and advanced students in cell biology, tumor biology and oncology to obtain a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications. Proteases and their involvement in cancer progression have been well addressed and documented; however, the emerging premise presented within this book is that Heparanase is a master regulator of aggressive cancer phenotypes and crosstalk with the tumor microenvironment. This endoglycosidase contributes to tumor-mediated remodeling of the extracellular matrix and cell surfaces, augmenting the bioavailability of pro-tumorigenic and pro-inflammatory growth factors and cytokines that are bound to Heparan sulfate. Compelling evidence ties Heparanase with all steps of tumor progression including tumor initiation, growth, angiogenesis, metastasis, and chemoresistance, supporting the notion that Heparanase is an important contributor to the poor outcome of cancer patients and a validated target for therapy. Unlike Heparanase, heparanase-2, a close homolog of Heparanase, lacks enzymatic activity, inhibits Heparanase, and regulates selected genes that promote normal differentiation and tumor suppression. Written by internationally recognized leaders in Heparanase biology, this volume presents a comprehensive understanding of Heparanase’s multifaceted activities in cancer, inflammation, diabetes and other diseases, as well as its related clinical applications to scientists, clinicians and advanced students in cell biology, tumor biology and oncology.

Essentials of Clinical Infectious Diseases, Second Edition

Author : William F. Wright, DO, MPH
Publisher : Springer Publishing Company
ISBN 13 : 0826127827
Total Pages : 450 pages
Book Rating : 4.8/5 (261 download)

DOWNLOAD NOW!

Book Synopsis Essentials of Clinical Infectious Diseases, Second Edition by : William F. Wright, DO, MPH

Download or read book Essentials of Clinical Infectious Diseases, Second Edition written by William F. Wright, DO, MPH and published by Springer Publishing Company. This book was released on 2018-04-28 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: Praise for the previous edition: “Approaches near perfection...This is an excellent introduction to infectious diseases by a group of authors who take a straightforward and bullet-point approach to thinking and talking about clinical issues...”—Doody’s Reviews Updated second edition of the concise but comprehensive handbook covering clinical infectious disease for students, residents, primary care medical providers, nurses, and PAs. Written in outline format with short, focused chapters, the book presents a systematic method for understanding basic mechanisms, establishing a diagnosis, and implementing appropriate treatment for commonly encountered problems. Essentials of Clinical Infectious Diseases, Second Edition begins with a general framework covering basics of clinical reasoning, antimicrobial agents and microbiology, and antimicrobial stewardship. Individual chapters devoted to the broad range of infectious diseases and topics are organized by body system and feature targeted presentation of pathogenesis and risk factors, microbial causes, clinical manifestations, patient work-up, diagnostic criteria, and medical, antimicrobial, and surgical management. The book also addresses important related topics including fever and neutropenia, approach to evaluating ectoparasite-related infections, infectious diseases approach to sepsis, travel medicine, and basics of infection control and hospital epidemiology. Designed for busy practitioners at any level looking to sharpen the clinical problem-solving skills required to provide the highest quality care to patients with infectious diseases. Key Features: Includes a new bonus chapter that addresses severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus disease 2019 (COVID-19) Presents core clinical infectious disease topics in concise easy-to-read format Revised and updated to reflect recent developments in the field consistent with evidence-based literature and current clinical practice guidelines 6 new chapters on lyme disease, anorectal infections, travel medicine, dental infections, antimicrobial stewardship, and clinical reasoning and statistics Focus on the approach to evaluation and management of the patient Incorporates essential antimicrobial therapy information with adult, pediatric, and OB-GYN dosing considerations

Practical Trends in Anesthesia and Intensive Care 2018

Author : Davide Chiumello
Publisher : Springer
ISBN 13 : 3319941895
Total Pages : 248 pages
Book Rating : 4.3/5 (199 download)

DOWNLOAD NOW!

Book Synopsis Practical Trends in Anesthesia and Intensive Care 2018 by : Davide Chiumello

Download or read book Practical Trends in Anesthesia and Intensive Care 2018 written by Davide Chiumello and published by Springer. This book was released on 2019-01-04 with total page 248 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers an essential guide to managing the most-debated hot topics of practical interest in anesthesia and intensive care. It reviews the state of the art in issues concerning both intensive care medicine and anesthesia, such as perioperative coagulation management, neuroaxial blockade and complications, postoperative pain management, pediatric airway management, septic shock and hemodynamic management, diagnosis and management of acute respiratory distress syndrome, and antifungal treatments for critically ill patients. Written by leading experts and including updated references, it provides a comprehensive, easy-to-follow update on anesthesia and intensive care. The book clearly explains complex topics, offering practicing clinicians valuable insights into the latest recommendations and evidence in the field while, at the same time, making it a vital resource for students new to the fields of anesthesia and intensive care.

Oxford Handbook of Critical Care Nursing

Author : Fiona Creed
Publisher : Oxford University Press
ISBN 13 : 0191059331
Total Pages : 417 pages
Book Rating : 4.1/5 (91 download)

DOWNLOAD NOW!

Book Synopsis Oxford Handbook of Critical Care Nursing by : Fiona Creed

Download or read book Oxford Handbook of Critical Care Nursing written by Fiona Creed and published by Oxford University Press. This book was released on 2016-01-28 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Focused on the practical issues of nursing care and nursing procedures, the Oxford Handbook of Critical Care Nursing has been written by nurses, for nurses Reflecting current best practice, this handbook is an easily accessible and evidence-based guide for all levels of nursing staff working in critical care environments. It provides the nurse at the bedside with the answers to day-to-day problems experienced when caring for critically ill patients, and is also a guide to some of the less commonly encountered issues. Now including more detail on the psychological issues facing critically ill patients and further information on the intricacies of receiving and transferring critically ill patients to and from critical care environments, this handbook is a concise, practical, evidence-based guide for nursing professionals caring for critically ill patients

Abdominal Sepsis

Author : Massimo Sartelli
Publisher : Springer
ISBN 13 : 3319597043
Total Pages : 404 pages
Book Rating : 4.3/5 (195 download)

DOWNLOAD NOW!

Book Synopsis Abdominal Sepsis by : Massimo Sartelli

Download or read book Abdominal Sepsis written by Massimo Sartelli and published by Springer. This book was released on 2018-03-20 with total page 404 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines in detail the topic of sepsis, with a focus on intra-abdominal sepsis. Particular attention is devoted to source control in the management of the infection, antimicrobial therapy and sepsis support, which represent the cornerstones of treating patients with this problem. The importance of a multidisciplinary approach is highlighted not only by the instructive and informative sections on the acute manifestations of appendicitis, cholecystitis, and cholangitis, perforations and diverticulitis, Clostridium difficile infection and the role of candida in abdominal sepsis, but also by an extensive discussion of issues including antimicrobial resistance, damage control surgery, principles of antimicrobial therapy, hemodynamic support, adjunctive therapies, and thromboprophylaxis. Abdominal sepsis is the host’s systemic inflammatory response to intra-abdominal infections. It is associated with significant morbidity and mortality rates, and represents the second most common cause of sepsis-related mortality at intensive care units. Gathering contributions by authoritative experts from all around the world, this book will allow acute care surgeons, abdominal surgeons, intensive care clinicians, and students to broaden their understanding of intra-abdominal sepsis in daily clinical practice.