Evaluation Of The Role Of Cell Mediated Immunity In Efficacy Of Experimental Alternative Schedule Of Live Attenuated Rb51 Vaccine Against Brucellosis In Cattle

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Evaluation of the Role of Cell-mediated Immunity in Efficacy of Experimental Alternative Schedule of Live Attenuated RB51 Vaccine Against Brucellosis in Cattle

Author : Alexandria E. Kesterson
Publisher :
ISBN 13 : 9781321905915
Total Pages : 90 pages
Book Rating : 4.9/5 (59 download)

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Book Synopsis Evaluation of the Role of Cell-mediated Immunity in Efficacy of Experimental Alternative Schedule of Live Attenuated RB51 Vaccine Against Brucellosis in Cattle by : Alexandria E. Kesterson

Download or read book Evaluation of the Role of Cell-mediated Immunity in Efficacy of Experimental Alternative Schedule of Live Attenuated RB51 Vaccine Against Brucellosis in Cattle written by Alexandria E. Kesterson and published by . This book was released on 2015 with total page 90 pages. Available in PDF, EPUB and Kindle. Book excerpt: The hypothesis of this study is that RB51 booster vaccinations will provide either increased cell mediated or humoral immunity as compared to a single calf-hood vaccination alone. This research includes four specific aims; 1) that multiple doses of RB51 vaccine will induce a measurable increase in cell-mediated and humoral immunity and that this will correlate with a decreased incidence of infection and abortion at challenge; 2) that multiple doses of RB51 will not induce abortion when an adult booster vaccination is given during pregnancy; 3) that we will be able to correlate cell-mediated immunity data with a predicted outcome at challenge to establish an immune correlate for vaccination; 4) that RB51 titers to multiple doses of vaccine will correlate with previous studies in terms of safety of the vaccine. Cattle have been divided into four treatment groups; three treatment groups (n=7 each) and a control group (n=4). Each treatment group was assigned to be vaccinated with zero, one, two, or three doses of vaccine. All cattle were treated under normal ranching conditions and were vaccinated for diseases following the usual protocols for this region. Cell-mediated immunity has been measured through semi-quantitative PCR, cytokine suspension array, flow cytometry, and cell proliferation and killing assays. Humoral immunity was measured through an RB51 ELISA developed de novo at the Wyoming State Veterinary Laboratory (WSVL). Cell killing assays were used to determine the up-regulation in cytokine expression and cell killing. An immortalized bovine macrophage cell line was obtained from the United States Department of Agriculture facility in Ames, IA to perform cell-mediated immunity assays. Baseline results will be presented for all assays listed above. The results will reflect data from all three RB51 vaccine doses. Conclusions will be presented as the characterization and comparison of all three vaccine associated immune responses. Vaccinated cattle and control cattle were challenged with B. abortus S2308 to determine the efficacy of multiple doses on bacterial burden and incidence of abortion.

Mucosal Vaccines

Author : Hiroshi Kiyono
Publisher : Academic Press
ISBN 13 :
Total Pages : 528 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Mucosal Vaccines by : Hiroshi Kiyono

Download or read book Mucosal Vaccines written by Hiroshi Kiyono and published by Academic Press. This book was released on 1996-10-14 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive, authoritative treatise covers all facets of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which with basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Key Features Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization

Brucellosis

Author : Edward J. Young
Publisher : CRC Press
ISBN 13 : 9780849366611
Total Pages : 208 pages
Book Rating : 4.3/5 (666 download)

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Book Synopsis Brucellosis by : Edward J. Young

Download or read book Brucellosis written by Edward J. Young and published by CRC Press. This book was released on 1989-05-31 with total page 208 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fourteen brucellosis experts from seven countries discuss the history, epidemiology, microbiology, immunology, diagnosis, treatment, and control of brucellosis in animals and man. Edited by members of the World Health Organization's Expert Committee on Brucellosis, this text is the first comprehensive treatment of the disease since The Nature of Brucellosis by Wesley W. Spink in 1956. Topics reviewed with current references include infection caused by newer species of Brucella, such as B. canis, newer diagnostic techniques, such as radioimmunoassay and ELISA, and newer treatments, such as rifampin and the quinolones. The pathogenesis and pathophysiology of brucellosis is reviewed in depth, correlating the disease in animals with the illness in humans. This volume is extremely useful for clinicians, researchers, and students in medicine, veterinary science, microbiology, immunology, epidemiology, public health, and international health.

Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries

Author : Yashpal Singh Malik
Publisher : Academic Press
ISBN 13 : 0128163534
Total Pages : 564 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries by : Yashpal Singh Malik

Download or read book Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries written by Yashpal Singh Malik and published by Academic Press. This book was released on 2019-09-14 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomics and Biotechnological Advances in Veterinary, Poultry, and Fisheries is a comprehensive reference for animal biotechnologists, veterinary clinicians, fishery scientists, and anyone who needs to understand the latest advances in the field of next generation sequencing and genomic editing in animals and fish. This essential reference provides information on genomics and the advanced technologies used to enhance the production and management of farm and pet animals, commercial and non-commercial birds, and aquatic animals used for food and research purposes. This resource will help the animal biotechnology research community understand the latest knowledge and trends in this field. Presents biological applications of cattle, poultry, marine and animal pathogen genomics Discusses the relevance of biomarkers to improve farm animals and fishery Includes recent approaches in cloning and transgenic cattle, poultry and fish production

Vaccines for Veterinarians E-Book

Author : Ian R Tizard
Publisher : Elsevier Health Sciences
ISBN 13 : 0323683002
Total Pages : 361 pages
Book Rating : 4.3/5 (236 download)

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Book Synopsis Vaccines for Veterinarians E-Book by : Ian R Tizard

Download or read book Vaccines for Veterinarians E-Book written by Ian R Tizard and published by Elsevier Health Sciences. This book was released on 2019-11-19 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: Both a theoretical text and a practical handbook, Vaccines for Veterinarians is the first of its kind to bring the basic science of animal vaccination and the practical details of vaccine use together in one single volume. From the first chapter on the history of vaccination and the triumph of rinderpest eradication to the last chapter on the rapidly emerging field of cancer vaccines, this book offers a truly comprehensive grounding in established and emerging vaccines for both major and minor species. Specific topics include viral vectored vaccines, DNA-plasmid vaccines, RNA vaccines, reverse vaccinology, the complexities of adjuvant use, vaccine failures and adverse events, vaccine production and regulation, robotic vaccination machines, contraceptive and production-enhancing vaccines, and so much more. At a time when resistance to human vaccination is receiving much publicity, this evidence-based book is the ideal counter to ill-informed speculation — serving as a timely reminder that vaccination is essential for the control of infectious diseases in animals. Well-respected and experienced veterinary author, Ian Tizard, provides expert guidance on the topic of vaccinations and immunology in veterinary medicine. Expert Consult site offers an online version of the book, making it easy to search the entire book electronically. The latest information on viral vectored vaccines keeps you up-to-date on the topic as well as the properties and relative advantages of currently used vectors in animal vaccines. Survey of vaccine responses covers the different mechanisms by which the immune system responds to different types of vaccines. Inclusion of the latest vaccine technologies discusses the advantages and disadvantages of DNA-plasmid vaccines, RNA vaccines, and more. Coverage of adverse events and hypersensitivities includes the best ways to treat them and report them. Coverage of passive immunization discusses the growing use of therapeutic monoclonal antibodies in veterinary medicine. Coverage of immunotherapy includes recent improvements and new products in both active and passive immunotherapy against animal cancers.

Techniques for the Brucellosis Laboratory

Author : G. G. Alton
Publisher :
ISBN 13 :
Total Pages : 216 pages
Book Rating : 4.:/5 (89 download)

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Book Synopsis Techniques for the Brucellosis Laboratory by : G. G. Alton

Download or read book Techniques for the Brucellosis Laboratory written by G. G. Alton and published by . This book was released on 1988 with total page 216 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Animal Brucellosis

Author : Klaus Nielsen
Publisher : CRC Press
ISBN 13 : 1351086588
Total Pages : 763 pages
Book Rating : 4.3/5 (51 download)

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Book Synopsis Animal Brucellosis by : Klaus Nielsen

Download or read book Animal Brucellosis written by Klaus Nielsen and published by CRC Press. This book was released on 2018-01-10 with total page 763 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely publication updates and standardizes currently used diagnostic procedures for this widespread, economically costly livestock disease. It includes state-of-the-art technology, now in limited use, which will replace the conventional methodology in the near future. The volume covers research done on improved diagnostic techniques, vaccines, taxonomy, epidemiology, pathology, and basic immunology. It is an important literature review for those more established in this field and serves as a guide to researchers or diagnosticians becoming involved with this disease.

The Buffalo (Bubalus bubalis) - Production and Research

Author : Giorgio A. Presicce
Publisher : Bentham Science Publishers
ISBN 13 : 1681084171
Total Pages : 501 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis The Buffalo (Bubalus bubalis) - Production and Research by : Giorgio A. Presicce

Download or read book The Buffalo (Bubalus bubalis) - Production and Research written by Giorgio A. Presicce and published by Bentham Science Publishers. This book was released on 2017-03-31 with total page 501 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook aims at focusing on the husbandry of the common water buffalo, (Bubalis bubalis). The book covers a broad range of topics such as the buffalo’s genetic evolution, cytogenetics, subspecies, breed diversification, feeding and metabolic specificity, adaptable response to environmental stress factors, welfare, dairy requirements and production, reproduction and embryo technologies, cryopreservation, sperm cell sexing, somatic cell cloning and transgenesis. Chapters presented and reviewed in this book have been by contributed by renowned scientists that have devoted years of research to the understanding of this species, and highlight the most recent advances in basic and applied science to unveil the understanding of physiological facets intrinsic to this animal species. The depth of the selected topics makes this book especially suited for readers of all academic levels of study. Researchers, students and professionals will find this book a useful guide to breeding and farming the water buffalo.

Observations on the Epidemical Diseases in Minorca from the Year 1744 to 1749

Author : George Cleghorn
Publisher :
ISBN 13 :
Total Pages : 352 pages
Book Rating : 4.5/5 (32 download)

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Book Synopsis Observations on the Epidemical Diseases in Minorca from the Year 1744 to 1749 by : George Cleghorn

Download or read book Observations on the Epidemical Diseases in Minorca from the Year 1744 to 1749 written by George Cleghorn and published by . This book was released on 1779 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Brucellosis of Swine

Author : Arthur Burdick Crawford
Publisher :
ISBN 13 :
Total Pages : 12 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Brucellosis of Swine by : Arthur Burdick Crawford

Download or read book Brucellosis of Swine written by Arthur Burdick Crawford and published by . This book was released on 1948 with total page 12 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Environmental Aspects of Zoonotic Diseases

Author : Robert Armon
Publisher : IWA Publishing
ISBN 13 : 184339085X
Total Pages : 517 pages
Book Rating : 4.8/5 (433 download)

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Book Synopsis Environmental Aspects of Zoonotic Diseases by : Robert Armon

Download or read book Environmental Aspects of Zoonotic Diseases written by Robert Armon and published by IWA Publishing. This book was released on 2012-01-31 with total page 517 pages. Available in PDF, EPUB and Kindle. Book excerpt: Environmental Aspects of Zoonotic Diseases provides a definitive description, commentary and research needs of environmental aspects related to zoonotic diseases. There are many interrelated connections between the environment and zoonotic diseases such as: water, soil, air and agriculture. The book presents investigations of these connections, with specific reference to environmental processes such as: deforestation, floods, draughts, irrigation practices, soil transfer and their impact on bacterial, viral, fungal, and parasitological spread. Environmental aspects such as climate (tropical, sub-tropical, temperate, arid and semi-arid), developed and undeveloped countries, animal (domestic and wild) traffic animal border crossing, commercial animal trade, transportation, as well geography and weather on zoonosis, are also discussed and relevant scientific data is condensed and organized in order to give a better picture of interrelationship between the environment and current spread of zoonotic diseases. Altogether, the book presents a remarkable and a vast amount of potential future research directions based on the link: environment-vectors-pathogens-humans. The most up-to-date source of information on this increasingly important cross-disciplinary subject, Environmental Aspects of Zoonotic Diseases will be invaluable for environmentalists, veterinarians, medical staff, environmental engineers, government agencies and consultants working in this field. Authors: Prof. Robert Armon, Technion (Israel Institute of Technology), Haifa, Israel, Dr. Uta Cheruti, Technion (Israel Institute of Technology), Haifa, Israel

Yellowstone Bison

Author : Patrick James White
Publisher :
ISBN 13 : 9780934948302
Total Pages : pages
Book Rating : 4.9/5 (483 download)

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Book Synopsis Yellowstone Bison by : Patrick James White

Download or read book Yellowstone Bison written by Patrick James White and published by . This book was released on 2015-05 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genome Mapping and Genomics in Animal-Associated Microbes

Author : Vishvanath Nene
Publisher : Springer Science & Business Media
ISBN 13 : 3540740422
Total Pages : 253 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Genome Mapping and Genomics in Animal-Associated Microbes by : Vishvanath Nene

Download or read book Genome Mapping and Genomics in Animal-Associated Microbes written by Vishvanath Nene and published by Springer Science & Business Media. This book was released on 2008-11-24 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Achievements and progress in genome mapping and the genomics of microbes supersede by far those for higher plants and animals, in part due to their enormous economic implication but also smaller genome size. In the post-genomic era, whole genome sequences of animal-associated microbes are providing clues to depicting the genetic basis of the complex host-pathogen relationships and the evolution of parasitism; and to improving methods of controlling pathogens. This volume focuses on a globally important group of intracellular prokaryotic pathogens which affect livestock animals. These include Brucella, Mycobacterium, Anaplasma and Ehrlichia, as well as the protozoan pathogens Cryptosporidium and Theileria, for which genome sequence data is available. Insights from comparative genomics of the microbes described provide clues to the adaptation involved in host-microbe interactions, as well as resources potentially useful for application in future research and product development.

The Rasputin Effect: When Commensals and Symbionts Become Parasitic

Author : Christon J. Hurst
Publisher : Springer
ISBN 13 : 3319281704
Total Pages : 364 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis The Rasputin Effect: When Commensals and Symbionts Become Parasitic by : Christon J. Hurst

Download or read book The Rasputin Effect: When Commensals and Symbionts Become Parasitic written by Christon J. Hurst and published by Springer. This book was released on 2016-07-05 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on those instances when benign and even beneficial relationships between microbes and their hosts opportunistically change and become detrimental toward the host. It examines the triggering events which can factor into these changes, such as reduction in the host’s capacity for mounting an effective defensive response due to nutritional deprivation, coinfections and seemingly subtle environmental influences like the amounts of sunlight, temperature, and either water or air quality. The effects of environmental changes can be compounded when they necessitate a physical relocation of species, in turn changing the probability of encounter between microbe and host. The change also can result when pathogens, including virus species, either have modified the opportunist or attacked the host’s protective natural microflora. The authors discuss these opportunistic interactions and assess their outcomes in both aquatic as well as terrestrial ecosystems, highlighting the impact on plant, invertebrate and vertebrate hosts.

Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3

Author : Gérald Thouand
Publisher : Springer
ISBN 13 : 3319274074
Total Pages : 202 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3 by : Gérald Thouand

Download or read book Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3 written by Gérald Thouand and published by Springer. This book was released on 2016-01-12 with total page 202 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English. /div

Bad Bug Book

Author : Mark Walderhaug
Publisher : Createspace Independent Publishing Platform
ISBN 13 : 9781495203619
Total Pages : 292 pages
Book Rating : 4.2/5 (36 download)

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Book Synopsis Bad Bug Book by : Mark Walderhaug

Download or read book Bad Bug Book written by Mark Walderhaug and published by Createspace Independent Publishing Platform. This book was released on 2014-01-14 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Bad Bug Book 2nd Edition, released in 2012, provides current information about the major known agents that cause foodborne illness.Each chapter in this book is about a pathogen—a bacterium, virus, or parasite—or a natural toxin that can contaminate food and cause illness. The book contains scientific and technical information about the major pathogens that cause these kinds of illnesses.A separate “consumer box” in each chapter provides non-technical information, in everyday language. The boxes describe plainly what can make you sick and, more important, how to prevent it.The information provided in this handbook is abbreviated and general in nature, and is intended for practical use. It is not intended to be a comprehensive scientific or clinical reference.The Bad Bug Book is published by the Center for Food Safety and Applied Nutrition (CFSAN) of the Food and Drug Administration (FDA), U.S. Department of Health and Human Services.

Microorganisms and Bioterrorism

Author : Burt Anderson
Publisher : Springer Science & Business Media
ISBN 13 : 0387281592
Total Pages : 251 pages
Book Rating : 4.3/5 (872 download)

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Book Synopsis Microorganisms and Bioterrorism by : Burt Anderson

Download or read book Microorganisms and Bioterrorism written by Burt Anderson and published by Springer Science & Business Media. This book was released on 2007-05-26 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to bring together, in a single volume, the most up-to-date information concerning microbes with potential as bioterrorist weapons. The primary audience includes microbiologists, including bacteriologists, virologists and mycologists, in academia, government laboratories and research institutes at the forefront of studies concerning microbes which have potential as bioterrorist weapons, public health physicians and researchers and scientists who must be trained to deal with bioterrorist attacks as well as laboratory investigators who must identify and characterize these microorganisms from the environment and from possibly infected patients.