Estrogen Receptor and Breast Cancer

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Author :
Publisher : Humana Press
ISBN 13 : 9783030075934
Total Pages : 432 pages
Book Rating : 4.0/5 (759 download)

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Book Synopsis Estrogen Receptor and Breast Cancer by : Xiaoting Zhang

Download or read book Estrogen Receptor and Breast Cancer written by Xiaoting Zhang and published by Humana Press. This book was released on 2019-11-08 with total page 432 pages. Available in PDF, EPUB and Kindle. Book excerpt: The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

Estrogen and Breast Cancer

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Author :
Publisher : Landes Bioscience
ISBN 13 :
Total Pages : 234 pages
Book Rating : 4.:/5 (321 download)

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Book Synopsis Estrogen and Breast Cancer by : W. R. Miller

Download or read book Estrogen and Breast Cancer written by W. R. Miller and published by Landes Bioscience. This book was released on 1996 with total page 234 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Estrogens, Estrogen Receptor and Breast Cancer

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Author :
Publisher : IOS Press
ISBN 13 : 9780967335544
Total Pages : 280 pages
Book Rating : 4.3/5 (355 download)

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Book Synopsis Estrogens, Estrogen Receptor and Breast Cancer by : Fritz F. Parl

Download or read book Estrogens, Estrogen Receptor and Breast Cancer written by Fritz F. Parl and published by IOS Press. This book was released on 2000 with total page 280 pages. Available in PDF, EPUB and Kindle. Book excerpt: Estrogens have been implicated to play a role in the development of breast cancer. The purpose of this book is to provide a comprehensive analysis of experimental, clinical and epidemiological evidence in support of the carcinogenicity of estrogens.

Adjuvant Therapy for Breast Cancer

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 0387751157
Total Pages : 483 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Adjuvant Therapy for Breast Cancer by : Monica Castiglione

Download or read book Adjuvant Therapy for Breast Cancer written by Monica Castiglione and published by Springer Science & Business Media. This book was released on 2009-07-11 with total page 483 pages. Available in PDF, EPUB and Kindle. Book excerpt: Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Hormonal Carcinogenesis V

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Publisher : Springer Science & Business Media
ISBN 13 : 0387690808
Total Pages : 647 pages
Book Rating : 4.3/5 (876 download)

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Book Synopsis Hormonal Carcinogenesis V by : Jonathan J. Li

Download or read book Hormonal Carcinogenesis V written by Jonathan J. Li and published by Springer Science & Business Media. This book was released on 2008-04-24 with total page 647 pages. Available in PDF, EPUB and Kindle. Book excerpt: Information gathered from cell-free systems, cell cultures, animal models, and human studies, together provide important insights to our understanding of hormonal cancer causation, development, and prevention; the primary objective of these Symposia. A special emphasis is placed on the two major endocrine-related cancers, that is, breast and prostate. The emerging fields of colon, lung, and pancreatic cancers in relation to hormones are examined.

Hormones and Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 9780817637972
Total Pages : 636 pages
Book Rating : 4.6/5 (379 download)

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Book Synopsis Hormones and Cancer by : Wayne Vedeckis

Download or read book Hormones and Cancer written by Wayne Vedeckis and published by Springer Science & Business Media. This book was released on 1996-04-01 with total page 636 pages. Available in PDF, EPUB and Kindle. Book excerpt: The series, Hormones in Health and Disease, was launched in 1993 to provide a scientific platform for investigators engaged in research on the biological actions of hormones and to anticipate relevance for their findings in clinical applications. The first volume of the series was dedicated to the discussion and understanding of molecular mechanisms by which steroid hormones influence target cells in normal and pathological conditions. With the diversity of information and the vast amount of literature on steroid hormone physiology, a more thorough treatment of Hormones and Cancer was identified as a timely topic. In this second volume in the series, Dr. Wayne V. Vedeckis has success fully undertaken the monumental task of editing the findings of the leading investigators in hormone and cancer research. Dr. Vedeckis brings to this project two decades of research experience in hormone action; he is actively engaged in elucidating hormone and cancer interrelations. It is a pleasure to welcome him to the series as an editor and congratulate him and all contribu tors in presenting this comprehensive treatise. The 20 chapters include discussions on contemporary topics relating control of cell division and signal transduction to the basic mechanisms of carcinogenesis by cloning patient genes, and recognizing the importance of steroid receptors in treatment protocols of various endocrine abnormalities.

Estrogen Matters

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Author :
Publisher : Hachette UK
ISBN 13 : 0316481181
Total Pages : 268 pages
Book Rating : 4.3/5 (164 download)

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Book Synopsis Estrogen Matters by : Carol Tavris

Download or read book Estrogen Matters written by Carol Tavris and published by Hachette UK. This book was released on 2018-09-04 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: A compelling defense of hormone replacement therapy, exposing the faulty science behind its fall from prominence and empowering women to make informed decisions about their health. For years, hormone replacement therapy (HRT) was hailed as a miracle. Study after study showed that HRT, if initiated at the onset of menopause, could ease symptoms ranging from hot flashes to memory loss; reduce the risk of heart disease, Alzheimer's, osteoporosis, and some cancers; and even extend a woman's overall life expectancy. But when a large study by the Women's Health Initiative announced results showing an uptick in breast cancer among women taking HRT, the winds shifted abruptly, and HRT, officially deemed a carcinogen, was abandoned. Now, sixteen years after HRT was left for dead, Dr. Bluming, a medical oncologist, and Dr. Tavris, a social psychologist, track its strange history and present a compelling case for its resurrection. They investigate what led the public -- and much of the medical establishment -- to accept the Women's Health Initiative's often exaggerated claims, while also providing a fuller picture of the science that supports HRT. A sobering and revelatory read, Estrogen Matters sets the record straight on this beneficial treatment and provides an empowering path to wellness for women everywhere.

Obesity and Cancer

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Author :
Publisher : Springer
ISBN 13 : 3319425420
Total Pages : 258 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Obesity and Cancer by : Tobias Pischon

Download or read book Obesity and Cancer written by Tobias Pischon and published by Springer. This book was released on 2016-12-01 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of the relationship between obesity and cancer. It opens with a global perspective on obesity and cancer incidence, followed by in-depth discussions of those cancers for which we have sufficient evidence of a causal relationship with obesity. It addresses topics such as the effects of obesity on cancer incidence and cancer survival, the effects of weight gain and weight loss in adulthood on cancer risk, the effects of childhood and adolescent obesity, and the role of body fat distribution in cancer risk. Individual chapters discuss potential pathways for the observed associations and explore possible mechanisms from both an epidemiological and an experimental perspective. It concludes with a population perspective on the cancer risk that is attributable to obesity and is thus potentially avoidable. This book is of particular value to researchers and epidemiologists and is also of interest to public health workers and clinicians.

Estrogen/antiestrogen Action and Breast Cancer Therapy

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Author :
Publisher : Univ of Wisconsin Press
ISBN 13 : 9780299104801
Total Pages : 564 pages
Book Rating : 4.1/5 (48 download)

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Book Synopsis Estrogen/antiestrogen Action and Breast Cancer Therapy by : Virgil Craig Jordan

Download or read book Estrogen/antiestrogen Action and Breast Cancer Therapy written by Virgil Craig Jordan and published by Univ of Wisconsin Press. This book was released on 1986 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book marks one of the achievements of the "Estrogen and Antiestrogen Action: Basic and Clinical Aspects" Wisconsin Clinical Cancer Center conference in June 1984. It is not intended to be a recount of the meeting proceedings but is, rather, a historical review of the development of this field of endeavor during the past 30 years. The chapters have been written by many of the leading experts in the field who were asked to recount the development of a particular area or laboratory idea in which they had been personally involved. The book is intended to provide both scientists and clinicians with a single-volume overview of both the basic principles of hormonal control of breast cancer and the recent clinical results from cooperative groups around the world.

Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy

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Author :
Publisher : World Health Organization
ISBN 13 : 9283212916
Total Pages : 544 pages
Book Rating : 4.2/5 (832 download)

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Book Synopsis Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy by : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Download or read book Combined Estrogen-progestogen Contraceptives and Combined Estrogen-progestogen Menopausal Therapy written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and published by World Health Organization. This book was released on 2007 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: Oral contraceptives for family planning worldwide have revolutionized the reproductive lives of millions of women since their introduction in the 1960s. Later on, a variety of side-effects including cardiovascular diseases was recognized. In response to these concerns, new generations of combined oral contraceptives were developed that featured lower dose of estrogen and newer, more potent progestogens. The effectiveness and ease of use of combined hormonal contraceptives suggest that they will continue to be used to a significant extent in the future. This ninety-first volume of IARC Monograp.

Oral Contraceptives and Breast Cancer

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Author :
Publisher : National Academies Press
ISBN 13 : 0309044936
Total Pages : 196 pages
Book Rating : 4.3/5 (9 download)

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Book Synopsis Oral Contraceptives and Breast Cancer by : Institute of Medicine

Download or read book Oral Contraceptives and Breast Cancer written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 196 pages. Available in PDF, EPUB and Kindle. Book excerpt: At least 10.7 million American women use oral contraceptives (OCs). The potential connection with breast cancer has caused concern among these OC users and uncertainty among many of their physicians. This new volume offers the most up-to-date information available on this critical topic. While the best available knowledge does not support any fundamental change in clinical practice with respect to the use of OCs, this book offers specific recommendations for more research to fully resolve the relationship between OCs and breast cancer. Noting consumer confusion, the volume includes a concise summary of benefits, risks, and other practical information for contraceptive users and their doctors. The volume presents current data on changes in patterns of OC use, differences in risk at different ages, the benefits of OCs, and more. Oral Contraceptives and Breast Cancer will be important reading for obstetricians/gynecologists and other health professionals, their patients who use OCs, contraceptive manufacturers, women's health advocates, policymakers, and researchers.

Estrogen Prevention for Breast Cancer

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Author :
Publisher :
ISBN 13 : 9781624173936
Total Pages : 168 pages
Book Rating : 4.1/5 (739 download)

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Book Synopsis Estrogen Prevention for Breast Cancer by : Zsuzsanna Suba

Download or read book Estrogen Prevention for Breast Cancer written by Zsuzsanna Suba and published by . This book was released on 2014-05-14 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: From the early 80s of the past century, clinical and epidemiological studies have increasingly pointed to an elevated breast, endometrial and ovarian cancer risk from high circulating estrogen levels. Estrogen deficiency as a cancer risk factor emerged first in 2007 in a study on Hungarian oral cancer cases based on the gender and age- related differences in tumor prevalence. Critical reevaluation of the contradictory results of hormone replacement therapy yielded a complete conversion that estrogen deficiency may confer cancer initiation. This book examines the deleterious interactions between estrogen deficiency and further hormonal disorders which illuminate the apparently controversial associations of obesity, light exposure and alcohol intake with breast cancer risk.

Cancer Prevention Research Summary

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Author :
Publisher :
ISBN 13 :
Total Pages : 56 pages
Book Rating : 4.:/5 (2 download)

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Book Synopsis Cancer Prevention Research Summary by :

Download or read book Cancer Prevention Research Summary written by and published by . This book was released on 1984 with total page 56 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Estrogen Action, Selective Estrogen Receptor Modulators, and Women's Health

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Author :
Publisher : World Scientific
ISBN 13 : 1848169582
Total Pages : 544 pages
Book Rating : 4.8/5 (481 download)

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Book Synopsis Estrogen Action, Selective Estrogen Receptor Modulators, and Women's Health by : V. Craig Jordan

Download or read book Estrogen Action, Selective Estrogen Receptor Modulators, and Women's Health written by V. Craig Jordan and published by World Scientific. This book was released on 2013 with total page 544 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume presents the evolution of the authors' ideas about estrogen action and its modulation by a new group of drugs called SERMs (Selective Estrogen Receptor Modulators). The pioneering SERMs OCo tamoxifen and raloxifene OCo are known to have saved the lives of millions of women around the world and improved the health of millions more. Estrogen is the central hormone of women's health and reproduction. The book is a journey through 40 years of discovery and success in advancing women's health, with the prospect of improved innovation through medicinal chemistry for the future.

Encyclopedia of Cancer

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Publisher : Springer Science & Business Media
ISBN 13 : 3540368477
Total Pages : 3307 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Encyclopedia of Cancer by : Manfred Schwab

Download or read book Encyclopedia of Cancer written by Manfred Schwab and published by Springer Science & Business Media. This book was released on 2008-09-23 with total page 3307 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive encyclopedic reference provides rapid access to focused information on topics of cancer research for clinicians, research scientists and advanced students. Given the overwhelming success of the first edition, which appeared in 2001, and fast development in the different fields of cancer research, it has been decided to publish a second fully revised and expanded edition. With an A-Z format of over 7,000 entries, more than 1,000 contributing authors provide a complete reference to cancer. The merging of different basic and clinical scientific disciplines towards the common goal of fighting cancer makes such a comprehensive reference source all the more timely.

What Your Doctor May Not Tell You About(TM): Breast Cancer

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Author :
Publisher : Grand Central Publishing
ISBN 13 : 0759526869
Total Pages : 383 pages
Book Rating : 4.7/5 (595 download)

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Book Synopsis What Your Doctor May Not Tell You About(TM): Breast Cancer by : John R. Lee

Download or read book What Your Doctor May Not Tell You About(TM): Breast Cancer written by John R. Lee and published by Grand Central Publishing. This book was released on 2002-01-07 with total page 383 pages. Available in PDF, EPUB and Kindle. Book excerpt: Part of the bestselling What Your Doctor May Not Tell You series, an informative, detailed guide to breast cancer, including treatment and prevention. Each year, over 40,000 women in the U.S. die from breast cancer. With statistics rising, conventional methods of treatment are simply not working, and in some cases may even be harmful. Now, Drs. Lee and Zava explain the potentially life-saving facts, such as: likely sources for the increase in breast cancer, including environment, excessive estrogen, progesterone imbalance, diet, and the dangers associated with traditional hormone replacement methods. Readers will learn strategies for lowering their risk and preventing this devastating disease through a revolutionary hormone balance program.

Estrogen's Storm Season

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Author :
Publisher : CeMCOR (Centre for Menstrual Cycle and Ovulation Research)
ISBN 13 : 0973827521
Total Pages : pages
Book Rating : 4.9/5 (738 download)

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Book Synopsis Estrogen's Storm Season by : Jerilynn C. Prior

Download or read book Estrogen's Storm Season written by Jerilynn C. Prior and published by CeMCOR (Centre for Menstrual Cycle and Ovulation Research). This book was released on 2017 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: "This fiction book begins as eight frustrated midlife women-from all walks of life-meet Dr. Kailey Madrona, a woman specialist. All are in perimenopause, the long and chaotic transition to menopause. They are as different as women can be-yet they share the mysterious experiences of perimenopause, night sweats, flooding periods or mood swings. We follow these women as they consult Dr. Madrona, learn the surprising hormonal changes explaining their symptoms, get better or worse, and try or refuse therapies. As each woman lives through her particular challenge, we begin to see how we, too, can survive perimenopause! Dr. Jerilynn Prior tells the story of women in perimenopause through a unique blend of storytelling and scientific fact."--