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Author : Elin Swedenborg
Publisher :
ISBN 13 : 9789174095296
Total Pages : 41 pages
Book Rating : 4.0/5 (952 download)
Download or read book Estrogen and Aryl Hydrocarbon Receptor Signaling written by Elin Swedenborg and published by . This book was released on 2009 with total page 41 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Weili Wang
Publisher :
ISBN 13 :
Total Pages : 378 pages
Book Rating : 4.:/5 (48 download)
Download or read book Crosstalk Between the Aryl Hydrocarbon and Estrogen Receptor Signaling Pathways in Human Breast Cancer Cells written by Weili Wang and published by . This book was released on 1998 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mona Sethi Gupta
Publisher :
ISBN 13 :
Total Pages : 394 pages
Book Rating : 4.:/5 (459 download)
Download or read book Mechanistic Studies of Xenobiotic and Natural Compounds that Modulate Estrogen-receptor and Aryl-hydrocarbon Receptor Signaling Pathways written by Mona Sethi Gupta and published by . This book was released on 2000 with total page 394 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Raymond Ho Fai Lo
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (13 download)
Download or read book Activation of Estrogen Receptor Alpha, Aryl Hydrocarbon Receptor, and Nuclear Factor Erythroid-2 Like 2 in Human Breast Cancer Cells written by Raymond Ho Fai Lo and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Neal A. Englert
Publisher :
ISBN 13 :
Total Pages : 279 pages
Book Rating : 4.:/5 (795 download)
Download or read book Regulation of the Aryl Hydrocarbon Receptor and the Signal Transducer and Activator of Transcription 1 by Long-term Estrogen Exposure in Breast Carcinoma Cells written by Neal A. Englert and published by . This book was released on 2011 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jeong Eun Lee
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (796 download)
Download or read book Mechanisms of Aryl Hydrocarbon Receptor and Estrogen Receptor Action in Breast Cancer Cells written by Jeong Eun Lee and published by . This book was released on 2006 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: In MCF7 and T47D cells cotreated with 1 nM 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) plus 0.1-10 uM 3̕,4̕ -dimethoxy flavone (DMF), there was a concentration-dependent decrease in the TCDD-induced ethoxyresorufin O-deethylase (EROD) activity. Gel mobility shift assays showed that 3̕,4̕ -DMF inhibited TCDD-induced aryl hydrocarbon receptor (AhR) transformation in rat liver cytosol and blocked TCDD-induced formation of the nuclear AhR complex in MCF7 and T47D cells. The antiestrogenic activity of TCDD in estrogen-induced transactivation assays in MCF7 cells was reversed by 3̕,4̕ -DMF, confirming the AhR antagonist activity of this compound in breast cancer cells. Cotreatment of T47D and MCF7 cells with TCDD and 10 uM resveratrol inhibited induction of CYP1A1 mRNA and EROD activity. Resveratrol did not inhibit TCDD-induced AhR transformation and reporter gene activity. Actinomycin D chase experiments in T47D cells showed that the mechanism of inhibition of CYP1A1 mRNA and EROD activity is due to an increased rate of CYP1A1 mRNA degradation, suggesting that resveratrol inhibits CYP1A1 via an AhR-independent post-transcriptional pathway. Vitamin D receptor-interacting protein 150 (DRIP150) coactivated estrogen receptor [alpha] (ER [alpha])-mediated transactivation and the response was AF2-dependent in ZR75 breast cancer cells. C-and N-terminal NR-boxes (amino acids 1186-1182 and 73-69, respectively) were not necessary for coactivation of ER [alpha]. Analysis of DRIP150 deletion mutants identified a 23 amino acid sequence (811-789) required for coactivation. The 23 amino acid contained two regions at amino acids 789-794 and 795-804 which resembled [alpha] -helical motifs identified in Lanuguinosa lipase/histamine N-methyl transferase and hepatocyte nuclear factor 1, respectively. A squelching assay using specific point mutations within each [alpha] -helix showed that the NIFSEVRVYN (795-804) region was the critical sequence required for the coactivator activity of DRIP150.
Download or read book Estrogen Receptor-α and Aryl Hydrocarbon Receptor Involvement in the Actions of Botanical Estrogens in Target Cells written by and published by . This book was released on 2016 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Rohit Singhal
Publisher :
ISBN 13 :
Total Pages : 368 pages
Book Rating : 4.:/5 (319 download)
Download or read book Modulation of Aryl Hydrocarbon Receptor Mediated Signaling by Soy Consumption and Estrogens written by Rohit Singhal and published by . This book was released on 2008 with total page 368 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : National Research Council
Publisher : National Academies Press
ISBN 13 : 0309064198
Total Pages : 453 pages
Book Rating : 4.3/5 (9 download)
Download or read book Hormonally Active Agents in the Environment written by National Research Council and published by National Academies Press. This book was released on 2000-02-03 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Author : Janina Helle
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (993 download)
Download or read book Activation of Estrogen Receptor and Aryl-hydrocarbon Receptor Pathways by Xenobiotics-consequences for Mammary Gland Biology written by Janina Helle and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book The Aryl Hydrocarbon Receptor Signaling Pathway and Adverse Reproductive Outcomes written by and published by . This book was released on 2013 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Mark Paul Labrecque
Publisher :
ISBN 13 :
Total Pages : 217 pages
Book Rating : 4.:/5 (111 download)
Download or read book The Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT) Transcriptional Co-regulator Complex written by Mark Paul Labrecque and published by . This book was released on 2016 with total page 217 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Jose Russo
Publisher : Springer
ISBN 13 : 3319271350
Total Pages : 296 pages
Book Rating : 4.3/5 (192 download)
Download or read book Trends in Breast Cancer Prevention written by Jose Russo and published by Springer. This book was released on 2016-07-14 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume, with contributions from the most recognized experts in preventive strategies in breast cancer, presents the accepted as well as the novel ideas that have been introduced for the prevention of breast cancer. There is no single preventive agent that can stop the incidence of breast cancer—the malignant disease most frequently diagnosed in women of all races and nationalities. Furthermore, its incidence around the globe is increasing in industrialized countries. The worldwide incidence of breast cancer has increased 30-40% since the 1970s, reaching an excess of 1,390,000 new cases and a mortality of more than 460,000 cases in 2015. Therefore, what is needed is the development of rational strategies for the prevention of this fatal disease.
Author : Shaimaa Ahmed
Publisher :
ISBN 13 : 9780494930779
Total Pages : pages
Book Rating : 4.9/5 (37 download)
Download or read book Molecular Mechanisms of Aryl Hydrocarbon Receptor Transactivation and Crosstalk with Estrogen Receptor Alpha written by Shaimaa Ahmed and published by . This book was released on 2012 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Murray D. Meek
Publisher :
ISBN 13 :
Total Pages : 174 pages
Book Rating : 4.:/5 (17 download)
Download or read book Role of the Estrogen Receptor and Aryl Hydrocarbon Receptor in Mediating the Estrogenic Effects of Phthalate Esters and Xenoestrogens in Cigarette Smoke and Diesel Exhaust written by Murray D. Meek and published by . This book was released on 1998 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Kary Ellen Thompson
Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (139 download)
Download or read book Involvement of the Estrogen Receptor and Aryl Hydrocarbon Receptor in 4 - Vinylcyclohexene Diepoxide- Induced Ovotoxicity in F344 Rats (PHD). written by Kary Ellen Thompson and published by . This book was released on 2001 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Role of the Estrogen Receptor and Aryl Hydrocarbon Receptor in Mediating the Estrogenic Effects of Phthalate Esters and Xenoestrogens in Cigarette Smoke and Diesel Exhaust written by and published by . This book was released on 1999 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
