Epigenetics Energy Balance And Cancer

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Epigenetics, Energy Balance, and Cancer

Author : Nathan A. Berger
Publisher : Springer
ISBN 13 : 3319416103
Total Pages : 278 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Epigenetics, Energy Balance, and Cancer by : Nathan A. Berger

Download or read book Epigenetics, Energy Balance, and Cancer written by Nathan A. Berger and published by Springer. This book was released on 2016-09-23 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of Energy Balance and Cancer provides state-of-the-art descriptions of the rapidly evolving science of epigenetics and how it may explain mechanisms by which alterations in energy balance such as obesity and physical activity may impact cancer. In addition to chapters explaining the processes mediating epigenetic regulation, the volume contains a series of chapters explaining how environmental influences including early life events, nutrition, exercise and microbiota may induce epigenetic changes that can affect carcinogenesis. The following chapters describe epigenetic relations of energy balance to cancer in distinct organ systems including esophagus, colon, prostate and breast. Epigenetics, Energy Balance and Cancer provides a valuable resource for students, research investigators and clinicians seeking to better understand these processes as well as a basis for novel translational and transdisciplinary approaches to further elucidate these processes and develop preventive and therapeutic strategies.

Introduction to Epigenetics

Author : Renato Paro
Publisher : Springer Nature
ISBN 13 : 3030686701
Total Pages : 215 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Introduction to Epigenetics by : Renato Paro

Download or read book Introduction to Epigenetics written by Renato Paro and published by Springer Nature. This book was released on 2021-03-23 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease

Impact of Energy Balance on Cancer Disparities

Author : Deborah J. Bowen
Publisher :
ISBN 13 : 9783319061047
Total Pages : 324 pages
Book Rating : 4.0/5 (61 download)

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Book Synopsis Impact of Energy Balance on Cancer Disparities by : Deborah J. Bowen

Download or read book Impact of Energy Balance on Cancer Disparities written by Deborah J. Bowen and published by . This book was released on 2014-08-31 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Energy Balance and Cancer

Author :
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (731 download)

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Book Synopsis Energy Balance and Cancer by :

Download or read book Energy Balance and Cancer written by and published by . This book was released on 2010 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Nutrition, Diet, and Epigenetics

Author : Vinood B. Patel
Publisher : Springer
ISBN 13 : 9783319555294
Total Pages : 0 pages
Book Rating : 4.5/5 (552 download)

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Book Synopsis Handbook of Nutrition, Diet, and Epigenetics by : Vinood B. Patel

Download or read book Handbook of Nutrition, Diet, and Epigenetics written by Vinood B. Patel and published by Springer. This book was released on 2019-02-27 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This multivolume reference work addresses the fact that the well being of humankind is predicated not only on individuals receiving adequate nutrition but also on their genetic makeup. The work includes more than 100 chapters organized in the following major sections: Introduction and Overview; Epigenetics of Organs and Diseases in Relation to Diet and Nutrition; Detailed Processes in Epigenetics of Diet and Nutrition; Modulating Epigenetics with Diet and Nutrition; and Practical Techniques. While it is well known that genes may encode proteins responsible for structural and dynamic components, there is an increasing body of evidence to suggest that nutrition itself may alter the way in which genes are expressed via the process of epigenetics. This is where chemically imposed alteration in the DNA sequence occurs or where the functional expression of DNA is modulated. This may include changes in DNA methylation, non-coding RNA, chromatin, histone acetylation or methylation, and genomic imprinting. Knowledge regarding the number of dietary components that impact on epigenetic processes is increasing almost daily. Marshalling all the information on the complex relationships between diet, nutrition, and epigenetic processes is somewhat difficult due to the wide myriad of material. It is for this reason that the present work has been compiled.

Physical Activity and Cancer

Author : Kerry S. Courneya
Publisher : Springer Science & Business Media
ISBN 13 : 3642042317
Total Pages : 389 pages
Book Rating : 4.6/5 (42 download)

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Book Synopsis Physical Activity and Cancer by : Kerry S. Courneya

Download or read book Physical Activity and Cancer written by Kerry S. Courneya and published by Springer Science & Business Media. This book was released on 2010-11-26 with total page 389 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores in depth the relation between physical activity and cancer control, including primary prevention, coping with treatments, recovery after treatments, long-term survivorship, secondary prevention, and survival. The first part of the book presents the most recent research on the impact of physical activity in preventing a range of cancers. In the second part, the association between physical activity and cancer survivorship is addressed. The effects of physical activity on supportive care endpoints (e.g., quality of life, fatigue, physical functioning) and disease endpoints (e.g., biomarkers, recurrence, survival) are carefully analyzed. In addition, the determinants of physical activity in cancer survivors are discussed, and behavior change strategies for increasing physical activity in cancer survivors are appraised. The final part of the book is devoted to special topics, including the relation of physical activity to pediatric cancer survivorship and to palliative cancer care.

Murine Models, Energy Balance, and Cancer

Author : Nathan A. Berger
Publisher : Springer
ISBN 13 : 3319167332
Total Pages : 302 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Murine Models, Energy Balance, and Cancer by : Nathan A. Berger

Download or read book Murine Models, Energy Balance, and Cancer written by Nathan A. Berger and published by Springer. This book was released on 2015-06-19 with total page 302 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides a transdisciplinary and translational review of many of the leading murine models used to study the mechanisms, mediators and biomarkers linking energy balance to cancer. It provides a review of murine models that should be of interest to basic, clinical and applied research investigators as well as nutrition scientists and students that work in cancer prevention, cancer control and treatment. The worldwide obesity pandemic has been extensively studied by epidemiologic and observational studies and even, in some cases, by randomized controlled trials. However, the development and control of obesity, its comorbidities and its impact on cancer usually occurs over such long periods that it is difficult, if not impossible to conduct randomized controlled trials in humans to investigate environmental contributions to obesity, energy balance and their impact on cancer. In contrast, model organisms, especially mice and rats, provide valuable assets for performing these studies under rigorously controlled conditions and in sufficient numbers to provide statistically significant results. In this volume, many of the leading and new murine models used to study the mechanisms and mediators linking cancer with obesity, sleep, exercise, their modification by environment and how they may continue to be used to further elucidate these relations as well as to explore preclinical aspects of prevention and/or therapeutic intervention are considered. This volume provides an important compilation and analysis of major experimental systems and principles for further preclinical research with translational impact on energy balance and cancer.

Environmental Epigenetics

Author : L. Joseph Su
Publisher : Springer
ISBN 13 : 1447166787
Total Pages : 327 pages
Book Rating : 4.4/5 (471 download)

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Book Synopsis Environmental Epigenetics by : L. Joseph Su

Download or read book Environmental Epigenetics written by L. Joseph Su and published by Springer. This book was released on 2015-05-18 with total page 327 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Energy Balance and Obesity

Author : Isabelle Romieu
Publisher : IARC Working Group Report
ISBN 13 : 9789283225195
Total Pages : 0 pages
Book Rating : 4.2/5 (251 download)

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Book Synopsis Energy Balance and Obesity by : Isabelle Romieu

Download or read book Energy Balance and Obesity written by Isabelle Romieu and published by IARC Working Group Report. This book was released on 2018-01-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Understanding the relationship between energy balance and obesity is essential to develop effective prevention programs and policies. The International Agency for Research on Cancer convened a Working Group of world-leading experts in December 2015 to review the evidence regarding energy balance and obesity, with a focus on low- and middle-income countries, and to consider the following scientific questions: (i) Are the drivers of the obesity epidemic related only to energy excess and/or do specific foods or nutrients play a major role in this epidemic? (ii) What are the factors that modulate these associations? (iii) Which types of data and/or studies will further improve our understanding? This book provides summaries of the evidence from the literature as well as the Working Group's conclusions and recommendations to tackle the global epidemic of obesity.

Epigenetic Cancer Therapy

Author : Steven Gray
Publisher : Academic Press
ISBN 13 : 0128002247
Total Pages : 748 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Epigenetic Cancer Therapy by : Steven Gray

Download or read book Epigenetic Cancer Therapy written by Steven Gray and published by Academic Press. This book was released on 2015-07-01 with total page 748 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver). The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer. - Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlas - Discusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applications - Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs

Advances in Nutrition and Cancer 2

Author : Vincenzo Zappia
Publisher : Springer Science & Business Media
ISBN 13 : 1475732309
Total Pages : 313 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Advances in Nutrition and Cancer 2 by : Vincenzo Zappia

Download or read book Advances in Nutrition and Cancer 2 written by Vincenzo Zappia and published by Springer Science & Business Media. This book was released on 2013-03-09 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume includes contributions presented at the Second International Sym posium on Nutrition and Cancer, held in Naples, Italy, in October 1998 at the National Tumor Institute "Fondazione Pascale." During the Conference, experts from different disciplines discussed pivotal and timely subjects on the interactions between human nutrition and the development of malignancies. Comparing the themes of this Meeting with those discussed at the First Sympo sium in 1992, the major scientific advancements certainly derive from the extensive use of molecular approaches to perform research in nutrition. Moreover, the fundamental observation of R. Doll and R. Peto (1981), which suggested that at least 35% of all cancers (with large differences among different tumors) might be prevented by dietary regimens, has been definitively confirmed by epidemiological studies. On the other hand, the relationships between diet and cancer are quite intricate and complex; it is difficult, and at the same time not methodologically correct, to reduce them to simple terms. Metabolic and hormonal factors, contaminants and biological agents, and deficiency of specific protective nutrients are all pieces of the same puzzle.

Food, Nutrition, Physical Activity and the Prevention of Cancer

Author :
Publisher :
ISBN 13 :
Total Pages : 537 pages
Book Rating : 4.:/5 (476 download)

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Book Synopsis Food, Nutrition, Physical Activity and the Prevention of Cancer by :

Download or read book Food, Nutrition, Physical Activity and the Prevention of Cancer written by and published by . This book was released on 2007 with total page 537 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Genetics and Epigenetics of RNA Methylation System in Human Cancers

Author : Shicheng Guo
Publisher : Frontiers Media SA
ISBN 13 : 2889714470
Total Pages : 244 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Genetics and Epigenetics of RNA Methylation System in Human Cancers by : Shicheng Guo

Download or read book Genetics and Epigenetics of RNA Methylation System in Human Cancers written by Shicheng Guo and published by Frontiers Media SA. This book was released on 2022-02-17 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Epigenetics of Aging

Author : Trygve O. Tollefsbol
Publisher : Springer Science & Business Media
ISBN 13 : 1441906398
Total Pages : 462 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetics of Aging by : Trygve O. Tollefsbol

Download or read book Epigenetics of Aging written by Trygve O. Tollefsbol and published by Springer Science & Business Media. This book was released on 2009-11-11 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent studies have indicated that epigenetic processes may play a major role in both cellular and organismal aging. These epigenetic processes include not only DNA methylation and histone modifications, but also extend to many other epigenetic mediators such as the polycomb group proteins, chromosomal position effects, and noncoding RNA. The topics of this book range from fundamental changes in DNA methylation in aging to the most recent research on intervention into epigenetic modifications to modulate the aging process. The major topics of epigenetics and aging covered in this book are: 1) DNA methylation and histone modifications in aging; 2) Other epigenetic processes and aging; 3) Impact of epigenetics on aging; 4) Epigenetics of age-related diseases; 5) Epigenetic interventions and aging: and 6) Future directions in epigenetic aging research. The most studied of epigenetic processes, DNA methylation, has been associated with cellular aging and aging of organisms for many years. It is now apparent that both global and gene-specific alterations occur not only in DNA methylation during aging, but also in several histone alterations. Many epigenetic alterations can have an impact on aging processes such as stem cell aging, control of telomerase, modifications of telomeres, and epigenetic drift can impact the aging process as evident in the recent studies of aging monozygotic twins. Numerous age-related diseases are affected by epigenetic mechanisms. For example, recent studies have shown that DNA methylation is altered in Alzheimer’s disease and autoimmunity. Other prevalent diseases that have been associated with age-related epigenetic changes include cancer and diabetes. Paternal age and epigenetic changes appear to have an effect on schizophrenia and epigenetic silencing has been associated with several of the progeroid syndromes of premature aging. Moreover, the impact of dietary or drug intervention into epigenetic processes as they affect normal aging or age-related diseases is becoming increasingly feasible.

Epigenetics of Exercise and Sports

Author : Stuart Raleigh
Publisher : Academic Press
ISBN 13 : 0128209372
Total Pages : 320 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Epigenetics of Exercise and Sports by : Stuart Raleigh

Download or read book Epigenetics of Exercise and Sports written by Stuart Raleigh and published by Academic Press. This book was released on 2021-07-13 with total page 320 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research. Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics Includes preliminary information on exercise epigenetics and covid-19 infection Features chapter contributions from international experts in the field

Epigenetic Alterations in Oncogenesis

Author : Adam R. Karpf
Publisher : Springer Science & Business Media
ISBN 13 : 1441999671
Total Pages : 355 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Epigenetic Alterations in Oncogenesis by : Adam R. Karpf

Download or read book Epigenetic Alterations in Oncogenesis written by Adam R. Karpf and published by Springer Science & Business Media. This book was released on 2012-09-06 with total page 355 pages. Available in PDF, EPUB and Kindle. Book excerpt: The purpose of this book is to provide an up to date review of the nature and consequences of epigenetic changes in cancer. Epigenetics literally means “above” genetics, and consists of heritable gene expression or other phenotypic states not accounted for by DNA base sequence. Epigenetic changes are now known to make a large contribution to various aspects of tumorigenesis. These changes include alterations in global and promoter specific DNA methylation, activating and repressive histone modifications, and changes in higher order chromatin structures. Each of these topics will be covered in this book.

Epigenetics and Public Policy

Author : Shea K. Robison
Publisher : Bloomsbury Publishing USA
ISBN 13 : 1440844704
Total Pages : 378 pages
Book Rating : 4.4/5 (48 download)

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Book Synopsis Epigenetics and Public Policy by : Shea K. Robison

Download or read book Epigenetics and Public Policy written by Shea K. Robison and published by Bloomsbury Publishing USA. This book was released on 2018-04-19 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt: The exciting field of epigenetics offers novel and unanticipated science-based insights into human origins and development. This book presents one of the first detailed examinations of the political implications of epigenetics. Epigenetics—the study of internal and environmental factors that affect how genes are turned on or off and how cells read those genes—is a rapidly emerging science akin to genetics that introduces a number of novel and unexpected biological explanations of human origins and development. It also poses fundamental challenges to many of the assumptions of the prevailing science of genetics. When science changes, how does public policy respond? This book comprehensively considers the political implications of the emerging science of epigenetics in specific policy domains, addressing the intersections of epigenetics with cancer, obesity, the environment, and the law. Author Shea K. Robison carefully navigates the messy history of genetics and epigenetics in order to explore what changes in public policy might come in the age of a new scientific frontier. Readers will understand how new findings in epigenetic research and increased acceptance of epigenetic science may lead to paradigm shifts in cancer prevention and treatment, significantly different policy solutions for combating obesity, and revised statutes of limitations and laws regarding civil and corporate liability and wrongful life.