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End Stage Therapy And Heart Transplantation
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Book Synopsis End Stage Therapy and Heart Transplantation by :
Download or read book End Stage Therapy and Heart Transplantation written by and published by BoD – Books on Demand. This book was released on 2024-04-18 with total page 150 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the last two decades, there has been steady progress in therapeutic strategies for end-stage heart failure, such as advanced heart failure medical therapy and mechanical circulatory support before and after heart transplantation, as well as heart transplantation. This book provides a comprehensive overview of these advancements. It includes eight chapters that address topics such as cardiac reshaping nets, extracorporeal membrane oxygenation (ECMO), left ventricular assist devices (LVADs), heart transplantation in the Middle East and Japan, and more.
Book Synopsis Clinical Guide to Heart Transplantation by : Jon Kobashigawa
Download or read book Clinical Guide to Heart Transplantation written by Jon Kobashigawa and published by Springer. This book was released on 2017-03-29 with total page 258 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, with a prevalence of over 5.8 million in the USA, and over 23 million worldwide, and rising. The lifetime risk of developing heart failure is one in five. Heart failure carries substantial morbidity and mortality, with 5-year mortality that rival those of many cancers. As heart transplantation remains the best treatment option for patients with end stage heart failure, this primer will provide valuable information and management strategies for physicians caring for these patients. Also, due to continued shortage in donor organs, heart transplantation is a limited resource – which further underscores the importance of appropriately evaluating patients for transplant candidacy and managing their pre, peri- and post-transplant care for maximum benefit and best outcomes.
Book Synopsis Mechanical Circulatory Support in End-Stage Heart Failure by : Andrea Montalto
Download or read book Mechanical Circulatory Support in End-Stage Heart Failure written by Andrea Montalto and published by Springer. This book was released on 2017-07-14 with total page 615 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is a detailed practical guide to the use of ventricular assist devices and total artificial hearts to provide mechanical circulatory support (MCS) in patients with end-stage heart failure. It explains why MCS may be indicated, which patients require MCS, when and how to implant ventricular assist devices or a total artificial heart, and how to avoid potential complications of MCS. Management throughout the period of care is described, from preimplantation to follow-up, and both typical and atypical cases are discussed. The text features numerous helpful tips and tricks relating to surgical and nonsurgical management and is supported by a wealth of high-quality illustrations that document the preoperative evaluation and implantation techniques. Heart transplantation remains the gold standard for the treatment of patients suffering from end-stage heart failure, but the shortage of donors has led to an increase in the use of MCS. This book will assist all physicians, and especially cardiologists and anesthesiologists, who are involved in the care of these patients.
Book Synopsis The Artificial Heart by : Institute of Medicine
Download or read book The Artificial Heart written by Institute of Medicine and published by National Academies Press. This book was released on 1991-02-01 with total page 313 pages. Available in PDF, EPUB and Kindle. Book excerpt: A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program-and in particular, the National Institutes of Health's major investment-raising important questions. The volume includes: Consideration of the artificial heart versus heart transplantation and other approaches to treating end-stage heart disease, keeping in mind the different outcomes and costs of these treatments. A look at human issues, including the number of people who may require the artificial heart, patient quality of life, and other ethical and societal questions. Examination of how this technology's use can be targeted most appropriately. Attention to achieving access to this technology for all those who can benefit from it. The committee also offers three mechanisms to aid in allocating research and development funds.
Book Synopsis Cardiac Allograft Rejection by : G. William Dec
Download or read book Cardiac Allograft Rejection written by G. William Dec and published by Springer Science & Business Media. This book was released on 2001-09-30 with total page 464 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart transplantation remains one of the major scientific achievements of twentieth century medicine. During the past four decades, it has evolved from an unproven experimental surgical technique to the most effective form of therapy for refractory end-stage heart disease. It has captured the public's imagination and expanded our understanding of fundamental immunologic mechanisms that are responsible for cellular and humorally-mediated immunity. Despite its successes, many clinical and scientific problems remain. One or more bouts of acute cellular or humoral (vascular) rejection will occur in over 75% of transplant recipients despite current immunosuppressive strategies. Further, rejection directly results in approximately 20% of post-transplant deaths and is believed to play a major role in the development of late allograft dysfunction and coronary vasculopathy. This book by international experts in the fields of transplantation medicine, immunobiology and cardiac imaging provides the reader with an up-to-date, consise summary of the latest developments in the diagnosis and treatment of acute cardiac rejection. It is axiomatic that a more complete understanding of the pathogenic processes involved in rejection will ultimately lead to its prevention. This volume will be useful to transplant cardiologists, cardiovascular surgeons, cardiac pathologists and transplant scientists who seek to prolong the lifespan and improve the quality of life of their transplant recipients.
Book Synopsis Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease, 2 Volume Set by : Yaron D. Barac
Download or read book Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease, 2 Volume Set written by Yaron D. Barac and published by John Wiley & Sons. This book was released on 2023-09-05 with total page 2642 pages. Available in PDF, EPUB and Kindle. Book excerpt: Textbook of Transplantation and Mechanical Support for End-Stage Heart and Lung Disease Comprehensive textbook covering all aspects of the care of patients with advanced heart or lung disease Transplantation and Mechanical Support for End-Stage Heart and Lung Disease is the most comprehensive and contemporary textbook available that addresses the medical and surgical treatment options for patients with end-stage heart and lung disease. All facets of these complex and resource-intensive therapies are covered by leading experts — including the basics of transplant immunology, databases, regulatory and ethical aspects of transplantation and conventional and new modalities of donor organ harvest. Transplantation and Mechanical Support for End-Stage Heart and Lung Disease includes further information on topics such as: Historical developments that facilitated heart and lung transplantation; engineering advances in continuous flow technologies Transplant organizations, oversight, structure, process, databases and registries in the thoracic transplants and MCS field Current strategies in immune modulation, desensitization protocols and mechanisms of allograft rejection and tolerance/immunosenescence Detailed descriptions of donor and recipient surgical procedures as well as comprehensive implantation techniques for all available short- and long-term mechanical circulatory support devices, including ECMO Organ allocation and prioritization, donor evaluation, high risk donors, marginal donors, and risk assessment Richly enhanced with summary tables and color illustrations to provide an engaging and supportive learning experience, the book will serve as a highly valuable source of contemporary knowledge for medical students, residents, nurses, perfusionists, physicians and surgeons involved in the care of these desperately ill group of patients. “This comprehensive book covers all aspects of advanced heart and lung failure treatment, including shock, short-term and durable mechanical assistance, as well as transplantation. The in-depth information will be welcome by newcomers in the field as well as seasoned veterans.” —Andreas Zuckermann, M.D Vice-Chair, Department of Cardiac Surgery, Director of Cardiac Transplantation Program, Medical University of Vienna, Vienna General Hospital “This comprehensive tour-de-force compendium covers practical issues of clinical administration, program development, care pathways, ongoing challenges and opportunities in each treatment area as a must go-to reference for guidance in the rapidly evolving fields of mechanical circulatory support and transplantation.” —Mandeep R. Mehra, MBBS, MSc, FRCP Executive Director, Center for Advanced Heart Disease, Brigham and Women’s Hospital, Harvard Medical School “This unique textbook authored by key opinion leaders is a refreshing ???wind of change??? in our field, one that will well serve all professionals involved in the care of end-stage heart and lung patients for many years to come.” —Marcelo Cypel MD, MSc, FACS, FRCSC Surgical Director Ajmera Transplant Centre at UHN , University of Toronto
Book Synopsis Use of Left Ventricular Assist Devices as Destination Therapy in End-stage Congestive Heart Failure by : Thomas S. Rector
Download or read book Use of Left Ventricular Assist Devices as Destination Therapy in End-stage Congestive Heart Failure written by Thomas S. Rector and published by . This book was released on 2012 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Heart failure is defined as reduced ability of the heart to pump blood and maintain normal bodily function. Heart transplantation is currently the preferred treatment for end-stage heart failure but the supply of donor hearts is insufficient to meet the need and many patients are not eligible for transplantation due to age or comorbid conditions. Implantable mechanical pumps can assist the circulation of blood by the ventricles. Left ventricular assist devices (LVADs) have been approved by the U.S. Food and Drug Administration (FDA) for use in patients awaiting transplant (a bridge to transplant) and as a last resort in patients with refractory heart failure who are not eligible for a heart transplant (destination therapy). In January 2010, the first newer generation, rotary continuous flow ventricular assist device (HeartMate II) was approved by the FDA for destination therapy. Eligibility criteria are essentially the same as those used to select patients for the pivotal clinical trial that included patients with shortness of breath and/or fatigue at rest or during minimal exertion despite treatment with optimal therapy for heart failure associated with a low ejection fraction (
Book Synopsis Cardiac Transplantation by : Niloo M. Edwards
Download or read book Cardiac Transplantation written by Niloo M. Edwards and published by Springer Science & Business Media. This book was released on 2004-02-26 with total page 253 pages. Available in PDF, EPUB and Kindle. Book excerpt: Leading physicians summarize in this easy-to-use and eminently practical handbook the day-to-day management of transplant donors and recipients at Columbia-Presbyterian Medical Center. Topics covered range from surgical techniques, pathology, and immunosuppression, to posttransplant management, pediatric heart transplantation, surgical alternatives, and mechanical circulatory assistance as a bridge to transplantation. The authors also discuss congenital transplant techniques, state-of-the-art perioperative management techniques and protocols, and UNOS regulation and nurse coordination.
Book Synopsis Quality of Life and Psychosomatics by : Wolfgang Albert
Download or read book Quality of Life and Psychosomatics written by Wolfgang Albert and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 211 pages. Available in PDF, EPUB and Kindle. Book excerpt: Advances in heart surgical treatment have been impressive in the last 15 years. In end-stage heart disease, procedures are now performed routinely which were only experimental one or two decades ago. Heart transplantation has become a well-established procedure. According to the Gen eral Registry of the International Society of Heart and Lung Transplantation. 40,738 heart transplantations had been performed through the end of 1997 with survival rates of 78 % at one year, 65 % at five years, and 42 % at ten years. The progress in this field has been due to intense efforts in understanding and modulating immune responses to the trans planted heart, to elaborate therapeutic strategies to constrain infections, and to improved out-patient care. Accordingly, heart transplantation is integrated into the facilities of the health care systems, the routine of physicians, and the awareness of patients. The resulting increase in potential organ recipients has not been met, however, by an equivalent increase of available donor organs. This increasing discrepancy has forced the technical improvement and clinical evalua tion of mechanical circulatory support systems as an option for treatment of critically ill patients with a failing heart. Initially, these assist devices were only used to maintain sufficient circulation in post-cardiotomy heart failure until myocardial function had recov ered. Since the late 1980s, their primary use has been that of bridging patients with heart failure until a suitable organ is available so that heart transplantation can be performed.
Book Synopsis Mechanical Circulatory Support Therapy in Advanced Heart Failure by : Mario C Deng
Download or read book Mechanical Circulatory Support Therapy in Advanced Heart Failure written by Mario C Deng and published by World Scientific. This book was released on 2007-03-28 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: This engaging book provides a state-of-the-art introduction to the rapidly evolving field of mechanical circulatory support therapy in the care of patients with advanced heart failure. It is aimed at healthcare teams around the world who are involved in patient care, research, and teaching of advanced heart failure; healthcare professionals in training; and interested lay persons. In particular, this book • serves as a comprehensive resource and practice guide on all aspects of mechanical circulatory support therapy, starting with an overview on heart failure management and then continuing with the referral and evaluation, the care before and after mechanical circulatory support implantation, the analysis of outcomes and complications, as well as a description of research and societal perspectives in the field of mechanical circulatory support therapy; • is founded on the expertise of Columbia University Medical Center (New York City), which has one of the most renowned heart failure, mechanical circulatory support, and heart transplantation programs in the world; • takes a multidisciplinary integrated healthcare team approach, including the perspectives of cardiologists, cardiac surgeons, nurses, coordinators, social workers, psychologists, physical therapists, financial experts, and bioethicists; and • provides in a unique way the complementary viewpoints from the expert healthcare team's as well as the patient's and family's perspectives, with patient vignettes interspersed throughout the entire text. Contents:Advanced Heart Failure:EpidemiologyIndividual Mechanical Circulatory Support DevicesEvaluation:Initial EncounterDestination Mechanical Circulatory SupportManagement:Intraoperative SituationLong-Term Follow-UpOutcomes:Outcome Assessment/PrognosticationHeartmateDeBakeyComplications:Bleeding/HemolysisRespiratory DysfunctionResearch Strategies:Basic and Translational ResearchDifferential Development by MCSD TypeSocietal Perspectives:Role of Governmental AgenciesEconomic Considerationsand other chapters Readership: Healthcare professionals: cardiologists, physicians, nurses, social workers, psychologists, financial workers; these professionals in teaching/education settings; interested lay public. Keywords:Heart Failure;Mechanical Circulatory Support;Left Ventricular Assist Device;Multidisciplinary Team;Patient PerspectiveKey Features:Provides complementary viewpoints on mechanical circulatory support device therapy in advanced heart failure from the perspectives of expert healthcare team as well as the patient and familyTakes a multidisciplinary integrated healthcare team approachServes as comprehensive resource for the expert practitioner and interested lay personFounded on the expertise infrastructure of one of the largest and most experienced heart failure, mechanical circulatory support and heart transplantation programs in the world
Book Synopsis Heart Transplantation by : Catherine T. Fleming
Download or read book Heart Transplantation written by Catherine T. Fleming and published by Nova Science Publishers. This book was released on 2009-07 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Cardiac transplantation is a widely accepted therapy for the treatment of end-stage congestive heart failure. Most candidates for cardiac transplantation have not been helped by conventional medical therapy and are excluded from other surgical options because of the poor condition of the heart. About 45% of the candidates have ischemic cardiomyopathy; however, this percentage is rising because of the increase in coronary artery disease in younger age groups. Of the candidates, 54% have some form of dilated cardiomyopathy, which often has an unclear origin. The remaining 1% of candidates fall into the category of other diseases, including congenital heart disease, that are not amenable to surgical correction. Candidacy determination and evaluation are key components of the process, as is post-operative follow-up care and immunosuppression management. This book presents leading research from around the world.
Book Synopsis Heart Transplantation by : Antonio Loforte
Download or read book Heart Transplantation written by Antonio Loforte and published by . This book was released on 2018-10-10 with total page 222 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Management of End-stage Heart Disease by : Eric A. Rose
Download or read book Management of End-stage Heart Disease written by Eric A. Rose and published by Springhouse Corporation. This book was released on 1998 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This practical manual seeks to address the need for broader, better management guidelines for end-stage heart disease. It contains both standard, time-tested methods, as well as more current, cutting-edge alternatives. There are medical therapies that utilize positive inotropic agents, adrenergic blocking agents and other drugs; surgical options, such as revascularization and valve surgery; myocardial replacement therapies that restore function through ventricular assist devices, flow pumps and artificial hearts; and myocardial enhancement therapies, including dynamic cardiomyoplasty and ventriculectomy.
Book Synopsis The Pathology of Cardiac Transplantation by : Ornella Leone
Download or read book The Pathology of Cardiac Transplantation written by Ornella Leone and published by Springer. This book was released on 2017-01-20 with total page 450 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is the first book to focus entirely on the role of pathology in cardiac transplantation, linked to the clinical perspective through clinical–pathological correlation, multidisciplinary team working, and collaborative research. It provides a scientific framework with up-to-date pathological protocols and classification schemes and guides the reader through the chronological phases of the transplant process in a step-by-step approach. Topics include end-stage heart failure with pathologies encountered in the native heart, current issues surrounding donor selection, the multiple faces of rejection pathology correlated with clinical management and immunology, other post-transplant complications, details of pediatric and combined heart/other organ transplantation, and a useful practical appendix. Many high-quality images and illustrative cases are presented, along with learning points and ample references. Transplantation medicine today is continuously changing as collaborative research into novel diagnostic techniques and immunosuppressive therapies translates into improved recipient management and survival. This book is aimed at practicing transplant pathologists and specialist trainees. It will also appeal to general pathologists and to physicians and surgeons involved in cardiac transplantation who need to understand the role of pathology in the clinical management of transplant recipients.
Author :U. S. Department of Veterans Affairs Publisher :Createspace Independent Pub ISBN 13 :9781489539755 Total Pages :48 pages Book Rating :4.5/5 (397 download)
Book Synopsis Use of Left Ventricular Assist Devices As Destination Therapy in End-Stage Congestive Heart Failure: a Systematic Review by : U. S. Department of Veterans Affairs
Download or read book Use of Left Ventricular Assist Devices As Destination Therapy in End-Stage Congestive Heart Failure: a Systematic Review written by U. S. Department of Veterans Affairs and published by Createspace Independent Pub. This book was released on 2013-05-22 with total page 48 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several common chronic conditions such as atherosclerotic heart disease and hypertension as well as other diseases can result in heart failure, a reduced ability of the heart to pump blood and maintain normal bodily functions. More than 100,000 people in the U.S. with progressive heart failure are refractory to available treatments and have high rates of hospitalization and mortality and a poor quality of life due to limited physical and social activities and psychological stress. Heart transplantation is currently the preferred treatment for end-stage heart failure. Unfortunately, the supply of donor hearts is far less than needed and many patients do not meet the criteria for heart transplantation primarily due to old age and comorbidities such as diabetes with damage to vital organs, pulmonary hypertension, renal insufficiency, malignancies and morbid obesity. Implantable mechanical pumps that assist the circulation of blood by one or both ventricles of the heart have evolved over several decades. Typically blood flows from the native left ventricle of the heart into the surgically implanted assist device and is pumped out into the aorta via an implanted conduit. Currently, long-term implantable left ventricular assist devices require an external source of power and control module. Surgical placement of a left ventricular assist device is increasingly done as a last resort for patients with refractory heart failure who are not eligible for heart transplantation, so called destination therapy. Some patients may improve after they receive a ventricular assist device as destination therapy and become eligible for heart transplantation even though this was not the initial therapeutic goal. A limited number may recover enough heart function to not need a heart transplant or mechanical assist device. Although survival with a newer generation continuous flow ventricular assist device is approaching that of a heart transplant, long-term use of the device by patients who are eligible for a heart transplant is not currently accepted practice. Conversely, many patients that receive a ventricular assist device as a bridge to transplant use the device for increasingly prolonged periods while waiting for a donated heart and some may become ineligible for a heart transplant. The purpose of this report is to review the scientific evidence for use of ventricular assist devices as destination therapy for patients with severe, refractory heart failure who are not eligible for heart transplantation at the time the device is implanted. Although many patients receive the same types of ventricular assist devices as a bridge to heart transplantation or recovery, the characteristics, hence risk profiles, of patients receiving bridge therapy are different from patients selected to receive a device as permanent destination therapy. Furthermore many bridged patients do receive a heart transplant that alters patient outcomes. This review focused on evidence about patient outcomes, patient selection and cost effectiveness of ventricular assist devices specifically intended as destination therapy. The primary goals of destination therapy are to: prolong survival, improve daily function and health-related quality of life, minimize harms including infection, major bleeding episodes, thromboembolic events including strokes and device malfunction or failure especially those that require hospital care. The key questions were: #1. How does use of an FDA-approved, current generation LVAD as destination therapy (i.e., the HeartMate II left ventricular assist device) effect patient outcomes? #2. What patient or site characteristics have been associated with patient benefits or harms when the FDA-approved, current generation LVAD is used as destination therapy? #3. What is the range of cost-effectiveness estimates of using the FDA-approved, current generation LVAD as destination therapy in end-stage heart failure and what explains variation in these estimates?
Book Synopsis Psychosocial Care of End-Stage Organ Disease and Transplant Patients by : Yelizaveta Sher
Download or read book Psychosocial Care of End-Stage Organ Disease and Transplant Patients written by Yelizaveta Sher and published by Springer. This book was released on 2018-12-05 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Th is book takes an integrated, evidence-based approach the psychiatricaspects of organ transplantation. Unlike any other text currently on the market, this title presents the core principles of transplant psychiatry through an organ-based structure that includes the heart, lungs, liver, GI organs, kidney, composite tissue, and other key areas of transplantation. Each section is divided into chapters discussing psychosocial, medical, and surgical considerations prior to and post-transplant, such as indications leading to a particular type of transplantation, medical course and complications aft er transplantation, psychiatric and psychosocial considerations before and aft er transplantation, history of each type of organ transplant, and any other special considerations. Th e text ends with special topics in care, including psychopharmacology, substance abuse, psychosocial evaluation of recipients and donors, ethical considerations, cross-cultural aspects, and building the transplant psychiatry practice. It includes excellent learning tools, including over 140 tables and figures for ease of use. Written by interdisciplinary experts, Psychosocial Care of End-Stage Disease and Transplant Patients is a valuable resource for students and medical professionals interested in psychiatry, psychology, psychosomatic medicine, transplant surgery, internists, hospital administrators, pharmacists, nurses, and social workers.
Book Synopsis Heart Failure: A Companion to Braunwald's Heart Disease E-Book by : G. Michael Felker
Download or read book Heart Failure: A Companion to Braunwald's Heart Disease E-Book written by G. Michael Felker and published by Elsevier Health Sciences. This book was released on 2019-02-06 with total page 784 pages. Available in PDF, EPUB and Kindle. Book excerpt: Up-to-date, authoritative and comprehensive, Heart Failure, 4th Edition, provides the clinically relevant information you need to effectively manage and treat patients with this complex cardiovascular problem. This fully revised companion to Braunwald’s Heart Disease helps you make the most of new drug therapies such as angiotensin receptor neprilysin inhibitors (ARNIs), recently improved implantable devices, and innovative patient management strategies. Led by internationally recognized heart failure experts Dr. G. Michael Felker and Dr. Douglas Mann, this outstanding reference gives health care providers the knowledge to improve clinical outcomes in heart failure patients. Focuses on a clinical approach to treating heart failure, resulting from a broad variety of cardiovascular problems. Covers the most recent guidelines and protocols, including significant new updates to ACC, AHA, and HFSA guidelines. Covers key topics such as biomarkers and precision medicine in heart failure and new data on angiotensin receptor neprilysin inhibitors (ARNIs). Contains four new chapters: Natriuretic Peptides in Heart Failure; Amyloidosis as a Cause of Heart Failure; HIV and Heart Failure; and Neuromodulation in Heart Failure. Covers the pathophysiological basis for the development and progression of heart failure. Serves as a definitive resource to prepare for the ABIM’s Heart Failure board exam. 2016 British Medical Association Award: First Prize, Cardiology (3rd Edition).
