Emerging Targets in Antibacterial and Antifungal Chemotherapy

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 1461532744
Total Pages : 619 pages
Book Rating : 4.4/5 (615 download)

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Book Synopsis Emerging Targets in Antibacterial and Antifungal Chemotherapy by : Joyce Sutcliffe

Download or read book Emerging Targets in Antibacterial and Antifungal Chemotherapy written by Joyce Sutcliffe and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 619 pages. Available in PDF, EPUB and Kindle. Book excerpt: Emerging Targets in Antibacterial and Antifungal Chemotherapy offers constructive ideas to researchers that could lead to the discovery of entirely new classes of drugs. The authors emphasize new topics rather than review work on known antibacterials and antifungals, and identify new targets--either the rate-limiting component of a biochemical pathway or a component of the pathway that is susceptible to a ``screening'' or ``rational drug design'' approach. Each chapter reviews the biochemical pathway and its place in the cellular scheme in order to place the target in perspective. The authors, a mixture of academic researchers and drug-discovery investigators in pharmaceutical companies, also extend these theoretical concerns into practical applications and suggest useful screening methodologies. The importance of this subject area is demonstrated by the increasing number of papers in the literature that point to potential targets and screening methodologies for new antibacterials. This book also deals with antifungals, investigating the inherent limitations in existing antifungals (many of which are extremely toxic or have only limited efficacy), and pointing to major developments in the discovery of novel antifungals. Emerging Targets in Antibacterial and Antifungal Chemotherapy will be of interest to professional microbiologists, biochemists, and cell biologists in both academic and industrial laboratories.

Antimicrobial Drug Discovery

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Publisher : CABI
ISBN 13 : 1845939433
Total Pages : 369 pages
Book Rating : 4.8/5 (459 download)

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Book Synopsis Antimicrobial Drug Discovery by : George Tegos

Download or read book Antimicrobial Drug Discovery written by George Tegos and published by CABI. This book was released on 2012 with total page 369 pages. Available in PDF, EPUB and Kindle. Book excerpt: Resistance is on the rise among a variety of human pathogenic microorganisms associated with common and potentially life-threatening infections, including penicillin-resistant Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). There is increasing demand to approach the threat of multidrug resistance incorporating novel multidisciplinary methodologies and technological platforms. This book documents the latest research, covering current and promising activities in four key areas: computational chemistry and chemoinformatics, High Throughput Screening (HTS), non-vertebrate model hosts and light and nano-based technologies. It is essential reading for researchers and students in microbiology, biotechnology, pharmacology, chemistry and biology as well as medical professionals.

Antimicrobial Chemotherapy

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Author :
Publisher : Oxford University Press, USA
ISBN 13 : 0199689776
Total Pages : 431 pages
Book Rating : 4.1/5 (996 download)

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Book Synopsis Antimicrobial Chemotherapy by : Peter G. Davey

Download or read book Antimicrobial Chemotherapy written by Peter G. Davey and published by Oxford University Press, USA. This book was released on 2015 with total page 431 pages. Available in PDF, EPUB and Kindle. Book excerpt: A valuable resource for undergraduates and graduates providing a thorough grounding in the scientific basis and clinical application of antimicrobial drugs. The new edition has been thoroughly updated to include the most recently licensed agents, including the treatment of HIV and contains guidance on prescribing and infection control practices.

Treating Infectious Diseases in a Microbial World

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Publisher : National Academies Press
ISBN 13 : 0309180686
Total Pages : 102 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Treating Infectious Diseases in a Microbial World by : National Research Council

Download or read book Treating Infectious Diseases in a Microbial World written by National Research Council and published by National Academies Press. This book was released on 2006-01-03 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Humans coexist with millions of harmless microorganisms, but emerging diseases, resistance to antibiotics, and the threat of bioterrorism are forcing scientists to look for new ways to confront the microbes that do pose a danger. This report identifies innovative approaches to the development of antimicrobial drugs and vaccines based on a greater understanding of how the human immune system interacts with both good and bad microbes. The report concludes that the development of a single superdrug to fight all infectious agents is unrealistic.

Current Catalog

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Publisher :
ISBN 13 :
Total Pages : 666 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Current Catalog by : National Library of Medicine (U.S.)

Download or read book Current Catalog written by National Library of Medicine (U.S.) and published by . This book was released on 1992 with total page 666 pages. Available in PDF, EPUB and Kindle. Book excerpt: First multi-year cumulation covers six years: 1965-70.

Biological Inhibitors

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Publisher : CRC Press
ISBN 13 : 1000102815
Total Pages : 393 pages
Book Rating : 4.0/5 (1 download)

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Book Synopsis Biological Inhibitors by : M. Iqbal Choudhary

Download or read book Biological Inhibitors written by M. Iqbal Choudhary and published by CRC Press. This book was released on 2020-08-18 with total page 393 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book, a part of the series Studies in Medicinal Chemistry, details the biological inhibitors that reflect drug discovery in treating human diseases, including cardiovascular, nervous, inflammatory, hormonal and metabolic processes. Compounds for fungal diseases and HIV/AIDS are also covered.

Antifungal Therapy

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Publisher : CRC Press
ISBN 13 : 0849387868
Total Pages : 484 pages
Book Rating : 4.8/5 (493 download)

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Book Synopsis Antifungal Therapy by : Mahmoud Ghannoum

Download or read book Antifungal Therapy written by Mahmoud Ghannoum and published by CRC Press. This book was released on 2016-04-19 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c

Plant-Derived Antimycotics

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Publisher : CRC Press
ISBN 13 : 9781560229278
Total Pages : 622 pages
Book Rating : 4.2/5 (292 download)

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Book Synopsis Plant-Derived Antimycotics by : M.k. Rai

Download or read book Plant-Derived Antimycotics written by M.k. Rai and published by CRC Press. This book was released on 2003-05-29 with total page 622 pages. Available in PDF, EPUB and Kindle. Book excerpt: An important overview of the state of the art in naturally occurring antimycotics! Here is a comprehensive and innovative examination of the antimycotic potential of essential plant oils and extracts against fungal infections affecting humans, animals, plants, and foodstuffs. Plant-Derived Antimycotics emphasizes the antimycotic activity of plants found in Central America, India, Nepal, Fiji, and China--areas rich in phyto-diversity and traditional botanical/medical knowledge. From editor M.K. Rai: “Since the inception of human civilization men have been using herbs against various mycotic infections. In the recent past, several antimycotic agents have been introduced into the market due to their rapid curative properties. Still, the quest for new antifungal agents of a fungicidal rather than fungistatic nature continues. Furthermore, there has been a dramatic increase in the new spectrum of fungal infections known as opportunistic fungal pathogens. Consequently, plant-derived antimycotics are gaining importance, being natural, cheaper, safer, eco-friendly, and within the reach of the common man.” With a distinguished list of contributors from around the world, Plant-Derived Antimycotics explores: antifungal compounds that strengthen plant-defense systems traditional herbs that have revealed their antifungal properties newer, faster methods of screening and evaluating antifungal drugs natural antimycotics derived from plants in Croatia, South America, South Africa, China, India, and Fiji the mechanism of herbal antimycotic action the diversity of antimycotic efficacy in Asteraceous and Meliaceous plants new bioactive antifungal molecules Plant-Derived Antimycotics is an essential reference for pharmacologists, microbiologists, clinical mycologists, oncologists, immunologists, drug manufacturers, botanists and ethnobotanists, phytochemists, herbalists, and everyone searching for a natural remedy for the new spectrum of opportunistic fungal infections generated by the immunocompromising difficulties encountered by AIDS and cancer patients. Color illustrations, photographs, charts, tables, and graphs make the information easier to absorb and understand.

Antibiotics in Laboratory Medicine

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 9780781749831
Total Pages : 924 pages
Book Rating : 4.7/5 (498 download)

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Book Synopsis Antibiotics in Laboratory Medicine by : Victor Lorian

Download or read book Antibiotics in Laboratory Medicine written by Victor Lorian and published by Lippincott Williams & Wilkins. This book was released on 2005 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt: Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference. Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.

Fungal Biotechnology in Agricultural, Food, and Environmental Applications

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Publisher : CRC Press
ISBN 13 : 082475879X
Total Pages : 856 pages
Book Rating : 4.8/5 (247 download)

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Book Synopsis Fungal Biotechnology in Agricultural, Food, and Environmental Applications by : Dilip K. Arora

Download or read book Fungal Biotechnology in Agricultural, Food, and Environmental Applications written by Dilip K. Arora and published by CRC Press. This book was released on 2003-12-17 with total page 856 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contributions from 80 world-renowned authorities representing a broad international background lend Fungal Biotechnology in Agricultural, Food, and Environmental Applicationsfirst-class information on the biotechnological potential of entomopathogenic fungi and ergot alkaloids, applications of Trichoderma in disease control, and the development of mycoherbicides. Additional topics include fungal control of nematodes, control of plant disease by arbuscular mycorrhizal fungi, strategies for controlling vegetable and fruit crops, molecular biology tactics with mycotoxigenic fungi and the development of biofungicides, production of edible fungi, fermented foods, and high-value products like mycoprotein.

Annual Reports in Medicinal Chemistry

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Publisher : Academic Press
ISBN 13 : 0080583768
Total Pages : 392 pages
Book Rating : 4.0/5 (85 download)

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Book Synopsis Annual Reports in Medicinal Chemistry by :

Download or read book Annual Reports in Medicinal Chemistry written by and published by Academic Press. This book was released on 1997-10-08 with total page 392 pages. Available in PDF, EPUB and Kindle. Book excerpt: Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences, which are expectedto provide the basis for entirely new future therapies.

New Antibiotic Targets

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Publisher : Springer Science & Business Media
ISBN 13 : 1588299155
Total Pages : 274 pages
Book Rating : 4.5/5 (882 download)

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Book Synopsis New Antibiotic Targets by : W. Scott Champney

Download or read book New Antibiotic Targets written by W. Scott Champney and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies. The book will provide laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

Molecular Basis of Drug Design and Resistance

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Publisher : Cambridge University Press
ISBN 13 : 9780521626699
Total Pages : 172 pages
Book Rating : 4.6/5 (266 download)

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Book Synopsis Molecular Basis of Drug Design and Resistance by : G. H. Coombs

Download or read book Molecular Basis of Drug Design and Resistance written by G. H. Coombs and published by Cambridge University Press. This book was released on 1997 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume is the specially commissioned supplement to the journal Parasitology, volume 114.

Discovery of Novel Natural Products with Therapeutic Potential

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Publisher : Newnes
ISBN 13 : 1483292134
Total Pages : 480 pages
Book Rating : 4.4/5 (832 download)

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Book Synopsis Discovery of Novel Natural Products with Therapeutic Potential by : Vincent P. Gullo

Download or read book Discovery of Novel Natural Products with Therapeutic Potential written by Vincent P. Gullo and published by Newnes. This book was released on 2013-10-22 with total page 480 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

Infectious Diseases in Immunocompromised Hosts

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Publisher : CRC Press
ISBN 13 : 9780849385537
Total Pages : 1238 pages
Book Rating : 4.3/5 (855 download)

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Book Synopsis Infectious Diseases in Immunocompromised Hosts by : Vassil St. Georgiev

Download or read book Infectious Diseases in Immunocompromised Hosts written by Vassil St. Georgiev and published by CRC Press. This book was released on 1997-12-29 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt: Because of limited access to medical libraries and medical journals, the majority of clinicians may find it difficult to keep informed on the latest developments in drug manufacture and treatment of infectious diseases in immunocompromised patients. This new handbook strives to fulfill the need for information in this area of medicine. This is the first book on drug development and treatment of infectious diseases in immunocompromised hosts. It integrates both results from large-scale clinical trials and single cases as well as small groups of patients. It covers bacterial, viral, parasitic, and fungal infections, including a wide array of diseases. Infectious Diseases in Immunocompromised Hosts encompasses not only opportunistic infections associated exclusively with immunocompromised patients, but also common infections that become life-threatening for immunosuppressed individuals.

Antibiotics

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Publisher : Springer Science & Business Media
ISBN 13 : 147579200X
Total Pages : 283 pages
Book Rating : 4.4/5 (757 download)

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Book Synopsis Antibiotics by : G.G. Gallo

Download or read book Antibiotics written by G.G. Gallo and published by Springer Science & Business Media. This book was released on 2013-06-29 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this translation of the Italian second edition, the authors provide a comprehensive account of the current knowledge on antibiotics. They concisely describe how various scientific disciplines are involved in antibiotics research, development, and use. Their work also discusses the industrial and clinical development of new antibiotics, as well as the questions and controversies related to the function of antibiotics in nature. Antibiotics is richly illustrated with clear chemical structures, drawings, diagrams, and synoptical tables.

Foye's Principles of Medicinal Chemistry

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 0683307371
Total Pages : 1136 pages
Book Rating : 4.6/5 (833 download)

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Book Synopsis Foye's Principles of Medicinal Chemistry by : David A. Williams

Download or read book Foye's Principles of Medicinal Chemistry written by David A. Williams and published by Lippincott Williams & Wilkins. This book was released on 2002 with total page 1136 pages. Available in PDF, EPUB and Kindle. Book excerpt: This comprehensive Fifth Edition has been fully revised and updated to meet the changing curricula of medicinal chemistry courses. The new emphasis is on pharmaceutical care that focuses on the patient, and on the pharmacist a therapeutic clinical consultant, rather than chemist. Approximately 45 contributors, respected in the field of pharmacy education, augment this exhaustive reference. New to this edition are chapters with standardized formats and features, such as Case Studies, Therapeutic Actions, Drug Interactions, and more. Over 700 illustrations supplement this must-have resource.