Drug Repurposing Against SARS-CoV-2

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 981512319X
Total Pages : 206 pages
Book Rating : 4.8/5 (151 download)

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Book Synopsis Drug Repurposing Against SARS-CoV-2 by : Tabish Qidwai

Download or read book Drug Repurposing Against SARS-CoV-2 written by Tabish Qidwai and published by Bentham Science Publishers. This book was released on 2023-04-14 with total page 206 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing is a cost-effective method of discovering new treatments for diseases than traditional drug development methods. It involves virtual screening of chemical candidates with the aid of computational methods like molecular docking. Drug Repurposing against SARS-CoV2 focuses on current trends in drug repurposing against the novel coronavirus strains. The book aims to give readers an overview of drug repurposing against COVID-19 and various techniques involved in the process. The book consolidates available information on the pathophysiology, drug targets, and drug repurposing against COVID-19 into a single, convenient resource. Key features • An up-to-date compilation of the evidence that supports the drug repurposing for COVID-19. • How to use repurposing of available drugs for disease therapy. • Provides an improved understanding of pathophysiology and SARS-CoV2 viral entry pathways. • Provides references for further reading

Drug Repurposing for COVID-19 Therapy

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Author :
Publisher : Frontiers Media SA
ISBN 13 : 2889714853
Total Pages : 588 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Drug Repurposing for COVID-19 Therapy by : Filippo Drago

Download or read book Drug Repurposing for COVID-19 Therapy written by Filippo Drago and published by Frontiers Media SA. This book was released on 2021-10-14 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Drug Repurposing Against SARS-CoV-2

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Author :
Publisher : Bentham Science Publishers
ISBN 13 : 9789815123210
Total Pages : 0 pages
Book Rating : 4.1/5 (232 download)

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Book Synopsis Drug Repurposing Against SARS-CoV-2 by : Tabish Qidwai

Download or read book Drug Repurposing Against SARS-CoV-2 written by Tabish Qidwai and published by Bentham Science Publishers. This book was released on 2023-04-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing is a cost-effective method of discovering new treatments for diseases than traditional drug development methods. It involves virtual screening of chemical candidates with the aid of computational methods like molecular docking. Drug Repurposing against SARS-CoV2 focuses on current trends in drug repurposing against the novel coronavirus strains. The book aims to give readers an overview of drug repurposing against COVID-19 and various techniques involved in the process. The book consolidates available information on the pathophysiology, drug targets, and drug repurposing against COVID-19 into a single, convenient resource. Key features - An up-to-date compilation of the evidence that supports the drug repurposing for COVID-19. - How to use repurposing of available drugs for disease therapy. - Provides an improved understanding of pathophysiology and SARS-CoV2 viral entry pathways. - Provides references for further reading

Drug Repurposing Against SARS-CoV2

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Author :
Publisher :
ISBN 13 : 9789815123203
Total Pages : 0 pages
Book Rating : 4.1/5 (232 download)

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Book Synopsis Drug Repurposing Against SARS-CoV2 by : Tabish Qidwai

Download or read book Drug Repurposing Against SARS-CoV2 written by Tabish Qidwai and published by . This book was released on 2023-04-14 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing is a cost-effective method of discovering new treatments for diseases than traditional drug development methods. It involves virtual screening of chemical candidates with the aid of computational methods like molecular docking. Drug Repurposing against SARS-CoV2 focuses on current trends in drug repurposing against the novel coronavirus strains. The book aims to give readers an overview of drug repurposing against COVID-19 and various techniques involved in the process. The book consolidates available information on the pathophysiology, drug targets, and drug repurposing against COVID-19 into a single, convenient resource. Key features * An up-to-date compilation of the evidence that supports the drug repurposing for COVID-19. * How to use repurposing of available drugs for disease therapy. * Provides an improved understanding of pathophysiology and SARS-CoV2 viral entry pathways. * Provides references for further reading

Hydroxychloroquine and Chloroquine Retinopathy

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Author :
Publisher : Springer
ISBN 13 : 149390597X
Total Pages : 303 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Hydroxychloroquine and Chloroquine Retinopathy by : David J. Browning

Download or read book Hydroxychloroquine and Chloroquine Retinopathy written by David J. Browning and published by Springer. This book was released on 2014-05-09 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: Malpractice settlements are large for undetected hydroxychloroquine and chloroquine toxicity which, if untreated, can lead to permanent loss of central vision. Knowledge of the ocular toxicity of these drugs has increased during the past fifty years as their use has expanded. Hydroxychloroquine and Chloroquine Retinopathy is the first single-source book on the subject and is essential for the practicing ophthalmologists, rheumatologists, dermatologists, and internists who prescribe these drugs. It covers clinical topics such as signs and symptoms of toxicity, toxicity screening, ancillary testing, to whom and why the drugs are prescribed and dosing considerations. Additionally, the book addresses practice management considerations, including coding, reimbursement and equipment costs, and the medico-legal responsibilities of the rheumatologist and of the ophthalmologist. Guidelines for the management of hydroxychloroquine and chloroquine vary around the world and differences between the guidelines of the United Kingdom, the United States, and other countries are identified. The book concludes with a collection of case examples illustrating common clinical scenarios and their management. This book is a “must-have” resource for physicians who use these drugs.

Drug Repurposing

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Author :
Publisher : BoD – Books on Demand
ISBN 13 : 1839685204
Total Pages : 236 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Drug Repurposing by : Farid A. Badria

Download or read book Drug Repurposing written by Farid A. Badria and published by BoD – Books on Demand. This book was released on 2020-12-02 with total page 236 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses on the hypothesis, risk/benefits, and economic impacts of drug repurposing on drug discovery in dermatology, infectious diseases, neurological disorders, cancer, and orphan diseases. It brings together up-to-date research to provide readers with an informative, illustrative, and easy-to-read book useful for students, clinicians, and the pharmaceutical industry.

Network Medicine

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Author :
Publisher : Harvard University Press
ISBN 13 : 0674436539
Total Pages : 449 pages
Book Rating : 4.6/5 (744 download)

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Book Synopsis Network Medicine by : Joseph Loscalzo

Download or read book Network Medicine written by Joseph Loscalzo and published by Harvard University Press. This book was released on 2017-02-01 with total page 449 pages. Available in PDF, EPUB and Kindle. Book excerpt: Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. With contributions from leading experts, Network Medicine introduces this rapidly evolving field of research, which promises to revolutionize the diagnosis and treatment of human diseases.

Modeling, Control and Drug Development for COVID-19 Outbreak Prevention

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Author :
Publisher : Springer
ISBN 13 : 9783030728366
Total Pages : 0 pages
Book Rating : 4.7/5 (283 download)

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Book Synopsis Modeling, Control and Drug Development for COVID-19 Outbreak Prevention by : Ahmad Taher Azar

Download or read book Modeling, Control and Drug Development for COVID-19 Outbreak Prevention written by Ahmad Taher Azar and published by Springer. This book was released on 2022-11-03 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is well-structured book which consists of 31 full chapters. The book chapters' deal with the recent research problems in the areas of modeling, control and drug development, and it presents various techniques of COVID-19 outbreak prevention modeling. The book also concentrates on computational simulations that may help speed up the development of drugs to counter the novel coronavirus responsible for COVID-19. This is an open access book.

In Silico Modeling of Drugs Against Coronaviruses

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Author :
Publisher :
ISBN 13 : 9781071613665
Total Pages : 788 pages
Book Rating : 4.6/5 (136 download)

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Book Synopsis In Silico Modeling of Drugs Against Coronaviruses by : Kunal Roy

Download or read book In Silico Modeling of Drugs Against Coronaviruses written by Kunal Roy and published by . This book was released on 2021 with total page 788 pages. Available in PDF, EPUB and Kindle. Book excerpt: This essential volume explores a variety of tools and protocols of structure-based (homology modeling, molecular docking, molecular dynamics, protein-protein interaction network) and ligand-based (pharmacophore mapping, quantitative structure-activity relationships or QSARs) drug design for ranking and prioritization of candidate molecules in search of effective treatment strategy against coronaviruses. Beginning with an introductory section that discusses coronavirus interactions with humanity and COVID-19 in particular, the book then continues with sections on tools and methodologies, literature reports and case studies, as well as online tools and databases that can be used for computational anti-coronavirus drug research. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of practical detail and implementation advice that ensures high quality results in the lab. Comprehensive and timely, In Silico Modeling of Drugs Against Coronaviruses: Computational Tools and Protocols is an ideal reference for researchers working on the development of novel anti-coronavirus drugs for SARS-CoV-2 and for coronaviruses that will likely appear in the future.

Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis

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Author :
Publisher : Springer Nature
ISBN 13 : 9811585342
Total Pages : 436 pages
Book Rating : 4.8/5 (115 download)

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Book Synopsis Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis by : Khalid Raza

Download or read book Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis written by Khalid Raza and published by Springer Nature. This book was released on 2020-10-16 with total page 436 pages. Available in PDF, EPUB and Kindle. Book excerpt: The novel coronavirus disease 2019 (COVID-19) pandemic has posed a major threat to human life and health. This book is beneficial for interdisciplinary students, researchers, and professionals to understand COVID-19 and how computational intelligence can be used for the purpose of surveillance, control, prevention, prediction, diagnosis, and potential treatment of the disease. The book contains different aspects of COVID-19 that includes fundamental knowledge, epidemic forecast models, surveillance and tracking systems, IoT- and IoMT-based integrated systems for COVID-19, social network analysis systems for COVID-19, radiological images (CT, X-ray) based diagnosis system, and computational intelligence and in silico drug design and drug repurposing methods against COVID-19 patients. The contributing authors of this volume are experts in their fields and they are from various reputed universities and institutions across the world. This volume is a valuable and comprehensive resource for computer and data scientists, epidemiologists, radiologists, doctors, clinicians, pharmaceutical professionals, along with graduate and research students of interdisciplinary and multidisciplinary sciences.

Coronavirus Replication and Reverse Genetics

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 9783540214946
Total Pages : 278 pages
Book Rating : 4.2/5 (149 download)

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Book Synopsis Coronavirus Replication and Reverse Genetics by : Luis Enjuanes

Download or read book Coronavirus Replication and Reverse Genetics written by Luis Enjuanes and published by Springer Science & Business Media. This book was released on 2004-10-05 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human coronaviruses caused the SARS epidemic that infected more than 8000 people, killing about ten percent of them in 32 countries. This book provides essential information on these viruses and the development of vaccines to control coronavirus infections.

Application of Natural Products in SARS-CoV-2

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Author :
Publisher : Elsevier
ISBN 13 : 0323950485
Total Pages : 548 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Application of Natural Products in SARS-CoV-2 by : Kamal Niaz

Download or read book Application of Natural Products in SARS-CoV-2 written by Kamal Niaz and published by Elsevier. This book was released on 2022-10-20 with total page 548 pages. Available in PDF, EPUB and Kindle. Book excerpt: Application of Natural Products in SARS-CoV-2 examines the potential for natural products to treat COVID-19, bringing together the most recent research. SARS-CoV-2 is a novel disease H54 that is still being researched despite being globally prevalent. There are still few proven treatments, so repurposing existing drugs and treatments is essential. While there have been many articles published on the subject, this book is the first to bring together data and research on the topic. It includes information about molecular mechanism, dosage and safety profiles, and an essential resource for all scientists and researchers working to combat SARS-CoV-2. Collates known data and research on COVID-19 and natural products in a single and easy to find place Includes information about molecular mechanism, dosage and safety profiles Provides information from a diverse group of academics and industrial scientists

Viral Proteases and Their Inhibitors

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Publisher : Academic Press
ISBN 13 : 0128096829
Total Pages : 516 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Viral Proteases and Their Inhibitors by : Satya Prakash Gupta

Download or read book Viral Proteases and Their Inhibitors written by Satya Prakash Gupta and published by Academic Press. This book was released on 2017-07-03 with total page 516 pages. Available in PDF, EPUB and Kindle. Book excerpt: Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases

Some Drugs and Herbal Products

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Publisher :
ISBN 13 :
Total Pages : 0 pages
Book Rating : 4.:/5 (972 download)

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Book Synopsis Some Drugs and Herbal Products by :

Download or read book Some Drugs and Herbal Products written by and published by . This book was released on 2016 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume of the IARC Monographs provides an assessment of the carcinogenicity of 14 drugs and herbal products. The IARC Monographs Working Group relied on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension). Other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): Aloe vera whole leaf extract, goldenseal root powder, Ginkgo biloba leaf extract, kava extract, and pulegone. In view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.

Coronavirus Drug Discovery

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Author :
Publisher : Elsevier
ISBN 13 : 0323955797
Total Pages : 408 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Coronavirus Drug Discovery by : Chukwuebuka Egbuna

Download or read book Coronavirus Drug Discovery written by Chukwuebuka Egbuna and published by Elsevier. This book was released on 2022-07-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health. In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful. Discusses the pathogenic mechanisms of SARS-CoV-2 and druggable targets Reviews the various signaling pathways associated with SAR-CoV-2 as possible druggable targets Presents computational approaches and in silico studies against SARS-CoV-2

Bioinformatics Research and Development

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Publisher : Springer
ISBN 13 : 354071233X
Total Pages : 482 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Bioinformatics Research and Development by : Sepp Hochreiter

Download or read book Bioinformatics Research and Development written by Sepp Hochreiter and published by Springer. This book was released on 2007-05-21 with total page 482 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the First International Bioinformatics Research and Development Conference, BIRD 2007, held in Berlin, Germany in March 2007. The 36 revised full papers are organized in topical sections on microarray and systems biology and networks, medical, SNPs, genomics, systems biology, sequence analysis and coding, proteomics and structure, databases, Web and text analysis.

Free Energy Calculations

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Author :
Publisher : Springer Science & Business Media
ISBN 13 : 3540384472
Total Pages : 528 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Free Energy Calculations by : Christophe Chipot

Download or read book Free Energy Calculations written by Christophe Chipot and published by Springer Science & Business Media. This book was released on 2007-01-08 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Free energy constitutes the most important thermodynamic quantity to understand how chemical species recognize each other, associate or react. Examples of problems in which knowledge of the underlying free energy behaviour is required, include conformational equilibria and molecular association, partitioning between immiscible liquids, receptor-drug interaction, protein-protein and protein-DNA association, and protein stability. This volume sets out to present a coherent and comprehensive account of the concepts that underlie different approaches devised for the determination of free energies. The reader will gain the necessary insight into the theoretical and computational foundations of the subject and will be presented with relevant applications from molecular-level modelling and simulations of chemical and biological systems. Both formally accurate and approximate methods are covered using both classical and quantum mechanical descriptions. A central theme of the book is that the wide variety of free energy calculation techniques available today can be understood as different implementations of a few basic principles. The book is aimed at a broad readership of graduate students and researchers having a background in chemistry, physics, engineering and physical biology.