Dna Decipher Journal Volume 4 Issue 3

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The World Within Us (Or A Sketch of Consciousness Space Beyond Freudian Mental Model and Implications to Socio-Economics Modeling and Integrative Cancer Therapy)

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Author : Victor Christianto
Publisher : Infinite Study
ISBN 13 :
Total Pages : 13 pages
Book Rating : 4./5 ( download)

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Book Synopsis The World Within Us (Or A Sketch of Consciousness Space Beyond Freudian Mental Model and Implications to Socio-Economics Modeling and Integrative Cancer Therapy) by : Victor Christianto

Download or read book The World Within Us (Or A Sketch of Consciousness Space Beyond Freudian Mental Model and Implications to Socio-Economics Modeling and Integrative Cancer Therapy) written by Victor Christianto and published by Infinite Study. This book was released on with total page 13 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this paper, we give an outline of an ongoing study to go beyond Freudian mental archetypal model. First, we discuss the essence of numerous problems that we suffer in our sophisticated and modernized society. Then we discuss possibility to reintroduce spirit into human consciousness. While we are aware that much remain to be done and we admit that this is only a sketch, we hope that this paper will start a fresh approach of research towards more realistic nonlinear consciousness model with wide ranging implications to socio-economic modeling and also integrative cancer therapy. At the last section we also shortly outline plausible method to vindicate our proposed boson-fermion model of human society in a physical experiment.

Collected Papers. Volume VIII

Author : Florentin Smarandache
Publisher : Infinite Study
ISBN 13 :
Total Pages : 1002 pages
Book Rating : 4./5 ( download)

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Book Synopsis Collected Papers. Volume VIII by : Florentin Smarandache

Download or read book Collected Papers. Volume VIII written by Florentin Smarandache and published by Infinite Study. This book was released on 2022-04-01 with total page 1002 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eighth volume of Collected Papers includes 75 papers comprising 973 pages on (theoretic and applied) neutrosophics, written between 2010-2022 by the author alone or in collaboration with the following 102 co-authors (alphabetically ordered) from 24 countries: Mohamed Abdel-Basset, Abduallah Gamal, Firoz Ahmad, Ahmad Yusuf Adhami, Ahmed B. Al-Nafee, Ali Hassan, Mumtaz Ali, Akbar Rezaei, Assia Bakali, Ayoub Bahnasse, Azeddine Elhassouny, Durga Banerjee, Romualdas Bausys, Mircea Boșcoianu, Traian Alexandru Buda, Bui Cong Cuong, Emilia Calefariu, Ahmet Çevik, Chang Su Kim, Victor Christianto, Dae Wan Kim, Daud Ahmad, Arindam Dey, Partha Pratim Dey, Mamouni Dhar, H. A. Elagamy, Ahmed K. Essa, Sudipta Gayen, Bibhas C. Giri, Daniela Gîfu, Noel Batista Hernández, Hojjatollah Farahani, Huda E. Khalid, Irfan Deli, Saeid Jafari, Tèmítópé Gbóláhàn Jaíyéolá, Sripati Jha, Sudan Jha, Ilanthenral Kandasamy, W.B. Vasantha Kandasamy, Darjan Karabašević, M. Karthika, Kawther F. Alhasan, Giruta Kazakeviciute-Januskeviciene, Qaisar Khan, Kishore Kumar P K, Prem Kumar Singh, Ranjan Kumar, Maikel Leyva-Vázquez, Mahmoud Ismail, Tahir Mahmood, Hafsa Masood Malik, Mohammad Abobala, Mai Mohamed, Gunasekaran Manogaran, Seema Mehra, Kalyan Mondal, Mohamed Talea, Mullai Murugappan, Muhammad Akram, Muhammad Aslam Malik, Muhammad Khalid Mahmood, Nivetha Martin, Durga Nagarajan, Nguyen Van Dinh, Nguyen Xuan Thao, Lewis Nkenyereya, Jagan M. Obbineni, M. Parimala, S. K. Patro, Peide Liu, Pham Hong Phong, Surapati Pramanik, Gyanendra Prasad Joshi, Quek Shio Gai, R. Radha, A.A. Salama, S. Satham Hussain, Mehmet Șahin, Said Broumi, Ganeshsree Selvachandran, Selvaraj Ganesan, Shahbaz Ali, Shouzhen Zeng, Manjeet Singh, A. Stanis Arul Mary, Dragiša Stanujkić, Yusuf Șubaș, Rui-Pu Tan, Mirela Teodorescu, Selçuk Topal, Zenonas Turskis, Vakkas Uluçay, Norberto Valcárcel Izquierdo, V. Venkateswara Rao, Volkan Duran, Ying Li, Young Bae Jun, Wadei F. Al-Omeri, Jian-qiang Wang, Lihshing Leigh Wang, Edmundas Kazimieras Zavadskas.

Collected Papers. Volume XI

Author : Florentin Smarandache
Publisher : Infinite Study
ISBN 13 :
Total Pages : 1018 pages
Book Rating : 4./5 ( download)

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Book Synopsis Collected Papers. Volume XI by : Florentin Smarandache

Download or read book Collected Papers. Volume XI written by Florentin Smarandache and published by Infinite Study. This book was released on 2022-08-01 with total page 1018 pages. Available in PDF, EPUB and Kindle. Book excerpt: This eleventh volume of Collected Papers includes 90 papers comprising 988 pages on Physics, Artificial Intelligence, Health Issues, Decision Making, Economics, Statistics, written between 2001-2022 by the author alone or in collaboration with the following 84 co-authors (alphabetically ordered) from 19 countries: Abhijit Saha, Abu Suﬁan, Jack Allen, Shahbaz Ali, Ali Safaa Sadiq, Aliya Fahmi, Atiqa Fakhar, Atiqa Firdous, Sukanto Bhattacharya, Robert N. Boyd, Victor Chang, Victor Christianto, V. Christy, Dao The Son, Debjit Dutta, Azeddine Elhassouny, Fazal Ghani, Fazli Amin, Anirudha Ghosha, Nasruddin Hassan, Hoang Viet Long, Jhulaneswar Baidya, Jin Kim, Jun Ye, Darjan Karabašević, Vasilios N. Katsikis, Ieva Meidutė-Kavaliauskienė, F. Kaymarm, Nour Eldeen M. Khalifa, Madad Khan, Qaisar Khan, M. Khoshnevisan, Kifayat Ullah,, Volodymyr Krasnoholovets, Mukesh Kumar, Le Hoang Son, Luong Thi Hong Lan, Tahir Mahmood, Mahmoud Ismail, Mohamed Abdel-Basset, Siti Nurul Fitriah Mohamad, Mohamed Loey, Mai Mohamed, K. Mohana, Kalyan Mondal, Muhammad Gulfam, Muhammad Khalid Mahmood, Muhammad Jamil, Muhammad Yaqub Khan, Muhammad Riaz, Nguyen Dinh Hoa, Cu Nguyen Giap, Nguyen Tho Thong, Peide Liu, Pham Huy Thong, Gabrijela Popović, Surapati Pramanik, Dmitri Rabounski, Roslan Hasni, Rumi Roy, Tapan Kumar Roy, Said Broumi, Saleem Abdullah, Muzafer Saračević, Ganeshsree Selvachandran, Shariful Alam, Shyamal Dalapati, Housila P. Singh, R. Singh, Rajesh Singh, Predrag S. Stanimirović, Kasan Susilo, Dragiša Stanujkić, Alexandra Şandru, Ovidiu Ilie Şandru, Zenonas Turskis, Yunita Umniyati, Alptekin Ulutaș, Maikel Yelandi Leyva Vázquez, Binyamin Yusoff, Edmundas Kazimieras Zavadskas, Zhao Loon Wang.

Topological Geometrodynamics

Author : Matti Pitkanen
Publisher : Bentham Science Publishers
ISBN 13 : 1681081792
Total Pages : 1235 pages
Book Rating : 4.6/5 (81 download)

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Book Synopsis Topological Geometrodynamics by : Matti Pitkanen

Download or read book Topological Geometrodynamics written by Matti Pitkanen and published by Bentham Science Publishers. This book was released on 2016-03-03 with total page 1235 pages. Available in PDF, EPUB and Kindle. Book excerpt: Topological geometrodynamics (TGD) is a modification of the theory of general relativity inspired by the problems related to the definition of inertial and gravitational energies in the earlier hypotheses. TGD is also a generalization of super string models. TGD brings forth an elegant theoretical projection of reality and builds upon the work by renowned scientists (Wheeler, Feynman, Penrose, Einstein, Josephson to name a few). In TGD, Physical space-time planes are visualized as four-dimensional surfaces in a certain 8-dimensional space (H). The choice of H is fixed by symmetries of standard model and leads to a geometric mapping of known classical fields and elementary particle numbers. TGD differs from Einstein’s geometrodynamics in the way space-time planes or ‘sheets’ are lumped together. Extending the theory based on fusing number concepts implies a further generalisation of the space-time concept allowing the identification of space-time correlates of cognition and intentionality. Additionally, zero energy ontology forces an extension of quantum measurement theory to a theory of consciousness and a hierarchy of phases is identified. Dark matter is thus predicted with far reaching implications for the understanding of consciousness and living systems. Therefore, it sets a solid foundation for modeling our universe in geometric terms. Topological Geometrodynamics: An Overview explains basic and advanced concepts about TGD. The book covers introductory information and classical TGD concepts before delving into twistor-space theory, particle physics, infinite-dimensional spinor geometry, generalized number theory, Planck constants, and the applications of TGD theory in research. The book is a valuable guide to TDG theory for researchers and advanced graduates in theoretical physics and cosmology.

Fundamentals of Forensic DNA Typing

Author : John M. Butler
Publisher : Academic Press
ISBN 13 : 0080961762
Total Pages : 519 pages
Book Rating : 4.0/5 (89 download)

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Book Synopsis Fundamentals of Forensic DNA Typing by : John M. Butler

Download or read book Fundamentals of Forensic DNA Typing written by John M. Butler and published by Academic Press. This book was released on 2009-09-30 with total page 519 pages. Available in PDF, EPUB and Kindle. Book excerpt: Fundamentals of Forensic DNA Typing is written with a broad viewpoint. It examines the methods of current forensic DNA typing, focusing on short tandem repeats (STRs). It encompasses current forensic DNA analysis methods, as well as biology, technology and genetic interpretation. This book reviews the methods of forensic DNA testing used in the first two decades since early 1980's, and it offers perspectives on future trends in this field, including new genetic markers and new technologies. Furthermore, it explains the process of DNA testing from collection of samples through DNA extraction, DNA quantitation, DNA amplification, and statistical interpretation. The book also discusses DNA databases, which play an important role in law enforcement investigations. In addition, there is a discussion about ethical concerns in retaining DNA profiles and the issues involved when people use a database to search for close relatives. Students of forensic DNA analysis, forensic scientists, and members of the law enforcement and legal professions who want to know more about STR typing will find this book invaluable. - Includes a glossary with over 400 terms for quick reference of unfamiliar terms as well as an acronym guide to decipher the DNA dialect - Continues in the style of Forensic DNA Typing, 2e, with high-profile cases addressed in D.N.A.Boxes-- "Data, Notes & Applications" sections throughout - Ancillaries include: instructor manual Web site, with tailored set of 1000+ PowerPoint slides (including figures), links to online training websites and a test bank with key

Gravity Falls: Journal 3 Special Edition

Author : Alex Hirsch
Publisher : Disney Press
ISBN 13 : 9781368002509
Total Pages : 0 pages
Book Rating : 4.0/5 (25 download)

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Book Synopsis Gravity Falls: Journal 3 Special Edition by : Alex Hirsch

Download or read book Gravity Falls: Journal 3 Special Edition written by Alex Hirsch and published by Disney Press. This book was released on 2017-06-13 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Untie the string and unwrap the brown paper to reveal . . . Journal 3 Limited Edition! This 288-page book contains all of the content of the regular edition, plus all-new top-secret black light pages on real parchment; a cover with leather texture and shiny metallic pieces; a magnifying glass; a tassel bookmark; and removable photos and notes. This $150 limited edition will also include a signed note from the creator of Gravity Falls and co-writer of Journal 3, Alex Hirsch himself.

Gene Machine

Author : Venki Ramakrishnan
Publisher : Basic Books
ISBN 13 : 046509337X
Total Pages : 290 pages
Book Rating : 4.4/5 (65 download)

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Book Synopsis Gene Machine by : Venki Ramakrishnan

Download or read book Gene Machine written by Venki Ramakrishnan and published by Basic Books. This book was released on 2018-11-06 with total page 290 pages. Available in PDF, EPUB and Kindle. Book excerpt: A Nobel Prize-winning biologist tells the riveting story of his race to discover the inner workings of biology's most important molecule "Ramakrishnan's writing is so honest, lucid and engaging that I could not put this book down until I had read to the very end." -- Siddhartha Mukherjee, author of The Emperor of All Maladies and The Gene Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome -- an enormous molecular machine made up of a million atoms -- that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

Genome Stability

Author : Igor Kovalchuk
Publisher : Academic Press
ISBN 13 : 0323856802
Total Pages : 762 pages
Book Rating : 4.3/5 (238 download)

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Book Synopsis Genome Stability by : Igor Kovalchuk

Download or read book Genome Stability written by Igor Kovalchuk and published by Academic Press. This book was released on 2021-07-17 with total page 762 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. - A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects - Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability - Contains applications of genome instability research and outcomes for human disease - Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair

The Book of Mormon and DNA Research

Author : Daniel C. Peterson
Publisher : Neal A. Maxwell Institute for Religious Scholarship Brigham
ISBN 13 : 9780842527064
Total Pages : 287 pages
Book Rating : 4.5/5 (27 download)

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Book Synopsis The Book of Mormon and DNA Research by : Daniel C. Peterson

Download or read book The Book of Mormon and DNA Research written by Daniel C. Peterson and published by Neal A. Maxwell Institute for Religious Scholarship Brigham. This book was released on 2008-01-01 with total page 287 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Book of Mormon and DNA Research compiles all of the articles published by the Neal A. Maxwell Institute for Religious Scholarship on the subject of DNA. Some scientists have claimed that recent DNA findings "prove" the Book of Mormon false. The Maxwell Institute has gathered articles from top geneticists and DNA researchers that show the DNA evidence does not prove anything about the Book of Mormon.

The Cosmic Code (Book VI)

Author : Zecharia Sitchin
Publisher : Simon and Schuster
ISBN 13 : 1591439140
Total Pages : 257 pages
Book Rating : 4.5/5 (914 download)

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Book Synopsis The Cosmic Code (Book VI) by : Zecharia Sitchin

Download or read book The Cosmic Code (Book VI) written by Zecharia Sitchin and published by Simon and Schuster. This book was released on 2002-03-01 with total page 257 pages. Available in PDF, EPUB and Kindle. Book excerpt: Reveals Zecharia Sitchin's groundbreaking research into the code left behind by the creators of humanity. • Explains how the Anunnaki were not merely the mythical gods of the Sumerians, but rather the founders of human life on Earth. • Using Biblical and ancient Sumerian sources, explains how to decode these messages our star ancestors left behind. Daring to challenge our long-held beliefs about the origins of man, Zecharia Sitchin suggests that humans are not the children of God, but rather the children of the Anunnaki, an ancient race from the planet Nibiru. His revolutionary theories are supported by his intense scrutiny of not only ancient Sumerian texts but also stone structures all over the world. The similarities and astrological significance of these formations suggests that rather than looking for guidance from leaders here on Earth, humanity should instead look to the sky for answers. The Earth Chronicles deal with the history and prehistory of Earth and humankind. Each book in the series is based upon information written on clay tablets by the ancient civilizations of the Near East. For the first time, the entire Earth Chronicles series is now available in a hardcover collector's edition.

Obesity and Diabetes

Author : Anthony H. Barnett
Publisher : John Wiley & Sons
ISBN 13 : 0470011092
Total Pages : 324 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Obesity and Diabetes by : Anthony H. Barnett

Download or read book Obesity and Diabetes written by Anthony H. Barnett and published by John Wiley & Sons. This book was released on 2005-04-08 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: Obesity has become the most common chronic disease of the present day, with significant increases in prevalence in populations across the world and all age groups. This has resulted in a dramatic increase in obesity-related metabolic and cardiovascular complications, making it an important public health issue. Type 2 diabetes associated with obesity or 'diabesity' is today the most common form of type 2 diabetes. It is also associated with a number of other cardiovascular risk factors, which constitute the metabolic syndrome. Effective management of 'diabesity' is crucial to the reduction of morbidity and premature mortality due to cardiovascular disease. This book comprises chapters written by leading international experts on various aspects of obesity-related diabetes. As a practical reference guide, it is suitable for all professionals with an interest in this field. Emerging problems such as childhood 'diabesity' and the impact of obesity on polycystic ovary syndrome will be of interest not only to paediatricians and endocrinologists, but also to general practitioners and other healthcare professionals. The contemporary approach to the clinical assessment of obesity and its management in both primary and secondary care settings is also described.

Signature in the Cell

Author : Stephen C. Meyer
Publisher : Zondervan
ISBN 13 : 0061472786
Total Pages : 628 pages
Book Rating : 4.0/5 (614 download)

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Book Synopsis Signature in the Cell by : Stephen C. Meyer

Download or read book Signature in the Cell written by Stephen C. Meyer and published by Zondervan. This book was released on 2009-06-23 with total page 628 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book attempts to make a comprehensive, interdisciplinary case for a new view of the origin of life"--Prologue.

Molecular Evolution

Author : Roderick D.M. Page
Publisher : John Wiley & Sons
ISBN 13 : 1444313363
Total Pages : 352 pages
Book Rating : 4.4/5 (443 download)

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Book Synopsis Molecular Evolution by : Roderick D.M. Page

Download or read book Molecular Evolution written by Roderick D.M. Page and published by John Wiley & Sons. This book was released on 2009-07-14 with total page 352 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility.

Anatomy of Gene Regulation

Author : Panagiotis A. Tsonis
Publisher : Cambridge University Press
ISBN 13 : 9780521804745
Total Pages : 300 pages
Book Rating : 4.8/5 (47 download)

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Book Synopsis Anatomy of Gene Regulation by : Panagiotis A. Tsonis

Download or read book Anatomy of Gene Regulation written by Panagiotis A. Tsonis and published by Cambridge University Press. This book was released on 2003-01-13 with total page 300 pages. Available in PDF, EPUB and Kindle. Book excerpt: No longer simple line drawings on a page, molecular structures can now be viewed in full-figured glory, often in color and even with interactive possibilities. Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three-dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. Throughout, the text employs a discussion of genetics and structural mechanics. The concise and unique synthesis of information will offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states. This textbook and its accompanying web site are appropriate for both undergraduate and graduate students in genetics, molecular biology, structural biology, and biochemistry courses.

Sophie's World

Author : Jostein Gaarder
Publisher : Farrar, Straus and Giroux
ISBN 13 : 1466804270
Total Pages : 599 pages
Book Rating : 4.4/5 (668 download)

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Book Synopsis Sophie's World by : Jostein Gaarder

Download or read book Sophie's World written by Jostein Gaarder and published by Farrar, Straus and Giroux. This book was released on 2007-03-20 with total page 599 pages. Available in PDF, EPUB and Kindle. Book excerpt: A page-turning novel that is also an exploration of the great philosophical concepts of Western thought, Jostein Gaarder's Sophie's World has fired the imagination of readers all over the world, with more than twenty million copies in print. One day fourteen-year-old Sophie Amundsen comes home from school to find in her mailbox two notes, with one question on each: "Who are you?" and "Where does the world come from?" From that irresistible beginning, Sophie becomes obsessed with questions that take her far beyond what she knows of her Norwegian village. Through those letters, she enrolls in a kind of correspondence course, covering Socrates to Sartre, with a mysterious philosopher, while receiving letters addressed to another girl. Who is Hilde? And why does her mail keep turning up? To unravel this riddle, Sophie must use the philosophy she is learning—but the truth turns out to be far more complicated than she could have imagined.

RUNX Proteins in Development and Cancer

Author : Yoram Groner
Publisher : Springer
ISBN 13 : 9811032335
Total Pages : 518 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis RUNX Proteins in Development and Cancer by : Yoram Groner

Download or read book RUNX Proteins in Development and Cancer written by Yoram Groner and published by Springer. This book was released on 2017-03-15 with total page 518 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function in cell biology. Their documented roles in cell fate decisions include control of proliferation, differentiation, survival, senescence and autophagy. The pleiotropic effects of RUNX in development are mirrored in cancer, where RUNX genes can function as oncogenes that collaborate strongly with Myc family oncogenes or as tumour suppressor genes. In the latter role, they display hallmarks of both ‘gatekeepers’ that modulate p53 responses and ‘caretakers’ that protect the genome from DNA damage. Several chapters focus on the importance of these genes in leukemia research, where RUNX1 and CBFB are frequently affected by chromosomal translocations that generate fusion oncoproteins, while recent studies suggest wider roles for RUNX modulation in solid cancers. Moreover, RUNX genes are intimately involved in the development and regulation of the immune system, while emerging evidence suggests a role in innate immunity to infectious agents, including HIV. At the biochemical level, the RUNX family can serve as activators or repressors of transcription and as stable mediators of epigenetic memory through mitosis. Not surprisingly, RUNX activity is controlled at multiple levels, this includes miRNAs and a plethora of post-translational modifications. Several chapters highlight the interplay between the three mammalian RUNX genes, where cross-talk and partial functional redundancies are evident. Finally, structural analysis of the RUNX/CBFB interaction has led to the development of small molecule inhibitors that provide exciting new tools to decipher the roles of RUNX in development and as targets for therapy. This volume provides a compendium and reference source that will be of broad interest to cancer researchers, developmental biologists and immunologists.

Archaeology, Anthropology, and Interstellar Communication

Author : National Aeronautics Administration
Publisher : CreateSpace
ISBN 13 : 9781501081729
Total Pages : 332 pages
Book Rating : 4.0/5 (817 download)

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Book Synopsis Archaeology, Anthropology, and Interstellar Communication by : National Aeronautics Administration

Download or read book Archaeology, Anthropology, and Interstellar Communication written by National Aeronautics Administration and published by CreateSpace. This book was released on 2014-09-06 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: Addressing a field that has been dominated by astronomers, physicists, engineers, and computer scientists, the contributors to this collection raise questions that may have been overlooked by physical scientists about the ease of establishing meaningful communication with an extraterrestrial intelligence. These scholars are grappling with some of the enormous challenges that will face humanity if an information-rich signal emanating from another world is detected. By drawing on issues at the core of contemporary archaeology and anthropology, we can be much better prepared for contact with an extraterrestrial civilization, should that day ever come.