Photoionization and Photo-Induced Processes in Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 3527335102
Total Pages : 448 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Photoionization and Photo-Induced Processes in Mass Spectrometry by : Ralf Zimmermann

Download or read book Photoionization and Photo-Induced Processes in Mass Spectrometry written by Ralf Zimmermann and published by John Wiley & Sons. This book was released on 2021-07-06 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Provides comprehensive coverage of laser-induced ionization processes for mass spectrometry analysis Drawing on the expertise of the leading academic and industrial research groups involved in the development of photoionization methods for mass spectrometry, this reference for analytical scientists covers both the theory and current applications of photo-induced ionization processes. It places widely used techniques such as MALDI side by side with more specialist approaches such as REMPI and RIMS, and discusses leading edge developments in ultrashort laser pulse desorption, to give readers a complete picture of the state of the technology. Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications starts with a complete overview of the fundamentals of the technique, covering the basics of the gas phase ionization as well as those of laser desorption and ablation, pulse photoionization, and single particle ionization. Numerous application examples from different analytical fields are described that showcase the power and the wide scope of photo ionization in mass spectrometry. -The first general reference book on photoionization techniques for mass spectrometry -Examines technologies and applications of gas phase resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS) and gas phase resonance ionization mass spectrometry (RIMS) -Provides complete coverage of popular techniques like MALDI -Discusses the current and potential applications of each technology, focusing on process and environmental analysis Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications is an excellent book for spectroscopists, analytical chemists, photochemists, physical chemists, and laser specialists.

Solid Sample Analysis

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Publisher : Springer Science & Business Media
ISBN 13 : 3662037165
Total Pages : 442 pages
Book Rating : 4.6/5 (62 download)

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Book Synopsis Solid Sample Analysis by : Ulrich Kurfürst

Download or read book Solid Sample Analysis written by Ulrich Kurfürst and published by Springer Science & Business Media. This book was released on 2013-04-17 with total page 442 pages. Available in PDF, EPUB and Kindle. Book excerpt: The analysis of solid materials by introducing solid test sampies directly into the graphite furnace of an atomic absorption spectrometer must be regarded as a powerful analytical approach. Even if it is - of course - not the "ultimate method". After three decades of development, the instrumentation and the methodology are available to apply solid sampling successfully for the analysis of almost every material. Moreover, several tasks cannot be solved using other analytical methods as neatly as they can using direct solid sampling. The conventional methods work more or less satisfactorily, so why do we sug gest applying solid sampling much more extensively than it is today? To begin with, the features pointed out time and again should be named: Rapidity of the analytical procedure, low susceptibility to analyte loss or contamination, very smallquantities can be analyzed, and expenditure on instrumentation and per sonell is also low. These properties are examined and the necessary conditions are discussed (Chapter 1) as are the analytical tasks (Chapter 6) for which use of this method is advantageous. Other features that are often overlooked are just as important: The simplicity of the analytical procedures allows the analyst to main tain an intimate relationship with the original scientific task that has to be solved with the analysis. Furthermore, the considerable reduction of working place haz ards and pollution by avoiding the use of chemical reagents must nowadays be assessed as a feature as important as the others.

Ambient Ionization Mass Spectrometry

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Publisher : Royal Society of Chemistry
ISBN 13 : 1849739269
Total Pages : 528 pages
Book Rating : 4.8/5 (497 download)

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Book Synopsis Ambient Ionization Mass Spectrometry by : Marek Domin

Download or read book Ambient Ionization Mass Spectrometry written by Marek Domin and published by Royal Society of Chemistry. This book was released on 2014-11-25 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient ionization has emerged as one of the hottest and fastest growing topics in mass spectrometry enabling sample analysis with minimal sample preparation. Introducing the subject and explaining the basic concepts and terminology, this book will provide a comprehensive, unique treatise devoted to the subject. Written by acknowledged experts, there are full descriptions on how new ionization techniques work, with an overview of their strengths, weaknesses and applications. This title will bring the reader right up to date, with both applications and theory, and will be suitable as a tutorial text for those starting in the field from a variety of disciplines.

Measuring Elemental Impurities in Pharmaceuticals

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Publisher : CRC Press
ISBN 13 : 1351984403
Total Pages : 474 pages
Book Rating : 4.3/5 (519 download)

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Book Synopsis Measuring Elemental Impurities in Pharmaceuticals by : Robert Thomas

Download or read book Measuring Elemental Impurities in Pharmaceuticals written by Robert Thomas and published by CRC Press. This book was released on 2018-01-29 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent regulations on heavy metal testing have required the pharmaceutical industry to monitor a suite of elemental impurities in pharmaceutical raw materials, drug products and dietary supplements. These new directives s are described in the new United States Pharmacopeia (USP) Chapters , , and , together with Q3D, Step 4 guidelines for elemental impurities, drafted by the ICH (International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use), a consortium of global pharmaceutical associations, including the European Pharmacopeia (Ph.Eur.), the Japanese Pharmacopeia (JP) and the USP. This book provides a complete guide to the analytical methodology, instrumental techniques and sample preparation procedures used for measuring elemental impurities in pharmaceutical and nutraceutical materials. It offers readers the tools to better understand plasma spectrochemistry to optimize detection capability for the full suite of elemental PDE (Permitted Daily Exposure) levels in the various drug delivery categories. Other relevant information covered in the book includes: The complete guide to measuring elemental impurities in pharmaceutical and nutraceutical materials. Covers heavy metals testing in the pharmaceutical industry from an historical perspective. Gives an overview of current USP Chapters and and ICH Q3D Step 4 Guidelines. Explains the purpose of validation protocols used in Chapter , including how J-values are calculated Describes fundamental principles and practical capabilities of ICP-MS and ICP-OES. Offers guidelines about the optimum strategy for risk assessment Provides tips on how best to prepare and present your data for regulatory inspection. An indispensable resource, the fundamental principles and practical benefits of ICP-OES and ICP-MS are covered in a reader-friendly format that a novice, who is carrying out elemental impurities testing in the pharmaceutical and nutraceutical communities, will find easy to understand.

Mass Spectrometry Imaging in Food Analysis

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Publisher : CRC Press
ISBN 13 : 0429765304
Total Pages : 215 pages
Book Rating : 4.4/5 (297 download)

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Book Synopsis Mass Spectrometry Imaging in Food Analysis by : Leo M.L. Nollet

Download or read book Mass Spectrometry Imaging in Food Analysis written by Leo M.L. Nollet and published by CRC Press. This book was released on 2020-04-29 with total page 215 pages. Available in PDF, EPUB and Kindle. Book excerpt: Food contains various compounds and many technologies exist to analyze those molecules of interest. However, the analysis of the spatial distribution of those compounds using conventional technology, such as liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Mass spectrometry imaging (MSI) is a mass spectrometry technique to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte and so quantification is possible. Mass Spectrometry Imaging in Food Analysis, a volume in the Food Analysis and Properties Series, explains how the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) will be an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. It can be used to visualize the spatial distribution of biomolecules in foods. Features: Explains the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging in food analysis Describes how MALDI-MSI will be a useful technique for optical quality assurance. Shows how MALDI-MSI detects food contaminants and residues Covers the historical development of the technology While there are a multitude of books on mass spectrometry, none focus on food applications and thus this book is ideally suited to food scientists, food industry personnel engaged in product development, research institutions, and universities active in food analysis or chemical analysis. Also available in the Food Analysis and Properties Series: Food Aroma Evolution: During Food Processing, Cooking, and Aging, edited by Matteo Bordiga and Leo M.L. Nollet (ISBN: 9781138338241) Ambient Mass Spectroscopy Techniques in Food and the Environment, edited by Leo M.L. Nollet and Basil K. Munjanja (ISBN: 9781138505568) Hyperspectral Imaging Analysis and Applications for Food Quality, edited by N.C. Basantia, Leo M.L. Nollet, and Mohammed Kamruzzaman (ISBN: 9781138630796) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

Handbook of Green Analytical Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 0470972017
Total Pages : 569 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Handbook of Green Analytical Chemistry by : Miguel de la Guardia

Download or read book Handbook of Green Analytical Chemistry written by Miguel de la Guardia and published by John Wiley & Sons. This book was released on 2012-04-23 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: The emerging field of green analytical chemistry is concerned with the development of analytical procedures that minimize consumption of hazardous reagents and solvents, and maximize safety for operators and the environment. In recent years there have been significant developments in methodological and technological tools to prevent and reduce the deleterious effects of analytical activities; key strategies include recycling, replacement, reduction and detoxification of reagents and solvents. The Handbook of Green Analytical Chemistry provides a comprehensive overview of the present state and recent developments in green chemical analysis. A series of detailed chapters, written by international specialists in the field, discuss the fundamental principles of green analytical chemistry and present a catalogue of tools for developing environmentally friendly analytical techniques. Topics covered include: Concepts: Fundamental principles, education, laboratory experiments and publication in green analytical chemistry. The Analytical Process: Green sampling techniques and sample preparation, direct analysis of samples, green methods for capillary electrophoresis, chromatography, atomic spectroscopy, solid phase molecular spectroscopy, derivative molecular spectroscopy and electroanalytical methods. Strategies: Energy saving, automation, miniaturization and photocatalytic treatment of laboratory wastes. Fields of Application: Green bioanalytical chemistry, biodiagnostics, environmental analysis and industrial analysis. This advanced handbook is a practical resource for experienced analytical chemists who are interested in implementing green approaches in their work.

Mass Spectrometry Basics

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Publisher : CRC Press
ISBN 13 : 1420040340
Total Pages : 474 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Mass Spectrometry Basics by : Christopher G. Herbert

Download or read book Mass Spectrometry Basics written by Christopher G. Herbert and published by CRC Press. This book was released on 2002-06-26 with total page 474 pages. Available in PDF, EPUB and Kindle. Book excerpt: Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides

Time-Resolved Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 1118887344
Total Pages : 376 pages
Book Rating : 4.1/5 (188 download)

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Book Synopsis Time-Resolved Mass Spectrometry by : Pawel L. Urban

Download or read book Time-Resolved Mass Spectrometry written by Pawel L. Urban and published by John Wiley & Sons. This book was released on 2016-01-12 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time is an important factor in physical and natural sciences. It characterizes the progress of chemical and biochemical processes. Mass spectrometry provides the means to study molecular structures by detecting gas-phase ions with the unique mass-to-charge ratios. Time-resolved mass spectrometry (TRMS) allows one to differentiate between chemical states that can be observed sequentially at different time points. Real-time mass spectrometric monitoring enables recording data continuously with a specified temporal resolution. The TRMS approaches – introduced during the past few decades – have shown temporal resolutions ranging from hours down to microseconds and beyond. This text covers the key aspects of TRMS. It introduces ion sources, mass analyzers, and interfaces utilized in time-resolved measurements; discusses the influence of data acquisition and treatment; finally, it reviews most prominent applications of TRMS – in the studies of reaction kinetics and mechanism, physicochemical phenomena, protein structure dynamics, biocatalysis, and metabolic profiling. It will assist science and engineering students to gain a basic understanding of the TRMS concept, and to recognize its usefulness. In addition, it may benefit scientists who conduct molecular studies in the areas of chemistry, physics and biology.

Characterization of Solid Materials and Heterogeneous Catalysts

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Publisher : John Wiley & Sons
ISBN 13 : 3527645330
Total Pages : 1313 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Characterization of Solid Materials and Heterogeneous Catalysts by : Michel Che

Download or read book Characterization of Solid Materials and Heterogeneous Catalysts written by Michel Che and published by John Wiley & Sons. This book was released on 2012-04-16 with total page 1313 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume book provides an overview of physical techniques used to characterize the structure of solid materials, on the one hand, and to investigate the reactivity of their surface, on the other. Therefore this book is a must-have for anyone working in fields related to surface reactivity. Among the latter, and because of its most important industrial impact, catalysis has been used as the directing thread of the book. After the preface and a general introduction to physical techniques by M. Che and J.C. Vedrine, two overviews on physical techniques are presented by G. Ertl and Sir J.M. Thomas for investigating model catalysts and porous catalysts, respectively. The book is organized into four parts: Molecular/Local Spectroscopies, Macroscopic Techniques, Characterization of the Fluid Phase (Gas and/ or Liquid), and Advanced Characterization. Each chapter focuses upon the following important themes: overview of the technique, most important parameters to interpret the experimental data, practical details, applications of the technique, particularly during chemical processes, with its advantages and disadvantages, conclusions.

Direct Analysis in Real Time Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 3527341846
Total Pages : 370 pages
Book Rating : 4.5/5 (273 download)

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Book Synopsis Direct Analysis in Real Time Mass Spectrometry by : Yiyang Dong

Download or read book Direct Analysis in Real Time Mass Spectrometry written by Yiyang Dong and published by John Wiley & Sons. This book was released on 2018-04-09 with total page 370 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clear, comprehensive, and state of the art, the groundbreaking book on the emerging technology of direct analysis in real time mass spectrometry Written by a noted expert in the field, Direct Analysis in Real Time Mass Spectrometry offers a review of the background and the most recent developments in DART-MS. Invented in 2005, DART-MS offers a wide range of applications for solving numerous analytical problems in various environments, including food science, forensics, and clinical analysis. The text presents an introduction to the history of the technology and includes information on the theoretical background, for exampleon the ionization mechanism. Chapters on sampling and coupling to different types of mass spectrometers are followed by a comprehensive discussion of a broad range of applications. Unlike most other ionization methods, DART does not require laborious sample preparation, as ionization takes place directly on the sample surface. This makes the technique especially attractive for applications in forensics and food science. Comprehensive in scope, this vital text: -Sets the standard on an important and emerging ionization technique -Thoroughly discusses all the relevant aspects from instrumentation to applications -Helps in solving numerous analytical problems in various applications, for example food science, forensics, environmental and clinical analysis -Covers mechanisms, coupling to mass spectrometers, and includes information on challenges and disadvantages of the technique Academics, analytical chemists, pharmaceutical chemists, clinical chemists, forensic scientists, and others will find this illuminating text a must-have resource for understanding the most recent developments in the field.

Mass Spectrometry

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Publisher : Springer Science & Business Media
ISBN 13 : 3642107095
Total Pages : 773 pages
Book Rating : 4.6/5 (421 download)

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Book Synopsis Mass Spectrometry by : Jürgen H Gross

Download or read book Mass Spectrometry written by Jürgen H Gross and published by Springer Science & Business Media. This book was released on 2011-02-14 with total page 773 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book offers a balanced mixture of practice-oriented information and theoretical background as well as numerous references, clear illustrations, and useful data tables. Problems and solutions are accessible via a special website. This new edition has been completely revised and extended; it now includes three new chapters on tandem mass spectrometry, interfaces for sampling at atmospheric pressure, and inorganic mass spectrometry.

Handbook of Metrology

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Publisher : John Wiley & Sons
ISBN 13 : 3527406662
Total Pages : 747 pages
Book Rating : 4.5/5 (274 download)

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Book Synopsis Handbook of Metrology by : Michael Gläser

Download or read book Handbook of Metrology written by Michael Gläser and published by John Wiley & Sons. This book was released on 2010-06-08 with total page 747 pages. Available in PDF, EPUB and Kindle. Book excerpt: Metrology is the study of measurement. It includes all theoretical and practical aspects of measurement and may be divided into three subfields: Scientific or fundamental metrology concerns the establishment of measurement units, unit systems, development of new measurement methods, realization of measurement standards and the transfer of traceability from these standards to users in society. This handbook contains articles dealing with general topics of measurement and articles on particular subjects in mechanics and acoustics, electricity, optics, temperature, time and frequency, chemistry, medicine and particles. The contributions of the first part are sumamrized as follows. Introduction Units Fundamental Constants Fundamentals of Materials Measurement and Testing Measurement of Mass Desnity Measurement and Instrumentation of Flow Ultrasonics Measurement of Basic Electromagnetic Quantities Quantum Electrical Standards Metrology of Time and Frequency Temperature Measurement Metrology in Medicine

Laser Ablation and Desorption

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Publisher : Academic Press
ISBN 13 : 0080860206
Total Pages : 671 pages
Book Rating : 4.0/5 (88 download)

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Book Synopsis Laser Ablation and Desorption by :

Download or read book Laser Ablation and Desorption written by and published by Academic Press. This book was released on 1997-12-10 with total page 671 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume introduces the subject of laser ablation and desorption to scientists and engineers. It covers fundamental experimental and theoretical tools, models, and techniques, and introduces the most important applications. Clearly written and organized in a straightforward manner, Laser Ablation and Desorption lead the reader straight through the fundamentals of laser-surface interactions. Each chapter is self-contained and includes references to other chapters as necessary, so that readers may begin with the topic of greatest interest and follow the references to other aspects of the subject contained within the book.Key Features* Provides up-to-date information about one of the most active fields in physics today* Written and edited by major figures in the field of laser ablation and desorption* Represents the most comprehensive treatment of the state-of-the-art available

Ambient Mass Spectroscopy Techniques in Food and the Environment

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Publisher : CRC Press
ISBN 13 : 1351378481
Total Pages : 407 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Ambient Mass Spectroscopy Techniques in Food and the Environment by : Leo M.L. Nollet

Download or read book Ambient Mass Spectroscopy Techniques in Food and the Environment written by Leo M.L. Nollet and published by CRC Press. This book was released on 2019-01-30 with total page 407 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ambient mass spectrometry—that is the use of mass spec but in the atmospheric environment—has been widely employed in food and environmental analysis. Ambient Mass Spectroscopy Techniques in Food and the Environment presents the theoretical underpinnings of mass spectrometry, and the benefits and pitfalls of ambient mass spectrometry, as well as the latest developments of the technique, in the analysis of food and environmental parameters. It describes methods that enable the detection of surface materials like waxes, alkaloids, flavors, or pesticides by plainly exposing the corresponding items to the ionization region of the interface, without harm to samples. Features: Explains the theoretical aspects of ambient mass spectrometry Describes how to use ambient MS techniques for food safety, authenticity, and traceability screening Lists the benefits of ambient MS in analysis of food and environmental parameters Covers recent developments of ambient MS in analysis of food and environmental parameters The specialized work provides insight to professionals practicing in food and the environment, including food scientists, food engineers, food biotechnologists, chemical engineers, and those working in research labs, universities, and government regulatory agencies.

Lasers in Analytical Atomic Spectroscopy

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Publisher : John Wiley & Sons
ISBN 13 : 9780471186236
Total Pages : 292 pages
Book Rating : 4.1/5 (862 download)

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Book Synopsis Lasers in Analytical Atomic Spectroscopy by : Joseph Sneddon

Download or read book Lasers in Analytical Atomic Spectroscopy written by Joseph Sneddon and published by John Wiley & Sons. This book was released on 1996-12-27 with total page 292 pages. Available in PDF, EPUB and Kindle. Book excerpt: Die wichtigsten Möglichkeiten des Einsatzes von Lasern in der Atomspektroskopie - übersichtlich zusammengestellt und kritisch diskutiert! Diese erste Monographie zum Thema bringt Ihnen vielfältige Aspekte dieses noch jungen Gebietes nahe, von dem man sich eine stürmische Entwicklung im Verlauf der nächste 4-5 Jahre verspricht. Neben einer zügigen, mathematisch nicht überladenen Einführung in die Grundlagen der Atomspektroskopie und Lasertechnologie erfahren Sie von anerkannten Spezialisten Einzelheiten zur Atomfluoreszenzspektroskopie mit Laseranregung, Laserablation (Probenpräparation in ICP-MS und ICP-AES), zur laserinduzierten Emissionsspektrometrie (LIBS) und laserverstärkten Ionisationsspektrometrie (LEI).

Encyclopedia of Spectroscopy and Spectrometry

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Publisher : Academic Press
ISBN 13 : 0128032251
Total Pages : 3716 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Encyclopedia of Spectroscopy and Spectrometry by :

Download or read book Encyclopedia of Spectroscopy and Spectrometry written by and published by Academic Press. This book was released on 2016-09-22 with total page 3716 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry. Incorporates more than 150 color figures, 5,000 references, and 300 articles for a thorough examination of the field Highlights new research and promotes innovation in applied areas ranging from food science and forensics to biomedicine and health Presents a one-stop resource for quick access to answers and an in-depth examination of topics in the spectroscopy and spectrometry arenas

Liquid Chromatography Time-of-Flight Mass Spectrometry

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Publisher : John Wiley & Sons
ISBN 13 : 047042995X
Total Pages : 281 pages
Book Rating : 4.4/5 (74 download)

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Book Synopsis Liquid Chromatography Time-of-Flight Mass Spectrometry by : Imma Ferrer

Download or read book Liquid Chromatography Time-of-Flight Mass Spectrometry written by Imma Ferrer and published by John Wiley & Sons. This book was released on 2009-05-06 with total page 281 pages. Available in PDF, EPUB and Kindle. Book excerpt: Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.