Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases

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Publisher : John Wiley & Sons
ISBN 13 : 1119289211
Total Pages : 513 pages
Book Rating : 4.1/5 (192 download)

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Book Synopsis Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases by : Honghui Zhou

Download or read book Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune-Mediated Inflammatory Diseases written by Honghui Zhou and published by John Wiley & Sons. This book was released on 2019-02-18 with total page 513 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, distribution, metabolism and excretion (ADME) of therapeutic proteins as well as translational pharmacokinetic/pharmacodynamic (PK/PD) modeling for them. This comprehensive volume answers that need to be addressed. Featuring eighteen chapters from world-renowned experts and opinion leaders in pharmacology, translational medicine and immunology, editors Honghui Zhou and Diane Mould have curated a much-needed collection of research on the advanced applications of pharmacometrics and systems pharmacology to the development of biotherapeutics and individualized treatment strategies for the treatment of IMIDs. Authors discuss the pathophysiology of autoimmune diseases in addition to both theoretical and practical aspects of quantitative pharmacology for therapeutic proteins, current translational medicine research methodologies and novel thinking in treatment paradigm strategies for IMIDs. Other notable features include: • Contributions from well-known authors representing leading academic research centers, specialized contract research organizations and pharmaceutical industries whose pipelines include therapeutic proteins • Chapters on a wide range of topics (e.g., pathophysiology of autoimmune diseases, biomarkers in ulcerative colitis, model-based meta-analysis use in the development of therapeutic proteins) • Case studies of applying quantitative pharmacology approaches to guiding therapeutic protein drug development in IMIDs such as psoriasis, inflammatory bowel disease, multiple sclerosis and lupus Zhou and Mould’s timely contribution to the critical study of biopharmaceuticals is a valuable resource for any academic and industry researcher working in pharmacokinetics, pharmacology, biochemistry, or biotechnology as well as the many clinicians seeking the safest and most effective treatments for patients dealing with chronic immune disorders.

Evidence-Based Gastroenterology and Hepatology

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Publisher : John Wiley & Sons
ISBN 13 : 1405140127
Total Pages : 643 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Evidence-Based Gastroenterology and Hepatology by : John W. D. McDonald

Download or read book Evidence-Based Gastroenterology and Hepatology written by John W. D. McDonald and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 643 pages. Available in PDF, EPUB and Kindle. Book excerpt: Traditional textbooks in this field have emphasized the basic sciences of pathology, biochemistry and physiology. Evidence-based Gastroenterology and Hepatology covers all the major diseases of the gastrointestinal tract and liver, utilizing clinical epidemiology to present the strongest and most current evidence for interventions. This second edition is edited and written by leading gastroenterologists from around the world, each chapter summarizes the evidence so that better informed decisions will be made about which treatments to offer to patients. It provides practising Gastroenterologists and Surgeons with clear information regarding the diagnosis and treatment of pancreatic diseases, giving clear evidence and experience-based material that is immediately relevant to clinical practice. Also contains a list of recommended reading at the end of each chapter. Take a look at up to date information at www.evidbasedgastro.com

Cumulated Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 1292 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Cumulated Index Medicus by :

Download or read book Cumulated Index Medicus written by and published by . This book was released on 1974 with total page 1292 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Current Bibliographies in Medicine

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Publisher :
ISBN 13 :
Total Pages : 506 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Current Bibliographies in Medicine by :

Download or read book Current Bibliographies in Medicine written by and published by . This book was released on 1988 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Abridged Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 312 pages
Book Rating : 4.0/5 ( download)

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Book Synopsis Abridged Index Medicus by :

Download or read book Abridged Index Medicus written by and published by . This book was released on 1997 with total page 312 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Colonoscopy

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Publisher : John Wiley & Sons
ISBN 13 : 047098693X
Total Pages : 668 pages
Book Rating : 4.4/5 (79 download)

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Book Synopsis Colonoscopy by : Jerome D. Waye

Download or read book Colonoscopy written by Jerome D. Waye and published by John Wiley & Sons. This book was released on 2008-04-15 with total page 668 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Edition - Winner of 2004 BMA Medical Book Competitionin Gastroenterology A state-of-the-art reference guide covering all aspects ofthe performance, technical and clinical background tocolonoscopy The second edition of this prize winning book is written by someof the world’s foremost experts in the field of colonoscopyand colonic imaging. Every chapter has been updated and 5 newchapters have been added to include the latest information andadvances in the field of colonoscopy: Capsule Colonoscopy Narrow Band Imaging Confocal Endomicroscopy Endoscopic Submucosal Dissection in the Colon New Colonoscopes and Assist Devices Drawing on the vast experience of the authors it coversevery area of medicine that impacts on colonoscopy, includingvirtual colonography, pathology, techniques for pediatric and adultprocedures, and legal aspects concerning colonoscopy. The book is focused on patient care, and provides explanationson how to perform the procedure effectively and make the bestoutcome for your patients. It serves as a detailed manual ofprocedures, extensively illustrated with diagrams and photographsand there is an accompanying DVD with multiple demonstrations oftechnique. This is an invaluable compendium on all aspects of colonoscopy,suitable for use by every grade of practitioner world-wide and anessential reference book for allestablishments with an endoscopyfacility.

Index of Conference Proceedings

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Publisher :
ISBN 13 :
Total Pages : 870 pages
Book Rating : 4.F/5 ( download)

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Book Synopsis Index of Conference Proceedings by : British Library. Document Supply Centre

Download or read book Index of Conference Proceedings written by British Library. Document Supply Centre and published by . This book was released on 2001 with total page 870 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Index Medicus

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Publisher :
ISBN 13 :
Total Pages : 2432 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Index Medicus by :

Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2432 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Bariatric Endoscopy

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Publisher : Springer Science & Business Media
ISBN 13 : 1441917101
Total Pages : 244 pages
Book Rating : 4.4/5 (419 download)

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Book Synopsis Bariatric Endoscopy by : Christopher C. Thompson

Download or read book Bariatric Endoscopy written by Christopher C. Thompson and published by Springer Science & Business Media. This book was released on 2013-02-06 with total page 244 pages. Available in PDF, EPUB and Kindle. Book excerpt: To date, diet programs and medical therapies for the treatment of obesity have had limited success. Bariatric surgery, however, provides a means of effective weight loss for many of those with morbid obesity. Most of these weight loss procedures are performed with a variety of techniques that continue to evolve. Each technique is associated with unique challenges and complications and it is important for the clinician to be knowledgeable about the endoscopic management of these patients. Additionally, as endoscopic technology evolves it may offer more than just the diagnosis and treatment of complications. Endoscopic therapy may soon allow less invasive bariatric revision procedures as well as a variety of primary obesity therapies for various patient populations. Bariatric Endoscopy reviews the management of obesity, normal post-surgical anatomy, endoscopic and medical management of post-surgical complications, and future endoscopic therapies for obesity management. Organized into five sections, the volume covers an obesity overview, traditional therapy, endoscopy and the bariatric patient, medical management of post-surgical complications, and the future role of endoscopy in obesity management. Detailed illustrations are also provided for surgical procedures, complications and obesity management chapters. Authored by authorities in the field, Bariatric Endoscopy is an indispensible tool for the gastroenterologist or surgical endoscopist as they care for patients with complicated bariatric issues.

Pancreatitis

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Publisher : BoD – Books on Demand
ISBN 13 : 1839681497
Total Pages : 96 pages
Book Rating : 4.8/5 (396 download)

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Book Synopsis Pancreatitis by : Dmitry Garbuzenko

Download or read book Pancreatitis written by Dmitry Garbuzenko and published by BoD – Books on Demand. This book was released on 2019-12-11 with total page 96 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book "Pancreatitis" is devoted to the actual and, in some cases, controversial and unresolved problems associated with acute and chronic pancreatitis. The material presented in it will be of interest to anyone who considers pancreatology their specialty.

International Congress Calendar

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Publisher :
ISBN 13 :
Total Pages : 388 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis International Congress Calendar by :

Download or read book International Congress Calendar written by and published by . This book was released on 2004 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Novinky zahraniční literatury

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Publisher :
ISBN 13 :
Total Pages : 264 pages
Book Rating : 4.:/5 (31 download)

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Book Synopsis Novinky zahraniční literatury by :

Download or read book Novinky zahraniční literatury written by and published by . This book was released on 2003 with total page 264 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Integrating Therapeutic and Complementary Nutrition

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Publisher : CRC Press
ISBN 13 : 1420003410
Total Pages : 653 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Integrating Therapeutic and Complementary Nutrition by : Mary J. Marian

Download or read book Integrating Therapeutic and Complementary Nutrition written by Mary J. Marian and published by CRC Press. This book was released on 2006-07-20 with total page 653 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumers look to health professionals for guidance on how to integrate complementary and alternative (CAM) therapies into their lifestyles, yet most health care professionals are trained only in conventional practices. Integrating Therapeutic and Complementary Nutrition provides the scientific foundation necessary to understand CAM nutrition pract

Colitis-Associated Cancer

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Publisher : Springer
ISBN 13 : 4431555226
Total Pages : 151 pages
Book Rating : 4.4/5 (315 download)

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Book Synopsis Colitis-Associated Cancer by : Masato Kusunoki

Download or read book Colitis-Associated Cancer written by Masato Kusunoki and published by Springer. This book was released on 2015-10-01 with total page 151 pages. Available in PDF, EPUB and Kindle. Book excerpt: As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book

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Publisher : Elsevier Health Sciences
ISBN 13 : 0323550274
Total Pages : 5208 pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book by : John E. Bennett

Download or read book Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases E-Book written by John E. Bennett and published by Elsevier Health Sciences. This book was released on 2019-08-08 with total page 5208 pages. Available in PDF, EPUB and Kindle. Book excerpt: For four decades, physicians and other healthcare providers have trusted Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases to provide expert guidance on the diagnosis and treatment of these complex disorders. The 9th Edition continues the tradition of excellence with newly expanded chapters, increased global coverage, and regular updates to keep you at the forefront of this vitally important field. Meticulously updated by Drs. John E. Bennett, Raphael Dolin, and Martin J. Blaser, this comprehensive, two-volume masterwork puts the latest information on challenging infectious diseases at your fingertips. - Provides more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than any other infectious disease resource. - Features an increased focus on antibiotic stewardship; new antivirals for influenza, cytomegalovirus, hepatitis C, hepatitis B., and immunizations; and new recommendations for vaccination against infection with pneumococci, papillomaviruses, hepatitis A, and pertussis. - Covers newly recognized enteroviruses causing paralysis (E-A71, E-D68); emerging viral infections such as Ebola, Zika, Marburg, SARS, and MERS; and important updates on prevention and treatment of C. difficile infection, including new tests that diagnose or falsely over-diagnose infectious diseases. - Offers fully revised content on bacterial pathogenesis, antibiotic use and toxicity, the human microbiome and its effects on health and disease, immunological mechanisms and immunodeficiency, and probiotics and alternative approaches to treatment of infectious diseases. - Discusses up-to-date topics such as use of the new PCR panels for diagnosis of meningitis, diarrhea and pneumonia; current management of infected orthopedic implant infections; newly recognized infections transmitted by black-legged ticks in the USA: Borrelia miyamotoi and Powassan virus; infectious complications of new drugs for cancer; new drugs for resistant bacteria and mycobacteria; new guidelines for diagnosis and therapy of HIV infections; and new vaccines against herpes zoster, influenza, meningococci. - PPID continues its tradition of including leading experts from a truly global community, including authors from Australia, Canada and countries in Europe, Asia, and South America. - Includes regular updates online for the life of the edition. - Features more than 1,500 high-quality, full-color photographs—with hundreds new to this edition. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices.

Recent Advances in Liver Diseases and Surgery

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Publisher : BoD – Books on Demand
ISBN 13 : 9535121936
Total Pages : 332 pages
Book Rating : 4.5/5 (351 download)

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Book Synopsis Recent Advances in Liver Diseases and Surgery by : Hesham Abdeldayem

Download or read book Recent Advances in Liver Diseases and Surgery written by Hesham Abdeldayem and published by BoD – Books on Demand. This book was released on 2015-10-28 with total page 332 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents the most recent advances in the field of liver diseases and surgery, including the remarkable advances in Hepatitis C therapy, liver tumors, injuries, cysts, resections, transplantation, and preoperative management of patients with liver diseases. The editors are the dean and vice deans of the National Liver Institute, Menoufia University, a dedicated international center of excellence and a leading medical institution in the Middle East for the diagnosis and management of liver diseases and advanced training and research in hepatobiliary sciences. The authors are leading experts from four continents across the globe (North America, Europe, Asia, and Africa). In other words, the book team reflects an international dream team of experts in the area of liver diseases.

Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455748013
Total Pages : 5094 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases by : John E. Bennett, MD, MACP

Download or read book Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases written by John E. Bennett, MD, MACP and published by Elsevier Health Sciences. This book was released on 2014-08-28 with total page 5094 pages. Available in PDF, EPUB and Kindle. Book excerpt: After thirty five years, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. John E. Bennett and Raphael Dolin along with new editorial team member Dr. Martin Blaser have meticulously updated this latest edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 8th Edition helps you identify and treat whatever infectious disease you see. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you'll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.