Diffusion And Use Of Genomic Innovations In Health And Medicine

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Diffusion and Use of Genomic Innovations in Health and Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309178312
Total Pages : 116 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Diffusion and Use of Genomic Innovations in Health and Medicine by : Institute of Medicine

Download or read book Diffusion and Use of Genomic Innovations in Health and Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2008-06-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions. Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.

Diffusion and Use of Genomic Innovations in Health and Medicine

Author : Roundtable on Translating Genomic-Based Research for Health
Publisher :
ISBN 13 : 9780309384070
Total Pages : 116 pages
Book Rating : 4.3/5 (84 download)

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Book Synopsis Diffusion and Use of Genomic Innovations in Health and Medicine by : Roundtable on Translating Genomic-Based Research for Health

Download or read book Diffusion and Use of Genomic Innovations in Health and Medicine written by Roundtable on Translating Genomic-Based Research for Health and published by . This book was released on 2008-06-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions. Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.

Diffusion and Use of Genomic Innovations in Health and Medicine

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309116767
Total Pages : 116 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Diffusion and Use of Genomic Innovations in Health and Medicine by : Institute of Medicine

Download or read book Diffusion and Use of Genomic Innovations in Health and Medicine written by Institute of Medicine and published by National Academies Press. This book was released on 2008-07-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions. Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.

Innovations in Service Delivery in the Age of Genomics

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309177588
Total Pages : 81 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Innovations in Service Delivery in the Age of Genomics by : Institute of Medicine

Download or read book Innovations in Service Delivery in the Age of Genomics written by Institute of Medicine and published by National Academies Press. This book was released on 2009-05-11 with total page 81 pages. Available in PDF, EPUB and Kindle. Book excerpt: New discoveries in genomics-that is, the study of the entire human genome-are changing how we diagnose and treat diseases. As the trend shifts from genetic testing largely being undertaken for rare genetic disorders to, increasingly, individuals being screened for common diseases, general practitioners, pediatricians, obstetricians/gynecologists, and other providers need to be knowledgeable about and comfortable using genetic information to improve their patients' health. To address these changes, the Roundtable on Translating Genomic-Based Research for Health held the public workshop "Innovations in Service Delivery in the Age of Genomics" on July 27, 2008.

Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309147417
Total Pages : 103 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health by : Institute of Medicine

Download or read book Systems for Research and Evaluation for Translating Genome-Based Discoveries for Health written by Institute of Medicine and published by National Academies Press. This book was released on 2009-11-10 with total page 103 pages. Available in PDF, EPUB and Kindle. Book excerpt: With the advent of genome-wide association studies, numerous associations between specific gene loci and complex diseases have been identified-for breast cancer, coronary artery disease, and asthma, for example. This rapidly advancing field of genomics has stirred great interest in "personalized" health care from both the public and private sectors. The hope is that using genomic information in clinical care will lead to reduced health care costs and improved health outcomes as therapies are tailored to the genetic susceptibilities of patients. A variety of genetically based health care innovations have already reached the marketplace, but information about the clinical use of these treatments and diagnostics is limited. Currently data do not provide information about how a genomic test impacts clinical care and patient health outcomes-other approaches are needed to garner such information. This volume summarizes a workshop to address central questions related to the development of systems to evaluate clinical use of health care innovations that stem from genome-based research: What are the practical realities of creating such systems? What different models could be used? What are the strengths and weaknesses of each model? How effectively can such systems address questions about health outcomes?

Genomic Medicine Skills and Competencies

Author : Dhavendra Kumar
Publisher : Academic Press
ISBN 13 : 0323985637
Total Pages : 166 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Genomic Medicine Skills and Competencies by : Dhavendra Kumar

Download or read book Genomic Medicine Skills and Competencies written by Dhavendra Kumar and published by Academic Press. This book was released on 2022-06-10 with total page 166 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genomic Medicine Skills and Competencies discusses core and practical aspects of genetic and genomic education and training for medical field. Many aspects of genomic applications in science, biotechnology, clinical medicine and healthcare require core and specialist knowledge, skills development and competencies for carrying out diverse tasks. Several knowledge-based courses and opportunities for skills and competencies development and assessment are now available and the main required subjects are discussed in this volume. The book focuses on all major aspects of genetic and genomic education training that are currently offered and evaluated and is a valuable resource for researchers, clinicians, physicians, nurses, genetic counselors, bioinformatics technicians, and other professionals who are interested in learning more about such promising field. Illustrates the need for acquiring and/or enhancing skills and competencies keeping up with the new advances and expanding scientific and technical knowledge in genome sciences as applied to the practice of clinical genomic and precision medicine Focuses on the professional and specific needs of medical and healthcare professionals practicing (or planning to practice) genomic medicine and health genomics Discusses the impact of effective genomic education and training for delivering the advances and new knowledge in the field of genome sciences and technologies that have spanned as a result of the COVID-19 pandemic in preparedness to what is next

Promoting Access to Medical Technologies and Innovation - Intersections between Public Health, Intellectual Property and Trade

Author : World Intellectual Property Organization
Publisher : WIPO
ISBN 13 : 9280523082
Total Pages : 259 pages
Book Rating : 4.2/5 (85 download)

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Book Synopsis Promoting Access to Medical Technologies and Innovation - Intersections between Public Health, Intellectual Property and Trade by : World Intellectual Property Organization

Download or read book Promoting Access to Medical Technologies and Innovation - Intersections between Public Health, Intellectual Property and Trade written by World Intellectual Property Organization and published by WIPO. This book was released on 2013 with total page 259 pages. Available in PDF, EPUB and Kindle. Book excerpt: This study has emerged from an ongoing program of trilateral cooperation between WHO, WTO and WIPO. It responds to an increasing demand, particularly in developing countries, for strengthened capacity for informed policy-making in areas of intersection between health, trade and IP, focusing on access to and innovation of medicines and other medical technologies.

Exploring the Current Landscape of Consumer Genomics

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309673038
Total Pages : 113 pages
Book Rating : 4.3/5 (96 download)

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Book Synopsis Exploring the Current Landscape of Consumer Genomics by : National Academies of Sciences, Engineering, and Medicine

Download or read book Exploring the Current Landscape of Consumer Genomics written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2020-08-23 with total page 113 pages. Available in PDF, EPUB and Kindle. Book excerpt: Consumer genomics, encompassing both direct-to-consumer applications (i.e., genetic testing that is accessed by a consumer directly from a commercial company apart from a health care provider) and consumer-driven genetic testing (i.e., genetic testing ordered by a health care provider in response to an informed patient request), has evolved considerably over the past decade, moving from more personal utility-focused applications outside of traditional health care to interfacing with clinical care in nontraditional ways. As consumer genomics has increasingly intersected with clinical applications, discussions have arisen around the need to demonstrate clinical and analytical validity and clinical utility due to the potential for misinterpretation by consumers. Clinical readiness and interest for this information have presented educational and training challenges for providers. At the same time, consumer genomics has emerged as a potentially innovative mechanism for thinking about health literacy and engaging participants in their health and health care. To explore the current landscape of consumer genomics and the implications for how genetic test information is used or may be used in research and clinical care, the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted a public workshop on October 29, 2019, in Washington, DC. Discussions included such topics as the diversity of participant populations, the impact of consumer genomics on health literacy and engagement, knowledge gaps related to the use of consumer genomics in clinical care, and regulatory and health policy issues such as data privacy and security. A broad array of stakeholders took part in the workshop, including genomics and consumer genomics experts, epidemiologists, health disparities researchers, clinicians, users of consumer genomics research applications, representatives from patient advocacy groups, payers, bioethicists, regulators, and policy makers. This publication summarizes the presentations and discussion of the workshop.

Informing the Future

Author : Institute of Medicine
Publisher : National Academies Press
ISBN 13 : 0309215366
Total Pages : 203 pages
Book Rating : 4.3/5 (92 download)

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Book Synopsis Informing the Future by : Institute of Medicine

Download or read book Informing the Future written by Institute of Medicine and published by National Academies Press. This book was released on 2011-10-12 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This report illustrates the work of IOM committees in selected, major areas in recent years, followed by a description of IOM's convening and collaborative activities and fellowship programs. The last section provides a comprehensive bibliography of IOM reports published since 2007.

Human Genome Epidemiology, 2nd Edition

Author : Muin Khoury
Publisher : Oxford University Press
ISBN 13 : 0195398440
Total Pages : 701 pages
Book Rating : 4.1/5 (953 download)

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Book Synopsis Human Genome Epidemiology, 2nd Edition by : Muin Khoury

Download or read book Human Genome Epidemiology, 2nd Edition written by Muin Khoury and published by Oxford University Press. This book was released on 2010-01-20 with total page 701 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text describes the role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. It provides a foundation that should help researchers, policy makers and practitioners integrate genomics into medical and public health practice.

Principles of Pharmacogenetics and Pharmacogenomics

Author : Russ B. Altman
Publisher : Cambridge University Press
ISBN 13 : 1107377471
Total Pages : 283 pages
Book Rating : 4.1/5 (73 download)

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Book Synopsis Principles of Pharmacogenetics and Pharmacogenomics by : Russ B. Altman

Download or read book Principles of Pharmacogenetics and Pharmacogenomics written by Russ B. Altman and published by Cambridge University Press. This book was released on 2012-01-23 with total page 283 pages. Available in PDF, EPUB and Kindle. Book excerpt: The study of pharmacogenetics and pharmacogenomics focuses on how our genes and complex gene systems influence our response to drugs. Recent progress in clinical therapeutics has led to the discovery of new biomarkers that make it technically easier to identify groups of patients which are more or less likely to respond to individual therapies. The aim is to improve personalised medicine - not simply to prescribe the right medicine, but to deliver the right drug at the right dose at the right time. This textbook brings together leading experts to discuss the latest information on how human genetics impacts drug response phenotypes. It presents not only the basic principles of pharmacogenetics, but also clinically valuable examples that cover a broad range of specialties and therapeutic areas. This textbook is an invaluable introduction to pharmacogenetics and pharmacogenomics for health care professionals, medical students, pharmacy students, graduate students and researchers in the biosciences.

Human Genome Epidemiology, 2nd Edition

Author : Muin Khoury
Publisher : Oxford University Press
ISBN 13 : 9780199749348
Total Pages : 704 pages
Book Rating : 4.7/5 (493 download)

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Book Synopsis Human Genome Epidemiology, 2nd Edition by : Muin Khoury

Download or read book Human Genome Epidemiology, 2nd Edition written by Muin Khoury and published by Oxford University Press. This book was released on 2010-01-20 with total page 704 pages. Available in PDF, EPUB and Kindle. Book excerpt: The first edition of Human Genome Epidemiology, published in 2004, discussed how the epidemiologic approach provides an important scientific foundation for studying the continuum from gene discovery to the development, applications and evaluation of human genome information in improving health and preventing disease. Since that time, advances in human genomics have continued to occur at a breathtaking pace. With contributions from leaders in the field from around the world, this new edition is a fully updated look at the ways in which genetic factors in common diseases are studied. Methodologic developments in collection, analysis and synthesis of data, as well as issues surrounding specific applications of human genomic information for medicine and public health are all discussed. In addition, the book focuses on practical applications of human genome variation in clinical practice and disease prevention. Students, clinicians, public health professionals and policy makers will find the book a useful tool for understanding the rapidly evolving methods of the discovery and use of genetic information in medicine and public health in the 21st century.

FDA in the Twenty-First Century

Author : Holly Fernandez Lynch
Publisher : Columbia University Press
ISBN 13 : 0231540078
Total Pages : 499 pages
Book Rating : 4.2/5 (315 download)

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Book Synopsis FDA in the Twenty-First Century by : Holly Fernandez Lynch

Download or read book FDA in the Twenty-First Century written by Holly Fernandez Lynch and published by Columbia University Press. This book was released on 2015-09-08 with total page 499 pages. Available in PDF, EPUB and Kindle. Book excerpt: In its decades-long effort to assure the safety, efficacy, and security of medicines and other products, the Food and Drug Administration has struggled with issues of funding, proper associations with industry, and the balance between consumer choice and consumer protection. Today, these challenges are compounded by the pressures of globalization, the introduction of novel technologies, and fast-evolving threats to public health. With essays by leading scholars and government and private-industry experts, FDA in the Twenty-First Century addresses perennial and new problems and the improvements the agency can make to better serve the public good. The collection features essays on effective regulation in an era of globalization, consumer empowerment, and comparative effectiveness, as well as questions of data transparency, conflicts of interest, industry responsibility, and innovation policy, all with an emphasis on pharmaceuticals. The book also intervenes in the debate over off-label drug marketing and the proper role of the FDA before and after a drug goes on the market. Dealing honestly and thoroughly with the FDA's successes and failures, these essays rethink the structure, function, and future of the agency and the effect policy innovations may have on regulatory institutions abroad.

Applying an Implementation Science Approach to Genomic Medicine

Author : National Academies of Sciences, Engineering, and Medicine
Publisher : National Academies Press
ISBN 13 : 0309437792
Total Pages : 137 pages
Book Rating : 4.3/5 (94 download)

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Book Synopsis Applying an Implementation Science Approach to Genomic Medicine by : National Academies of Sciences, Engineering, and Medicine

Download or read book Applying an Implementation Science Approach to Genomic Medicine written by National Academies of Sciences, Engineering, and Medicine and published by National Academies Press. This book was released on 2016-07-06 with total page 137 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although it is becoming increasingly more common for clinicians to use genomic data in their practices for disease prevention, diagnosis, and treatment, the process of integrating genomic data into the practice of medicine has been a slow and challenging one. Some of the major barriers impeding the incorporation of new genomic technology into clinical practice are: the difficulty of changing routine medical practices to account for the use of genetic testing, the limited knowledge of patients and providers about genomic medicine, assessing sufficient evidence to support the use of genetic tests, privacy and data security issues, and uncertainty about reimbursement. The field of implementation science may be able to provide insights concerning efficient ways to incorporate genomic applications into routine clinical practice. The focus of implementation science studies is to identify integration bottlenecks and optimal approaches for a given setting and ultimately to promote the up-take of research findings. To explore the potential of implementation science to improve the integration of genomics into medicine, the National Academies of Sciences, Engineering, and Medicine held a workshop in Washington, DC, in November 2015. Participants explored the challenges and opportunities of integrating genomic advances into the clinic through the lens of implementation science. This report summarizes the presentations and discussions from the workshop.

Economic Evaluation in Genomic Medicine

Author : Vasilios Fragoulakis
Publisher : Academic Press
ISBN 13 : 0128016116
Total Pages : 174 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Economic Evaluation in Genomic Medicine by : Vasilios Fragoulakis

Download or read book Economic Evaluation in Genomic Medicine written by Vasilios Fragoulakis and published by Academic Press. This book was released on 2015-03-20 with total page 174 pages. Available in PDF, EPUB and Kindle. Book excerpt: Economic Evaluation in Genomic Medicine introduces health economics and economic evaluation to genomic clinicians and researchers, while also introducing the topic to health economists. Each chapter includes an executive summary, questions, and case studies, along with supplementary online materials, including process guides, maps, flow charts, diagrams, and economic evaluation spreadsheets to enhance the learning process. The text can easily be used as course material for related graduate and undergraduate courses, providing a succinct overview of the existing, state-of-the-art application of economic evaluation to genomic healthcare and precision medicine. Interrelates economic evaluation and genomic medicine Instructs healthcare professionals and bioscientists about economic evaluation in genomic medicine Teaches health economists about application of economic evaluation in genomic medicine Introduces health economics and economic evaluation to clinicians and researchers involved in genomics Includes process guides, maps, flow charts and diagrams

Redefining Health Care

Author : Michael E. Porter
Publisher : Harvard Business Press
ISBN 13 : 1422133362
Total Pages : 540 pages
Book Rating : 4.4/5 (221 download)

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Book Synopsis Redefining Health Care by : Michael E. Porter

Download or read book Redefining Health Care written by Michael E. Porter and published by Harvard Business Press. This book was released on 2006-04-24 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: The U.S. health care system is in crisis. At stake are the quality of care for millions of Americans and the financial well-being of individuals and employers squeezed by skyrocketing premiums—not to mention the stability of state and federal government budgets. In Redefining Health Care, internationally renowned strategy expert Michael Porter and innovation expert Elizabeth Teisberg reveal the underlying—and largely overlooked—causes of the problem, and provide a powerful prescription for change. The authors argue that competition currently takes place at the wrong level—among health plans, networks, and hospitals—rather than where it matters most, in the diagnosis, treatment, and prevention of specific health conditions. Participants in the system accumulate bargaining power and shift costs in a zero-sum competition, rather than creating value for patients. Based on an exhaustive study of the U.S. health care system, Redefining Health Care lays out a breakthrough framework for redefining the way competition in health care delivery takes place—and unleashing stunning improvements in quality and efficiency. With specific recommendations for hospitals, doctors, health plans, employers, and policy makers, this book shows how to move health care toward positive-sum competition that delivers lasting benefits for all.

Diffusion of Innovations, 5th Edition

Author : Everett M. Rogers
Publisher : Simon and Schuster
ISBN 13 : 0743258231
Total Pages : 576 pages
Book Rating : 4.7/5 (432 download)

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Book Synopsis Diffusion of Innovations, 5th Edition by : Everett M. Rogers

Download or read book Diffusion of Innovations, 5th Edition written by Everett M. Rogers and published by Simon and Schuster. This book was released on 2003-08-16 with total page 576 pages. Available in PDF, EPUB and Kindle. Book excerpt: Now in its fifth edition, Diffusion of Innovations is a classic work on the spread of new ideas. In this renowned book, Everett M. Rogers, professor and chair of the Department of Communication & Journalism at the University of New Mexico, explains how new ideas spread via communication channels over time. Such innovations are initially perceived as uncertain and even risky. To overcome this uncertainty, most people seek out others like themselves who have already adopted the new idea. Thus the diffusion process consists of a few individuals who first adopt an innovation, then spread the word among their circle of acquaintances—a process which typically takes months or years. But there are exceptions: use of the Internet in the 1990s, for example, may have spread more rapidly than any other innovation in the history of humankind. Furthermore, the Internet is changing the very nature of diffusion by decreasing the importance of physical distance between people. The fifth edition addresses the spread of the Internet, and how it has transformed the way human beings communicate and adopt new ideas.