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Development Of An Akata Based Bacterial Artificial Chromosome
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Book Synopsis Development of an Akata-based Bacterial Artificial Chromosome by : Lavon Paongo Tonga
Download or read book Development of an Akata-based Bacterial Artificial Chromosome written by Lavon Paongo Tonga and published by . This book was released on 2006 with total page 104 pages. Available in PDF, EPUB and Kindle. Book excerpt: Genetic mutagenesis of individual genes in context of the complete Epstein-Barr virus genome is essential to understanding function of proteins. Past strategies for deriving a mutant within EBV have been to disrupt a gene with a cassette encoding for antibiotic resistance flanked with sequence surrounding the targeted gene. The cassette is transfected into virus-carrying cells and positive selection is applied to select for a genome in which homologous recombination with flanking sequence has occurred. Although this method has met with success, it has limitations. It is time consuming, since a successful insertion of the cassette relies on a rare recombination event in the eukaryotic cell, and it allows only a narrow range of mutations to be made. Several herpesviruses have been cloned as bacterial artificial chromosomes (BAC) where a mini-F' plasmid is cloned into the viral genome so that it can be propagated in both eukaryotic and prokaryotic cells. Standard bacterial genetics can then be applied to the whole viral genome in prokaryotic cells prior to transferring it into eukaryotic cells for production of mutant progeny.
Book Synopsis Bacterial Artificial Chromosomes by : Shaying Zhao
Download or read book Bacterial Artificial Chromosomes written by Shaying Zhao and published by Springer Science & Business Media. This book was released on 2008-02-03 with total page 333 pages. Available in PDF, EPUB and Kindle. Book excerpt: Several developmental and historical threads are woven and displayed in these two volumes of Bacterial Artificial Chromosomes, the first on Library Construction, Physical Mapping, and Sequencing, and the second on Fu- tional Studies. The use of large-insert clone libraries is the unifying feature, with many diverse contributions. The editors have had quite distinct roles. Shaying Zhao has managed several BAC end-sequencing projects. Marvin Stodolsky during 1970–1980 contributed to the elucidation of the natural b- teriophage/prophage P1 vector system. Later, he became a member of the Genome Task Group of the Department of Energy (DOE), through which s- port flowed for most clone library resources of the Human Genome Program (HGP). Some important historical contributions are not represented in this volume. This preface in part serves to mention these contributions and also briefly surveys historical developments. Leon Rosner (deceased) contributed substantially in developing a PAC library for drosophila that utilized a PI virion-based encapsidation and tra- fection process. This library served prominently in the Drosophila Genome Project collaboration. PACs proved easy to purify so that they substantially replaced the YACs used earlier. Much of the early automation for massive clone picking and processing was developed at the collaborating Lawrence Berkeley National Laboratory. However, the P1 virion encapsidation system itself was too fastidious, and P1 virion-based methods did not gain popularity in other genome projects.
Book Synopsis Bacterial Artificial Chromosomes by : Pradeep Chatterjee
Download or read book Bacterial Artificial Chromosomes written by Pradeep Chatterjee and published by BoD – Books on Demand. This book was released on 2011-11-25 with total page 152 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book focuses on the numerous applications of Bacterial Artificial Chromosomes (BACs) in a variety of studies. The topics reviewed range from using BAC libraries as resources for marsupial and monotreme gene mapping and comparative genomic studies, to using BACs as vehicles for maintaining the large infectious DNA genomes of viruses. The large size of the insert DNA in BACs and the ease of engineering mutations in that DNA within the bacterial host, allowed manipulating the BAC-viral DNA of Varicella-Zoster Virus. Other reviews include the maintenance and suitable expression of foreign genes from a Baculovirus genome, including protein complexes, from the BAC-viral DNA and generating vaccines from BAC-viral DNA genomes of Marek's disease virus. Production of multi-purpose BAC clones in the novel Bacillus subtilis host is described, along with chapters that illustrate the use of BAC transgenic animals to address important issues of gene regulation in vertebrates, such as functionally identifying novel cis-acting distal gene regulatory sequences.
Book Synopsis Development of Targeted Bacterial Artificial Chromosome Cloning Techniques by : Kate Willars
Download or read book Development of Targeted Bacterial Artificial Chromosome Cloning Techniques written by Kate Willars and published by . This book was released on 2002 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Bacterial Artificial Chromosome-Based Experimental Strategies in the Field of Developmental Neuroscience by : Youhei W. Terakawa
Download or read book Bacterial Artificial Chromosome-Based Experimental Strategies in the Field of Developmental Neuroscience written by Youhei W. Terakawa and published by . This book was released on 2011 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Bacterial Artificial Chromosome-Based Experimental Strategies in the Field of Developmental Neuroscience.
Book Synopsis Dissertation Abstracts International by :
Download or read book Dissertation Abstracts International written by and published by . This book was released on 2007 with total page 924 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Download or read book Index Medicus written by and published by . This book was released on 2004 with total page 2520 pages. Available in PDF, EPUB and Kindle. Book excerpt: Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Book Synopsis Insights in virology: 2021 by : Chunfu Zheng
Download or read book Insights in virology: 2021 written by Chunfu Zheng and published by Frontiers Media SA. This book was released on 2023-04-28 with total page 373 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Sleep Disorders and Sleep Deprivation by : Institute of Medicine
Download or read book Sleep Disorders and Sleep Deprivation written by Institute of Medicine and published by National Academies Press. This book was released on 2006-10-13 with total page 425 pages. Available in PDF, EPUB and Kindle. Book excerpt: Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.
Book Synopsis Liposome Technology by : Gregory Gregoriadis
Download or read book Liposome Technology written by Gregory Gregoriadis and published by CRC Press. This book was released on 2016-04-19 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liposome Technology, Volume I: Liposome Preparation and Related Techniques, Third Edition, is a thoroughly updated and expanded new edition of a classic text in the field. Including step-by-step technical details, Volume I illustrates numerous methods for liposome preparation and auxiliary techniques necessary for the stabilization and characteriza
Book Synopsis AIDS-Associated Viral Oncogenesis by : Craig Meyers
Download or read book AIDS-Associated Viral Oncogenesis written by Craig Meyers and published by Springer Science & Business Media. This book was released on 2007-05-04 with total page 274 pages. Available in PDF, EPUB and Kindle. Book excerpt: One of the most important aspects of AIDS is the loss of protective immune function in the infected host which leads to increased prevalence of opportunistic infections and cancers. This book specifically addresses viral-induced human cancers associated with AIDS and observed in the AIDS population. It addresses the specific treatment required in this special population and the molecular biology of the causative viral agents.
Book Synopsis Epstein Barr Virus Volume 1 by : Christian Münz
Download or read book Epstein Barr Virus Volume 1 written by Christian Münz and published by Springer. This book was released on 2015-10-12 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: Epstein Barr virus (EBV) was discovered as the first human tumor virus around 50 years ago. Since its discovery in Burkitt’s lymphoma it has been associated with various other malignancies, infectious mononucleosis and even autoimmune diseases. The two book volumes on EBV summarize the first 50 years of research on this tumor virus, starting with historical perspectives on discovery, oncogenicity and immune control, reviewing the role that the virus plays in the various associated diseases and concluding with a discussion on how the immune system keeps persistent EBV infection under control in healthy EBV carriers and can be used to treat EBV associated diseases. The respective 32 chapters are written by international experts from three continents for health care providers, biomedical researchers and patients that are affected by EBV. The assembled knowledge should help to understand EBV associated diseases better and to develop EBV specific vaccination in the near future.
Book Synopsis Pediatric Lymphomas by : Howard J. Weinstein
Download or read book Pediatric Lymphomas written by Howard J. Weinstein and published by Springer Science & Business Media. This book was released on 2007-01-20 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive textbook of Hodgkin's and non-Hodgkin's lymphomas written by leaders in the field of childhood lymphomas. It includes clinical, pathologic and molecular biology of each subtype of lymphoma. The pathology chapters are comprehensive and include excellent photographs. The book is at the level of subspecialists in pediatric hematology and oncology, radiation oncology, pediatric surgery and hematopathology.
Book Synopsis Latency Strategies of Herpesviruses by : Janos Minarovits
Download or read book Latency Strategies of Herpesviruses written by Janos Minarovits and published by Springer Science & Business Media. This book was released on 2006-12-13 with total page 309 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume provides an overview of the latency strategies developed during the estimated 200,000 year-long coevolution of Alpha-, Beta- and Gammaherpesvirinae and their host species. While the main emphasis is on herpesviruses infecting humans, relevant cases if herpesviruses infecting animals are covered as well. Special emphasis is given to results on molecular mechanisms regulating latent promoters of herpesvirus genomes and signals and molecular pathways resulting in reactivation of latent viral genomes.
Book Synopsis Human Herpesviruses by : Yasushi Kawaguchi
Download or read book Human Herpesviruses written by Yasushi Kawaguchi and published by Springer. This book was released on 2018-06-12 with total page 498 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book introduces and reviews several topics for each human herpesvirus. One of the most important features of the book is that it covers aspects of both basic research and clinical medicine. Herpesviridae, a family of double-strand DNA viruses, has unique biological features by which these viruses establish latency after primary infection and reactivate in later life. Nine human herpesviruses are known so far, and each of them causes a variety of diseases in both primary infection and reactivation. Since the discovery of each human herpesvirus, an abundance of findings related to them has accumulated in basic research and clinical medicine. However, the vast majority of biological features is still masked in mystery. Furthermore, a strategy of treatment and prevention has not yet been established for most human herpesviruses. A wide range of readers will be interested in this volume with its treatment of problematic points and latest findings in the field.
Author :Kathirvel Subramaniam Publisher :Springer Science & Business Media ISBN 13 :0387859225 Total Pages :454 pages Book Rating :4.3/5 (878 download)
Book Synopsis Anesthesia and Perioperative Care for Aortic Surgery by : Kathirvel Subramaniam
Download or read book Anesthesia and Perioperative Care for Aortic Surgery written by Kathirvel Subramaniam and published by Springer Science & Business Media. This book was released on 2011-01-06 with total page 454 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first of its kind - a comprehensive reference for anesthesia and perioperative clinicians involved in aortic surgery. With a primary focus on anesthesia for various aortic surgical procedures, including endovascular aortic surgery, the title also provides expanded coverage of CNS monitoring and protection, intraoperative transesophageal echocardiography, renal and spinal cord protection during surgery, management of aortic trauma, and postoperative care. Written by top cardiac anesthesiologists, surgeons, and intensivists, this indispensable reference provides everything you need to know about the burgeoning field of aortic surgery in one handy volume.
Book Synopsis Sustainable Communication Networks and Application by : P. Karuppusamy
Download or read book Sustainable Communication Networks and Application written by P. Karuppusamy and published by Springer Nature. This book was released on 2021-01-25 with total page 683 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes novel and state-of-the-art research discussions that articulate and report all research aspects, including theoretical and experimental prototypes and applications that incorporate sustainability into emerging applications. In recent years, sustainability and information and communication technologies (ICT) are highly intertwined, where sustainability resources and its management has attracted various researchers, stakeholders, and industrialists. The energy-efficient communication technologies have revolutionized the various smart applications like smart cities, healthcare, entertainment, and business. The book discusses and articulates emerging challenges in significantly reducing the energy consumption of communication systems and also explains development of a sustainable and energy-efficient mobile and wireless communication network. It includes best selected high-quality conference papers in different fields such as internet of things, cloud computing, data mining, artificial intelligence, machine learning, autonomous systems, deep learning, neural networks, renewable energy sources, sustainable wireless communication networks, QoS, network sustainability, and many other related areas.
