Development Of A Kinetic Model And Calculation Of Radiation Dose Estimates For Sodium Iodide 131i In Athyroid Individuals

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Development of a Kinetic Model and Calculation of Radiation Dose Estimates for Sodium Iodide-131I in Athyroid Individuals

Author :
Publisher :
ISBN 13 :
Total Pages : 94 pages
Book Rating : 4.:/5 (684 download)

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Book Synopsis Development of a Kinetic Model and Calculation of Radiation Dose Estimates for Sodium Iodide-131I in Athyroid Individuals by :

Download or read book Development of a Kinetic Model and Calculation of Radiation Dose Estimates for Sodium Iodide-131I in Athyroid Individuals written by and published by . This book was released on 1997 with total page 94 pages. Available in PDF, EPUB and Kindle. Book excerpt: The treatment for some thyroid carcinomas involves surgically removing the thyroid gland and administering the radiopharmaceutical Sodium iodide-131I (NaI). A diagnostic dose of NaI is given to the patient to determine if remnant tissue from the gland remains or larger doses are administered in order to treat the malignant tissue. Past research regarding NaI uptake and retention in euthyroid individuals (normal functioning thyroid) reveal that radioiodine concentrates mainly in the thyroid tissue and the remaining material is excreted from the body. The majority of radioiodine in athyroid (without thyroid) individuals is also eliminated from the body; however, there has been recent evidence of a long-term retention phase for individuals with no radioiodine concentrating tissue. The general purpose of this study was to develop a kinetic model and estimate the absorbed dose to athyroid individuals regarding the distribution and retention of NaI.

Fundamentals of Nuclear Medicine Dosimetry

Author : Michael G. Stabin
Publisher : Springer Science & Business Media
ISBN 13 : 0387745793
Total Pages : 241 pages
Book Rating : 4.3/5 (877 download)

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Book Synopsis Fundamentals of Nuclear Medicine Dosimetry by : Michael G. Stabin

Download or read book Fundamentals of Nuclear Medicine Dosimetry written by Michael G. Stabin and published by Springer Science & Business Media. This book was released on 2008-01-15 with total page 241 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by a leading international authority in the field, this book is ideal for physicians and residents in nuclear medicine who want to improve their knowledge in internal dosimetry. The text is a practical introduction that guides the reader through fundamental concepts in the calculation of radiation dose, including discussions of standardized models, methods of calculations, and available software applications. This comprehensive guide discusses too the biological effects of radiation on living systems. The book also includes an overview of regulatory aspects related to the radiation dosimetry of new radiopharmaceuticals.

The Practice of Internal Dosimetry in Nuclear Medicine

Author : Michael G. Stabin
Publisher : CRC Press
ISBN 13 : 1482245884
Total Pages : 219 pages
Book Rating : 4.4/5 (822 download)

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Book Synopsis The Practice of Internal Dosimetry in Nuclear Medicine by : Michael G. Stabin

Download or read book The Practice of Internal Dosimetry in Nuclear Medicine written by Michael G. Stabin and published by CRC Press. This book was released on 2016-10-14 with total page 219 pages. Available in PDF, EPUB and Kindle. Book excerpt: Written by one of the world's leading experts in the field of nuclear medicine dosimetry, this text describes in detail the use of internal dose calculations in the practice of nuclear medicine. While radiation therapy with external sources of radiation always employs calculations of dose to optimize therapy for each patient, this is not routinely conducted in nuclear medicine therapy. As the trend towards an increasing role of dosimetry in therapy planning increases, this book reviews the available methods and technologies available to make this a more common practice. The book begins by covering the mathematical fundamentals of internal dose calculations, and uses sample calculations to demonstrate key principles. The book then moves forward to describe anthropomorphic models, dosimetric models, and types and uses of diagnostic and therapeutic radiopharmaceuticals. The depth of coverage makes it useful reference and guide for researchers performing dose calculations and for physicians considering incorporating dose calculations into the treatment of their cancer patients.

Toxicological Profile for Iodine

Author :
Publisher :
ISBN 13 :
Total Pages : 588 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Toxicological Profile for Iodine by :

Download or read book Toxicological Profile for Iodine written by and published by . This book was released on 2004 with total page 588 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Fundamentals of Nuclear Pharmacy

Author : Gopal B. Saha
Publisher : Springer
ISBN 13 : 3319575805
Total Pages : 430 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Fundamentals of Nuclear Pharmacy by : Gopal B. Saha

Download or read book Fundamentals of Nuclear Pharmacy written by Gopal B. Saha and published by Springer. This book was released on 2017-11-11 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases. In keeping up with new developments, the Seventh Edition of Fundamentals of Nuclear Pharmacy chronicles the advancements in radiopharmaceuticals and their use in clinical applications. It discusses basic concepts such as the atom, radioactive decay, instrumentation and production of radionuclides, and explores the design, labeling, characteristics and quality control of radiopharmaceuticals. Radiation regulations and diagnostic and therapeutic applications of radiopharmaceuticals are detailed. Thoroughly updated, the Seventh Edition includes new topics such as alternative productions of 99Mo; production of 64Cu, 86Y, 89Zr, 177Lu, 223Ra; synthesis and clinical uses of new radiopharmaceuticals such as DaTscan, Xofigo, Amyvid, Neuraceq, Vizamyl, Axumin and 68Ga-DOTATATE; dosimetry of new radiopharmaceuticals; theranostic agents and translational medicine. It features numerous examples, diagrams, and images to further clarify the information and offers end- of-chapter questions to help readers assess their comprehension of the material. Recognized as a classic text on nuclear chemistry and pharmacy and acclaimed for its concise and easy-to-understand presentation, Fundamentals of Nuclear Pharmacy is an authoritative resource for nuclear medicine physicians, residents, students, and technologists.

Taking an Exposure History

Author : Arthur L. Frank
Publisher :
ISBN 13 :
Total Pages : 60 pages
Book Rating : 4.:/5 (319 download)

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Book Synopsis Taking an Exposure History by : Arthur L. Frank

Download or read book Taking an Exposure History written by Arthur L. Frank and published by . This book was released on 2001 with total page 60 pages. Available in PDF, EPUB and Kindle. Book excerpt:

An Introduction to the Physics of Nuclear Medicine

Author : Laura Harkness-Brennan
Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643270346
Total Pages : 95 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis An Introduction to the Physics of Nuclear Medicine by : Laura Harkness-Brennan

Download or read book An Introduction to the Physics of Nuclear Medicine written by Laura Harkness-Brennan and published by Morgan & Claypool Publishers. This book was released on 2018-06-27 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: The complexity and vulnerability of the human body has driven the development of a diverse range of diagnostic and therapeutic techniques in modern medicine. The Nuclear Medicine procedures of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and Radionuclide Therapy are well-established in clinical practice and are founded upon the principles of radiation physics. This book will offer an insight into the physics of nuclear medicine by explaining the principles of radioactivity, how radionuclides are produced and administered as radiopharmaceuticals to the body and how radiation can be detected and used to produce images for diagnosis. The treatment of diseases such as thyroid cancer, hyperthyroidism and lymphoma by radionuclide therapy will also be explored.

Nuclear Medicine Resources Manual

Author : International Atomic Energy Agency
Publisher : International Atomic Energy Agency
ISBN 13 : 9789201040190
Total Pages : pages
Book Rating : 4.0/5 (41 download)

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Book Synopsis Nuclear Medicine Resources Manual by : International Atomic Energy Agency

Download or read book Nuclear Medicine Resources Manual written by International Atomic Energy Agency and published by International Atomic Energy Agency. This book was released on 2021-03-22 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: Medical imaging is crucial in a variety of medical settings and at all levels of health care. In public health and preventive medicine as well as in both curative and palliative care, effective decisions depend on correct diagnoses. This edition addresses the most current needs and offers guidance on clinical practice, radiation safety and patient protection, human resource development and training required for the overall practice of nuclear medicine.

Thyroid, Obesity and Metabolism

Author : Livio Luzi
Publisher : Springer Nature
ISBN 13 : 3030802671
Total Pages : 268 pages
Book Rating : 4.0/5 (38 download)

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Book Synopsis Thyroid, Obesity and Metabolism by : Livio Luzi

Download or read book Thyroid, Obesity and Metabolism written by Livio Luzi and published by Springer Nature. This book was released on 2021-08-27 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book will provide readers with up-to-date information on thyroid diseases, obesity and metabolic syndrome. The innovative element is the presentation and exploration of possible connections linking thyroid diseases and metabolism dysfunction. Starting from the classification and diagnosis of thyroid diseases, obesity and metabolic syndrome, techniques to study and treat each of the mentioned diseases are given in an easy-to-use way. This volume will be a useful tool for endocrinologists, diabetologists, dieticians, and any professionals involved in the treatment of thyroid diseases.

Radiopharmaceuticals for Therapy

Author : F. F. (Russ) Knapp
Publisher : Springer
ISBN 13 : 8132226070
Total Pages : 357 pages
Book Rating : 4.1/5 (322 download)

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Book Synopsis Radiopharmaceuticals for Therapy by : F. F. (Russ) Knapp

Download or read book Radiopharmaceuticals for Therapy written by F. F. (Russ) Knapp and published by Springer. This book was released on 2016-01-20 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

Iodine Deficiency in Europe

Author : F. Delange
Publisher : Springer Science & Business Media
ISBN 13 : 1489912452
Total Pages : 467 pages
Book Rating : 4.4/5 (899 download)

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Book Synopsis Iodine Deficiency in Europe by : F. Delange

Download or read book Iodine Deficiency in Europe written by F. Delange and published by Springer Science & Business Media. This book was released on 2013-11-21 with total page 467 pages. Available in PDF, EPUB and Kindle. Book excerpt: The disorders induced by iodine deficiency affect at least one billion people. Because ofits effects on brain development, iodinedeficiency is the single most preventable cause of mental retardation in the world. Therefore, the United Nations and the Heads of State of almost all the world's countries represented at the Summit for Children in 1990 adopted resolutions to eradicate the disorders induced by iodine deficiency (IDD) by the year 2000. For geological and socio-economic reasons, most of the populations affected by iodine deficiency disorders live in isolated and usually mountainous areas, in pre industrialized parts ofthe world. The problem of iodine deficiency in Europe has been greatly underestimated in the last decades. After the remarkable studies on the effects of iodine deficiency and their prevention and correction in Switzerland, IDD was generally considered no longer a significant public health problem in Europe. However, surveys carried out in the early 1980's under the auspices of the European Thyroid Association, clearly demonstrated the persistence of moderately or even severely affected areas. These surveys also highlighted the lack ofinformation about large parts ofEurope, especially its eastern part. It is only quite recently, following major changes in international relations and thanks to the support of UNICEF, WHO, the International Council for the Control of Iodine Deficiency Disorders and the European Thyroid Association, that more extensive surveys have been conducted in several parts of Europe hitherto almost unexplored. These surveys showed that most European countries were iodine deficient.

Protein-Nanoparticle Interactions

Author : Masoud Rahman
Publisher : Springer Science & Business Media
ISBN 13 : 3642375553
Total Pages : 95 pages
Book Rating : 4.6/5 (423 download)

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Book Synopsis Protein-Nanoparticle Interactions by : Masoud Rahman

Download or read book Protein-Nanoparticle Interactions written by Masoud Rahman and published by Springer Science & Business Media. This book was released on 2013-06-24 with total page 95 pages. Available in PDF, EPUB and Kindle. Book excerpt: In recent years, the fabrication of nanomaterials and exploration of their properties have attracted the attention of various scientific disciplines such as biology, physics, chemistry, and engineering. Although nanoparticulate systems are of significant interest in various scientific and technological areas, there is little known about the safety of these nanoscale objects. It has now been established that the surfaces of nanoparticles are immediately covered by biomolecules (e.g. proteins, ions, and enzymes) upon their entrance into a biological medium. This interaction with the biological medium modulates the surface of the nanoparticles, conferring a “biological identity” to their surfaces (referred to as a “corona”), which determines the subsequent cellular/tissue responses. The new interface between the nanoparticles and the biological medium/proteins, called “bio-nano interface,” has been very rarely studied in detail to date, though the interest in this topic is rapidly growing. In this book, the importance of the physiochemical characteristics of nanoparticles for the properties of the protein corona is discussed in detail, followed by comprehensive descriptions of the methods for assessing the protein-nanoparticle interactions. The advantages and limitations of available corona evaluation methods (e.g. spectroscopy methods, mass spectrometry, nuclear magnetic resonance, electron microscopy, X-ray crystallography, and differential centrifugal sedimentation) are examined in detail, followed by a discussion of the possibilities for enhancing the current methods and a call for new techniques. Moreover, the advantages and disadvantages of protein-nanoparticle interaction phenomena are explored and discussed, with a focus on the biological impacts.

Nuclear Medicine: The Requisites

Author : Harvey A. Ziessman, MD
Publisher : Elsevier Health Sciences
ISBN 13 : 0323082998
Total Pages : 466 pages
Book Rating : 4.3/5 (23 download)

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Book Synopsis Nuclear Medicine: The Requisites by : Harvey A. Ziessman, MD

Download or read book Nuclear Medicine: The Requisites written by Harvey A. Ziessman, MD and published by Elsevier Health Sciences. This book was released on 2013-03-21 with total page 466 pages. Available in PDF, EPUB and Kindle. Book excerpt: Get the essential tools you need to make an accurate diagnosis with Nuclear Medicine: The Requisites! The newest edition of his bestselling volume by Drs. Harvey Ziessman, Janis O'Malley, and James Thrall delivers the conceptual, factual, and interpretive information you need for effective clinical practice in nuclear medicine imaging, as well as for certification and recertification review. Prepare for the written board exam and for clinical practice with critical information on nuclear medicine physics, detection and instrumentation, SPECT and PET imaging, and clinical nuclear medicine imaging. Get the best results from today's most technologically advanced approaches, including hybrid imaging, PET/CT, and SPECT/CT, as well as recent developments in instrumentation, radiopharmaceuticals, and molecular imaging. Clearly visualize the findings you're likely to see in practice and on exams with nearly 200 vibrant new full-color images. Access the fully searchable text and downloadable images online at www.expertconsult.com.

An Introduction to Medical Physics

Author : Muhammad Maqbool
Publisher : Springer
ISBN 13 : 3319615408
Total Pages : 422 pages
Book Rating : 4.3/5 (196 download)

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Book Synopsis An Introduction to Medical Physics by : Muhammad Maqbool

Download or read book An Introduction to Medical Physics written by Muhammad Maqbool and published by Springer. This book was released on 2017-11-11 with total page 422 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book begins with the basic terms and definitions and takes a student, step by step, through all areas of medical physics. The book covers radiation therapy, diagnostic radiology, dosimetry, radiation shielding, and nuclear medicine, all at a level suitable for undergraduates. This title not only describes the basics concepts of the field, but also emphasizes numerical and mathematical problems and examples. Students will find An Introduction to Medical Physics to be an indispensible resource in preparations for further graduate studies in the field.

Basic Sciences of Nuclear Medicine

Author : Magdy Khalil
Publisher : Springer Science & Business Media
ISBN 13 : 3540859624
Total Pages : 420 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Basic Sciences of Nuclear Medicine by : Magdy Khalil

Download or read book Basic Sciences of Nuclear Medicine written by Magdy Khalil and published by Springer Science & Business Media. This book was released on 2010-10-26 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nuclear medicine has become an ever-changing and expanding diagnostic and therapeutic medical profession. The day-to-day innovations seen in the field are, in great part, due to the integration of many scientific bases with complex technologic advances. The aim of this reference book, Basic Sciences of Nuclear Medicine, is to provide the reader with a comprehensive and detailed discussion of the scientific bases of nuclear medicine, covering the different topics and concepts that underlie many of the investigations and procedures performed in the field. Topics include radiation and nuclear physics, Tc-99m chemistry, single-photon radiopharmaceuticals and PET chemistry, radiobiology and radiation dosimetry, image processing, image reconstruction, quantitative SPECT imaging, quantitative cardiac SPECT, small animal imaging (including multimodality hybrid imaging, e.g., PET/CT, SPECT/CT, and PET/MRI), compartmental modeling, and tracer kinetics.

Radiological Sciences Dictionary: Keywords, names and definitions

Author : David Dowsett
Publisher : CRC Press
ISBN 13 : 1444113054
Total Pages : 375 pages
Book Rating : 4.4/5 (441 download)

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Book Synopsis Radiological Sciences Dictionary: Keywords, names and definitions by : David Dowsett

Download or read book Radiological Sciences Dictionary: Keywords, names and definitions written by David Dowsett and published by CRC Press. This book was released on 2009-03-27 with total page 375 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Radiological Sciences Dictionary is a rapid reference guide for all hospital staff employed in diagnostic imaging, providing definitions of over 3000 keywords as applied to the technology of diagnostic radiology.Written in a concise and easy to digest form, the dictionary covers a wide variety of subject matter, including:a radiation legislati

Technetium-99m Pharmaceuticals

Author : Ilse Zolle
Publisher : Springer Science & Business Media
ISBN 13 : 3540339906
Total Pages : 354 pages
Book Rating : 4.5/5 (43 download)

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Book Synopsis Technetium-99m Pharmaceuticals by : Ilse Zolle

Download or read book Technetium-99m Pharmaceuticals written by Ilse Zolle and published by Springer Science & Business Media. This book was released on 2007-01-28 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.