Dendrimer-coated Iron Oxide Theranostic Nanoparticles for Cancer Imaging and Therapy

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Publisher :
ISBN 13 :
Total Pages : 65 pages
Book Rating : 4.:/5 (15 download)

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Book Synopsis Dendrimer-coated Iron Oxide Theranostic Nanoparticles for Cancer Imaging and Therapy by : Duy Khanh Luong

Download or read book Dendrimer-coated Iron Oxide Theranostic Nanoparticles for Cancer Imaging and Therapy written by Duy Khanh Luong and published by . This book was released on 2016 with total page 65 pages. Available in PDF, EPUB and Kindle. Book excerpt: The bleak prognosis for patients diagnosed with metastatic cancer along with the low therapeutic efficacy and the recurrence of cancer in conventional chemotherapy are prompting clinical medicine to adopt a new strategy to detect cancer in early stage and to deliver the anticancer drugs specifically to tumor site to enhance therapeutic efficiency and minimize side effects. The aim of this study is to design a theranostic nanocarrier consisting of iron oxide nanoparticles (SPIONs) for magnetic resonance imaging (MRI) and Polyamidoamine dendrimers conjugated with folic acid (FA-PAMAM) for active targeted delivery of a highly potent but extremely lipophilic anticancer compound 3,4-difluorobenzylidene diferuloylmethane (CDF). The resulting targeted nanoparticles SPIONs@FA-PAMAM-CDF showed a significantly enhanced MR contrast as compared to the non-targeted nanoparticles. When tested on SKOV3 (ovarian cancer cells) and HeLa (cervical cancer cells), the targeted nanoformulations showed a higher accumulation in cancer cells with a better anticancer activity, a larger population of apoptotic cells and the ability to upregulate tumor suppressor phosphatase and tensin homolog (PTEN) and inhibit nuclear factor kappa B (NF-ÎðB) which further confirmed the ability of the folate decorated nanoparticles for targeted MRI and anticancer drug delivery.

Theranostic Iron-Oxide Based Nanoplatforms in Oncology

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Publisher : Springer Nature
ISBN 13 : 9819965071
Total Pages : 417 pages
Book Rating : 4.8/5 (199 download)

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Book Synopsis Theranostic Iron-Oxide Based Nanoplatforms in Oncology by : Mohammad-Nabil Savari

Download or read book Theranostic Iron-Oxide Based Nanoplatforms in Oncology written by Mohammad-Nabil Savari and published by Springer Nature. This book was released on 2023-10-24 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the most efficient and latest ways to deal with cancer, focusing on IONPs. The book describes some well-designed surface modifications performed through several functional materials over the surface of IONPs, which results in the development of multifunctional IONPs-based delivery nanoplatforms by enhancing solubility, stability, and avoiding side effects on healthy cells. Several types of stimuli-responsive IONPs-based strategies are also discussed. Owing to magnetic, structural, and thermal properties, IONPs themselves can be utilized for magnetic targeting, magnetic hyperthermia, and phototherapy. Significant advancements are presented in IONPs-based immunotherapy, radiotherapy, and sonodynamic therapy for the efficient treatment of cancer. Finally, the book presents RIONs which serve as the parent platform for the development of powerful DMCAs utilized in SPECT/MRI and PET/MRI applications.

Multifunctional Theranostic Nanomedicines in Cancer

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Publisher : Academic Press
ISBN 13 : 0128217006
Total Pages : 428 pages
Book Rating : 4.1/5 (282 download)

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Book Synopsis Multifunctional Theranostic Nanomedicines in Cancer by : Malay K. Das

Download or read book Multifunctional Theranostic Nanomedicines in Cancer written by Malay K. Das and published by Academic Press. This book was released on 2021-03-16 with total page 428 pages. Available in PDF, EPUB and Kindle. Book excerpt: Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Dendrimers in Nanomedicine

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Publisher : CRC Press
ISBN 13 : 1315340844
Total Pages : 396 pages
Book Rating : 4.3/5 (153 download)

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Book Synopsis Dendrimers in Nanomedicine by : Delphine Felder-Flesch

Download or read book Dendrimers in Nanomedicine written by Delphine Felder-Flesch and published by CRC Press. This book was released on 2016-10-26 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanomedicine can take advantage of the recent developments in nanobiotechnology research for the creation of platforms with superior drug carrier capabilities, selective responsiveness to the environment, unique contrast enhancement profiles, and improved accumulation at the disease site. This book provides a broad glimpse of how various dendritic nanomaterials have been designed and used as efficient tools for nanomedicine. It comprises a pedagogic introduction to dendrimers and hyperbranched systems and their classical and accelerated syntheses through cutting-edge methodologies. The chapters on dendronized magnetic nanoparticles as theranostics, dendrimers in theory (molecular simulations), siRNA delivery with dendrimers, and dendrimers for image-guided therapy, combined with chapters focused on specific types of dendrimers or hyperbranched structures, detail the cutting-edge research in nanomedicine. Finally, a detailed chapter on issues related to the pharmacokinetics and biodistribution of dendrimers helps choose the right structures for successful transfer from bench to bedside. This book will appeal to those involved in nanobiotechnology, macromolecular science, cancer therapy, tissue repair, and siRNA delivery research.

Nanotheranostics for Cancer Applications

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Publisher : Springer
ISBN 13 : 3030017753
Total Pages : 484 pages
Book Rating : 4.0/5 (3 download)

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Book Synopsis Nanotheranostics for Cancer Applications by : Prakash Rai

Download or read book Nanotheranostics for Cancer Applications written by Prakash Rai and published by Springer. This book was released on 2018-11-12 with total page 484 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

Magnetic Nanoparticles in Human Health and Medicine

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Publisher : John Wiley & Sons
ISBN 13 : 1119754747
Total Pages : 512 pages
Book Rating : 4.1/5 (197 download)

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Book Synopsis Magnetic Nanoparticles in Human Health and Medicine by : Costica Caizer

Download or read book Magnetic Nanoparticles in Human Health and Medicine written by Costica Caizer and published by John Wiley & Sons. This book was released on 2021-09-08 with total page 512 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Nanoparticles in Human Health and Medicine Explores the application of magnetic nanoparticles in drug delivery, magnetic resonance imaging, and alternative cancer therapy Magnetic Nanoparticles in Human Health and Medicine addresses recent progress in improving diagnosis by magnetic resonance imaging (MRI) and using non-invasive and non-toxic magnetic nanoparticles for targeted drug delivery and magnetic hyperthermia. Focusing on cancer diagnosis and alternative therapy, the book covers both fundamental principles and advanced theoretical and experimental research on the magnetic properties, biocompatibilization, biofunctionalization, and application of magnetic nanoparticles in nanobiotechnology and nanomedicine. Chapters written by a panel of international specialists in the field of magnetic nanoparticles and their applications in biomedicine cover magnetic hyperthermia (MHT), MRI contrast agents, biomedical imaging, modeling and simulation, nanobiotechnology, toxicity issues, and more. Readers are provided with accurate information on the use of magnetic nanoparticles in diagnosis, drug delivery, and alternative cancer therapeutics—featuring discussion of current problems, proposed solutions, and future research directions. Topics include current applications of magnetic iron oxide nanoparticles in nanomedicine and alternative cancer therapy: drug delivery, magnetic resonance imaging, superparamagnetic hyperthermia as alternative cancer therapy, magnetic hyperthermia in clinical trials, and simulating the physics of magnetic particle heating for cancer therapy. This comprehensive volume: Covers both general research on magnetic nanoparticles in medicine and specific applications in cancer therapeutics Discusses the use of magnetic nanoparticles in alternative cancer therapy by magnetic and superparamagnetic hyperthermia Explores targeted medication delivery using magnetic nanoparticles as a future replacement of conventional techniques Reviews the use of MRI with magnetic nanoparticles to increase the diagnostic accuracy of medical imaging Magnetic Nanoparticles in Human Health and Medicine is a valuable resource for researchers in the fields of nanomagnetism, magnetic nanoparticles, nanobiomaterials, nanobioengineering, biopharmaceuticals nanobiotechnologies, nanomedicine, and biopharmaceuticals, particularly those focused on alternative cancer diagnosis and therapeutics.

Handbook of Polymer and Ceramic Nanotechnology

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Publisher : Springer
ISBN 13 : 9783030405120
Total Pages : 1667 pages
Book Rating : 4.4/5 (51 download)

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Book Synopsis Handbook of Polymer and Ceramic Nanotechnology by : Chaudhery Mustansar Hussain

Download or read book Handbook of Polymer and Ceramic Nanotechnology written by Chaudhery Mustansar Hussain and published by Springer. This book was released on 2021-09-13 with total page 1667 pages. Available in PDF, EPUB and Kindle. Book excerpt: This handbook examines the recent advances in the nanotechnology of polymers and ceramics, which possess outstanding mechanical properties and compatibility given their unique physical and chemical properties caused by the unusually large surface area to volume ratios and high interfacial reactivity. This handbook highlights the various compositions and morphologies of polymer and ceramic nanomaterials that can serve as powerful tools for the diverse applications in areas such as electronics, photonics, shape-memory alloys, biomaterials and biomedical nanomaterials, graphene-based technologies, and textiles and packaging. The handbook addresses safety, economics, green production and sustainability. The book contains a section on functionalization of these molecules, which only increases the possibility of developing even more versatile materials that can be fine-tuned for specific applications. Filling a gap in the literature, this handbook provides comprehensive coverage of properties, fabrication, characterization, functionalization methods and applications at both experimental and theoretical models scales. Economic, toxicological, regulatory, and environmental concerns regarding applications are also discussed in detail. Special attention is paid to sustainable approaches that reduce costs in terms of chemicals and time consumption. The book covers research trends, challenges, and prospective topics as well.

Iron Oxide Nanoparticles for Biomedical Applications

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Publisher : Elsevier
ISBN 13 : 0081012756
Total Pages : 336 pages
Book Rating : 4.0/5 (81 download)

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Book Synopsis Iron Oxide Nanoparticles for Biomedical Applications by : Sophie Laurent

Download or read book Iron Oxide Nanoparticles for Biomedical Applications written by Sophie Laurent and published by Elsevier. This book was released on 2017-10-20 with total page 336 pages. Available in PDF, EPUB and Kindle. Book excerpt: Iron Oxide Nanoparticles for Biomedical Applications: Synthesis, Functionalization and Application begins with several chapters covering the synthesis, stabilization, physico-chemical characterization and functionalization of iron oxide nanoparticles. The second part of the book outlines the various biomedical imaging applications that currently take advantage of the magnetic properties of iron oxide nanoparticles. Brief attention is given to potential iron oxide based therapies, while the final chapter covers nanocytotoxicity, which is a key concern wherever exposure to nanomaterials might occur. This comprehensive book is an essential reference for all those academics and professionals who require thorough knowledge of recent and future developments in the role of iron oxide nanoparticles in biomedicine. Unlocks the potential of iron oxide nanoparticles to transform diagnostic imaging techniques Contains full coverage of new developments and recent research, making this essential reading for researchers and engineers alike Explains the synthesis, processing and characterization of iron oxide nanoparticles with a view to their use in biomedicine

Nanomaterials for Cancer Detection Using Imaging Techniques and Their Clinical Applications

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Publisher : Springer Nature
ISBN 13 : 3031096363
Total Pages : 525 pages
Book Rating : 4.0/5 (31 download)

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Book Synopsis Nanomaterials for Cancer Detection Using Imaging Techniques and Their Clinical Applications by : Ramesh S. Chaughule

Download or read book Nanomaterials for Cancer Detection Using Imaging Techniques and Their Clinical Applications written by Ramesh S. Chaughule and published by Springer Nature. This book was released on 2022-10-17 with total page 525 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book presents nanomaterials for cancer detection using a variety of state-of-the-art imaging techniques. Clinical applications are also highlighted. The unique size-dependent properties and convenient surfaces for molecular assembly make these nanomaterials essential for a variety of innovative imaging techniques. This book covers important imaging modalities, synthesis of nanoparticles with specific functional properties, and clinical applications including the development of anticancer drugs. The information presented here involves contributions from chemistry, materials science, materials characterization, cell engineering, and clinical testing. The book will be essential reading to experienced clinicians as well as a wide range of scholars and researchers interested in nanotechnology and imaging techniques for cancer detection.

Nanomaterials for Tumor Targeting Theranostics

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Publisher : World Scientific
ISBN 13 : 9814635421
Total Pages : 430 pages
Book Rating : 4.8/5 (146 download)

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Book Synopsis Nanomaterials for Tumor Targeting Theranostics by : Mingqian Tan

Download or read book Nanomaterials for Tumor Targeting Theranostics written by Mingqian Tan and published by World Scientific. This book was released on 2016 with total page 430 pages. Available in PDF, EPUB and Kindle. Book excerpt: "Nanomaterials offer great potential for effective tumor diagnosis and therapy combing diagnostic agents and therapeutic drugs into one platform. In this book, the most recent progress of main nanomaterials and their applications in tumor targeting theranostics is presented. It summarizes the recent advances of current principal nanomaterials in tumor theranostics, including magnetic nanomaterials, quantum dots, mesoporous silica nanoparticles, gold nanomaterials, polymeric nanosystem, carbon nanomaterials, lipopolyplex nanoparticles, microbubbles, upconversion nanomaterials and dendrimers. It will enable readers to get a more realistic understanding of both the advantages and limitations of nanomaterials for potential tumor targeting theranosis. The publication of this book will accelerate the spread of ideas that are currently trickling through the scientific literature. Also a greater understanding of the potential and challenge of nanomaterials for tumor targeting theranostics is highly anticipated for practical clinical use."--Provided by publisher.

Handbook of Nanomaterials for Cancer Theranostics

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Publisher : Elsevier
ISBN 13 : 0128133406
Total Pages : 608 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Handbook of Nanomaterials for Cancer Theranostics by : Joao Conde

Download or read book Handbook of Nanomaterials for Cancer Theranostics written by Joao Conde and published by Elsevier. This book was released on 2018-06-27 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics

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Publisher : Morgan & Claypool Publishers
ISBN 13 : 1643277863
Total Pages : 50 pages
Book Rating : 4.6/5 (432 download)

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Book Synopsis Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics by : Sudip Mukherjee

Download or read book Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics written by Sudip Mukherjee and published by Morgan & Claypool Publishers. This book was released on 2019-10-29 with total page 50 pages. Available in PDF, EPUB and Kindle. Book excerpt: In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.

Hybrid Nanostructures for Cancer Theranostics

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Publisher : Elsevier
ISBN 13 : 0128139072
Total Pages : 276 pages
Book Rating : 4.1/5 (281 download)

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Book Synopsis Hybrid Nanostructures for Cancer Theranostics by : Raghvendra Ashok Bohara

Download or read book Hybrid Nanostructures for Cancer Theranostics written by Raghvendra Ashok Bohara and published by Elsevier. This book was released on 2018-11-19 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Hybrid nanostructures are nanoparticles which incorporate two or more structures. These structures may represent organic or inorganic material, but they synergistically improve the application of the material for end users. Hybrid Nanostructures for Cancer Theranostics explores how hybrid nanostructures are used in cancer treatment. Focusing on the properties of hybrid nanostructures, the book demonstrates how their unique characteristics can be used to create more effective treatment techniques. In the second half of the book, the chapters examine how hybrid nanostructures are currently being used in practice, assessing the pros and cons of using different types of nanostructures for different treatments. This valuable resource will allow readers to understand the core and emerging concept of functionalization, bioconjugation, hyperthermia and phototherapy of nanoparticles which allows for the greater use of hybrid nanomaterials in cancer theranostics. Shows how the use of novel hybrid nanostructures can lead to more effective cancer treatments. Explores how hybrid nanostructures are used for different treatment types, including photo thermal therapy and drug delivery. Explains how the use of hybrid nanostructures can lead to more rapid cancer diagnosis.

Cetuximab-conjugated Iron Oxide Nanoparticles for Cancer Imaging and Therapy

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Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (928 download)

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Book Synopsis Cetuximab-conjugated Iron Oxide Nanoparticles for Cancer Imaging and Therapy by :

Download or read book Cetuximab-conjugated Iron Oxide Nanoparticles for Cancer Imaging and Therapy written by and published by . This book was released on 2015 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:

Magnetic Nanoparticles for Targeted Cancer Theranostics

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Publisher :
ISBN 13 :
Total Pages : 135 pages
Book Rating : 4.:/5 (949 download)

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Book Synopsis Magnetic Nanoparticles for Targeted Cancer Theranostics by : Zachary R. Stephen

Download or read book Magnetic Nanoparticles for Targeted Cancer Theranostics written by Zachary R. Stephen and published by . This book was released on 2016 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt: Nanotechnology has given scientists new tools for the development of advanced materials for the detection, diagnosis and treatment of disease. Superparamagnetic iron oxide nanoparticles (SPIONs) in particular have been extensively investigated as novel magnetic resonance imaging (MRI) contrast agents due to a combination of favorable superparamagnetic properties, biodegradability, and surface properties that allow modification for improved in vivo kinetics and multifunctionality. SPIONs favorable characteristics have further led to their investigation as promising theranostic agents, which combine imaging and therapeutic capabilities in a single nanovector. The combination of imaging and therapy could allow for real-time monitoring of drug delivery and the tailoring of treatment for individual patients with the promise of improved clinical outcomes for patients suffering from cancers such as glioblastoma (GBM). This dissertation is intended to address limitation of conventional clinical cancer treatment including current cancer targeting limitations and poor pharmacokinetic of hydrophobic chemotherapeutics that lead to unacceptable side effects. First, SPIONs were coated with cross-linked, redox-responsive copolymers composed of chitosan and polyethylene glycol (PEG), functionalized with cancer targeting agent chlorotoxin (CTX), and modified with O6-benzylguanine (BG), an O6-methylguanine-DNA methyltransferase (MGMT) inhibitor to improve temozolomide based treatments of GBMs. It was found that CED of the BG loaded SPION were more tolerable than free drug and increased survival 3-fold over untreated animals in an intracranial GBM mouse model. Next, analogs of BG were evaluated for their inhibitory efficacy and modified to allow for polymerization on the SPION surface via hydrazone linkages to facilitate improved drug loading and controlled drug release. Finally, a new synthesis and functionalization strategy for theranostic agents is presented that demonstrated streamlined production, allowed for great control over the display of functional moieties on the SPION surface, increased batch to batch consistency, and provided improved magnetic properties.

Magnetic Nanoheterostructures

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Publisher : Springer Nature
ISBN 13 : 3030399230
Total Pages : 495 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Magnetic Nanoheterostructures by : Surender Kumar Sharma

Download or read book Magnetic Nanoheterostructures written by Surender Kumar Sharma and published by Springer Nature. This book was released on 2020-03-02 with total page 495 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book contains most updated information on synthesis of magnetic nanohybrids, their physio-chemical properties, and key biological applications. It highlights the complexity of nanoheterostructures, especially magnetic metal oxides, ferrites and doped magnetic nanomaterials, and discusses their potential applications in the early detection, imaging and treatment of cancer. It also covers the toxicity and risk assessment of multifunctional nanomaterials. Providing an overview of magnetic nanoheterostructures, it appeals to a wide audience, from beginners and graduate-level students to experts in academia and industry.

Dendrimers for Drug Delivery

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Publisher : CRC Press
ISBN 13 : 135136068X
Total Pages : 406 pages
Book Rating : 4.3/5 (513 download)

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Book Synopsis Dendrimers for Drug Delivery by : Anil K. Sharma

Download or read book Dendrimers for Drug Delivery written by Anil K. Sharma and published by CRC Press. This book was released on 2018-07-27 with total page 406 pages. Available in PDF, EPUB and Kindle. Book excerpt: With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features of dendrimers. It goes on to present the details of usual properties, structure, classification, and methods of synthesis, with relevant examples. The toxicity of dendrimers is also discussed. The chapter authors provide an exhaustive amount of information about dendrimers and their biomedical applications, including biocompatibility and toxicity aspects, a very useful feature. This informative volume will be valuable resource that will help readers to create products derived from dendrimers and navigate through the regulatory, manufacturing, and quality control hurdles. It will be an important resource for researchers, scientists, upper-level students, and industry professionals.