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Cyclic Nucleotides In The Central Nervous System
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Book Synopsis Cyclic Nucleotides in the Nervous System by : John Daly
Download or read book Cyclic Nucleotides in the Nervous System written by John Daly and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 408 pages. Available in PDF, EPUB and Kindle. Book excerpt: The elucidation of the cellular and molecular bases underlying the inte grated function of the central nervous system, both in disease and in health, must ultimately come from the combined efforts of scientists from many disciplines, including biology, chemistry, histology, pathology, physiology, pharmacology, and psychology. Communication between scientists from these various disciplines-vital to the advancement of our understanding of the function of the nervous system-has become more and more difficult in recent years. Both increasing specialization and the incredible increases in publications pertinent to brain research in a wide spectrum of journals, in symposium volumes, in monographs, in abstracts, and in reviews contrib ute to the problems of cross-communication and even of communication within a scientific discipline. Research on the significance of cyclic nucleo tides to the function of nervous systems is particularly illustrative of the communication problem. Since the initial publications by Sutherland, Rall, and Butcher in the late fifties and early sixties on high levels of adenylate cyclase, phosphodiesterases, and cyclic AMP in brain, the ensuing litera ture of this field has expanded exponentially. At the present time, from five to ten publications relevant to cyclic nucleotides and the nervous system appear each week. Indeed, these are minimal numbers based mainly on examination of literature titles and key index words. Many articles concerned with some aspect of central function contain, buried within their text, experiments with or related to cyclic nucleotides.
Book Synopsis Cyclic Nucleotides in the Central Nervous System by : Tamas Bartfai
Download or read book Cyclic Nucleotides in the Central Nervous System written by Tamas Bartfai and published by . This book was released on 1978 with total page 3 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System by : Nicholas J. Brandon
Download or read book Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System written by Nicholas J. Brandon and published by John Wiley & Sons. This book was released on 2014-03-07 with total page 429 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
Book Synopsis Cyclic Nucleotides in the Nervous System by : George I. Drummond
Download or read book Cyclic Nucleotides in the Nervous System written by George I. Drummond and published by New York : Raven Press. This book was released on 1984 with total page 142 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cyclic Nucleotides, Cyclic Nucleotide Phosphodiesterase, Protein Kinase, and Phosphoprotein Phosphatase in the Central Nervous System of Manduca Sexta by : Edward Elmo Albin
Download or read book Cyclic Nucleotides, Cyclic Nucleotide Phosphodiesterase, Protein Kinase, and Phosphoprotein Phosphatase in the Central Nervous System of Manduca Sexta written by Edward Elmo Albin and published by . This book was released on 1978 with total page 596 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis The Role of Cyclic Nucleotides in Central Synaptic Function / Renal Transport of Amino Acids by : Floyd E. Bloom
Download or read book The Role of Cyclic Nucleotides in Central Synaptic Function / Renal Transport of Amino Acids written by Floyd E. Bloom and published by Springer-Verlag. This book was released on 2019-06-12 with total page 204 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cyclic Nucleotide Signaling by : Xiaodong Cheng
Download or read book Cyclic Nucleotide Signaling written by Xiaodong Cheng and published by CRC Press. This book was released on 2015-05-07 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: Showcasing the recent progresses of the field, Cyclic Nucleotide Signaling covers the major tools and methodologies used in various areas of research. The majority of the chapters are protocol oriented, with the goal of providing clear directions for laboratory use. Students and investigators new to the field will find this book particularly inform
Book Synopsis Neurotransmitters, Cyclic Nucleotides, and Adenyl Cyclase in the Central Nervous System of Manduca Sexta by : Duncan Paul Taylor
Download or read book Neurotransmitters, Cyclic Nucleotides, and Adenyl Cyclase in the Central Nervous System of Manduca Sexta written by Duncan Paul Taylor and published by . This book was released on 1977 with total page 278 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Effects of Psychoactive Drugs on Cyclic Nucleotides in the Central Nervous System by : Gene C. Palmer
Download or read book Effects of Psychoactive Drugs on Cyclic Nucleotides in the Central Nervous System written by Gene C. Palmer and published by . This book was released on 1983 with total page 133 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Cyclic Nucleotides in the Nervous System by : George I. Drummond
Download or read book Cyclic Nucleotides in the Nervous System written by George I. Drummond and published by . This book was released on 1984-01-01 with total page 135 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis An Evaluation of Immunohistochemistry for Studying Cyclic Nucleotides in the Central Nervous System, with Particular Reference to Guanosine 3',5'-monophosphate by : R. D. F. Cumming
Download or read book An Evaluation of Immunohistochemistry for Studying Cyclic Nucleotides in the Central Nervous System, with Particular Reference to Guanosine 3',5'-monophosphate written by R. D. F. Cumming and published by . This book was released on 1979 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Neuropharmacology of Cyclic Nucleotides by : Gene C. Palmer
Download or read book Neuropharmacology of Cyclic Nucleotides written by Gene C. Palmer and published by Urban & Schwarzenberg. This book was released on 1979 with total page 328 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Prothoracicotropic Hormone, Cyclic Nucleotides, and Proctolin in Insect Central Nervous System by : Timothy Gilmore Kingan
Download or read book Prothoracicotropic Hormone, Cyclic Nucleotides, and Proctolin in Insect Central Nervous System written by Timothy Gilmore Kingan and published by . This book was released on 1980 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: Prothoracicotropic hormone has been partially purified from whole heads of tobacco hornworm larvae, Manduca sexta. Activity was followed with a larval bioassay. Activity was purified 4400 fold from crude extracts. The hormone was found to be a heat-stable polypeptide with an approximate molecular weight of 25,000 Daltons. The hormone has an isoelectric point in the range pH 5.25-5.50. The most purified preparations were shown to possess activity in vitro with a prothoracic gland culture system. Cyclic AMP and cyclic GMP were quantitated in the central nervous system of Manduca sexta during the pre-metamorphic endocrine activity that leads to a change from feeding to wandering behavior and to the commitment to pupal development. Cyclic AMP and cyclic GMP accumulated in the brain in tandem during this period. Cyclic nucleotide levels remained unchanged in abdominal and thoracic ganglia and in the subesophageal ganglion. Proctolin was quantitated by radioimmunoassay in the central nervous system of the Maderae cockroach, Leucophaea maderae. Proctolin RIA activity was found throughout the CNS, with the sixth abdominal and thoracic ganglia being the richest sources. RIA activity was also found in the cockroach hindgut.
Book Synopsis Central Nervous System by : E. Genazzani
Download or read book Central Nervous System written by E. Genazzani and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 410 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is based on the Symposium "Metabolic Regulation and Functional Activity in the Central Nervous System" which was held on September 16 and 17, 1972, at Saint Vincent (Aosta)/Italy, and was sponsored by the Accademia di Medicina di Torino with the scientific cooperation of the Istituto di Farmacologia, Universita di Torino, and the Pharmakologisches Institut der Freien Universitat Berlin. Its purpose was to give a greater number of scientists from different countries an opportunity to report their latest results under a heading concerning general relationships between metabolism and function. We quite deliberately refrained from pursuing the partly heterogenous subjects into details. Thus, the organizers hoped to be able to interest a greater circle of readers for the manifold subjects from various fields dealing with the investigation of metabolic processes in the central nervous system. The discussion remarks to the lectures could not be considered for printing. The Accademia di Medicina di Torino and all others concerned do not only thank Dr. R. Di Carlo and other members of the Istituto di Farmacologia, Universita di Torino, for the excellent work they performed in preparing this Symposium, but also the Amministrazione Regionale della Valle di Aosta and SIT A V di Saint-Vincent for their generous support and their kind hospitality which made the stay at Saint-Vincent most agreeable for all participants.
Book Synopsis Phosphodiesterases: CNS Functions and Diseases by : Han-Ting Zhang
Download or read book Phosphodiesterases: CNS Functions and Diseases written by Han-Ting Zhang and published by Springer. This book was released on 2017-09-26 with total page 475 pages. Available in PDF, EPUB and Kindle. Book excerpt: PDEs are a family of enzymes that catalyze the hydrolysis of intracellular cyclic nucleotides. They are implicated in a number of disorders and dysfunctions and PDE inhibitors have already proven to be effective therapies for erectile dysfunction, COPD, and psoriatic arthritis. This family of enzymes also plays a role in diseases and disorders of the CNS such as depression, anxiety, schizophrenia, and Alzheimer's Disease. Unfortunately no effective PDE inhibitors have been developed for the treatment of these diseases. The proposed book will be a comprehensive overview of the current state of basic and translational research on PDE inhibitors written by internationally recognized experts. Authors will also discuss potential PDE subtypes and splice variants in the hopes that this will spur more creative approaches to PDE targeting drugs.
Book Synopsis Biochemical Correlates of Brain Structure and Function by : A.N. Davison
Download or read book Biochemical Correlates of Brain Structure and Function written by A.N. Davison and published by Elsevier. This book was released on 2012-12-02 with total page 360 pages. Available in PDF, EPUB and Kindle. Book excerpt: Biochemical Correlates of Brain Structure and Function deals with the biochemical correlates of brain structure and function, providing some examples of contemporary work interrelating structure with function of the nervous system. The developing brain provides a system for this kind of study, but broad correlates are also drawn between changing biochemistry and increasing physiological activity. This book is organized into nine chapters and begins with an overview of biochemical, morphological, and functional changes in the developing brain, as well as the underlying molecular basis of nerve differentiation and growth of the developing brain. An account of the concept of the cell cycle and its control is also given. The reader is methodically introduced to the properties of the developing retina and its functional biochemistry, with specific reference to the cyclic nucleotides; the use of selective lesioning to delineate GABA-ergic and cholinergic tracts as well as the catecholamine pathways; and cerebral blood flow alteration in concert with mental activity. The remaining chapters explore regions of the brain with altered glucose utilization in response to changes in local functional activity; the physiologically important factors regulating the supply of oxygen and glucose and the relation of metabolic rate to the metabolic state of the brain; and varying aspects of behavioral neurochemistry. This book is intended for chemists and biologists as well as students of biochemistry.
