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Author : Christine Marie Ewing
Publisher :
ISBN 13 :
Total Pages : 314 pages
Book Rating : 4.:/5 (221 download)
Download or read book Cross-reactivity Between Klebsiella and HLA B27 in Ankylosing Spondylitis written by Christine Marie Ewing and published by . This book was released on 1991 with total page 314 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Alan Ebringer
Publisher : Springer Science & Business Media
ISBN 13 : 1447143000
Total Pages : 265 pages
Book Rating : 4.4/5 (471 download)
Download or read book Ankylosing spondylitis and Klebsiella written by Alan Ebringer and published by Springer Science & Business Media. This book was released on 2012-11-08 with total page 265 pages. Available in PDF, EPUB and Kindle. Book excerpt: Ankylosing spondylitis and Klebsiella is a comprehensive and informative text on the cause of Ankylosing spondylitis. Ankylosing spondylitis (AS) is a condition which affects 20 million people worldwide and is likely caused or initiated by a bowel infection from Klebsiella bacteria. When a patient is infected by Klebsiella bacteria, his or her immune system will make antibodies against all the antigens or molecules found in the microbe. Because some of the bacterial antigens resemble self tissues, the anti-bacterial antibodies will attack not only the bacteria but also the self tissues such as the joints and the cells having the same HLA molecules, which is how the disease AS starts. This is the concept of molecular similarity or “molecular mimicry” which previously has been found to work in two other autoimmune diseases; rheumatic fever and rheumatoid arthritis. The first paper on this subject was published in 1976 and since then over 100 papers on rheumatological topics have been published, from Prof Ebringer’s group, at the Division of Life Sciences, King’s College in London, UK. The relevant information from these papers is extracted and presented in this book format making it accessible to health professionals, research institutions, pharmaceutical companies and universities and the general public.
Author : Michael B.A. Oldstone
Publisher : Springer Science & Business Media
ISBN 13 : 3642745946
Total Pages : 141 pages
Book Rating : 4.6/5 (427 download)
Download or read book Molecular Mimicry written by Michael B.A. Oldstone and published by Springer Science & Business Media. This book was released on 2013-03-12 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume focuses on the evidence for or against molecular mimicry as a cause of autoimmunity. Contributions from recognized experts present their original findings, and the final chapter reviews the overall perspective of molecular mimicry, how to use its principles in clinical investigation and list the conceptual traits by which autoimmune disaese can occur.
Author : P. Cowling
Publisher :
ISBN 13 :
Total Pages : pages
Book Rating : 4.:/5 (536 download)
Download or read book Gram Negative Bacteria and Ankylosing Spondylitis written by P. Cowling and published by . This book was released on 1981 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author :
Publisher :
ISBN 13 :
Total Pages : 546 pages
Book Rating : 4.:/5 (94 download)
Download or read book Crossreactivity Between HLA B27 Lymphocytes and Gram Negative Bacteria written by and published by . This book was released on 1981 with total page 546 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Luis R. Espinoza
Publisher :
ISBN 13 :
Total Pages : 144 pages
Book Rating : 4.:/5 ( download)
Download or read book Molecular Pathogenic Mechanisms of Spondyloarthropathies written by Luis R. Espinoza and published by . This book was released on 1995 with total page 144 pages. Available in PDF, EPUB and Kindle. Book excerpt: Summarizes recent events in the understanding of molecular pathogenic mechanisms in spondyloarthropathies, such as better characterization of clinical syndromes, the association with HLA-B27 mediated genetic factors, and the role of microorganisms, and covers the clinical and therapeutic aspects of this group of diseases as well. Topics include HLA antigens and seronegative spondyloarthropathies, experimental animal models of the diseases, humoral and cellular immune studies, the role of cytokines, and other genetic factors. Includes bandw photos. Annotation copyright by Book News, Inc., Portland, OR
Author : Dolly Belle Tyan
Publisher :
ISBN 13 :
Total Pages : 376 pages
Book Rating : 4.:/5 ( download)
Download or read book Probing the Enigmatic Association Between Ankylosing Spondylitis and HLA-B27 written by Dolly Belle Tyan and published by . This book was released on 1995 with total page 376 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : J.L. Tiwari
Publisher : Springer Science & Business Media
ISBN 13 : 1461385458
Total Pages : 492 pages
Book Rating : 4.4/5 (613 download)
Download or read book HLA and Disease Associations written by J.L. Tiwari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 492 pages. Available in PDF, EPUB and Kindle. Book excerpt: The human leukocyte antigen (HLA) or tissue types are the products of a rapidly developing field of knowledge within the last 20 years. In the early stages of the research many investigators suspected the existence of a complex series of transplantation antigens, but it was widely believed that these antigens would not be well-defined even in this century. Yet in the last two decades as many as 124 different HLA antigens determined by at least 7 very closely linked genes located on the short arm of chromosome 6 have been identified and subsequently agreed upon by an international nomenclature committee. 1 Extensive international collaboration fueled by the potential clinical application of these antigens to clinical transplantation has advanced the field rapidly. There were nine inter national histocompatibility workshops held during this period. Although iden tification of HLA antigens was of primary clinical importance in transplantation 2 and of great basic interest in human genetics and anthropology, a rather un expected bonus has been the determination that HLA antigens are associated with disease susceptibility to a greater extent than any other known genetic marker in man. In the past, many genetic polymorphisms have been suspected to be associated with diseases. The most extensively studied markers are blood groups, enzymes, and serum proteins. A comprehensive account of published studies, totalling approximately 1,000, of these markers is available in a book by Mourant et al.
Author : Guenter Regling
Publisher : Walter de Gruyter
ISBN 13 : 3110875675
Total Pages : 357 pages
Book Rating : 4.1/5 (18 download)
Download or read book Wolff's Law and Connective Tissue Regulation written by Guenter Regling and published by Walter de Gruyter. This book was released on 2011-03-02 with total page 357 pages. Available in PDF, EPUB and Kindle. Book excerpt: Wolff's Law and Connective Tissue Regulation: Modern Interdisciplinary Comments on Wolff's Law of Connective Tissue Regulation and Rational Understa.
Author : W. J. Dinning
Publisher : Butterworth-Heinemann
ISBN 13 : 1483193519
Total Pages : 260 pages
Book Rating : 4.4/5 (831 download)
Download or read book Systemic Inflammatory Disease and the Eye written by W. J. Dinning and published by Butterworth-Heinemann. This book was released on 2016-08-19 with total page 260 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systemic Inflammatory Disease and the Eye present an overview of the systemic conditions associated with ocular inflammation. It discusses the factors for ocular connection in some conditions. It addresses the nature of ocular lesions and eye infections. Some of the topics covered in the book are the symptoms of inflammation of the eye; the aetiology of sarcoidosis; posterior segment inflammation; pathology and immunology of systemic vasculitis syndromes; aetiology of polyarteritis nodosa; diagnosis of systemic lupus erythematosus; and the different types of Sjogren’s syndrome. The pathology and immunopathology of Keratoconjunctivitis Sicca are fully covered. The diagnosis of rheumatoid arthritis is discussed in detail. The text describes in depth the rheumatoid factors and histopathology of joint lesions. The diagnosis of juvenile chronic polyarthritis is presented completely. A chapter is devoted to the epidemiology and clinical features of ankylosing spondylitis. The book can provide useful information to ophthalmologists, doctors, chemists, students, and researchers.
Author : Robert Inman
Publisher : Oxford University Press
ISBN 13 : 0192520598
Total Pages : 828 pages
Book Rating : 4.1/5 (925 download)
Download or read book Oxford Textbook of Axial Spondyloarthritis written by Robert Inman and published by Oxford University Press. This book was released on 2017-06-30 with total page 828 pages. Available in PDF, EPUB and Kindle. Book excerpt: Axial Spondyloarthritis is a timely addition to the Oxford Textbooks in Rheumatology series, providing a comprehensive reference to this rapidly evolving field. The conceptual framework of the disease has now evolved beyond ankylosing spondylitis to encompass a broader concept of axial inflammation. Earlier recognition has opened the door to earlier intervention, and the understanding of the biologic basis of axial SpA has seen significant advances in recent years. The first textbook to cover axial spondyloarthritis in this level of detail from a global perspective, this volume offers a practical and complete resource compiled by a multidisciplinary and multinational team of experts. Beginning with a historical perspective on the disease, the textbook provides a comprehensive background in the epidemiology, diagnosis, and classification of axial spondyloarthritis. Immune mechanisms and genetics are covered, along with imaging and a detailed section on the range of treatments options currently available. A section on extra-articular manifestations provides a comprehensive knowledge base for the clinician treating patients with spondyloarthritis, and chapters on the economics of the disease, physical functioning, and patient registries complete the broad coverage of the topic. Practical, easy to use, yet detailed with respect to pathophysiology, diagnostics, and management, this textbook provides a comprehensive reference for rheumatologists, general practitioners, internists, and paediatricians managing patients with axial spondyloarthritis.
Author : Moncef Zouali
Publisher : IOS Press
ISBN 13 : 9781586033613
Total Pages : 378 pages
Book Rating : 4.0/5 (336 download)
Download or read book Frontiers in Autoimmunity written by Moncef Zouali and published by IOS Press. This book was released on 2003 with total page 378 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Author : Luis R. Espinoza
Publisher : Springer Nature
ISBN 13 : 3030233111
Total Pages : 460 pages
Book Rating : 4.0/5 (32 download)
Download or read book Infections and the Rheumatic Diseases written by Luis R. Espinoza and published by Springer Nature. This book was released on 2019-09-26 with total page 460 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides a comprehensive and up-to-date review of the basic and clinical aspects of infections and infectious processes that trigger or aggravate a variety of autoimmune and inflammatory musculoskeletal disorders. It delivers a timely update on the interactions between infection and rheumatic diseases in order to provide clinicians with the tools they need for proper diagnosis and treatment. The book is divided into five main sections. The first examines the basic aspects of bacterial infections with a discussion of molecular biology, the microbiome, various types of bacteria that cause infection, and recent advances in biologic therapy. The next section focuses on different forms of viral arthritis including hepatitis arthritis, arthritis associated with alpha viruses, and parvovirus-related arthritis. Subsequent chapters then discuss arthritis caused by mycobacteria, fungi, spirochete, and other miscellaneous arthritides. Following this are various analyzations on reactive arthritis and infection-related rheumatic diseases such as Whipple’s Disease, SAPHO Syndrome, rheumatic fever, and HIV-associated rheumatic manifestations. Finally, the book closes with three chapters on external impacts on infectious diseases such as climate change, vaccinations and systemic lupus erythematosus. Infections and the Rheumatic Diseases is an essential resource for physicians and related professionals, residents, fellows, graduate students, and nurses in rheumatology, clinical immunology, and internal medicine.
Author : Argyrios N Theofilopoulos
Publisher : CRC Press
ISBN 13 : 1482283727
Total Pages : 1973 pages
Book Rating : 4.4/5 (822 download)
Download or read book The Molecular Pathology of Autoimmune Diseases written by Argyrios N Theofilopoulos and published by CRC Press. This book was released on 2002-12-06 with total page 1973 pages. Available in PDF, EPUB and Kindle. Book excerpt: Remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. The Molecular Pathology of Autoimmune Diseases is a concise and centralized resource for information on the topic, with a special focus on the molecula
Author : Gabriel S Panayi
Publisher : Butterworth-Heinemann
ISBN 13 : 1483164616
Total Pages : 417 pages
Book Rating : 4.4/5 (831 download)
Download or read book Immunogenetics written by Gabriel S Panayi and published by Butterworth-Heinemann. This book was released on 2014-05-19 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: Immunogenetics is a 12-chapter book that begins with the elucidation of the major histocompatibility complex genes and their role in autoimmune and infectious diseases. Subsequent chapters explore the human major histocompatibility complex, including implications of their complement genes for linkage disequilibrium and disease associations. This book also describes the genetics of human immunoglobulins; T-cell clones; genes of the major histocompatibility complex of the mouse; and the generation, characterization, and use of monoclonal antibodies of murine and human origin. Specific diseases are also discussed; these include spondoarthritides, rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and autoimmune thyroid disease. This book will be of beneficial value to specialists in infectious diseases, endocrinology, connective tissue diseases, and neurology, as well as to medical scientists in immunology and molecular biology.
Author : Francis V. Chisari
Publisher : Springer Science & Business Media
ISBN 13 : 3642852084
Total Pages : 351 pages
Book Rating : 4.6/5 (428 download)
Download or read book Transgenic Models of Human Viral and Immunological Disease written by Francis V. Chisari and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 351 pages. Available in PDF, EPUB and Kindle. Book excerpt: Most diseases are multifactoral. Transgenic technology permits gene(s) of interest to be expressed in a small manipulatable laboratory animal model. By this process, murine models of human infections can be developed and studied; effects of cytokines in vivo, focally expressed in unique cells can be established and manipulated, and a variety of autoimmune disorders, mimicking human disease can be constructed. In this volume, these approaches for study of human immunodeficiency virus, hepatitis virus, viruses causing tumors and chronic degenerative disorders are described. Also included are chapters of transgenic models of autoimmune disorders like diabetes, systemic lupus and ankylosing spondylitis.
Author : Irun R. Cohen
Publisher : CRC Press
ISBN 13 : 1000083543
Total Pages : 315 pages
Book Rating : 4.0/5 ( download)
Download or read book Perspectives on Autoimmunity written by Irun R. Cohen and published by CRC Press. This book was released on 2020-04-15 with total page 315 pages. Available in PDF, EPUB and Kindle. Book excerpt: First Published in 1988, this book offers a full, comprehensive guide to autoimmunity. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for students of medicine, and other practitioners in their respective fields.
