CRC Handbook of Optical Resolutions via Diastereomeric Salt Formation

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Publisher : CRC Press
ISBN 13 : 1420042602
Total Pages : 708 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis CRC Handbook of Optical Resolutions via Diastereomeric Salt Formation by : David Kozma

Download or read book CRC Handbook of Optical Resolutions via Diastereomeric Salt Formation written by David Kozma and published by CRC Press. This book was released on 2001-10-18 with total page 708 pages. Available in PDF, EPUB and Kindle. Book excerpt: Optically active compounds are gaining ever-increasing importance in organic chemistry, both in the academic and the industrial arenas. The rational synthesis of the growing number of chiral chemicals, drugs, and natural products demands efficient methods for producing these compounds in an enantiomerically, highly pure form. Despite the available

Enantiomer Separation

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Publisher : Springer Science & Business Media
ISBN 13 : 1402023375
Total Pages : 334 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Enantiomer Separation by : Fumio Toda

Download or read book Enantiomer Separation written by Fumio Toda and published by Springer Science & Business Media. This book was released on 2007-11-04 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: In spite of important advances in asymmetric synthesis, chiral compounds cannot all be obtained in a pure state by asymmetric synthesis. As a result, enantiomer separation remains an important technique for obtaining optically active materials. Although asymmetric synthesis is a once-only procedure, an enantiomer separation process can be repeated until the optically pure sample is obtained. This book discusses several new enantiomer separation methods using modern techniques developed by experts in the field. These methods consist mainly of the following three types: 1) Enantiomer separation by inclusion complexation with a chiral host compound 2) Enantiomer separation using biological methods 3) Enantiomer separation by HPLC chromatography using a column containing a chiral stationary phase. Separation of a racemic compound has been called “optical resolution” or simply “resolution”. Nowadays, the descriptions “enantiomer resolution” or “enantiomer separation” are also commonly used. Accordingly, “Enantiomer Separation” is used in the title of this book. The editor and all chapter contributors hope that this book is helpful for scientists and engineers working in this field.

Engineering Crystallography: From Molecule to Crystal to Functional Form

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Publisher : Springer
ISBN 13 : 9402411178
Total Pages : 481 pages
Book Rating : 4.4/5 (24 download)

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Book Synopsis Engineering Crystallography: From Molecule to Crystal to Functional Form by : Kevin J. Roberts

Download or read book Engineering Crystallography: From Molecule to Crystal to Functional Form written by Kevin J. Roberts and published by Springer. This book was released on 2017-07-18 with total page 481 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book highlights the current state-of-the-art regarding the application of applied crystallographic methodologies for understanding, predicting and controlling the transformation from the molecular to crystalline state with the latter exhibiting pre-defined properties. This philosophy is built around the fundamental principles underpinning the three inter-connected themes of Form (what), Formation (how) and Function (why). Topics covered include: molecular and crystal structure, chirality and ferromagnetism, supramolecular assembly, defects and reactivity, morphology and surface energetics. Approaches for preparing crystals and nano-crystals with novel physical, chemical and mechanical properties include: crystallisation, seeding, phase diagrams, polymorphic control, chiral separation, ultrasonic techniques and mechano-chemistry. The vision is realised through examination of a range of advanced analytical characterisation techniques including in-situ studies. The work is underpinned through an unprecedented structural perspective of molecular features, solid-state packing arrangements and surface energetics as well as in-situ studies. This work will be of interest to researchers, industrialists, intellectual property specialists and policy makers interested in the latest developments in the design and supply of advanced high added-value organic solid-form materials and product composites.

Novel Optical Resolution Technologies

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Publisher : Springer
ISBN 13 : 3540463208
Total Pages : 318 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Novel Optical Resolution Technologies by : Kenichi Sakai

Download or read book Novel Optical Resolution Technologies written by Kenichi Sakai and published by Springer. This book was released on 2007-01-30 with total page 318 pages. Available in PDF, EPUB and Kindle. Book excerpt: With contributions by numerous experts

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Author :
Publisher : IOS Press
ISBN 13 :
Total Pages : 10439 pages
Book Rating : 4./5 ( download)

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Download or read book written by and published by IOS Press. This book was released on with total page 10439 pages. Available in PDF, EPUB and Kindle. Book excerpt:

BIWIC 2007

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Publisher : IOS Press
ISBN 13 : 1586037900
Total Pages : 284 pages
Book Rating : 4.5/5 (86 download)

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Book Synopsis BIWIC 2007 by : Alison Lewis

Download or read book BIWIC 2007 written by Alison Lewis and published by IOS Press. This book was released on 2007 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of crystallization holds many challenges, with the physical and chemical complexity of the crystallization process being core to the dynamic nature of the field. Exciting advances are achieved in the areas of nanoparticle formation, product and particle design and methods of particle characterization.

BIWIC 2007 14th International Workshop on Industrial Crystallization

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Publisher : IOS Press
ISBN 13 : 160750278X
Total Pages : 284 pages
Book Rating : 4.6/5 (75 download)

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Book Synopsis BIWIC 2007 14th International Workshop on Industrial Crystallization by : A.E. Lewis

Download or read book BIWIC 2007 14th International Workshop on Industrial Crystallization written by A.E. Lewis and published by IOS Press. This book was released on 2007-08-31 with total page 284 pages. Available in PDF, EPUB and Kindle. Book excerpt: The field of crystallization holds many challenges, with the physical and chemical complexity of the crystallization process being core to the dynamic nature of the field. Exciting advances are currently being achieved in the areas of nanoparticle formation, product and particle design and methods of particle characterisation. There is also significant progress and innovation in the design, scale-up and control of crystallizers. These key developments are reflected in the session themes of the 14th BIWIC (Bremen International Workshop on Industrial Crystallization) with the technical programme incorporating a wide range of topics, such as; The formation and stabilisation of nano particles; Polymorphs and co-crystals in pharmaceutical preparation; Product and particle design; Kinetics of crystallization and measurement of crystal properties; Freeze, Antisolvent, Reactive and Melt crystallization; and Design, scale-up and control of crystallization processes at the industrial scale.

Handbook of Chiral Chemicals

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Publisher : CRC Press
ISBN 13 : 1420027301
Total Pages : 632 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Handbook of Chiral Chemicals by : David Ager

Download or read book Handbook of Chiral Chemicals written by David Ager and published by CRC Press. This book was released on 2005-10-21 with total page 632 pages. Available in PDF, EPUB and Kindle. Book excerpt: As pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. "The Handbook of Chiral Chemicals, Second Edition" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook fir

Practical Process Research and Development

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Publisher : Academic Press
ISBN 13 : 0123865379
Total Pages : 489 pages
Book Rating : 4.1/5 (238 download)

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Book Synopsis Practical Process Research and Development by : Neal G. Anderson

Download or read book Practical Process Research and Development written by Neal G. Anderson and published by Academic Press. This book was released on 2012-04-09 with total page 489 pages. Available in PDF, EPUB and Kindle. Book excerpt: Designed to provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine chemical, and agricultural chemical industries, this book describes the steps taken, following synthesis and evaluation, to bring key compounds to market in a cost-effective manner. It describes hands-on, step-by-step, approaches to solving process development problems, including route, reagent, and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." Second Edition highlights: . Reflects the current thinking in chemical process R&D for small molecules . Retains similar structure and orientation to the first edition. . Contains approx. 85% new material . Primarily new examples (work-up and prospective considerations for pilot plant and manufacturing scale-up) . Some new/expanded topics (e.g. green chemistry, genotoxins, enzymatic processes) . Replaces the first edition, although the first edition contains useful older examples that readers may refer to Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules" Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more Presents guidelines for implementing and troubleshooting processes

Encyclopedia of Chromatography

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Publisher : CRC Press
ISBN 13 : 1439870675
Total Pages : 2968 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Encyclopedia of Chromatography by : Jack Cazes

Download or read book Encyclopedia of Chromatography written by Jack Cazes and published by CRC Press. This book was released on 2009-10-12 with total page 2968 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised and expanded, this third edition offers illustrative tables and figures to clarify technical points in the articles and provides a valuable, reader-friendly reference for all those who employ chromatographic methods for analysis of complex mixtures of substances. An authoritative source of information, this introductory guide to specific chromatographic techniques and theory discusses the relevant science and technology, offering key references for analyzing specific chemicals and applications in industry and focusing on emerging technologies and uses.

Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition

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Publisher : MDPI
ISBN 13 : 3039362380
Total Pages : 346 pages
Book Rating : 4.0/5 (393 download)

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Book Synopsis Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition by : Maria Elizabeth Tiritan

Download or read book Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition written by Maria Elizabeth Tiritan and published by MDPI. This book was released on 2020-11-13 with total page 346 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities.

Asymmetry in Biological Homochirality

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Publisher : MDPI
ISBN 13 : 3036504427
Total Pages : 102 pages
Book Rating : 4.0/5 (365 download)

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Book Synopsis Asymmetry in Biological Homochirality by : David Hochberg

Download or read book Asymmetry in Biological Homochirality written by David Hochberg and published by MDPI. This book was released on 2021-06-04 with total page 102 pages. Available in PDF, EPUB and Kindle. Book excerpt: Chirality, or handedness, is a fundamental physical characteristic, which spans the length scales ranging from elementary particles to the chiral asymmetry of spiral galaxies. The way in which chirality in chemistry, or molecular handedness, may have emerged in a primitive terrestrial environment, and how it can be triggered, amplified, and transferred, are deeply challenging problems rooted in both fundamental scientific interests and the technological potentials for science and society. Chirality constitutes a unifying feature of the living world and is a prime driving force for molecular selection and genetic evolution in biology. In this book, we offer a selection of five distinct approaches to this problem by leading experts in the field. The selected topics range from protein chirality and its relevance to protein ageing, protein aggregation and neurodegeneration, entropy production associated with chiral symmetry breaking in closed systems, chiral oscillations in polymerization models involving higher-order oligomers, the mirror symmetry breaking in liquids and its implications for the development of homochirality in abiogenesis, the role of chirality in the chemical sciences, and some philosophical implications of chirality.

Pharmaceutical Industry Practices on Genotoxic Impurities

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Publisher : CRC Press
ISBN 13 : 1439874212
Total Pages : 536 pages
Book Rating : 4.4/5 (398 download)

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Book Synopsis Pharmaceutical Industry Practices on Genotoxic Impurities by : Heewon Lee

Download or read book Pharmaceutical Industry Practices on Genotoxic Impurities written by Heewon Lee and published by CRC Press. This book was released on 2014-08-29 with total page 536 pages. Available in PDF, EPUB and Kindle. Book excerpt: A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, methods, interpretati

Practical Synthetic Organic Chemistry

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Publisher : John Wiley & Sons
ISBN 13 : 1119448905
Total Pages : 1560 pages
Book Rating : 4.1/5 (194 download)

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Book Synopsis Practical Synthetic Organic Chemistry by : Stéphane Caron

Download or read book Practical Synthetic Organic Chemistry written by Stéphane Caron and published by John Wiley & Sons. This book was released on 2020-02-06 with total page 1560 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diese Publikation ist ein Praktikerbuch für Organiker. Der Schwerpunkt liegt auf den Reaktionen, die am verlässlichsten und nützlichsten sind. Die Autoren der einzelnen Kapitel stellen Chemiker die Informationen zur Verfügung, die für die strategische Planung einer Synthese und Wiederholung der Verfahren im Labor notwendig sind. - Fasst alle wesentlichen Entwicklungen und Konzepte in einer Publikation zusammen und deckt die meisten der wichtigen Reaktionen in der organischen Chemie ab, u. a. Substitutions-, Additions-, Eliminierungsreaktionen, Umlagerung, Oxidation, Reduktion. - Behandelt die wichtigsten Reaktionen ausführlicher und zeigt die grundlegenden Prinzipien, Vor- und Nachteile der Methoden, Mechanismen und Techniken, um Reaktionen im Labor erfolgreich durchzuführen. - Mit neuen Inhalten zu den jüngsten Fortschritten in den Bereichen CH-Aktivierung, Photoredox-Katalyse und Elektrochemie, kontinuierliche chemische Prozesse und Anwendung der Biokatalyse in der Synthese. - Bietet überarbeitete Kapitel mit neuen und zusätzlichen chemischen Beispielen aus der Praxis.

Organic Syntheses, Collective Volume 12

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Publisher : John Wiley & Sons
ISBN 13 : 1118117824
Total Pages : 1606 pages
Book Rating : 4.1/5 (181 download)

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Book Synopsis Organic Syntheses, Collective Volume 12 by : Charles K. Zercher

Download or read book Organic Syntheses, Collective Volume 12 written by Charles K. Zercher and published by John Wiley & Sons. This book was released on 2015-10-19 with total page 1606 pages. Available in PDF, EPUB and Kindle. Book excerpt: Continuing the tradition of providing significant and interesting procedures, Organic Syntheses, Collective Volume XII is a compilation of revised editions of Annual Volumes 85 through 89. The contents of this volume are organized by primarily by reaction type, with the precise classification made according to the bias of the editor, who attempted to ascertain the primary purpose or utility of the procedure.

Chiral Separation Techniques

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Publisher : John Wiley & Sons
ISBN 13 : 352761172X
Total Pages : 641 pages
Book Rating : 4.5/5 (276 download)

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Book Synopsis Chiral Separation Techniques by : Ganapathy Subramanian

Download or read book Chiral Separation Techniques written by Ganapathy Subramanian and published by John Wiley & Sons. This book was released on 2008-01-08 with total page 641 pages. Available in PDF, EPUB and Kindle. Book excerpt: Thoroughly revised, with either entirely new or completely updated contents, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.

Green Chemistry in the Pharmaceutical Industry

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Publisher : John Wiley & Sons
ISBN 13 : 9783527629695
Total Pages : 388 pages
Book Rating : 4.6/5 (296 download)

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Book Synopsis Green Chemistry in the Pharmaceutical Industry by : Peter J. Dunn

Download or read book Green Chemistry in the Pharmaceutical Industry written by Peter J. Dunn and published by John Wiley & Sons. This book was released on 2010-02-02 with total page 388 pages. Available in PDF, EPUB and Kindle. Book excerpt: Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.