Controversies in the Management of Liver Metastases

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Publisher :
ISBN 13 : 9783805590471
Total Pages : 0 pages
Book Rating : 4.5/5 (94 download)

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Book Synopsis Controversies in the Management of Liver Metastases by : Thomas M. van Gulik

Download or read book Controversies in the Management of Liver Metastases written by Thomas M. van Gulik and published by . This book was released on 2009 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: While considerable progress has been made in both surgical treatment of liver metastases and neoadjuvant or postoperative chemotherapy, decision making has become more complex. The definition of accurate measures is very difficult because there exists no consensus regarding pre- or postoperative predictors of survival in patients undergoing liver resection: Even though PET is well established in the diagnosis of colorectal cancer and its metastases, it is unclear whether a combination of imaging modalities will be of additional value. Neoadjuvant strategies are very efficient in downsizing metastasis, but they at the same time reduce functional liver reserve due to chemotherapy-induced liver injury. The advantages and disadvantages of the 'liver first' approach are likewise discussed, as are controversial issues in the use of portal vein embolization and radiofrequency ablation versus resection. Even though the main focus of this publication is on colorectal liver metastases, other primary cancers also receive some attention: Papers on resection of liver metastases combined with primary cancers conclude the discussions. This collection of papers provides valuable information on the many issues connected with the management of liver metastases, both colorectal and non-colorectal. Surgeons confronted with the question as to the best treatment strategy will find it a very helpful aid in their decision process.

Current Controversies in Cancer Care for the Surgeon

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Publisher : Springer
ISBN 13 : 3319162055
Total Pages : 213 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Current Controversies in Cancer Care for the Surgeon by : Katherine A. Morgan

Download or read book Current Controversies in Cancer Care for the Surgeon written by Katherine A. Morgan and published by Springer. This book was released on 2015-12-31 with total page 213 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, major advances have occurred in the management of the many fields of cancer treatment encountered by the general surgeon. These developments have evolved from improved understanding of disease biology, high level clinical outcomes studies, as well as translational research with new available therapies. These advances have brought major changes to cancer care and have surfaced new dilemmas in clinical decision-making. Modern cancer management requires an understanding of the current status of a diverse array of oncologic diseases. Current Controversies in Cancer Care for the Surgeon provides a comprehensive update on the management of various cancers as interpreted by recognized experts in the field. In addition, each chapter will focus on current controversies and areas of advance. The text is designed to assist the practicing surgeon in achieving optimal management of encountered oncologic problems. Such an inclusive text will be invaluable resource for clinical surgeons, surgeons in training, students and researchers.

Colorectal Cancer Liver Metastases

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Publisher : Springer Nature
ISBN 13 : 3030254860
Total Pages : 597 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Colorectal Cancer Liver Metastases by : Mauro Monteiro Correia

Download or read book Colorectal Cancer Liver Metastases written by Mauro Monteiro Correia and published by Springer Nature. This book was released on 2019-12-28 with total page 597 pages. Available in PDF, EPUB and Kindle. Book excerpt: Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are better understood and more therapeutic and surgical options are developed. Consequently, all professionals involved with the diagnosis, treatment and follow up of CLM should be kept up to date with the latest advances on the field, to provide high standard medical care to their patients. This book is designed to present the state-of-the-art in CLM management and, in doing so, to review the current evidence on CLM, discussing all important topics in the field. Coverage is broad and comprehensive, encompassing introductory topics (history, definitions, epidemiology, etc.), basic science subjects (molecular biology, genetics, dissemination process, etc.) and practical clinical topics (tumor behavior, diagnosis, drug therapy, radiation therapy, surgery, ablation, multidisciplinary teams, etc.). Although comprehensive on the coverage and selection of topics, each chapter is concise and objective, dissecting topics in a practical and direct format. Evidences and recommendations are included. Chapters display a brief introduction of the common knowledge, go straight to the detailed revision of the most recent years of the literature, and end with practical closing observations. This book is a tool for professionals (general and cancer surgeons, HPB surgeons, clinical oncologists, gastroenterologists and medical residents) and interns who search for a qualified and reader friendly revision on topics concerning Colorectal Cancer Liver Metastases.

Functional Imaging in Oncology

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Publisher : Springer
ISBN 13 : 3642405827
Total Pages : 918 pages
Book Rating : 4.6/5 (424 download)

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Book Synopsis Functional Imaging in Oncology by : Antonio Luna

Download or read book Functional Imaging in Oncology written by Antonio Luna and published by Springer. This book was released on 2014-07-08 with total page 918 pages. Available in PDF, EPUB and Kindle. Book excerpt: In the new era of functional and molecular imaging, both currently available imaging biomarkers and biomarkers under development are expected to lead to major changes in the management of oncological patients. This two-volume book is a practical manual on the various imaging techniques capable of delivering functional information on cancer, including diffusion MRI, perfusion CT and MRI, dual-energy CT, spectroscopy, dynamic contrast-enhanced ultrasonography, PET, and hybrid modalities. This second volume considers the applications and benefits of these techniques in a wide range of tumor types, including their role in diagnosis, prediction of treatment outcome, and early evaluation of treatment response. Each chapter addresses a specific malignancy and is written by one or more acclaimed experts. The lucid text is complemented by numerous high-quality illustrations that highlight key features and major teaching points.

Hepato-Pancreato-Biliary and Transplant Surgery

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Publisher : Beaux Books Publishing, LLC
ISBN 13 : 0997772182
Total Pages : 1352 pages
Book Rating : 4.9/5 (977 download)

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Book Synopsis Hepato-Pancreato-Biliary and Transplant Surgery by : Quyen D Chu

Download or read book Hepato-Pancreato-Biliary and Transplant Surgery written by Quyen D Chu and published by Beaux Books Publishing, LLC. This book was released on 2018-01-08 with total page 1352 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique textbook provides a concise and practical approach to clinical dilemmas involving the liver, pancreas, and biliary tree. Six major sections encompass (1) Hepatic, (2) Biliary, (3) Pancreas, (4) Transplantation, (5) Trauma, and (6) Innovative Technology. Each topic is written by recognized experts from an "e;experiential"e; viewpoint combined with evidence-based medicine. The book contains over 170 chapters and over 350 contributors. It is relevant to Surgical Oncologists, Hepato-Pancreato-Biliary (HPB) Surgeons, Transplant Surgeons, Traumatologists, HPB Interventionalists, General Surgeons, and trainees and students. The title of each chapter is in a form of a clinical scenario and each chapter begins with a Case Scenario and ends with Salient Points. Special debates are included in each section. There are numerous compelling images, detailed illustrations, comprehensive tables, thorough algorithms, and other adjunctive tools that enhance learning. The authors emanate from different corners of the world. The book is a valuable resource for faculty, students, surgical trainees, fellows, and all health care providers in the HPB/Trauma/Transplant/Oncology fields.

Cancer: Principles & Practice of Oncology

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Publisher : Lippincott Williams & Wilkins
ISBN 13 : 1451180748
Total Pages : 1494 pages
Book Rating : 4.4/5 (511 download)

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Book Synopsis Cancer: Principles & Practice of Oncology by : Vincent T. DeVita Jr.

Download or read book Cancer: Principles & Practice of Oncology written by Vincent T. DeVita Jr. and published by Lippincott Williams & Wilkins. This book was released on 2012-01-05 with total page 1494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Announcing the second volume of DeVita, Lawrence and Rosenberg's groundbreaking series, Cancer: Principles & Practice of Oncology—Annual Advances in Oncology. This series of annual volumes focuses on the most significant changes in oncologic research and practice that have taken place during the preceding year. Each volume identifies scientific and clinical areas in oncology that are rapidly changing and show a high potential for affecting the management of cancer patients in the future. These areas may reflect current controversies in oncology and every effort is made to provide clear direction for the practicing oncologist.

Preoperative (Neoadjuvant) Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642826717
Total Pages : 172 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Preoperative (Neoadjuvant) Chemotherapy by : Joseph Ragaz

Download or read book Preoperative (Neoadjuvant) Chemotherapy written by Joseph Ragaz and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 172 pages. Available in PDF, EPUB and Kindle. Book excerpt: Despite recent advances in adjuvant therapies of cancer, the regi mens of postoperative adjuvant chemotherapy treatment which are presently available fail to cure the majority of cancer patients. Pre operative (neoadjuvant) chemotherapy represents a new approach in drug scheduling, based on sound theoretical, pharmacokinetic, and experimental principles. The preoperative timing of chemotherapy before definitive sur gery is not a minor change in the therapy of cancer. To be successful, large numbers of practitioners and their patients must participate. Substantial alterations of many aspects of the present management of cancer will have to follow. Therefore, before such therapy can be fully and routinely implemented, results of the novel treatment and its rationale have to be carefully evaluated. In preoperative treatment, other features will likely gain impor tance. For the first time, clinicians have a chance to follow the in vivo response of the tumor exposed to preoperative chemotherapy. The subsequent histological assessment of the tumor sample may likely become an important prognostic guide, permitting more re fined individual approaches to the planning of postoperative adju vant treatment. The value of such a treatment strategy can already be appreciated in the clinical setting, as seen from the therapy of osteosarcoma. Furthermore, preoperative chemotherapy might render previously inoperable tumors operable and hence resectable with a curative intention. The preoperative reduction of tumor bulk may also effectively decrease the need for more radical operations, permitting a more uniform adoption of conservative surgery.

Liver Metastasis: Biology and Clinical Management

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Publisher : Springer Science & Business Media
ISBN 13 : 9400702922
Total Pages : 447 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Liver Metastasis: Biology and Clinical Management by : Pnina Brodt

Download or read book Liver Metastasis: Biology and Clinical Management written by Pnina Brodt and published by Springer Science & Business Media. This book was released on 2011-03-01 with total page 447 pages. Available in PDF, EPUB and Kindle. Book excerpt: Liver metastases are a frequent and often fatal occurrence in cancer patients, particularly those with malignancies of the gastrointestinal (GI) tract. While recent improvements in surgical techniques and a more aggressive approach to resection of liver metastases have improved long term survival for some patients, most patients with hepatic metastases still succumb to their disease. To improve these dismal statistics, a better understanding of the biology of liver metastasis, particularly the early stages that can be targeted for prevention, is essential. Once cancer cells enter the liver, several different scenarios may occur. The cancer cells may be immediately destroyed by local defence mechanisms, they may enter a state of dormancy as solitary cells and never produce a metastasis, initiate a short-lived process of proliferation that is aborted before a metastasis is established or actively proliferate to form macrometastases. The chapters in Part I of this book provide insight into the cellular/molecular mechanisms that determine which of these scenarios prevails. Written by experts researchers in the filed of metastasis, these chapters provide state-of-the art reviews on the cellular and molecular processes that impact the early stages of the metastatic process. The unique microenvironment of the liver, its various anatomical, cellular and molecular features and the impact they have on metastasis are highlighted. In addition, the role of inflammation (pre-existing and tumor-induced), host innate and adaptive immune responses, cytokines, chemokines, growth factors and the unique molecular signatures of metastatic tumor cells are reviewed with an underscoring of the translational implications of the current state of knowledge. Against this background, the chapters in Part II of the book provide critical reviews on major aspects of the clinical management of hepatic metastases. These include imaging strategies, surgical and chemotherapeutic treatment approaches and the use of targeted biological therapeutics such as anti-angiogenic drugs as treatment modalities. By combining information on biological and clinical aspects of liver metastasis, this volume will serve as an excellent resource for scientists, clinicians, clinician/ scientists and trainees in the domains of oncology, surgical oncology, hepatobiliary physiology and radiology.

Radiation Therapy for Gastrointestinal Cancers

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Publisher : Springer
ISBN 13 : 3319431153
Total Pages : 245 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Radiation Therapy for Gastrointestinal Cancers by : Theodore Hong

Download or read book Radiation Therapy for Gastrointestinal Cancers written by Theodore Hong and published by Springer. This book was released on 2017-02-13 with total page 245 pages. Available in PDF, EPUB and Kindle. Book excerpt: This up-to-date, hands-on manual offers clear guidance on contouring and treatment planning for both standard and advanced radiation therapy in patients with gastrointestinal cancers and simultaneously draws together the available relevant clinical data for each type of cancer with a view to driving treatment recommendations. The full range of malignancies is covered, including esophageal, gastric, pancreatic, hepatic, biliary, colon, rectal, and anal cancers and pelvic recurrences. Additional chapters are devoted to stereotactic body radiation therapy (SBRT) to the liver for metastatic disease. The management of gastrointestinal cancers with radiation therapy has become increasingly complex. Specifically, the emergence of new techniques such as SBRT and intensity-modulated radiation therapy (IMRT) has further increased the need to understand how to contour targets and organs at risk, how to perform safe treatment planning, and when to apply these technologies. In this context, Radiation Therapy for Gastrointestinal Cancers represents an ideal reference for both established clinical radiation oncologists and radiation oncology residents.

The ASCRS Textbook of Colon and Rectal Surgery

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Publisher : Springer
ISBN 13 : 3319259709
Total Pages : 1269 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis The ASCRS Textbook of Colon and Rectal Surgery by : Scott R. Steele

Download or read book The ASCRS Textbook of Colon and Rectal Surgery written by Scott R. Steele and published by Springer. This book was released on 2016-03-24 with total page 1269 pages. Available in PDF, EPUB and Kindle. Book excerpt: This third edition text provides a completely revised and updated new version of this unique, modern, practical text that covers the strategic evaluation, specific approaches, and detailed management techniques utilized by expert colorectal surgeons caring for patients with complex problems–whether they result from underlying colorectal disease or from complications arising from previous surgical therapy. The format follows that of both a “how to” manual as well as an algorithm-based guide to allow the reader to understand the thought process behind the proposed treatment strategy. By making use of evidence-based recommendations, each chapter includes not only background information and diagnostic/therapeutic guidelines, but also provides a narrative by the author on his/her operative technical details and perioperative “tips and tricks” that they utilize in the management of these complex surgical challenges. Distinctive to this book, is the reliance on experts in the field including past presidents of the ASCRS, as well as multiple other national and internationally recognized surgeons, to lend their personal insight into situations where data may be more sparse, but individual and collective experience is paramount to making sound decisions and thereby optimizing patient outcomes. The text includes chapters on the assessment of risk and methods utilized to minimize perioperative complications. In addition, it incorporates sections covering the medical and surgical therapies for abdominal, pelvic and anorectal disease. Moreover, the technical challenges of managing complications resulting from the original or subsequent operations is addressed. The underlying focus throughout the text is on providing pragmatic and understandable solutions that can be readily implemented by surgeons of varying experience to successfully treat complex colorectal problems. However, it also goes beyond the technical aspects of colorectal surgery and includes special sections highlighting the essence of a surgeon; covering aspects involving the medical-legal, ethical, and economic challenges confronting surgeons. Throughout the text, each author provides an ongoing narrative of his/her individual surgical techniques along with illustrations and diagrams to “personally” take the reader through the crucial steps of the procedure, and key points of patient care inherent to that topic. Additionally, where appropriate, links to online videos give the reader an up-front look into technical aspects of colorectal surgery.

Liver Disease and Surgery

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Publisher : BoD – Books on Demand
ISBN 13 : 1789850657
Total Pages : 250 pages
Book Rating : 4.7/5 (898 download)

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Book Synopsis Liver Disease and Surgery by : Georgios Tsoulfas

Download or read book Liver Disease and Surgery written by Georgios Tsoulfas and published by BoD – Books on Demand. This book was released on 2019-11-27 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: The goal of this book is to present a review of the different categories of liver disease, as well as address the role of surgery in managing these complex diseases. The book includes chapters written by international experts on the most current indications and guidelines regarding the diagnoses and management of liver diseases, as well as a variety of technical elements involved with the surgical procedures. Different surgical techniques involved in performing a hepatectomy will be discussed, including various instruments used, as well as the effect of modern technology as evidenced by novel procedures. An important focus of the book has been identifying the proper place of all these hepatectomy methods in the armamentarium of the experienced hepatobiliary surgeon, including the role of locoregional treatments such as ablation and embolization as adjuncts. Finally, the role of hepatectomy compared to orthotopic liver transplantation is discussed, so that the reader can have a well-rounded picture of the challenges and opportunities involved. Overall, this book has the potential to serve as an invaluable "tool" for both the hepatologist and the internist, as well as for the hepatic surgeon

Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery

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Publisher : Springer
ISBN 13 : 3319508687
Total Pages : 461 pages
Book Rating : 4.3/5 (195 download)

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Book Synopsis Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery by : Timothy M. Pawlik

Download or read book Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery written by Timothy M. Pawlik and published by Springer. This book was released on 2017-03-18 with total page 461 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text provides a comprehensive, state-of-the art definitive “case-based” reference for the work-up, diagnosis, intraoperative management, and peri-operative care of patients with complex, difficult to manage HPB diseases. The book provides a practical, clinically useful guide that reviews select complicated HPB cases, as well as providing key information on how to manage such patients. This text provides detailed “case-based” algorithms, as well as specific guidance on the management of complicated HPB patients. In addition, it also focuses on key points on how to work-up patients pre-operatively, highlights intra-operative technical “pearls”, and defines optimal post-operative care. Chapters are rich with images, have multiple “call out” boxes to highlight key lessons learned and also include clinical management “pearls.” All chapters are written by experts in their field and include the most up-to-date clinical information from national and world leaders in their respective discipline. Case-Based Lessons in the Management of Complex Hepato-Pancreato-Biliary Surgery will serve as a very useful resource for physicians, fellows and residents dealing with complex HPB patients. In addition, It will provide a concise yet comprehensive summary of the diagnosis, work-up, and management of some of the most complex, yet common, HPB cases.

Perioperative Chemotherapy

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Publisher : Springer Science & Business Media
ISBN 13 : 3642824323
Total Pages : 170 pages
Book Rating : 4.6/5 (428 download)

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Book Synopsis Perioperative Chemotherapy by : U. Metzger

Download or read book Perioperative Chemotherapy written by U. Metzger and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 170 pages. Available in PDF, EPUB and Kindle. Book excerpt: One reason for failure to cure solid tumors by surgery appears to be the impossibility of controlling metastases that are present but latent at the time of operation. This failure is a common clinical experience with aggressive neoplasms. but it is not always appreciated in tumors with longer survival times. e. g .• breast and colon cancer. In addition. recent evidence indicates that after resection of a primary tumor micrometas tases from it might be enhanced by suppression of immune and reticu loendothelial functions of the host. Other factors, such as increase of coagulability and stress in the perioperative period, can also promote tumor growth. The development of new metastases might be facilitated by cells forced into the circulation during operative manipulations. Such events could be important for the outcome of treatment and it is suggested that preventive measures should be directed to this systemic component of solid tumors. Radical surgery can reduce the number of tumor cells to a subclinical 3 6 stage (10 to 10 cells) in which chemotherapy might be more effective than in advanced stages. Chemotherapy, on the other hand, might aggravate the surgical morbidity by influencing the wound healing pro cess, by decreasing the immune response, and/or by toxicity to the bone marrow and to the gastrointestinal tract, for example.

NIH state-of-the-science statement on management of the clinically inapparent adrenal mass ("incidentaloma").

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Author :
Publisher :
ISBN 13 :
Total Pages : 32 pages
Book Rating : 4.:/5 (318 download)

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Book Synopsis NIH state-of-the-science statement on management of the clinically inapparent adrenal mass ("incidentaloma"). by :

Download or read book NIH state-of-the-science statement on management of the clinically inapparent adrenal mass ("incidentaloma"). written by and published by . This book was released on 2002 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Liver Malignancies

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Publisher : Springer Science & Business Media
ISBN 13 : 3642586414
Total Pages : 534 pages
Book Rating : 4.6/5 (425 download)

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Book Synopsis Liver Malignancies by : C. Bartolozzi

Download or read book Liver Malignancies written by C. Bartolozzi and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 534 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive and up-to-date overview of the role of diagnostic and interventional radiology in respect of liver malignancies. Following background chapters on anatomy, epidemiology, and clinicopathologic features, each of the diagnostic imaging techniques is carefully appraised, focusing on new developments in equipment and contrast agents. The interventional therapeutic approaches to primary and secondary hepatic malignancies are then discussed in depth, as well as such special topics as liver tumors in children and hepatic transplantation. Written by leading experts from around the world, this will prove to be an indispensable source of information for both clinicians and researchers.

Neuroendocrine Tumors: A Multidisciplinary Approach

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Publisher : Karger Medical and Scientific Publishers
ISBN 13 : 3318027731
Total Pages : 282 pages
Book Rating : 4.3/5 (18 download)

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Book Synopsis Neuroendocrine Tumors: A Multidisciplinary Approach by : M. Papotti

Download or read book Neuroendocrine Tumors: A Multidisciplinary Approach written by M. Papotti and published by Karger Medical and Scientific Publishers. This book was released on 2015-08-11 with total page 282 pages. Available in PDF, EPUB and Kindle. Book excerpt: The term ‘carcinoid’ entered medical literature over 100 years ago to describe a peculiar intestinal epithelial neoplasm. Since then, a large body of literature has expanded the concept of carcinoid, later replaced by the term ‘NeuroEndocrine Tumor’ (NET), defining a wide spectrum of peculiar tumors, potentially affecting all organs and tissues, originating from neuroendocrine cells, sharing, but, at the same time, keeping, pathognomonic pathological, radiological and clinical features. This book provides an authoritative overview of the epidemiological, clinical, genetic, molecular and pathological characteristics of NETs and highlights the most relevant controversial issues in the classification, diagnosis and therapy. Furthermore the new frontiers in the field of medical therapies are presented, through a multidisciplinary and translational approach. Considering the fact that NETs have been recently demonstrated less rare as considered so far, 'Neuroendocrine Tumors: A Multidisciplinary Approach' is a must read for endocrinologists, gastroenterologists, endocrine surgeons, as well as pathologists, nuclear medicine physicians and radiologists focused on NET.

Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease

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Author :
Publisher : World Scientific Publishing Company
ISBN 13 : 9814583030
Total Pages : 672 pages
Book Rating : 4.8/5 (145 download)

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Book Synopsis Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease by : Dan G Blazer III

Download or read book Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease written by Dan G Blazer III and published by World Scientific Publishing Company. This book was released on 2013-11-01 with total page 672 pages. Available in PDF, EPUB and Kindle. Book excerpt: Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Diseases presents an excellent resource for surgical residents, hepatobiliary fellows and practicing surgeons interested in hepatobiliary surgery. This textbook offers a readable, concise and practical alternative. It is divided into three sections: liver, biliary tract, and pancreatic diseases. Each section covers the spectrum of benign and malignant disease. In addition, several chapters in each section are devoted to surgical techniques. This textbook should ultimately serve as an essential source for the rapidly evolving field of hepatobiliary surgery and its practitioners.