The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Publisher : John Wiley & Sons
ISBN 13 : 1118503678
Total Pages : 514 pages
Book Rating : 4.1/5 (185 download)

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Book Synopsis The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by : Andre S. Merbach

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by Andre S. Merbach and published by John Wiley & Sons. This book was released on 2013-02-19 with total page 514 pages. Available in PDF, EPUB and Kindle. Book excerpt: Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

Contrast Agents I

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Author :
Publisher : Springer
ISBN 13 : 354045733X
Total Pages : 251 pages
Book Rating : 4.5/5 (44 download)

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Book Synopsis Contrast Agents I by : Werner Krause

Download or read book Contrast Agents I written by Werner Krause and published by Springer. This book was released on 2003-07-01 with total page 251 pages. Available in PDF, EPUB and Kindle. Book excerpt: Extracellular MRI and X-ray contrast agents are characterized by their phar- cokinetic behaviour.After intravascular injection their plasma-level time curve is characeterized by two phases. The agents are rapidly distributed between plasma and interstitial spaces followed by renal elimination with a terminal half-live of approximatly 1–2 hours. They are excreted via the kidneys in unchanged form by glomerular filtration. Extracellular water-soluble contrast agents to be applied for X-ray imaging were introduced into clinical practice in 1923. Since that time they have proved to be most valuable tools in diagnostics.They contain iodine as the element of choice with a sufficiently high atomic weight difference to organic tissue. As positive contrast agents their attenuation of radiation is higher compared with the attenuation of the surrounding tissue. By this contrast enhancement X-ray diagnostics could be improved dramatically. In 2,4,6-triiodobenzoic acid derivatives iodine is firmly bound. Nowadays diamides of the 2,4,6-triiodo-5-acylamino-isophthalic acid like iopromide (Ultravist, Fig. 1) are used as non-ionic (neutral) X-ray contrast agents in most cases [1].

Electron Paramagnetic Resonance Spectroscopy

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Author :
Publisher : Springer Nature
ISBN 13 : 3030396630
Total Pages : 420 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Electron Paramagnetic Resonance Spectroscopy by : Patrick Bertrand

Download or read book Electron Paramagnetic Resonance Spectroscopy written by Patrick Bertrand and published by Springer Nature. This book was released on 2020-02-03 with total page 420 pages. Available in PDF, EPUB and Kindle. Book excerpt: Although originally invented and employed by physicists, electron paramagnetic resonance (EPR) spectroscopy has proven to be a very efficient technique for studying a wide range of phenomena in many fields, such as chemistry, biochemistry, geology, archaeology, medicine, biotechnology, and environmental sciences. Acknowledging that not all studies require the same level of understanding of this technique, this book thus provides a practical treatise clearly oriented toward applications, which should be useful to students and researchers of various levels and disciplines. In this book, the principles of continuous wave EPR spectroscopy are progressively, but rigorously, introduced, with emphasis on interpretation of the collected spectra. Each chapter is followed by a section highlighting important points for applications, together with exercises solved at the end of the book. A glossary defines the main terms used in the book, and particular topics, whose knowledge is not required for understanding the main text, are developed in appendices for more inquisitive readers.

Medical Imaging Contrast Agents: A Clinical Manual

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Author :
Publisher : Springer Nature
ISBN 13 : 3030792560
Total Pages : 303 pages
Book Rating : 4.0/5 (37 download)

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Book Synopsis Medical Imaging Contrast Agents: A Clinical Manual by : Sukru Mehmet Erturk

Download or read book Medical Imaging Contrast Agents: A Clinical Manual written by Sukru Mehmet Erturk and published by Springer Nature. This book was released on 2021-08-24 with total page 303 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume highlights and broadens our understanding of the correct use and the possible contraindications of contrast agents applied in radiology. Written by experts in the field, it not only focuses on the chemistry, physiochemical properties and pharmacokinetics of both iodinated and gadolinium-containing contrast agents, but also on the relevant safety issues such as frequency of their short- and long-term side effects and ways to avoid them nephrotoxicity risk related to the iodinated contrast agents NSF (nephrogenic systemic fibrosis) accumulation of gadolinium in the brain use of contrast agents in pediatric patients and pregnancy It also includes essential data on the use of contrast agents, such as scanning protocols, in the context of various clinical conditions. This comprehensive manual addresses all professionals involved in radiological imaging and is an invaluable tool for radiologists and technologists, as well as for residents and clinicians.

MR Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 1455749788
Total Pages : 223 pages
Book Rating : 4.4/5 (557 download)

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Book Synopsis MR Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics by : Marco Essig

Download or read book MR Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics written by Marco Essig and published by Elsevier Health Sciences. This book was released on 2012-11-28 with total page 223 pages. Available in PDF, EPUB and Kindle. Book excerpt: MRI contrast agents improve visibility of internal body structures. This issue offers a complete, practically focused review of the use of a variety of contrast agents for MR Imaging. A contrast agent not only must be safe, but also efficacious and cost-effective, and the articles in this issue address all three of these concerns and the uses of contrast agents for a variety of applications.

Update on Imaging Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics of North America, E-Book

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Author :
Publisher : Elsevier Health Sciences
ISBN 13 : 0323548881
Total Pages : pages
Book Rating : 4.3/5 (235 download)

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Book Synopsis Update on Imaging Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics of North America, E-Book by : Carlos A. Zamora

Download or read book Update on Imaging Contrast Agents, An Issue of Magnetic Resonance Imaging Clinics of North America, E-Book written by Carlos A. Zamora and published by Elsevier Health Sciences. This book was released on 2017-10-11 with total page pages. Available in PDF, EPUB and Kindle. Book excerpt: This issue of MRI Clinics of North America focuses on Update on Imaging Contrast Agents, and is edited by Drs. Carlos Zamora, Mauricio Castillo, Richard Semelka. Articles will include: Historical Perspective of Imaging Contrast Agents; Current Radiographic Iodinated Contrast Agents; Contrast-enhanced Sonography; Myelography: From Lipid-based to Gadolinium-based Contrast Agents; Acute Allergic Reactions with Gadolinium-based Contrast Agents: Diagnosis and Treatment; Deposition and Chronic Toxicity of Gadolinium-based Contrast Agents; Managing Allergic Reactions to Contrast Agents; Safety of Contrast Material Use in Children; Molecular Imaging and Contrast Agents; Contrast Agents for MR Imaging: Gadolinium, Manganese, SPIO, Superparamagnetic Iron Platinum, and Oral Agents; Contrast-induced Nephropathy: Pathophysiology, Manifestations, Prevention, and Management; and more!

Essential Radiology Review

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Publisher : Springer Nature
ISBN 13 : 3030260445
Total Pages : 545 pages
Book Rating : 4.0/5 (32 download)

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Book Synopsis Essential Radiology Review by : Adam E. M. Eltorai

Download or read book Essential Radiology Review written by Adam E. M. Eltorai and published by Springer Nature. This book was released on 2019-12-18 with total page 545 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is an on-the-spot reference for residents and medical students seeking diagnostic radiology fast facts. Its question-and-answer format makes it a perfect quick-reference for personal review and studying for board examinations and re-certification. Readers can read the text from cover to cover to gain a general foundation of knowledge that can be built upon through practice or can use choice chapters to review a specific subspecialty before starting a new rotation or joining a new service. With hundreds of high-yield questions and answer items, this resource addresses both general and subspecialty topics and provides accurate, on-the-spot answers. Sections are organized by subspecialty and body area, including chest, abdomen, and trauma, and chapters cover the anatomy, pathophysiology, differential diagnosis, hallmark signs, and image features of major diseases and conditions. Key example images and illustrations enhance the text throughout and provide an ideal, pocket-sized resource for residents and medical students.

Cardiovascular Magnetic Resonance Imaging

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Author :
Publisher : Springer
ISBN 13 : 1493988417
Total Pages : 473 pages
Book Rating : 4.4/5 (939 download)

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Book Synopsis Cardiovascular Magnetic Resonance Imaging by : Raymond Y. Kwong

Download or read book Cardiovascular Magnetic Resonance Imaging written by Raymond Y. Kwong and published by Springer. This book was released on 2019-01-31 with total page 473 pages. Available in PDF, EPUB and Kindle. Book excerpt: The significantly updated second edition of this important work provides an up-to-date and comprehensive overview of cardiovascular magnetic resonance imaging (CMR), a rapidly evolving tool for diagnosis and intervention of cardiovascular disease. New and updated chapters focus on recent applications of CMR such as electrophysiological ablative treatment of arrhythmias, targeted molecular MRI, and T1 mapping methods. The book presents a state-of-the-art compilation of expert contributions to the field, each examining normal and pathologic anatomy of the cardiovascular system as assessed by magnetic resonance imaging. Functional techniques such as myocardial perfusion imaging and assessment of flow velocity are emphasized, along with the exciting areas of artherosclerosis plaque imaging and targeted MRI. This cutting-edge volume represents a multi-disciplinary approach to the field, with contributions from experts in cardiology, radiology, physics, engineering, physiology and biochemistry, and offers new directions in noninvasive imaging. The Second Edition of Cardiovascular Magnetic Resonance Imaging is an essential resource for cardiologists and radiologists striving to lead the way into the future of this important field.

Contrast Media

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Publisher : Springer Science & Business Media
ISBN 13 : 3540727833
Total Pages : 240 pages
Book Rating : 4.5/5 (47 download)

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Book Synopsis Contrast Media by : Henrik S. Thomsen

Download or read book Contrast Media written by Henrik S. Thomsen and published by Springer Science & Business Media. This book was released on 2009-03-23 with total page 240 pages. Available in PDF, EPUB and Kindle. Book excerpt: This revised edition of Contrast Media: Safety Issues and Guidelines, updates the successful first edition and contains new chapters. It provides an invaluable, unique and unparalleled source of information on the safety issues relating to contrast media.

Magnetic Nanoparticles in Biosensing and Medicine

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Publisher : Cambridge University Press
ISBN 13 : 1107031095
Total Pages : 317 pages
Book Rating : 4.1/5 (7 download)

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Book Synopsis Magnetic Nanoparticles in Biosensing and Medicine by : Nicholas J. Darton

Download or read book Magnetic Nanoparticles in Biosensing and Medicine written by Nicholas J. Darton and published by Cambridge University Press. This book was released on 2019-02-14 with total page 317 pages. Available in PDF, EPUB and Kindle. Book excerpt: Drawing together topics from a wide range of disciplines, and featuring up-to-date examples of clinical usage and research applications, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine.

Fluorine Magnetic Resonance Imaging

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Author :
Publisher : CRC Press
ISBN 13 : 9814745324
Total Pages : 462 pages
Book Rating : 4.8/5 (147 download)

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Book Synopsis Fluorine Magnetic Resonance Imaging by : Ulrich Flogel

Download or read book Fluorine Magnetic Resonance Imaging written by Ulrich Flogel and published by CRC Press. This book was released on 2016-10-26 with total page 462 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past decade, fluorine (19F) magnetic resonance imaging (MRI) has garnered significant scientific interest in the biomedical research community owing to the unique properties of fluorinated materials and the 19F nucleus. Fluorine has an intrinsically sensitive nucleus for MRI. There is negligible endogenous 19F in the body and thus there is no background signal. Fluorine-containing compounds are ideal tracer labels for a wide variety of MRI applications. Moreover, the chemical shift and nuclear relaxation rate can be made responsive to physiology via creative molecular design. This book is an interdisciplinary compendium that details cutting-edge science and medical research in the emerging field of 19F MRI. Edited by Ulrich Flögel and Eric Ahrens, two prominent MRI researchers, this book will appeal to investigators involved in MRI, biomedicine, immunology, pharmacology, probe chemistry, and imaging physics.

Contrast Agents in Magnetic Resonance Imaging

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Publisher :
ISBN 13 : 9781904536413
Total Pages : 506 pages
Book Rating : 4.5/5 (364 download)

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Book Synopsis Contrast Agents in Magnetic Resonance Imaging by : Reza Arshady

Download or read book Contrast Agents in Magnetic Resonance Imaging written by Reza Arshady and published by . This book was released on 2009-09 with total page 506 pages. Available in PDF, EPUB and Kindle. Book excerpt: This is a comprehensive treatise on the chemistry, physics and imaging applications of practically all types of contrast agents used in magnetic resonance imaging (MRI).

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

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Author :
Publisher : Wiley
ISBN 13 : 9780471607786
Total Pages : 0 pages
Book Rating : 4.6/5 (77 download)

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Book Synopsis The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging by : André E. Merbach

Download or read book The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging written by André E. Merbach and published by Wiley. This book was released on 2001-04-09 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: There has been a huge increase in the use of MRI and contrast agents in medicine in recent years as evidenced by a big increase in the number of hospitals with MRI machines and the ever-increasing number of examinations using contrast agents. Contrast agents have revolutionized the use of Magnetic Resonance Imaging (MRI) in medical diagnostics, allowing doctors to distinguish between normal and abnormal tissues and ultimately improving prognosis for the patient. This monograph covers all aspects of production, use, operating mechanisms and theory of these diagnostic agents, used to produce high contrast images in MRI. It will therefore be unique resource for what is currently a very active domain of research both in universities and in industry. The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging is a comprehensive treatise: * written by the most active scientists in the field of contrast agents for medical MRI - from both university and industrial backgrounds * covering the topic from every angle from synthesis to safety considerations * invaluable to physicists, chemists, biologists as well as physicians * the first in-depth coverage of this topic

Magnetic Resonance Imaging

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Author :
Publisher : John Wiley & Sons
ISBN 13 : 0471720852
Total Pages : 976 pages
Book Rating : 4.4/5 (717 download)

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Book Synopsis Magnetic Resonance Imaging by : Robert W. Brown

Download or read book Magnetic Resonance Imaging written by Robert W. Brown and published by John Wiley & Sons. This book was released on 2014-06-23 with total page 976 pages. Available in PDF, EPUB and Kindle. Book excerpt: New edition explores contemporary MRI principles and practices Thoroughly revised, updated and expanded, the second edition of Magnetic Resonance Imaging: Physical Principles and Sequence Design remains the preeminent text in its field. Using consistent nomenclature and mathematical notations throughout all the chapters, this new edition carefully explains the physical principles of magnetic resonance imaging design and implementation. In addition, detailed figures and MR images enable readers to better grasp core concepts, methods, and applications. Magnetic Resonance Imaging, Second Edition begins with an introduction to fundamental principles, with coverage of magnetization, relaxation, quantum mechanics, signal detection and acquisition, Fourier imaging, image reconstruction, contrast, signal, and noise. The second part of the text explores MRI methods and applications, including fast imaging, water-fat separation, steady state gradient echo imaging, echo planar imaging, diffusion-weighted imaging, and induced magnetism. Lastly, the text discusses important hardware issues and parallel imaging. Readers familiar with the first edition will find much new material, including: New chapter dedicated to parallel imaging New sections examining off-resonance excitation principles, contrast optimization in fast steady-state incoherent imaging, and efficient lower-dimension analogues for discrete Fourier transforms in echo planar imaging applications Enhanced sections pertaining to Fourier transforms, filter effects on image resolution, and Bloch equation solutions when both rf pulse and slice select gradient fields are present Valuable improvements throughout with respect to equations, formulas, and text New and updated problems to test further the readers' grasp of core concepts Three appendices at the end of the text offer review material for basic electromagnetism and statistics as well as a list of acquisition parameters for the images in the book. Acclaimed by both students and instructors, the second edition of Magnetic Resonance Imaging offers the most comprehensive and approachable introduction to the physics and the applications of magnetic resonance imaging.

Contrast Agents for MRI

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Author :
Publisher : Royal Society of Chemistry
ISBN 13 : 1788012542
Total Pages : 612 pages
Book Rating : 4.7/5 (88 download)

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Book Synopsis Contrast Agents for MRI by : Valérie C Pierre

Download or read book Contrast Agents for MRI written by Valérie C Pierre and published by Royal Society of Chemistry. This book was released on 2017-11-09 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt: As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.

Medical Imaging for Health Professionals

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Publisher : John Wiley & Sons
ISBN 13 : 1119120284
Total Pages : 552 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Medical Imaging for Health Professionals by : Raymond M. Reilly

Download or read book Medical Imaging for Health Professionals written by Raymond M. Reilly and published by John Wiley & Sons. This book was released on 2019-02-06 with total page 552 pages. Available in PDF, EPUB and Kindle. Book excerpt: Describes the most common imaging technologies and their diagnostic applications so that pharmacists and other health professionals, as well as imaging researchers, can understand and interpret medical imaging science This book guides pharmacists and other health professionals and researchers to understand and interpret medical imaging. Divided into two sections, it covers both fundamental principles and clinical applications. It describes the most common imaging technologies and their use to diagnose diseases. In addition, the authors introduce the emerging role of molecular imaging including PET in the diagnosis of cancer and to assess the effectiveness of cancer treatments. The book features many illustrations and discusses many patient case examples. Medical Imaging for Health Professionals: Technologies and Clinical Applications offers in-depth chapters explaining the basic principles of: X-Ray, CT, and Mammography Technology; Nuclear Medicine Imaging Technology; Radionuclide Production and Radiopharmaceuticals; Magnetic Resonance Imaging (MRI) Technology; and Ultrasound Imaging Technology. It also provides chapters written by expert radiologists in well-explained terminology discussing clinical applications including: Cardiac Imaging; Lung Imaging; Breast Imaging; Endocrine Gland Imaging; Abdominal Imaging; Genitourinary Tract Imaging; Imaging of the Head, Neck, Spine and Brain; Musculoskeletal Imaging; and Molecular Imaging with Positron Emission Tomography (PET). Teaches pharmacists, health professionals, and researchers the basics of medical imaging technology Introduces all of the customary imaging tools—X-ray, CT, ultrasound, MRI, SPECT, and PET—and describes their diagnostic applications Explains how molecular imaging aids in cancer diagnosis and in assessing the effectiveness of cancer treatments Includes many case examples of imaging applications for diagnosing common diseases Medical Imaging for Health Professionals: Technologies and Clinical Applications is an important resource for pharmacists, nurses, physiotherapists, respiratory therapists, occupational therapists, radiological or nuclear medicine technologists, health physicists, radiotherapists, as well as researchers in the imaging field.

MRI Contrast Agents

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Author :
Publisher : Springer
ISBN 13 : 9811025290
Total Pages : 128 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis MRI Contrast Agents by : Sophie Laurent

Download or read book MRI Contrast Agents written by Sophie Laurent and published by Springer. This book was released on 2016-11-03 with total page 128 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book describes the multiple aspects of (i) preparation of the magnetic core, (ii) the stabilization with different coatings, (iii) the physico-chemical characterization and (iv) the vectorization to obtain specific nanosystems. Several bio-applications are also presented in this book. In the early days of Magnetic Resonance Imaging (MRI), paramagnetic ions were proposed as contrast agents to enhance the diagnostic quality of MR images. Since then, academic and industrial efforts have been devoted to the development of new and more efficient molecular, supramolecular and nanoparticular systems. Old concepts and theories, like paramagnetic relaxation, were revisited and exploited, leading to new scientific tracks. With their high relaxivity payload, the superparamagnetic nanoparticles are very appealing in the context of molecular imaging but challenges are still numerous: absence of toxicity, specificity, ability to cross the biological barriers, etc.