Computational Systems Neurobiology

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Computational Systems Neurobiology

Author : N. Le Novère
Publisher : Springer Science & Business Media
ISBN 13 : 9400738587
Total Pages : 569 pages
Book Rating : 4.4/5 (7 download)

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Book Synopsis Computational Systems Neurobiology by : N. Le Novère

Download or read book Computational Systems Neurobiology written by N. Le Novère and published by Springer Science & Business Media. This book was released on 2012-07-20 with total page 569 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neurosciences and systems biology are among the main domains of life science research where mathematical modeling made a difference. This book introduces the many different types of computational studies one can develop to study neuronal systems. It is aimed at undergraduate students starting their research in computational neurobiology or more senior researchers who would like, or need, to move towards computational approaches. Based on their specific project, the readers would then move to one of the more specialized excellent textbooks available in the field. The first part of the book deals with molecular systems biology. Functional genomics is introduced through examples of transcriptomics and proteomics studies of neurobiological interest. Quantitative modelling of biochemical systems is presented in homogeneous compartments and using spatial descriptions. A second part deals with the various approaches to model single neuron physiology, and naturally moves to neuronal networks. A division is focused on the development of neurons and neuronal systems and the book closes on a series of methodological chapters. From the molecules to the organ, thinking at the level of systems is transforming biology and its impact on society. This book will help the reader to hop on the train directly in the tank engine.

The Computational Neurobiology of Reaching and Pointing

Author : Reza Shadmehr
Publisher : MIT Press
ISBN 13 : 9780262195089
Total Pages : 608 pages
Book Rating : 4.1/5 (95 download)

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Book Synopsis The Computational Neurobiology of Reaching and Pointing by : Reza Shadmehr

Download or read book The Computational Neurobiology of Reaching and Pointing written by Reza Shadmehr and published by MIT Press. This book was released on 2004-10-28 with total page 608 pages. Available in PDF, EPUB and Kindle. Book excerpt: An introduction to the computational biology of reaching and pointing, with an emphasis on motor learning. Neuroscience involves the study of the nervous system, and its topics range from genetics to inferential reasoning. At its heart, however, lies a search for understanding how the environment affects the nervous system and how the nervous system, in turn, empowers us to interact with and alter our environment. This empowerment requires motor learning. The Computational Neurobiology of Reaching and Pointing addresses the neural mechanisms of one important form of motor learning. The authors integrate material from the computational, behavioral, and neural sciences of motor control that is not available in any other single source. The result is a unified, comprehensive model of reaching and pointing. The book is intended to be used as a text by graduate students in both neuroscience and bioengineering and as a reference source by experts in neuroscience, robotics, and other disciplines. The book begins with an overview of the evolution, anatomy, and physiology of the motor system, including the mechanisms for generating force and maintaining limb stability. The sections that follow, "Computing Locations and Displacements", "Skills, Adaptations, and Trajectories", and "Predictions, Decisions, and Flexibility", present a theory of sensorially guided reaching and pointing that evolves organically based on computational principles rather than a traditional structure-by-structure approach. The book also includes five appendixes that provide brief refreshers on fundamentals of biology, mathematics, physics, and neurophysiology, as well as a glossary of relevant terms. The authors have also made supplemental materials available on the Internet. These web documents provide source code for simulations, step-by-step derivations of certain mathematical formulations, and expanded explanations of some concepts.

Dynamical Systems in Neuroscience

Author : Eugene M. Izhikevich
Publisher : MIT Press
ISBN 13 : 0262514206
Total Pages : 459 pages
Book Rating : 4.2/5 (625 download)

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Book Synopsis Dynamical Systems in Neuroscience by : Eugene M. Izhikevich

Download or read book Dynamical Systems in Neuroscience written by Eugene M. Izhikevich and published by MIT Press. This book was released on 2010-01-22 with total page 459 pages. Available in PDF, EPUB and Kindle. Book excerpt: Explains the relationship of electrophysiology, nonlinear dynamics, and the computational properties of neurons, with each concept presented in terms of both neuroscience and mathematics and illustrated using geometrical intuition. In order to model neuronal behavior or to interpret the results of modeling studies, neuroscientists must call upon methods of nonlinear dynamics. This book offers an introduction to nonlinear dynamical systems theory for researchers and graduate students in neuroscience. It also provides an overview of neuroscience for mathematicians who want to learn the basic facts of electrophysiology. Dynamical Systems in Neuroscience presents a systematic study of the relationship of electrophysiology, nonlinear dynamics, and computational properties of neurons. It emphasizes that information processing in the brain depends not only on the electrophysiological properties of neurons but also on their dynamical properties. The book introduces dynamical systems, starting with one- and two-dimensional Hodgkin-Huxley-type models and continuing to a description of bursting systems. Each chapter proceeds from the simple to the complex, and provides sample problems at the end. The book explains all necessary mathematical concepts using geometrical intuition; it includes many figures and few equations, making it especially suitable for non-mathematicians. Each concept is presented in terms of both neuroscience and mathematics, providing a link between the two disciplines. Nonlinear dynamical systems theory is at the core of computational neuroscience research, but it is not a standard part of the graduate neuroscience curriculum—or taught by math or physics department in a way that is suitable for students of biology. This book offers neuroscience students and researchers a comprehensive account of concepts and methods increasingly used in computational neuroscience. An additional chapter on synchronization, with more advanced material, can be found at the author's website, www.izhikevich.com.

Fundamentals of Computational Neuroscience

Author : Thomas Trappenberg
Publisher : Oxford University Press
ISBN 13 : 0199568413
Total Pages : 417 pages
Book Rating : 4.1/5 (995 download)

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Book Synopsis Fundamentals of Computational Neuroscience by : Thomas Trappenberg

Download or read book Fundamentals of Computational Neuroscience written by Thomas Trappenberg and published by Oxford University Press. This book was released on 2010 with total page 417 pages. Available in PDF, EPUB and Kindle. Book excerpt: The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. Completely redesigned and revised, it introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain.

An Introductory Course in Computational Neuroscience

Author : Paul Miller
Publisher : MIT Press
ISBN 13 : 0262038250
Total Pages : 405 pages
Book Rating : 4.2/5 (62 download)

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Book Synopsis An Introductory Course in Computational Neuroscience by : Paul Miller

Download or read book An Introductory Course in Computational Neuroscience written by Paul Miller and published by MIT Press. This book was released on 2018-10-02 with total page 405 pages. Available in PDF, EPUB and Kindle. Book excerpt: A textbook for students with limited background in mathematics and computer coding, emphasizing computer tutorials that guide readers in producing models of neural behavior. This introductory text teaches students to understand, simulate, and analyze the complex behaviors of individual neurons and brain circuits. It is built around computer tutorials that guide students in producing models of neural behavior, with the associated Matlab code freely available online. From these models students learn how individual neurons function and how, when connected, neurons cooperate in a circuit. The book demonstrates through simulated models how oscillations, multistability, post-stimulus rebounds, and chaos can arise within either single neurons or circuits, and it explores their roles in the brain. The book first presents essential background in neuroscience, physics, mathematics, and Matlab, with explanations illustrated by many example problems. Subsequent chapters cover the neuron and spike production; single spike trains and the underlying cognitive processes; conductance-based models; the simulation of synaptic connections; firing-rate models of large-scale circuit operation; dynamical systems and their components; synaptic plasticity; and techniques for analysis of neuron population datasets, including principal components analysis, hidden Markov modeling, and Bayesian decoding. Accessible to undergraduates in life sciences with limited background in mathematics and computer coding, the book can be used in a “flipped” or “inverted” teaching approach, with class time devoted to hands-on work on the computer tutorials. It can also be a resource for graduate students in the life sciences who wish to gain computing skills and a deeper knowledge of neural function and neural circuits.

Principles of Computational Modelling in Neuroscience

Author : David Sterratt
Publisher : Cambridge University Press
ISBN 13 : 1108483143
Total Pages : 553 pages
Book Rating : 4.1/5 (84 download)

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Book Synopsis Principles of Computational Modelling in Neuroscience by : David Sterratt

Download or read book Principles of Computational Modelling in Neuroscience written by David Sterratt and published by Cambridge University Press. This book was released on 2023-10-05 with total page 553 pages. Available in PDF, EPUB and Kindle. Book excerpt: Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.

Encyclopedia of Computational Neuroscience

Author : Dieter Jäger
Publisher : Springer
ISBN 13 : 9781071610046
Total Pages : 3663 pages
Book Rating : 4.6/5 (1 download)

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Book Synopsis Encyclopedia of Computational Neuroscience by : Dieter Jäger

Download or read book Encyclopedia of Computational Neuroscience written by Dieter Jäger and published by Springer. This book was released on 2022-04-26 with total page 3663 pages. Available in PDF, EPUB and Kindle. Book excerpt: The annual Computational Neuroscience Meeting (CNS) began in 1990 as a small workshop called Analysis and Modeling of Neural Systems. The goal of the workshop was to explore the boundary between neuroscience and computation. Riding on the success of several seminal papers, physicists had made "Neural Networks" fashionable, and soon the quantitative methods used in these abstract model networks started permeating the methods and ideas of experimental neuroscientists. Although experimental neurophysiological approaches provided many advances, it became increasingly evident that mathematical and computational techniques would be required to achieve a comprehensive and quantitative understanding of neural system function. “Computational Neuroscience” emerged to complement experimental neurophysiology. The Encyclopedia of Computational Neuroscience, published in conjunction with the Organization for Computational Neuroscience, will be an extensive reference work consultable by both researchers and graduate level students. It will be a dynamic, living reference, updatable and containing linkouts and multimedia content whenever relevant.

The Neurobiology of Neural Networks

Author : Daniel Gardner
Publisher : MIT Press
ISBN 13 : 9780262071505
Total Pages : 254 pages
Book Rating : 4.0/5 (715 download)

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Book Synopsis The Neurobiology of Neural Networks by : Daniel Gardner

Download or read book The Neurobiology of Neural Networks written by Daniel Gardner and published by MIT Press. This book was released on 1993 with total page 254 pages. Available in PDF, EPUB and Kindle. Book excerpt: This timely overview and synthesis of recent work in both artificial neural networks and neurobiology seeks to examine neurobiological data from a network perspective and to encourage neuroscientists to participate in constructing the next generation of neural networks.

Computational Models of Brain and Behavior

Author : Ahmed A. Moustafa
Publisher : John Wiley & Sons
ISBN 13 : 1119159067
Total Pages : 586 pages
Book Rating : 4.1/5 (191 download)

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Book Synopsis Computational Models of Brain and Behavior by : Ahmed A. Moustafa

Download or read book Computational Models of Brain and Behavior written by Ahmed A. Moustafa and published by John Wiley & Sons. This book was released on 2017-11-13 with total page 586 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.

Olfaction

Author : Joel L. Davis
Publisher : MIT Press
ISBN 13 : 9780262041249
Total Pages : 348 pages
Book Rating : 4.0/5 (412 download)

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Book Synopsis Olfaction by : Joel L. Davis

Download or read book Olfaction written by Joel L. Davis and published by MIT Press. This book was released on 1991 with total page 348 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational neuroscientists have recently turned to modeling olfactory structures because these are likely to have the same functional properties as currently popular network designs for perception and memory. This book provides a useful survey of current work on olfactory system circuitry, including connections of this system to brain structures involved in cognition and memory, and describes the computational models of olfactory processing that have been developed to date. Contributions cover empirical investigations of the neurobiology of the olfactory systems (anatomy, physiology, synaptic plasticity, behavioral physiology) as well as the application of computer models to understanding these systems. Fundamental issues in olfactory processing by the nervous systems such as experimental strategies in the study of olfaction, stages of odor processing, and critical questions in sensory coding are considered across empirical/applied boundaries and throughout the contributions. ContributorsI. Fundamental Anatomy, Physiology, and Plasticity of the Olfactory System, Gordon M. Shepherd. John S. Kauer, S. R. Neff, Kathryn A. Hamilton, and Angel R. Cinelli. Kevin L. Ketchum, Lewis B. Haberly. Joseph L. Price, S. Thomas Carmichael, Ken M. Carnes, Marie Christine Clugnet, Masaru Kuroda, and James P. Ray. Michael Leon, Donald A. Wilson, and Kathleen M. Guthrie. Gary Lynch and Richard Granger. Howard Eichenbaum, Tim Otto, Cynthia Wible, and Jean Piper. - II. Developments in Computational Models of the Olfactory System, DeLiang Wang, Joachim Buhmann, and Christoph von der Marlsburg. Walter Freeman. Richard Granger, Ursula Staubi, José Ambrose-Ingersoll, and Gary Lynch. James M. Bower. Dan Hammerstrom and Eric Means.

Computational Explorations in Cognitive Neuroscience

Author : Randall C. O'Reilly
Publisher : MIT Press
ISBN 13 : 9780262650540
Total Pages : 540 pages
Book Rating : 4.6/5 (55 download)

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Book Synopsis Computational Explorations in Cognitive Neuroscience by : Randall C. O'Reilly

Download or read book Computational Explorations in Cognitive Neuroscience written by Randall C. O'Reilly and published by MIT Press. This book was released on 2000-08-28 with total page 540 pages. Available in PDF, EPUB and Kindle. Book excerpt: This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the computational cognitive neuroscience. The goal of computational cognitive neuroscience is to understand how the brain embodies the mind by using biologically based computational models comprising networks of neuronlike units. This text, based on a course taught by Randall O'Reilly and Yuko Munakata over the past several years, provides an in-depth introduction to the main ideas in the field. The neural units in the simulations use equations based directly on the ion channels that govern the behavior of real neurons, and the neural networks incorporate anatomical and physiological properties of the neocortex. Thus the text provides the student with knowledge of the basic biology of the brain as well as the computational skills needed to simulate large-scale cognitive phenomena. The text consists of two parts. The first part covers basic neural computation mechanisms: individual neurons, neural networks, and learning mechanisms. The second part covers large-scale brain area organization and cognitive phenomena: perception and attention, memory, language, and higher-level cognition. The second part is relatively self-contained and can be used separately for mechanistically oriented cognitive neuroscience courses. Integrated throughout the text are more than forty different simulation models, many of them full-scale research-grade models, with friendly interfaces and accompanying exercises. The simulation software (PDP++, available for all major platforms) and simulations can be downloaded free of charge from the Web. Exercise solutions are available, and the text includes full information on the software.

Computational Neuroscience Models of the Basal Ganglia

Author : V. Srinivasa Chakravarthy
Publisher : Springer
ISBN 13 : 9811084947
Total Pages : 296 pages
Book Rating : 4.8/5 (11 download)

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Book Synopsis Computational Neuroscience Models of the Basal Ganglia by : V. Srinivasa Chakravarthy

Download or read book Computational Neuroscience Models of the Basal Ganglia written by V. Srinivasa Chakravarthy and published by Springer. This book was released on 2018-03-21 with total page 296 pages. Available in PDF, EPUB and Kindle. Book excerpt: The book is a compendium of the aforementioned subclass of models of Basal Ganglia, which presents some the key existent theories of Basal Ganglia function. The book presents computational models of basal ganglia-related disorders, including Parkinson’s disease, schizophrenia, and addiction. Importantly, it highlights the applications of understanding the role of the basal ganglia to treat neurological and psychiatric disorders. The purpose of the present book is to amend and expand on James Houk’s book (MIT press; ASIN: B010BF4U9K) by providing a comprehensive overview on computational models of the basal ganglia. This book caters to researchers and academics from the area of computational cognitive neuroscience.

Nonlinear Dynamics in Computational Neuroscience

Author : Fernando Corinto
Publisher : Springer
ISBN 13 : 3319710486
Total Pages : 141 pages
Book Rating : 4.3/5 (197 download)

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Book Synopsis Nonlinear Dynamics in Computational Neuroscience by : Fernando Corinto

Download or read book Nonlinear Dynamics in Computational Neuroscience written by Fernando Corinto and published by Springer. This book was released on 2018-06-19 with total page 141 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book provides an essential overview of computational neuroscience. It addresses a broad range of aspects, from physiology to nonlinear dynamical approaches to understanding neural computation, and from the simulation of brain circuits to the development of engineering devices and platforms for neuromorphic computation. Written by leading experts in such diverse fields as neuroscience, physics, psychology, neural engineering, cognitive science and applied mathematics, the book reflects the remarkable advances that have been made in the field of computational neuroscience, an emerging discipline devoted to the study of brain functions in terms of the information-processing properties of the structures forming the nervous system. The contents build on the workshop “Nonlinear Dynamics in Computational Neuroscience: from Physics and Biology to ICT,” which was held in Torino, Italy in September 2015.

Neural Engineering

Author : Chris Eliasmith
Publisher : MIT Press
ISBN 13 : 9780262550604
Total Pages : 384 pages
Book Rating : 4.5/5 (56 download)

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Book Synopsis Neural Engineering by : Chris Eliasmith

Download or read book Neural Engineering written by Chris Eliasmith and published by MIT Press. This book was released on 2003 with total page 384 pages. Available in PDF, EPUB and Kindle. Book excerpt: A synthesis of current approaches to adapting engineering tools to the study of neurobiological systems.

The Computational Brain

Author : Patricia Smith Churchland
Publisher : MIT Press
ISBN 13 : 9780262531207
Total Pages : 564 pages
Book Rating : 4.5/5 (312 download)

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Book Synopsis The Computational Brain by : Patricia Smith Churchland

Download or read book The Computational Brain written by Patricia Smith Churchland and published by MIT Press. This book was released on 1992 with total page 564 pages. Available in PDF, EPUB and Kindle. Book excerpt: "The Computational Brain addresses a broad audience: neuroscientists, computer scientists, cognitive scientists, and philosophers. It is written for both the expert and novice. A basic overview of neuroscience and computational theory is provided, followed by a study of some of the most recent and sophisticated modeling work in the context of relevant neurobiological research. Technical terms are clearly explained in the text, and definitions are provided in an extensive glossary. The appendix contains a précis of neurobiological techniques."--Jacket.

Computational Systems Biology

Author : Andres Kriete
Publisher : Elsevier
ISBN 13 : 9780080459349
Total Pages : 424 pages
Book Rating : 4.4/5 (593 download)

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Book Synopsis Computational Systems Biology by : Andres Kriete

Download or read book Computational Systems Biology written by Andres Kriete and published by Elsevier. This book was released on 2005-11-10 with total page 424 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of gene and metabolic networks, as well as modelling and simulation of multi-cellular systems. Central themes include strategies for predicting biological properties and methods for elucidating structure-function relationships.

Computational Neuroscience for Advancing Artificial Intelligence: Models, Methods and Applications

Author : Alonso, Eduardo
Publisher : IGI Global
ISBN 13 : 1609600231
Total Pages : 396 pages
Book Rating : 4.6/5 (96 download)

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Book Synopsis Computational Neuroscience for Advancing Artificial Intelligence: Models, Methods and Applications by : Alonso, Eduardo

Download or read book Computational Neuroscience for Advancing Artificial Intelligence: Models, Methods and Applications written by Alonso, Eduardo and published by IGI Global. This book was released on 2010-11-30 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book argues that computational models in behavioral neuroscience must be taken with caution, and advocates for the study of mathematical models of existing theories as complementary to neuro-psychological models and computational models"--