Computational Methods For Estimating The Kinetic Parameters Of Biological Systems

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Computational Methods for Estimating the Kinetic Parameters of Biological Systems

Author : Quentin Vanhaelen
Publisher : Humana
ISBN 13 : 9781071617694
Total Pages : 0 pages
Book Rating : 4.6/5 (176 download)

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Book Synopsis Computational Methods for Estimating the Kinetic Parameters of Biological Systems by : Quentin Vanhaelen

Download or read book Computational Methods for Estimating the Kinetic Parameters of Biological Systems written by Quentin Vanhaelen and published by Humana. This book was released on 2022-12-24 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This detailed book provides an overview of various classes of computational techniques, including machine learning techniques, commonly used for evaluating kinetic parameters of biological systems. Focusing on three distinct situations, the volume covers the prediction of the kinetics of enzymatic reactions, the prediction of the kinetics of protein-protein or protein-ligand interactions (binding rates, dissociation rates, binding affinities), and the prediction of relatively large set of kinetic rates of reactions usually found in quantitative models of large biological networks. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of expert implementation advice that leads to successful results. Authoritative and practical, Computational Methods for Estimating the Kinetic Parameters of Biological Systems will be of great interest for researchers working through the challenge of identifying the best type of algorithm and who would like to use or develop a computational method for the estimation of kinetic parameters.

Computational Biology

Author : Ralf Blossey
Publisher : CRC Press
ISBN 13 : 1420010786
Total Pages : 276 pages
Book Rating : 4.4/5 (2 download)

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Book Synopsis Computational Biology by : Ralf Blossey

Download or read book Computational Biology written by Ralf Blossey and published by CRC Press. This book was released on 2006-05-25 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Quantitative methods have a particular knack for improving any field they touch. For biology, computational techniques have led to enormous strides in our understanding of biological systems, but there is still vast territory to cover. Statistical physics especially holds great potential for elucidating the structural-functional relationships in bi

Computational Methods in Systems Biology

Author : Monika Heiner
Publisher : Springer
ISBN 13 : 3540885625
Total Pages : 413 pages
Book Rating : 4.5/5 (48 download)

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Book Synopsis Computational Methods in Systems Biology by : Monika Heiner

Download or read book Computational Methods in Systems Biology written by Monika Heiner and published by Springer. This book was released on 2008-10-05 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 6th International Conference on Computational Methods in Systems Biology, CMSB 2008, held in Rostock, Germany, in September 2008. The 21 revised full papers presented together with the summaries of 5 invited papers were carefully reviewed and selected from more than 60 submissions. The papers cover theoretical or applied contributions that are motivated by a biological question focusing on modeling approaches, including process algebra, simulation approaches, analysis methods, in particular model checking and flux analysis, and case studies.

Network Bioscience, 2nd Edition

Author : Marco Pellegrini
Publisher : Frontiers Media SA
ISBN 13 : 288963650X
Total Pages : 270 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Network Bioscience, 2nd Edition by : Marco Pellegrini

Download or read book Network Bioscience, 2nd Edition written by Marco Pellegrini and published by Frontiers Media SA. This book was released on 2020-03-27 with total page 270 pages. Available in PDF, EPUB and Kindle. Book excerpt: Network science has accelerated a deep and successful trend in research that influences a range of disciplines like mathematics, graph theory, physics, statistics, data science and computer science (just to name a few) and adapts the relevant techniques and insights to address relevant but disparate social, biological, technological questions. We are now in an era of 'big biological data' supported by cost-effective high-throughput genomic, transcriptomic, proteomic, metabolomic data collection techniques that allow one to take snapshots of the cells' molecular profiles in a systematic fashion. Moreover recently, also phenotypic data, data on diseases, symptoms, patients, etc. are being collected at nation-wide level thus giving us another source of highly related (causal) 'big data'. This wealth of data is usually modeled as networks (aka binary relations, graphs or webs) of interactions, (including protein-protein, metabolic, signaling and transcription-regulatory interactions). The network model is a key view point leading to the uncovering of mesoscale phenomena, thus providing an essential bridge between the observable phenotypes and 'omics' underlying mechanisms. Moreover, network analysis is a powerful 'hypothesis generation' tool guiding the scientific cycle of 'data gathering', 'data interpretation, 'hypothesis generation' and 'hypothesis testing'. A major challenge in contemporary research is the synthesis of deep insights coming from network science with the wealth of data (often noisy, contradictory, incomplete and difficult to replicate) so to answer meaningful biological questions, in a quantifiable way using static and dynamic properties of biological networks.

Computational Methods in Systems Biology

Author : Ezio Bartocci
Publisher : Springer
ISBN 13 : 3319451774
Total Pages : 361 pages
Book Rating : 4.3/5 (194 download)

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Book Synopsis Computational Methods in Systems Biology by : Ezio Bartocci

Download or read book Computational Methods in Systems Biology written by Ezio Bartocci and published by Springer. This book was released on 2016-09-03 with total page 361 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 14th International Conference on Computational Methods in Systems Biology, CMSB 2016, held in Cambridge, UK, in September 2016. The 20 full papers, 3 tool papers and 9 posters presented were carefully reviewed and selected from 37 regular paper submissions. The topics include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; and computational approaches for synthetic biology.

Computational Approaches in Drug Discovery, Development and Systems Pharmacology

Author : Rupesh Kumar Gautam
Publisher : Elsevier
ISBN 13 : 0323993737
Total Pages : 364 pages
Book Rating : 4.3/5 (239 download)

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Book Synopsis Computational Approaches in Drug Discovery, Development and Systems Pharmacology by : Rupesh Kumar Gautam

Download or read book Computational Approaches in Drug Discovery, Development and Systems Pharmacology written by Rupesh Kumar Gautam and published by Elsevier. This book was released on 2023-02-15 with total page 364 pages. Available in PDF, EPUB and Kindle. Book excerpt: Computational Approaches in Drug Discovery, Development and Systems Pharmacology provides detailed information on the use of computers in advancing pharmacology. Drug discovery and development is an expensive and time-consuming practice, and computer-assisted drug design (CADD) approaches are increasing in popularity in the pharmaceutical industry to accelerate the process. With the help of CADD, scientists can focus on the most capable compounds so that they can minimize the synthetic and biological testing pains. This book examines success stories of CADD in drug discovery, drug development and role of CADD in system pharmacology, additionally including a focus on the role of artificial intelligence (AI) and deep machine learning in pharmacology. Computational Approaches in Drug Discovery, Development and Systems Pharmacology will be useful to researchers and academics working in the area of CADD, pharmacology and Bioinformatics. - Explains computer use in pharmacology using real-life case studies - Provides information about biological activities using computer technology, thus allowing for the possible reduction of the number of animals used for research - Describes the role of AI in pharmacology and applications of CADD in various diseases

Computational Methods in Systems Biology

Author : Ion Petre
Publisher : Springer Nature
ISBN 13 : 3031150341
Total Pages : 324 pages
Book Rating : 4.0/5 (311 download)

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Book Synopsis Computational Methods in Systems Biology by : Ion Petre

Download or read book Computational Methods in Systems Biology written by Ion Petre and published by Springer Nature. This book was released on 2022-08-18 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 20th International Conference on Computational Methods in Systems Biology, CMSB 2022, held in Bucharest, Romania, in September 2022. The 13 full papers and 4 tool papers were carefully reviewed and selected from 43 submissions. CMSB focuses on modeling, simulation, analysis, design and control of biological systems. The papers are arranged thematically as follows: Chemical reaction networks; Boolean networks; continuous and hybrid models; machine learning; software.

Computational Methods in Systems Biology

Author : Luca Bortolussi
Publisher : Springer Nature
ISBN 13 : 3030313042
Total Pages : 396 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Computational Methods in Systems Biology by : Luca Bortolussi

Download or read book Computational Methods in Systems Biology written by Luca Bortolussi and published by Springer Nature. This book was released on 2019-09-16 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the refereed proceedings of the 17th International Conference on Computational Methods in Systems Biology, CMSB 2019, held in Trieste, Italy, in September 2019. The 14 full papers, 7 tool papers and 11 posters were carefully reviewed and selected from 53 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology.

Computational Methods For Understanding Bacterial And Archaeal Genomes

Author : Ying Xu
Publisher : World Scientific
ISBN 13 : 1908979011
Total Pages : 494 pages
Book Rating : 4.9/5 (89 download)

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Book Synopsis Computational Methods For Understanding Bacterial And Archaeal Genomes by : Ying Xu

Download or read book Computational Methods For Understanding Bacterial And Archaeal Genomes written by Ying Xu and published by World Scientific. This book was released on 2008-08-06 with total page 494 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses./a

Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances

Author : Lecca, Paola
Publisher : IGI Global
ISBN 13 : 1613504365
Total Pages : 335 pages
Book Rating : 4.6/5 (135 download)

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Book Synopsis Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances by : Lecca, Paola

Download or read book Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances written by Lecca, Paola and published by IGI Global. This book was released on 2011-12-31 with total page 335 pages. Available in PDF, EPUB and Kindle. Book excerpt: The convergence of biology and computer science was initially motivated by the need to organize and process a growing number of biological observations resulting from rapid advances in experimental techniques. Today, however, close collaboration between biologists, biochemists, medical researchers, and computer scientists has also generated remarkable benefits for the field of computer science. Systemic Approaches in Bioinformatics and Computational Systems Biology: Recent Advances presents new techniques that have resulted from the application of computer science methods to the organization and interpretation of biological data. The book covers three subject areas: bioinformatics, computational biology, and computational systems biology. It focuses on recent, systemic approaches in computer science and mathematics that have been used to model, simulate, and more generally, experiment with biological phenomena at any scale.

Bioinformatics and Drug Discovery

Author : Richard S. Larson
Publisher :
ISBN 13 : 9781617799655
Total Pages : 374 pages
Book Rating : 4.7/5 (996 download)

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Book Synopsis Bioinformatics and Drug Discovery by : Richard S. Larson

Download or read book Bioinformatics and Drug Discovery written by Richard S. Larson and published by . This book was released on 2012 with total page 374 pages. Available in PDF, EPUB and Kindle. Book excerpt: Recent advances in drug discovery have been rapid. The second edition of Bioinformatics and Drug Discovery has been completely updated to include topics that range from new technologies in target identification, genomic analysis, cheminformatics, protein analysis, and network or pathway analysis. Each chapter provides an extended introduction that describes the theory and application of the technology. In the second part of each chapter, detailed procedures related to the use of these technologies and software have been incorporated. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Thorough and intuitive, Bioinformatics and Drug Discovery, Second Edition seeks to aid scientists in the further study of the rapidly expanding field of drug discovery.

Bioremediation

Author : Stephen P. Cummings
Publisher : Humana
ISBN 13 :
Total Pages : 304 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis Bioremediation by : Stephen P. Cummings

Download or read book Bioremediation written by Stephen P. Cummings and published by Humana. This book was released on 2010 with total page 304 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book explores imaginative and ambitious multidisciplinary techniques to remove pollutants from a variety of environments. It addresses broader issues surrounding bioremediation and includes detailed protocols of various effective techniques.

Computational Intelligence Methods for Bioinformatics and Biostatistics

Author : Maria Raposo
Publisher : Springer Nature
ISBN 13 : 3030345858
Total Pages : 334 pages
Book Rating : 4.0/5 (33 download)

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Book Synopsis Computational Intelligence Methods for Bioinformatics and Biostatistics by : Maria Raposo

Download or read book Computational Intelligence Methods for Bioinformatics and Biostatistics written by Maria Raposo and published by Springer Nature. This book was released on 2020-01-22 with total page 334 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book constitutes the thoroughly refereed post-conference proceedings of the 15th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics., CIBB 2018, held in Caparica, Portugal, in September 2018. The 32 revised full papers were carefully reviewed and selected from 51 submissions. The papers present current trends at the edge of computer and life sciences, the application of computational intelligence to a system and synthetic biology and the consequent impact on innovative medicine were presented. Theoretical and experimental biologists also presented novel challenges and fostered multidisciplinary collaboration aiming to blend theory and practice, where the founding theories of the techniques used for modelling and analyzing biological systems are investigated and used for practical applications and the supporting technologies.

Encyclopedia of Cardiovascular Research and Medicine

Author :
Publisher : Elsevier
ISBN 13 : 012805154X
Total Pages : 2854 pages
Book Rating : 4.1/5 (28 download)

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Book Synopsis Encyclopedia of Cardiovascular Research and Medicine by :

Download or read book Encyclopedia of Cardiovascular Research and Medicine written by and published by Elsevier. This book was released on 2017-11-27 with total page 2854 pages. Available in PDF, EPUB and Kindle. Book excerpt: Encyclopedia of Cardiovascular Research and Medicine, Four Volume Set offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.

Stem Cells and Aging

Author : Kursad Turksen
Publisher :
ISBN 13 : 9781627033176
Total Pages : 179 pages
Book Rating : 4.0/5 (331 download)

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Book Synopsis Stem Cells and Aging by : Kursad Turksen

Download or read book Stem Cells and Aging written by Kursad Turksen and published by . This book was released on 2013 with total page 179 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over time, it has become clear that changes in stem cells do occur during aging, not only in their number but also in their relationship to their microenvironment and their functionality as reflected in changes to their metabolome. Stem Cells and Aging: Methods and Protocols brings together chapters from expert contributors with protocols critical for exploring the biology of stem cell aging, all of which is key for understanding these age-related stem cell changes at a basic biology level and at the level of their impacts for regenerative medicine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and easy to use, Stem Cells and Aging: Methods and Protocols serves as an ideal reference to guide investigators toward further valuable answers to the problems of our aging population -- P. 4 of cover.

Computational Methods for Molecular Imaging

Author : Fei Gao
Publisher : Springer
ISBN 13 : 3319184318
Total Pages : 203 pages
Book Rating : 4.3/5 (191 download)

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Book Synopsis Computational Methods for Molecular Imaging by : Fei Gao

Download or read book Computational Methods for Molecular Imaging written by Fei Gao and published by Springer. This book was released on 2015-06-11 with total page 203 pages. Available in PDF, EPUB and Kindle. Book excerpt: This volume contains original submissions on the development and application of molecular imaging computing. The editors invited authors to submit high-quality contributions on a wide range of topics including, but not limited to: • Image Synthesis & Reconstruction of Emission Tomography (PET, SPECT) and other Molecular Imaging Modalities • Molecular Imaging Enhancement • Data Analysis of Clinical & Pre-clinical Molecular Imaging • Multi-Modal Image Processing (PET/CT, PET/MR, SPECT/CT, etc.) • Machine Learning and Data Mining in Molecular Imaging. Molecular imaging is an evolving clinical and research discipline enabling the visualization, characterization and quantification of biological processes taking place at the cellular and subcellular levels within intact living subjects. Computational methods play an important role in the development of molecular imaging, from image synthesis to data analysis and from clinical diagnosis to therapy individualization. This work will bring readers from academia and industry up to date on the most recent developments in this field.

Breakthrough Discoveries in Information Technology Research: Advancing Trends

Author : Khosrow-Pour, D.B.A., Mehdi
Publisher : IGI Global
ISBN 13 : 1605669679
Total Pages : 288 pages
Book Rating : 4.6/5 (56 download)

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Book Synopsis Breakthrough Discoveries in Information Technology Research: Advancing Trends by : Khosrow-Pour, D.B.A., Mehdi

Download or read book Breakthrough Discoveries in Information Technology Research: Advancing Trends written by Khosrow-Pour, D.B.A., Mehdi and published by IGI Global. This book was released on 2009-11-30 with total page 288 pages. Available in PDF, EPUB and Kindle. Book excerpt: "This book informs researchers and practitioners of novel and emerging research in information science and technology, allowing for the discussion and dissemination of critical concepts that will promote further study and innovation"--Provided by publisher.