Complex Systems Science In Biomedicine

Download Complex Systems Science In Biomedicine full books in PDF, epub, and Kindle. Read online Complex Systems Science In Biomedicine ebook anywhere anytime directly on your device. Fast Download speed and no annoying ads. We cannot guarantee that every ebooks is available!

Complex Systems Science in Biomedicine

Author : Thomas Deisboeck
Publisher : Springer Science & Business Media
ISBN 13 : 0387335323
Total Pages : 857 pages
Book Rating : 4.3/5 (873 download)

DOWNLOAD NOW!

Book Synopsis Complex Systems Science in Biomedicine by : Thomas Deisboeck

Download or read book Complex Systems Science in Biomedicine written by Thomas Deisboeck and published by Springer Science & Business Media. This book was released on 2007-06-13 with total page 857 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Complex Systems Science in Biomedicine

Author : Thomas Deisboeck
Publisher : Springer
ISBN 13 : 9780387510767
Total Pages : 864 pages
Book Rating : 4.5/5 (17 download)

DOWNLOAD NOW!

Book Synopsis Complex Systems Science in Biomedicine by : Thomas Deisboeck

Download or read book Complex Systems Science in Biomedicine written by Thomas Deisboeck and published by Springer. This book was released on 2010-11-16 with total page 864 pages. Available in PDF, EPUB and Kindle. Book excerpt: Complex Systems Science in Biomedicine Thomas S. Deisboeck and J. Yasha Kresh Complex Systems Science in Biomedicine covers the emerging field of systems science involving the application of physics, mathematics, engineering and computational methods and techniques to the study of biomedicine including nonlinear dynamics at the molecular, cellular, multi-cellular tissue, and organismic level. With all chapters helmed by leading scientists in the field, Complex Systems Science in Biomedicine's goal is to offer its audience a timely compendium of the ongoing research directed to the understanding of biological processes as whole systems instead of as isolated component parts. In Parts I & II, Complex Systems Science in Biomedicine provides a general systems thinking perspective and presents some of the fundamental theoretical underpinnings of this rapidly emerging field. Part III then follows with a multi-scaled approach, spanning from the molecular to macroscopic level, exemplified by studying such diverse areas as molecular networks and developmental processes, the immune and nervous systems, the heart, cancer and multi-organ failure. The volume concludes with Part IV that addresses methods and techniques driven in design and development by this new understanding of biomedical science. Key Topics Include: • Historic Perspectives of General Systems Thinking • Fundamental Methods and Techniques for Studying Complex Dynamical Systems • Applications from Molecular Networks to Disease Processes • Enabling Technologies for Exploration of Systems in the Life Sciences Complex Systems Science in Biomedicine is essential reading for experimental, theoretical, and interdisciplinary scientists working in the biomedical research field interested in a comprehensive overview of this rapidly emerging field. About the Editors: Thomas S. Deisboeck is currently Assistant Professor of Radiology at Massachusetts General Hospital and Harvard Medical School in Boston. An expert in interdisciplinary cancer modeling, Dr. Deisboeck is Director of the Complex Biosystems Modeling Laboratory which is part of the Harvard-MIT Martinos Center for Biomedical Imaging. J. Yasha Kresh is currently Professor of Cardiothoracic Surgery and Research Director, Professor of Medicine and Director of Cardiovascular Biophysics at the Drexel University College of Medicine. An expert in dynamical systems, he holds appointments in the School of Biomedical Engineering and Health Systems, Dept. of Mechanical Engineering and Molecular Pathobiology Program. Prof. Kresh is Fellow of the American College of Cardiology, American Heart Association, Biomedical Engineering Society, American Institute for Medical and Biological Engineering.

Encyclopedia of Complexity and Systems Science

Author :
Publisher : Springer
ISBN 13 : 9780387758886
Total Pages : 10398 pages
Book Rating : 4.7/5 (588 download)

DOWNLOAD NOW!

Book Synopsis Encyclopedia of Complexity and Systems Science by :

Download or read book Encyclopedia of Complexity and Systems Science written by and published by Springer. This book was released on 2009-06-26 with total page 10398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia provides an authoritative single source for understanding and applying the concepts of complexity theory together with the tools and measures for analyzing complex systems in all fields of science and engineering. It links fundamental concepts of mathematics and computational sciences to applications in the physical sciences, engineering, biomedicine, economics and the social sciences.

Systems Biomedicine

Author : Edison T. Liu
Publisher : Academic Press
ISBN 13 : 9780080919836
Total Pages : 448 pages
Book Rating : 4.9/5 (198 download)

DOWNLOAD NOW!

Book Synopsis Systems Biomedicine by : Edison T. Liu

Download or read book Systems Biomedicine written by Edison T. Liu and published by Academic Press. This book was released on 2009-09-17 with total page 448 pages. Available in PDF, EPUB and Kindle. Book excerpt: Systems biology is a critical emerging field that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modeling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. Organized to reflect the important distinguishing characteristics of systems strategies in experimental biology and medicine Provides precise and comprehensive measurement tools for constructing a model of the system and tools for defining complexity as an experimental dependent variable Includes a thorough discussion of the applications of quantitative principles to biomedical problems

Introduction to Complexity and Complex Systems

Author : Robert B. Northrop
Publisher : CRC Press
ISBN 13 : 1439894981
Total Pages : 551 pages
Book Rating : 4.4/5 (398 download)

DOWNLOAD NOW!

Book Synopsis Introduction to Complexity and Complex Systems by : Robert B. Northrop

Download or read book Introduction to Complexity and Complex Systems written by Robert B. Northrop and published by CRC Press. This book was released on 2010-12-10 with total page 551 pages. Available in PDF, EPUB and Kindle. Book excerpt: The boundaries between simple and complicated, and complicated and complex system designations are fuzzy and debatable, even using quantitative measures of complexity. However, if you are a biomedical engineer, a biologist, physiologist, economist, politician, stock market speculator, or politician, you have encountered complex systems. Furthermore, your success depends on your ability to successfully interact with and manage a variety of complex systems. In order not to be blindsided by unexpected results, we need a systematic, comprehensive way of analyzing, modeling, and simulating complex systems to predict non-anticipated outcomes. In its engaging first chapters, the book introduces complex systems, Campbell's Law, and the Law of Unintended Consequences, and mathematics necessary for conversations in complex systems. Subsequent chapters illustrate concepts via commonly studied biological mechanisms. The final chapters focus on higher-level complexity problems, and introduce complexity in economic systems. Designed as a reference for biologists and biological engineers, Introduction to Complexity and Complex Systems lends itself to use in a classroom course to introduce advanced students studying biomedical engineering, biophysics, or physiology to complex systems. Engaging and illustrative, this book aids scientists and decision makers in managing biological complexity and complex systems.

A Systems Approach to Biomedicine

Author : William B. Blesser
Publisher :
ISBN 13 :
Total Pages : 652 pages
Book Rating : 4.3/5 (91 download)

DOWNLOAD NOW!

Book Synopsis A Systems Approach to Biomedicine by : William B. Blesser

Download or read book A Systems Approach to Biomedicine written by William B. Blesser and published by . This book was released on 1969 with total page 652 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Complex Systems in Medicine

Author : David C. Aron
Publisher : Springer Nature
ISBN 13 : 3030245934
Total Pages : 255 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Complex Systems in Medicine by : David C. Aron

Download or read book Complex Systems in Medicine written by David C. Aron and published by Springer Nature. This book was released on 2019-08-30 with total page 255 pages. Available in PDF, EPUB and Kindle. Book excerpt: This unique title explores complex systems in clinical medicine and the subsequent implementation of that knowledge into practice. Written conversationally and as a reflection on the journey of learning about complex systems, the book explores how knowledge of these systems can be applied to four key roles in academic medicine: clinical practice, education, research, and administration. Further, this title emphasizes how gaining an understanding of complex systems can greatly help a physician deal with the many challenges found in academic medicine. Unlike other books on complexity in medicine, which tend to focus on only one aspect of the management of patients, Complex Systems in Medicine deals with the multifaceted roles of a physician. The approach in this book is uniquely qualitative rather than mathematical, and is written to make it not only of interest to physicians, trainees, and allied health providers, but also to make it more accessible to a non-medical audience. The inclusion of personal anecdotes by the author provides concrete examples of the application of knowledge of complex systems in academic medicine. A first-of-its-kind contribution to the literature, Complex Systems in Medicine: A Hedgehog’s Tale of Complexity in Clinical Practice, Research, Education, and Management is not only a novel reference for medical professionals, it is an accessible tool for the non-medical audience hoping to learn more about complex systems and their direct relevance to medicine, a field that deals with the infinite variety of humans and their ills. It illustrates the consequences of the interactive elements of patient care that make medicine both a science and an art.

Handbook of Systems and Complexity in Health

Author : Joachim P Sturmberg
Publisher : Springer Science & Business Media
ISBN 13 : 1461449987
Total Pages : 941 pages
Book Rating : 4.4/5 (614 download)

DOWNLOAD NOW!

Book Synopsis Handbook of Systems and Complexity in Health by : Joachim P Sturmberg

Download or read book Handbook of Systems and Complexity in Health written by Joachim P Sturmberg and published by Springer Science & Business Media. This book was released on 2013-01-09 with total page 941 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an introduction to health care as a complex adaptive system, a system that feeds back on itself. The first section introduces systems and complexity theory from a science, historical, epistemological, and technical perspective, describing the principles and mathematics. Subsequent sections build on the health applications of systems science theory, from human physiology to medical decision making, population health and health services research. The aim of the book is to introduce and expand on important population health issues from a systems and complexity perspective, highlight current research developments and their implications for health care delivery, consider their ethical implications, and to suggest directions for and potential pitfalls in the future.

Proceedings of the European Conference on Complex Systems 2012

Author : Thomas Gilbert
Publisher : Springer Science & Business Media
ISBN 13 : 331900395X
Total Pages : 1096 pages
Book Rating : 4.3/5 (19 download)

DOWNLOAD NOW!

Book Synopsis Proceedings of the European Conference on Complex Systems 2012 by : Thomas Gilbert

Download or read book Proceedings of the European Conference on Complex Systems 2012 written by Thomas Gilbert and published by Springer Science & Business Media. This book was released on 2013-08-15 with total page 1096 pages. Available in PDF, EPUB and Kindle. Book excerpt: The European Conference on Complex Systems, held under the patronage of the Complex Systems Society, is an annual event that has become the leading European conference devoted to complexity science. ECCS'12, its ninth edition, took place in Brussels, during the first week of September 2012. It gathered about 650 scholars representing a wide range of topics relating to complex systems research, with emphasis on interdisciplinary approaches. More specifically, the following tracks were covered: 1. Foundations of Complex Systems 2. Complexity, Information and Computation 3. Prediction, Policy and Planning, Environment 4. Biological Complexity 5. Interacting Populations, Collective Behavior 6. Social Systems, Economics and Finance This book contains a selection of the contributions presented at the conference and its satellite meetings. Its contents reflect the extent, diversity and richness of research areas in the field, both fundamental and applied.

Emergent Behavior in Complex Systems Engineering

Author : Saurabh Mittal
Publisher : John Wiley & Sons
ISBN 13 : 1119378869
Total Pages : 416 pages
Book Rating : 4.1/5 (193 download)

DOWNLOAD NOW!

Book Synopsis Emergent Behavior in Complex Systems Engineering by : Saurabh Mittal

Download or read book Emergent Behavior in Complex Systems Engineering written by Saurabh Mittal and published by John Wiley & Sons. This book was released on 2018-04-17 with total page 416 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive text that reviews the methods and technologies that explore emergent behavior in complex systems engineering in multidisciplinary fields In Emergent Behavior in Complex Systems Engineering, the authors present the theoretical considerations and the tools required to enable the study of emergent behaviors in manmade systems. Information Technology is key to today’s modern world. Scientific theories introduced in the last five decades can now be realized with the latest computational infrastructure. Modeling and simulation, along with Big Data technologies are at the forefront of such exploration and investigation. The text offers a number of simulation-based methods, technologies, and approaches that are designed to encourage the reader to incorporate simulation technologies to further their understanding of emergent behavior in complex systems. The authors present a resource for those designing, developing, managing, operating, and maintaining systems, including system of systems. The guide is designed to help better detect, analyse, understand, and manage the emergent behaviour inherent in complex systems engineering in order to reap the benefits of innovations and avoid the dangers of unforeseen consequences. This vital resource: Presents coverage of a wide range of simulation technologies Explores the subject of emergence through the lens of Modeling and Simulation (M&S) Offers contributions from authors at the forefront of various related disciplines such as philosophy, science, engineering, sociology, and economics Contains information on the next generation of complex systems engineering Written for researchers, lecturers, and students, Emergent Behavior in Complex Systems Engineering provides an overview of the current discussions on complexity and emergence, and shows how systems engineering methods in general and simulation methods in particular can help in gaining new insights in complex systems engineering.

Modeling and Managing Interdependent Complex Systems of Systems

Author : Yacov Y. Haimes
Publisher : John Wiley & Sons
ISBN 13 : 1119173698
Total Pages : 928 pages
Book Rating : 4.1/5 (191 download)

DOWNLOAD NOW!

Book Synopsis Modeling and Managing Interdependent Complex Systems of Systems by : Yacov Y. Haimes

Download or read book Modeling and Managing Interdependent Complex Systems of Systems written by Yacov Y. Haimes and published by John Wiley & Sons. This book was released on 2018-09-04 with total page 928 pages. Available in PDF, EPUB and Kindle. Book excerpt: A comprehensive guide to the theory, methodology, and development for modeling systems of systems Modeling and Managing Interdependent Complex Systems of Systems examines the complexity of, and the risk to, emergent interconnected and interdependent complex systems of systems in the natural and the constructed environment, and in its critical infrastructures. For systems modelers, this book focuses on what constitutes complexity and how to understand, model and manage it.Previous modeling methods for complex systems of systems were aimed at developing theory and methodologies for uncoupling the interdependencies and interconnections that characterize them. In this book, the author extends the above by utilizing public- and private- sector case studies; identifies, explores, and exploits the core of interdependencies; and seeks to understand their essence via the states of the system, and their dominant contributions to the complexity of systems of systems. The book proposes a reevaluation of fundamental and practical systems engineering and risk analysis concepts on complex systems of systems developed over the past 40 years. This important resource: Updates and streamlines systems engineering theory, methodology, and practice as applied to complex systems of systems Introduces modeling methodology inspired by philosophical and conceptual thinking from the arts and sciences Models the complexity of emergent interdependent and interconnected complex systems of systems by analyzing their shared states, decisions, resources, and decisionmakers Written for systems engineers, industrial engineers, managers, planners, academics and other professionals in engineering systems and the environment,this text is the resource for understanding the fundamental principles of modeling and managing complex systems of systems, and the risk thereto.

Encyclopedia of Complexity and Systems Science

Author :
Publisher : Springer
ISBN 13 : 9780387695723
Total Pages : 10398 pages
Book Rating : 4.6/5 (957 download)

DOWNLOAD NOW!

Book Synopsis Encyclopedia of Complexity and Systems Science by :

Download or read book Encyclopedia of Complexity and Systems Science written by and published by Springer. This book was released on 2009-07-24 with total page 10398 pages. Available in PDF, EPUB and Kindle. Book excerpt: This encyclopedia provides an authoritative single source for understanding and applying the concepts of complexity theory together with the tools and measures for analyzing complex systems in all fields of science and engineering. It links fundamental concepts of mathematics and computational sciences to applications in the physical sciences, engineering, biomedicine, economics and the social sciences.

The Role of Model Integration in Complex Systems Modelling

Author : Manish Patel
Publisher : Springer
ISBN 13 : 3642156037
Total Pages : 168 pages
Book Rating : 4.6/5 (421 download)

DOWNLOAD NOW!

Book Synopsis The Role of Model Integration in Complex Systems Modelling by : Manish Patel

Download or read book The Role of Model Integration in Complex Systems Modelling written by Manish Patel and published by Springer. This book was released on 2010-10-02 with total page 168 pages. Available in PDF, EPUB and Kindle. Book excerpt: Model integration – the process by which different modelling efforts can be brought together to simulate the target system – is a core technology in the field of Systems Biology. In the work presented here model integration was addressed directly taking cancer systems as an example. An in-depth literature review was carried out to survey the model forms and types currently being utilised. This was used to formalise the main challenges that model integration poses, namely that of paradigm (the formalism on which a model is based), focus (the real-world system the model represents) and scale. A two-tier model integration strategy, including a knowledge-driven approach to address model semantics, was developed to tackle these challenges. In the first step a novel description of models at the level of behaviour, rather than the precise mathematical or computational basis of the model, is developed by distilling a set of abstract classes and properties. These can accurately describe model behaviour and hence describe focus in a way that can be integrated with behavioural descriptions of other models. In the second step this behaviour is decomposed into an agent-based system by translating the models into local interaction rules. The book provides a detailed and highly integrated presentation of the method, encompassing both its novel theoretical and practical aspects, which will enable the reader to practically apply it to their model integration needs in academic research and professional settings. The text is self-supporting. It also includes an in-depth current bibliography to relevant research papers and literature. The review of the current state of the art in tumour modelling provides added value.

Complex Adaptive Systems

Author : Ted Carmichael
Publisher : Springer
ISBN 13 : 3030203093
Total Pages : 250 pages
Book Rating : 4.0/5 (32 download)

DOWNLOAD NOW!

Book Synopsis Complex Adaptive Systems by : Ted Carmichael

Download or read book Complex Adaptive Systems written by Ted Carmichael and published by Springer. This book was released on 2019-06-14 with total page 250 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book emerged out of international conferences organized as part of the AAAI Fall Symposia series, and the Swarmfest 2017 conference. It brings together researchers from diverse fields studying these complex systems using CAS and agent-based modeling tools and techniques. In the past, the knowledge gained in each domain has largely remained exclusive to that domain. By bringing together scholars who study these phenomena, the book takes knowledge from one domain to provide insight into others. Most interesting phenomena in natural and social systems include constant transitions and oscillations among their various phases – wars, companies, societies, markets, and humans rarely stay in a stable, predictable state for long. Randomness, power laws, and human behavior ensure that the future is both unknown and challenging. How do events unfold? When do they take hold? Why do some initial events cause an avalanche while others do not? What characterizes these events? What are the thresholds that differentiate a sea change from a non-event? Complex adaptive systems (CAS) have proven to be a powerful tool for exploring these and other related phenomena. The authors characterize a general CAS model as having a large number of self-similar agents that: 1) utilize one or more levels of feedback; 2) exhibit emergent properties and self-organization; and 3) produce non-linear dynamic behavior. Advances in modeling and computing technology have led not only to a deeper understanding of complex systems in many areas, but they have also raised the possibility that similar fundamental principles may be at work across these systems, even though the underlying principles may manifest themselves differently.

Comprehending the Complexity of Countries

Author : Hans Kuijper
Publisher : Springer Nature
ISBN 13 : 9811647097
Total Pages : 413 pages
Book Rating : 4.8/5 (116 download)

DOWNLOAD NOW!

Book Synopsis Comprehending the Complexity of Countries by : Hans Kuijper

Download or read book Comprehending the Complexity of Countries written by Hans Kuijper and published by Springer Nature. This book was released on 2022-01-18 with total page 413 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book argues for computer-aided collaborative country research based on the science of complex and dynamic systems. It provides an in-depth discussion of systems and computer science, concluding that proper understanding of a country is only possible if a genuinely interdisciplinary and truly international approach is taken; one that is based on complexity science and supported by computer science. Country studies should be carefully designed and collaboratively carried out, and a new generation of country students should pay more attention to the fast growing potential of digitized and electronically connected libraries. In this frenzied age of globalization, foreign policy makers may – to the benefit of a better world – profit from the radically new country studies pleaded for in the book. Its author emphasizes that reductionism and holism are not antagonistic but complementary, arguing that parts are always parts of a whole and a whole has always parts.

Biomedical Science

Author : Ian Lyons
Publisher : John Wiley & Sons
ISBN 13 : 1118294718
Total Pages : 560 pages
Book Rating : 4.1/5 (182 download)

DOWNLOAD NOW!

Book Synopsis Biomedical Science by : Ian Lyons

Download or read book Biomedical Science written by Ian Lyons and published by John Wiley & Sons. This book was released on 2011-11-16 with total page 560 pages. Available in PDF, EPUB and Kindle. Book excerpt: This brand new Lecture Notes title provides the core biomedical science study and revision material that medical students need to know. Matching the common systems-based approach taken by the majority of medical schools, it provides concise, student-led content that is rooted in clinical relevance. The book is filled with learning features such as key definitions and key conditions, and is cross-referenced to develop interdisciplinary awareness. Although designed predominantly for medical students, this new Lecture Notes book is also useful for students of dentistry, pharmacology and nursing. Biomedical Science Lecture Notes provides: A brand new title in the award-winning Lecture Notes series A concise, full colour study and revision guide A 'one-stop-shop' for the biomedical sciences Clinical relevance and cross referencing to develop interdisciplinary skills Learning features such as key definitions to aid understanding

Agent-Based Modelling of Socio-Technical Systems

Author : Koen H. van Dam
Publisher : Springer Science & Business Media
ISBN 13 : 9400749333
Total Pages : 268 pages
Book Rating : 4.4/5 (7 download)

DOWNLOAD NOW!

Book Synopsis Agent-Based Modelling of Socio-Technical Systems by : Koen H. van Dam

Download or read book Agent-Based Modelling of Socio-Technical Systems written by Koen H. van Dam and published by Springer Science & Business Media. This book was released on 2012-10-08 with total page 268 pages. Available in PDF, EPUB and Kindle. Book excerpt: Decision makers in large scale interconnected network systems require simulation models for decision support. The behaviour of these systems is determined by many actors, situated in a dynamic, multi-actor, multi-objective and multi-level environment. How can such systems be modelled and how can the socio-technical complexity be captured? Agent-based modelling is a proven approach to handle this challenge. This book provides a practical introduction to agent-based modelling of socio-technical systems, based on a methodology that has been developed at TU Delft and which has been deployed in a large number of case studies. The book consists of two parts: the first presents the background, theory and methodology as well as practical guidelines and procedures for building models. In the second part this theory is applied to a number of case studies, where for each model the development steps are presented extensively, preparing the reader for creating own models.