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Bayesian Methods in Pharmaceutical Research

Author : Emmanuel Lesaffre
Publisher : CRC Press
ISBN 13 : 1351718673
Total Pages : 547 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Bayesian Methods in Pharmaceutical Research by : Emmanuel Lesaffre

Download or read book Bayesian Methods in Pharmaceutical Research written by Emmanuel Lesaffre and published by CRC Press. This book was released on 2020-04-15 with total page 547 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the early 2000s, there has been increasing interest within the pharmaceutical industry in the application of Bayesian methods at various stages of the research, development, manufacturing, and health economic evaluation of new health care interventions. In 2010, the first Applied Bayesian Biostatistics conference was held, with the primary objective to stimulate the practical implementation of Bayesian statistics, and to promote the added-value for accelerating the discovery and the delivery of new cures to patients. This book is a synthesis of the conferences and debates, providing an overview of Bayesian methods applied to nearly all stages of research and development, from early discovery to portfolio management. It highlights the value associated with sharing a vision with the regulatory authorities, academia, and pharmaceutical industry, with a view to setting up a common strategy for the appropriate use of Bayesian statistics for the benefit of patients. The book covers: Theory, methods, applications, and computing Bayesian biostatistics for clinical innovative designs Adding value with Real World Evidence Opportunities for rare, orphan diseases, and pediatric development Applied Bayesian biostatistics in manufacturing Decision making and Portfolio management Regulatory perspective and public health policies Statisticians and data scientists involved in the research, development, and approval of new cures will be inspired by the possible applications of Bayesian methods covered in the book. The methods, applications, and computational guidance will enable the reader to apply Bayesian methods in their own pharmaceutical research.

Immunological Mechanisms, Biomarkers and Immunotherapies of Alzheimer's Disease

Author : Yu-Hui Liu
Publisher : Frontiers Media SA
ISBN 13 : 2889713644
Total Pages : 124 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Immunological Mechanisms, Biomarkers and Immunotherapies of Alzheimer's Disease by : Yu-Hui Liu

Download or read book Immunological Mechanisms, Biomarkers and Immunotherapies of Alzheimer's Disease written by Yu-Hui Liu and published by Frontiers Media SA. This book was released on 2021-09-24 with total page 124 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nelson's Directory of Investment Research

Author :
Publisher :
ISBN 13 :
Total Pages : 1336 pages
Book Rating : 4.3/5 ( download)

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Book Synopsis Nelson's Directory of Investment Research by :

Download or read book Nelson's Directory of Investment Research written by and published by . This book was released on 2008 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nelson Information's Directory of Investment Research

Author :
Publisher :
ISBN 13 :
Total Pages : 1336 pages
Book Rating : 4.:/5 ( download)

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Book Synopsis Nelson Information's Directory of Investment Research by :

Download or read book Nelson Information's Directory of Investment Research written by and published by . This book was released on 2008 with total page 1336 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Behavioral and Cognitive Impairments Across the Life Span

Author : Beatrice Arosio
Publisher : Frontiers Media SA
ISBN 13 : 2889743748
Total Pages : 396 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Behavioral and Cognitive Impairments Across the Life Span by : Beatrice Arosio

Download or read book Behavioral and Cognitive Impairments Across the Life Span written by Beatrice Arosio and published by Frontiers Media SA. This book was released on 2022-02-11 with total page 396 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Canadian Almanac and Directory 2017

Author : House Canada Grey
Publisher :
ISBN 13 : 9781619259539
Total Pages : 2550 pages
Book Rating : 4.2/5 (595 download)

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Book Synopsis Canadian Almanac and Directory 2017 by : House Canada Grey

Download or read book Canadian Almanac and Directory 2017 written by House Canada Grey and published by . This book was released on 2016-11 with total page 2550 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Canadian Almanac & Directory is the most complete source of Canadian information available - cultural, professional and financial institutions, legislative, governmental, judicial and educational organizations. Canada's authoritative sourcebook for almost 160 years, the Canadian Almanac & Directory gives you access to almost 100,000 names and addresses of contacts throughout the network of Canadian institutions.

Network Spread Models of Neurodegenerative Diseases

Author : Ashish Raj
Publisher : Frontiers Media SA
ISBN 13 : 2889457680
Total Pages : 116 pages
Book Rating : 4.8/5 (894 download)

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Book Synopsis Network Spread Models of Neurodegenerative Diseases by : Ashish Raj

Download or read book Network Spread Models of Neurodegenerative Diseases written by Ashish Raj and published by Frontiers Media SA. This book was released on 2019-04-18 with total page 116 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is a real pleasure to introduce the excellent papers contributed by leading experts to our Research Topic proposing various network models of dementia spread. The focus is strongly on disease-specific mathematical modeling rather than general graph theory. The emerging field of network neuroscience visualizes the brain as a graph consisting of nodes representing regions and edges as connections between them. This complex network supports efficient communication along neural projections, but also, unfortunately, the transmission and progression of Alzheimer’s and other neurodegenerative disorders. If we could know the brain’s network organization, could we then predict how degenerative processes might develop on this network? As these papers demonstrate, the answer is, increasingly, yes.

Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies

Author : Angelo Facchiano
Publisher : Frontiers Media SA
ISBN 13 : 2889637522
Total Pages : 175 pages
Book Rating : 4.8/5 (896 download)

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Book Synopsis Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies by : Angelo Facchiano

Download or read book Artificial Intelligence Bioinformatics: Development and Application of Tools for Omics and Inter-Omics Studies written by Angelo Facchiano and published by Frontiers Media SA. This book was released on 2020-06-18 with total page 175 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Biomarkers from Multi-tracer and Multi-modal Neuroimaging in Age-related Neurodegenerative Diseases

Author : Ping Wu
Publisher : Frontiers Media SA
ISBN 13 : 2889769569
Total Pages : 329 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Biomarkers from Multi-tracer and Multi-modal Neuroimaging in Age-related Neurodegenerative Diseases by : Ping Wu

Download or read book Biomarkers from Multi-tracer and Multi-modal Neuroimaging in Age-related Neurodegenerative Diseases written by Ping Wu and published by Frontiers Media SA. This book was released on 2022-09-12 with total page 329 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Intervention and Alzheimer’s Disease

Author : C.A. Raji
Publisher : IOS Press
ISBN 13 : 1643685015
Total Pages : 768 pages
Book Rating : 4.6/5 (436 download)

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Book Synopsis Handbook of Intervention and Alzheimer’s Disease by : C.A. Raji

Download or read book Handbook of Intervention and Alzheimer’s Disease written by C.A. Raji and published by IOS Press. This book was released on 2024-02-22 with total page 768 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of managing some of the modifiable risk factors associated with the disease has been present from the outset. Intervening to manage risk factors as a way of tackling AD is not new, but optimizing brain health as a way of minimizing risk and maximizing the potential benefits of revolutionary new treatments for AD is becoming increasingly important. This book, the Handbook of Intervention and Alzheimer’s Disease, presents 47 papers exploring factors which may either inspire or inform future treatment and clinical trials. While novel interventions such as anti-amyloid immunotherapy present great opportunities, they may also increase the risk of brain bleeds and edema, which in turn may lead to adverse clinical outcomes. Such adverse outcomes are demonstrably more likely to occur in persons with poor brain health, so improved management of the risk factors which make up the AD preventome will also minimize the risks associated with such novel therapies. The papers in this volume can therefore be thought of as offering insight into those factors that can optimize brain health or providing key insights into interventions which may achieve such outcomes. Together with its companion volume on prevention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: Improved hypoperfusion (resolving blue colors) on ASL MRI Z-score maps superimposed on structural MRI scans at baseline and one year in a PET amyloid-positive research participant with cognitive complaints undergoing one year of multi-domain personalized brain health interventions (vascular disease management, dietary optimization, sustained physical activity etc.). Permission to use this figure was granted both by the study P.I. Dr. David Merrill, MD, PhD, of the Pacific Neuroscience Institute and the research participant.

Artificial Intelligence for eHealth

Author : Deepak Gupta
Publisher : Frontiers Media SA
ISBN 13 : 2889749762
Total Pages : 91 pages
Book Rating : 4.8/5 (897 download)

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Book Synopsis Artificial Intelligence for eHealth by : Deepak Gupta

Download or read book Artificial Intelligence for eHealth written by Deepak Gupta and published by Frontiers Media SA. This book was released on 2022-04-25 with total page 91 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Nutrition and Diabetes

Author : Emmanuel C. Opara
Publisher : CRC Press
ISBN 13 : 1351780107
Total Pages : 471 pages
Book Rating : 4.3/5 (517 download)

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Book Synopsis Nutrition and Diabetes by : Emmanuel C. Opara

Download or read book Nutrition and Diabetes written by Emmanuel C. Opara and published by CRC Press. This book was released on 2019-01-03 with total page 471 pages. Available in PDF, EPUB and Kindle. Book excerpt: Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches. Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.

Multinational Management

Author : Rien Segers
Publisher : Springer
ISBN 13 : 3319230123
Total Pages : 367 pages
Book Rating : 4.3/5 (192 download)

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Book Synopsis Multinational Management by : Rien Segers

Download or read book Multinational Management written by Rien Segers and published by Springer. This book was released on 2016-01-29 with total page 367 pages. Available in PDF, EPUB and Kindle. Book excerpt: This casebook demonstrates that the future of global business lies in how well the multinational landscape is charted and how the importance of Asian market leaders is deeply embedded in it. It offers international management students and researchers an extensive guide to the business history, strategy development, and foreign market entry modes used by emerging Asian multinationals. The cases focus on well-known companies such as Lenovo, Alibaba, Infosys, Huawei, Panasonic, and Rakuten. These companies, all of which generate huge revenues in their own countries (e.g. in China, India, South Korea, Taiwan, Vietnam), are now becoming increasingly sophisticated and striving to become global brands, while also enjoying the active support of their governments in terms of their international business. Readers will learn about the current multinational landscape in Asia, the management challenges, and the future implications for traditional western companies seeking to retain their market share. Chapters on corporate entrepreneurship, human resource management and intercultural competence, and current branding trends in Asia will provide a cutting-edge update on international business strategy for students and practitioners alike.

Doing Business in Boston

Author : Jeffrey P. Levine
Publisher :
ISBN 13 : 9780964098916
Total Pages : 612 pages
Book Rating : 4.0/5 (989 download)

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Book Synopsis Doing Business in Boston by : Jeffrey P. Levine

Download or read book Doing Business in Boston written by Jeffrey P. Levine and published by . This book was released on 1996-06 with total page 612 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Handbook of Prevention and Alzheimer’s Disease

Author : C.A. Raji
Publisher : IOS Press
ISBN 13 : 1643684930
Total Pages : 674 pages
Book Rating : 4.6/5 (436 download)

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Book Synopsis Handbook of Prevention and Alzheimer’s Disease by : C.A. Raji

Download or read book Handbook of Prevention and Alzheimer’s Disease written by C.A. Raji and published by IOS Press. This book was released on 2024-02-20 with total page 674 pages. Available in PDF, EPUB and Kindle. Book excerpt: It is almost 120 years since Alzheimer’s disease (AD) was first reported, and the concept of modifiable risk factors associated with the disease has been present from the outset. Thus, the idea of preventing AD is not new, with reference to strategies noted as early as the 1990s. This subfield of AD research has matured in recent years, with the number of modifiable risk factors – the AD preventome – rising from the 7 initially identified to the current 12, with an estimated contribution to dementia cases worldwide of about 40%. This book, the Handbook of Prevention and Alzheimer’s Disease, introduces physicians, scientists, and other stakeholders to this subfield of AD research. It investigates the AD preventome, which will continue to expand as the understanding of new factors and related biomarkers is refined. Optimizing this preventome leads to an improvement in overall brain health, an outcome which reduces the risk of developing AD and improves quality of life. The book goes on to examine other domains of prevention, from vascular risk factors to social engagement and from sleep health to spirituality. If the journey to end AD can be likened to a long and arduous challenge, understanding every possible part of the overall toolkit of approaches for disease prevention and intervention is essential. Together with its companion volume on intervention, the book provides a comprehensive overview of strategies for tackling Alzheimer’s disease, and will be of interest to all those working in the field. Cover illustration: White matter tracts showing sex differences in connectivity in men versus women as a function of increasing body mass index. Reprinted with permission from Rahmani F, Wang Q, McKay NS, Keefe S, Hantler N, Hornbeck R, Wang Y, Hassenstab J, Schindler S, Xiong C, Morris JC, Benzinger TLS, Raji CA. Sex-Specific Patterns of Body Mass Index Relationship with White Matter Connectivity. J Alzheimers Dis. 2022;86(4):1831-1848. doi: 10.3233/JAD-215329. PMID: 35180116; PMCID: PMC9108572.

LexisNexis Corporate Affiliations

Author :
Publisher :
ISBN 13 :
Total Pages : 2164 pages
Book Rating : 4.3/5 (91 download)

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Book Synopsis LexisNexis Corporate Affiliations by :

Download or read book LexisNexis Corporate Affiliations written by and published by . This book was released on 2008 with total page 2164 pages. Available in PDF, EPUB and Kindle. Book excerpt:

Masterpieces of Swiss Entrepreneurship

Author : Jean-Pierre Jeannet
Publisher : Springer Nature
ISBN 13 : 3030652874
Total Pages : 579 pages
Book Rating : 4.0/5 (36 download)

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Book Synopsis Masterpieces of Swiss Entrepreneurship by : Jean-Pierre Jeannet

Download or read book Masterpieces of Swiss Entrepreneurship written by Jean-Pierre Jeannet and published by Springer Nature. This book was released on 2021-04-21 with total page 579 pages. Available in PDF, EPUB and Kindle. Book excerpt: This open access book focuses on Switzerland-based medium-sized companies with a longstanding export tradition and a proven dominance in global niche markets. Based upon in-depth documentation and analysis of 36 Swiss companies over their entire history, an expert team of authors presents several parallels in the pathways and success factors which allowed these firms to become dominant and operate from a high-cost location such as Switzerland. The book enhances these insights by providing detailed company profiles documenting the company history, development, and how their relevant global niche positions were reached. Readers will benefit from these profiles as they compile a diverse selection of industries, mainly active within the B2B sector, with mostly mature companies (60 years to older than 100 years since founding) and different types of ownership structures including family firms. ‘Masterpieces of Swiss Entrepreneurship’ brings unique learning opportunities to owners and leaders of SMEs in Switzerland and elsewhere. Findings are based on detailed bottom-up research of 36 companies -- without any preconceived notions. The book is both conceptual and practical. It fosters understanding for different choices in development pathways and management practices. Matti Alahuhta, Chairman DevCo Partners, ex-CEO Kone, Board member of several global listed companies, Helsinki, Finland Start-up entrepreneurs need proven models from industry which demonstrate the various paths to success. “Masterpieces of Swiss Entrepreneurship” provides deep insights highlighting these models and the important trade-offs entrepreneurial teams must consider when choosing the path of high growth or of maximum control, as they are often mutually exclusive. Gina Domanig, Managing Partner, Emerald Technology Ventures, Zurich