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Company Profiles Ngm Biopharmaceuticals Inc
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Download or read book Panel World written by and published by . This book was released on 2006 with total page 528 pages. Available in PDF, EPUB and Kindle. Book excerpt: Includes annual: Directory/buyer's guide.
Book Synopsis SITC’s Guide to Managing Immunotherapy Toxicity by : Marc S. Ernstoff, MD
Download or read book SITC’s Guide to Managing Immunotherapy Toxicity written by Marc S. Ernstoff, MD and published by Springer Publishing Company. This book was released on 2019-03-15 with total page 275 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Society for Immunotherapy of Cancer's handbook,SITC’s Guide to Managing Immunotherapy Toxicity, is a practical reference to managing side effects associated with FDA-approved cancer immunotherapy drugs. Separated into two parts, Part I contains chapter-based overviews of immune checkpoint inhibitors in the clinic, starting with anti-CTLA4 agents, anti-PD1/PD-L1 agents, and approved immunotherapeutic combinations. These chapters cover relevant mechanisms of action, indications, and toxicities seen while combating early, advanced, and metastatic stages in cancer patients. Part II is structured by common and uncommon toxicities that affect major organ sites throughout the body. It begins with a general summary of principles and management options followed by chapters focusing on specific toxicities such as rash and mucosal irritation, muscle and joint toxicity, diarrhea and colitis, pneumonitis, endocrine toxicities, neurological toxicities, cardiac toxicity, renal toxicity, hematologic toxicity, and ocular toxicities. Each chapter provides guidance on how to assess and treat the toxicity and how to support the patient through acute and chronic effects with detailed summary tables for quick reference. Part II concludes with chapters covering management of special patient populations, including patients with autoimmune disease and geriatric patients, treatment and management of fatigue, and a final chapter dedicated to cost effectiveness and the toll of financial toxicity on patients and caregivers. With chapters written by world-recognized leaders in the immuno-oncology field, this text provides thorough coverage of the toxicity and management of adverse effects for immune checkpoint inhibitors. It is an indispensable resource for clinical oncologists, emergency physicians, hospitalists and other medical practitioners in both the hospital and community clinic settings, especially as the use of immune checkpoint inhibitors becomes a fixture in oncology care. Key Features: Outlines strategies for treating high-risk patients facing an acute or chronic side effect to immunotherapy Provides numerous tables that condense and highlight pertinent information for quick reference Describes the various clinical presentations and toxic reactions caused by immunotherapy Purchase includes access to the eBook for use on most mobile devices or computer
Download or read book The Advertising Red Books written by and published by . This book was released on 2007-07 with total page 1238 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Innovations for Next-Generation Antibody-Drug Conjugates by : Marc Damelin
Download or read book Innovations for Next-Generation Antibody-Drug Conjugates written by Marc Damelin and published by Springer. This book was released on 2018-05-29 with total page 358 pages. Available in PDF, EPUB and Kindle. Book excerpt: Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
Book Synopsis The Night Before Baseball at the Park by the Bay by : David Schnell
Download or read book The Night Before Baseball at the Park by the Bay written by David Schnell and published by San Francisco Baseball Associates. This book was released on 2014-09-01 with total page 32 pages. Available in PDF, EPUB and Kindle. Book excerpt: A boy dreams of pitching a winning game with his beloved San Francisco Giants baseball team.
Book Synopsis Standard & Poor's Stock Reports by :
Download or read book Standard & Poor's Stock Reports written by and published by . This book was released on 2008 with total page 1340 pages. Available in PDF, EPUB and Kindle. Book excerpt:
Book Synopsis Engine of Impact by : William F. Meehan III
Download or read book Engine of Impact written by William F. Meehan III and published by Stanford University Press. This book was released on 2017-11-14 with total page 307 pages. Available in PDF, EPUB and Kindle. Book excerpt: We are entering a new era—an era of impact. The largest intergenerational transfer of wealth in history will soon be under way, bringing with it the potential for huge increases in philanthropic funding. Engine of Impact shows how nonprofits can apply the principles of strategic leadership to attract greater financial support and leverage that funding to maximum effect. As Good to Great author Jim Collins writes in his foreword, this book offers "a detailed roadmap of disciplined thought and action for turning a good nonprofit into one that can achieve great impact at scale." William F. Meehan III and Kim Starkey Jonker identify seven essential components of strategic leadership that set high-achieving organizations apart from the rest of the nonprofit sector. Together, these components form an "engine of impact"—a system that organizations must build, tune, and fuel if they hope to make a real difference in the world. Drawing on decades of teaching, advising, grantmaking, and research, Meehan and Jonker provide an actionable guide that executives, staff, board members, and donors can use to jumpstart their own performance and to achieve extraordinary results for their organization. Along with setting forth best practices using real-world examples, the authors outline common management challenges faced by nonprofits, showing how these challenges differ from those faced by for-profit businesses in important and often-overlooked ways. By offering crucial insights on the fundamentals of nonprofit management, this book will help leaders equip their organizations to fire on all cylinders and unleash the full potential of the nonprofit sector. Visit www.engineofimpact.org for additional information.
Book Synopsis Point-of-care testing by : Peter Luppa
Download or read book Point-of-care testing written by Peter Luppa and published by Springer. This book was released on 2018-07-18 with total page 451 pages. Available in PDF, EPUB and Kindle. Book excerpt: The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Book Synopsis Principles of Environmental Engineering by : Yan LIU
Download or read book Principles of Environmental Engineering written by Yan LIU and published by Springer. This book was released on 2022-05-22 with total page 524 pages. Available in PDF, EPUB and Kindle. Book excerpt: This textbook contains the contents coming from hydraulics, hydrodynamics, chemical principles, chemical reaction engineering and bioengineering, which relates closely with fundamental principles in environmental engineering. It mainly covers principles including basic concepts, theories, methods and related equipment in fluid flow and transportation, heat transfer, absorption, chemical and biological reaction kinetics and reactors, as well as their applications in environmental engineering. At same time, the readers learns the basic viewpoints and methods commonly used in engineering technology, such as balance method, reasonable simplification, dimensional analysis method, boundary layer theory, optimization and mathematical model method. It broadens the student’s understanding in solving those problems in environmental engineering, and enhances their awareness of industrialization. This book is the specialized foundation and principles for learning the professional courses of environmental engineering, such as "water pollution control," "air pollution control," "solid waste treatment and disposal" and "ecological restoration engineering", while avoiding the repetition of the contents of those professional books.
Book Synopsis Visionary Manufacturing Challenges for 2020 by : National Research Council
Download or read book Visionary Manufacturing Challenges for 2020 written by National Research Council and published by National Academies Press. This book was released on 1998-12-18 with total page 173 pages. Available in PDF, EPUB and Kindle. Book excerpt: Manufacturing will unquestionably be a very different enterprise in 2020 from what it is today. This book presents an exciting picture of the profitable and productive potential of manufacturing two decades hence. This book takes an international view of future manufacturing that considers the leaps and bounds of technological innovation and the blurring of the lines between the manufacturing and service industries. The authors identify ten strategic technology areas as the most important for research and development and they recommend ways to address crosscutting questions. Representing a variety of industries, the authors identify six "grand challenges" that must be overcome for their vision to be realized, including the human/technology interface, environmental concerns, and miniaturization. A host of issues are discussed that will push and pull at manufacturing over the next 20 years: the changing workforce, the changing consumer, the rise of bio- and nanotechnology, the prospects for waste-free processing, simulation and modeling as design tools, shifts in global competition, and much more. The information and analyses in this book will be vitally important to everyone concerned about the future of manufacturing: policymakers, executives, design and engineering professionals, researchers, faculty, and students.
Book Synopsis GPCR Molecular Pharmacology and Drug Targeting by : Annette Gilchrist
Download or read book GPCR Molecular Pharmacology and Drug Targeting written by Annette Gilchrist and published by John Wiley & Sons. This book was released on 2010-12-10 with total page 675 pages. Available in PDF, EPUB and Kindle. Book excerpt: G protein-coupled receptors (GPCRs) are a large protein family of transmembrane receptors vital in dictating cellular responses. GPCRs are involved in many diseases, but are also the target of around half of all modern medicinal drugs. Shifting Paradigms in G Protein Coupled Receptors takes a look at the way GPCRs are examined today, how they react, how their mutations lead to disease, and the many ways in which they can be screened for compounds that modulate them. Chemists, pharmacologists, and biologists will find essential information in this comprehensive reference.
Book Synopsis The Nordic Corporate Governance Model by : Per Lekvall
Download or read book The Nordic Corporate Governance Model written by Per Lekvall and published by . This book was released on 2015 with total page 289 pages. Available in PDF, EPUB and Kindle. Book excerpt: The Nordic Region is remarkable in many ways and has been the subject of increasing interest over the past years. The five countries of Denmark, Finland, Iceland, Norway and Sweden are culturally closely aligned and combine a well-functioning business sector and high GDP with an expansive welfare state and high taxes. What has been well less known outside the Nordic Region is the shared corporate governance model used by companies and for the first time a comprehensive study is available in English to explain this model.The main part of the study is the condensed presentation of the Nordic CG model. It is based on four country reports covering the three EU Member States (DK, F, S) and one EEA Member State (N). Each country report has been drawn up by a team consisting of a legal expert and a corporate governance expert with practical experience. To ensure that the report reflects actual practices, each team was assisted by a reference group consisting of business practitioners with extensive experience from large-cap listed companies and connections to the national CG code committees. To provide an international aspect, the renowned American scholar Ronald J Gilson contributed a comment on the report's findings in a separate chapter.The key observation of the study is that the Nordic CG model allows the shareholder majority to effectively control and take long-term responsibility for the company that they own. The alleged risk of such a system - the potential that a shareholder majority misuses its power for its own benefit at the expense of minority shareholders - is effectively curbed through a well-developed system of minority protection. The result is a governance model that encourages strong shareholders to engage in the governance of the company in their own interest, while creating value for the company and all its shareholders.
Book Synopsis An Introduction to Global Studies by : Patricia J. Campbell
Download or read book An Introduction to Global Studies written by Patricia J. Campbell and published by John Wiley & Sons. This book was released on 2011-09-13 with total page 441 pages. Available in PDF, EPUB and Kindle. Book excerpt: Taking an interdisciplinary approach, An Introduction to Global Studies presents readers with a solid introduction to the complex, interconnected forces and issues confronting today's globalized world. Introduces readers to major theories, key terms, concepts, and notable theorists Equips readers with the basic knowledge and conceptual tools necessary for thinking critically about the complex issues facing the global community Includes a variety of supplemental features to facilitate learning and enhance readers' understanding of the material
Book Synopsis Pre-ANDA Litigation by : Kenneth L. Dorsney
Download or read book Pre-ANDA Litigation written by Kenneth L. Dorsney and published by American Bar Association. This book was released on 2014 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book is an in-depth resource for learning about and planning for ANDA litigations and all the different avenues that pharmaceutical litigants could follow.
Download or read book River Town written by Peter Hessler and published by Harper Collins. This book was released on 2010-09-21 with total page 382 pages. Available in PDF, EPUB and Kindle. Book excerpt: A New York Times Notable book, this memoir by a journalist who lived in a small city in China is “a vivid and touching tribute to a place and its people” (Kirkus Reviews, starred review). In the heart of China's Sichuan province, amid the terraced hills of the Yangtze River valley, lies the remote town of Fuling. Like many other small cities in this ever-evolving country, Fuling is heading down a new path of change and growth, which came into remarkably sharp focus when Peter Hessler arrived as a Peace Corps volunteer, marking the first time in more than half a century that the city had an American resident. Hessler taught English and American literature at the local college, but it was his students who taught him about the complex processes of understanding that take place when one is immersed in a radically different society. Poignant, thoughtful, funny, and enormously compelling, River Town is an unforgettable portrait of a city that is seeking to understand both what it was and what it someday will be. “This touching memoir of an American dropped into the center of China transcends the boundaries of the travel genre and will appeal to anyone wanting to learn more about the heart and soul of the Chinese people. Highly recommended.” —Library Journal “This is a colorful memoir from a Peace Corps volunteer who came away with more understanding of the Chinese than any foreign traveler has a right to expect.” —Booklist
Book Synopsis The Girl in the Road by : Monica Byrne
Download or read book The Girl in the Road written by Monica Byrne and published by Crown. This book was released on 2014-05-20 with total page 354 pages. Available in PDF, EPUB and Kindle. Book excerpt: A debut that Neil Gaiman calls “Glorious. . . . So sharp, so focused and so human.” The Girl in the Road describes a future that is culturally lush and emotionally wrenching. Monica Byrne bursts on to the literary scene with an extraordinary vision of the future. In a world where global power has shifted east and revolution is brewing, two women embark on vastly different journeys—each harrowing and urgent and wholly unexpected. When Meena finds snakebites on her chest, her worst fears are realized: someone is after her and she must flee India. As she plots her exit, she learns of the Trail, an energy-harvesting bridge spanning the Arabian Sea that has become a refuge for itinerant vagabonds and loners on the run. This is her salvation. Slipping out in the cover of night, with a knapsack full of supplies including a pozit GPS, a scroll reader, and a sealable waterproof pod, she sets off for Ethiopia, the place of her birth. Meanwhile, Mariama, a young girl in Africa, is forced to flee her home. She joins up with a caravan of misfits heading across the Sahara. She is taken in by Yemaya, a beautiful and enigmatic woman who becomes her protector and confidante. They are trying to reach Addis Abba, Ethiopia, a metropolis swirling with radical politics and rich culture. But Mariama will find a city far different than she ever expected—romantic, turbulent, and dangerous. As one heads east and the other west, Meena and Mariama’s fates are linked in ways that are mysterious and shocking to the core. Written with stunning clarity, deep emotion, and a futuristic flair, The Girl in the Road is an artistic feat of the first order: vividly imagined, artfully told, and profoundly moving.
Download or read book Sub-Saharan Africa written by World Bank and published by . This book was released on 1989 with total page 324 pages. Available in PDF, EPUB and Kindle. Book excerpt: 3. Investing in people.